Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant
Bednarski, Jeffrey J., Zimmerman, Clare, Berrien-Elliott, Melissa M., Foltz, Jennifer A., Becker-Hapak, Michelle, Neal, Carly C., Foster, Mark, Schappe, Timothy, McClain, Ethan, Pence, Patrick P., Desai, Sweta, Kersting-Schadek, Samantha, Wong, Pamela, Russler-Germain, David A., Fisk, Bryan, Lie, Wen-Rong, Eisele, Jeremy, Hyde, Stephanie, Bhatt, Sima T., Griffith, Obi L., Griffith, Malachi, Petti, Allegra A., Cashen, Amanda F., Fehniger, Todd A.
Published in Blood (17.03.2022)
Published in Blood (17.03.2022)
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DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs
Bayer, Samantha Vh, Grither, Whitney R, Brenot, Audrey, Hwang, Priscilla Y, Barcus, Craig E, Ernst, Melanie, Pence, Patrick, Walter, Christopher, Pathak, Amit, Longmore, Gregory D
Published in eLife (30.05.2019)
Published in eLife (30.05.2019)
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Memory-like differentiation enhances NK cell responses against colorectal cancer
Marin, Nancy D, Becker-Hapak, Michelle, Song, Wilbur M, Alayo, Quazim A, Marsala, Lynne, Sonnek, Naomi, Berrien-Elliott, Melissa M, Foster, Mark, Foltz, Jennifer A, Tran, Jennifer, Wong, Pamela, Cubitt, Celia C, Pence, Patrick, Hwang, Kimberly, Zhou, Alice Y, Jacobs, Miriam T, Schappe, Timothy, Russler-Germain, David A, Fields, Ryan C, Ciorba, Matthew A, Fehniger, Todd A
Published in Oncoimmunology (2024)
Published in Oncoimmunology (2024)
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Tyrosine kinase-independent actions of DDR2 in tumor cells and cancer-associated fibroblasts influence tumor invasion, migration and metastasis
Barcus, Craig E, Hwang, Priscilla Y, Morikis, Vasilios, Brenot, Audrey, Pence, Patrick, Clarke, Maria, Longmore, Gregory D
Published in Journal of cell science (01.10.2021)
Published in Journal of cell science (01.10.2021)
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Journal Article
Systemic IL-15 promotes allogeneic cell rejection in patients treated with natural killer cell adoptive therapy
Berrien-Elliott, Melissa M., Becker-Hapak, Michelle, Cashen, Amanda F., Jacobs, Miriam, Wong, Pamela, Foster, Mark, McClain, Ethan, Desai, Sweta, Pence, Patrick, Cooley, Sarah, Brunstein, Claudio, Gao, Feng, Abboud, Camille N., Uy, Geoffrey L., Westervelt, Peter, Jacoby, Meagan A., Pusic, Iskra, Stockerl-Goldstein, Keith E., Schroeder, Mark A., DiPersio, John F., Soon-Shiong, Patrick, Miller, Jeffrey S., Fehniger, Todd A.
Published in Blood (24.02.2022)
Published in Blood (24.02.2022)
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Journal Article
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia
Berrien-Elliott, Melissa M, Foltz, Jennifer A, Russler-Germain, David A, Neal, Carly C, Tran, Jennifer, Gang, Margery, Wong, Pamela, Fisk, Bryan, Cubitt, Celia C, Marin, Nancy D, Zhou, Alice Y, Jacobs, Miriam T, Foster, Mark, Schappe, Timothy, McClain, Ethan, Kersting-Schadek, Samantha, Desai, Sweta, Pence, Patrick, Becker-Hapak, Michelle, Eisele, Jeremy, Mosior, Matthew, Marsala, Lynne, Griffith, Obi L, Griffith, Malachi, Khan, Saad M, Spencer, David H, DiPersio, John F, Romee, Rizwan, Uy, Geoffrey L, Abboud, Camille N, Ghobadi, Armin, Westervelt, Peter, Stockerl-Goldstein, Keith, Schroeder, Mark A, Wan, Fei, Lie, Wen-Rong, Soon-Shiong, Patrick, Petti, Allegra A, Cashen, Amanda F, Fehniger, Todd A
Published in Science translational medicine (23.02.2022)
Published in Science translational medicine (23.02.2022)
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Brief IL-12, IL-15, IL-18 activation drives the acquisition of two distinct memory-like NK cell states
Foltz, Jennifer Ann, Tran, Jennifer, Fisk, Bryan, Wong, Pamela, Khan, Saad M., Berrien-Elliott, Melissa M., Becker-Hapak, Michelle, Russler-Germain, David A., Marsala, Lynne, Bednarski, Jeffrey J., Zimmerman, Clare, Cubitt, Celia C., Marin, Nancy D., Zhou, Alice Y., Jacobs, Miriam T., Foster, Mark, Schappe, Timothy, Pence, Patrick, Cashen, Amanda, Griffith, Obi L., Griffith, Malachi, Petti, Allegra A., Fehniger, Todd A
Published in The Journal of immunology (1950) (01.05.2023)
Published in The Journal of immunology (1950) (01.05.2023)
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Journal Article
T-BET and EOMES sustain mature human NK cell identity and antitumor function
Wong, Pamela, Foltz, Jennifer A, Chang, Lily, Neal, Carly C, Yao, Tony, Cubit, Celia C, Tran, Jennifer, Kersting-Schadek, Samantha, Palakurty, Sathvik, Jaeger, Natalia, Russler-Germain, David A, Marin, Nancy D, Gang, Margery, Wagner, Julia A, Zhou, Alice Y, Jacobs, Miriam T, Foster, Mark, Schappe, Timothy, Marsala, Lynne, McClain, Ethan, Pence, Patrick, Becker-Hapak, Michelle, Fisk, Bryan, Petti, Allegra A, Griffith, Obi L, Griffith, Malachi, Berrien-Elliot, Melissa M, Fehniger, Todd A
Published in The Journal of clinical investigation (01.07.2023)
Published in The Journal of clinical investigation (01.07.2023)
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Journal Article
Memory-like Differentiation, Tumor-Targeting mAbs, and Chimeric Antigen Receptors Enhance Natural Killer Cell Responses to Head and Neck Cancer
Jacobs, Miriam T, Wong, Pamela, Zhou, Alice Y, Becker-Hapak, Michelle, Marin, Nancy D, Marsala, Lynne, Foster, Mark, Foltz, Jennifer A, Cubitt, Celia C, Tran, Jennifer, Russler-Germain, David A, Neal, Carly, Kersting-Schadek, Samantha, Chang, Lily, Schappe, Timothy, Pence, Patrick, McClain, Ethan, Zevallos, Jose P, Rich, Jason T, Paniello, Randal C, Jackson, Ryan S, Pipkorn, Patrik, Adkins, Douglas R, DeSelm, Carl J, Berrien-Elliott, Melissa M, Puram, Sidharth V, Fehniger, Todd A
Published in Clinical cancer research (13.10.2023)
Published in Clinical cancer research (13.10.2023)
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Journal Article
A feeder cell-free activation and expansion strategy to generate memory-like NK cells sufficient for off-the-shelf multi-dose adoptive cell therapy
Wong, Hing C, Dee, Michael J, Shrestha, Niraj, Chaturvedi, Pallavi, Leclerc, Giles M, Zhu, Xiaoyun, Liu, Bai, Kong, Lin, Echeverri, Christian A, You, Lijing, Egan, Jack O, Jiao, Jin-An, Rhode, Peter R, Becker-Hapak, Michelle K, Berrien-Elliott, Melissa M, McClain, Ethan, Foster, Mark, Pence, Patrick, Neal, Carly C, Kersting-Schadek, Samantha, Fehniger, Todd A
Published in The Journal of immunology (1950) (01.05.2022)
Published in The Journal of immunology (1950) (01.05.2022)
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Journal Article
T-BET and EOMES sustain mature human NK cell identity and antitumor function
Wong, Pamela, Foltz, Jennifer A, Chang, Lily, Neal, Carly C, Yao, Tony, Cubitt, Celia C, Tran, Jennifer, Kersting-Schadek, Samantha, Palakurty, Sathvik, Jaeger, Natalia, Russler-Germain, David A, Marin, Nancy D, Gang, Margery, Wagner, Julia A, Zhou, Alice Y, Jacobs, Miriam T, Foster, Mark, Schappe, Timothy, Marsala, Lynne, McClain, Ethan, Pence, Patrick, Becker-Hapak, Michelle, Fisk, Bryan, Petti, Allegra A, Griffith, Obi L, Griffith, Malachi, Berrien-Elliott, Melissa M, Fehniger, Todd A
Published in The Journal of clinical investigation (03.07.2023)
Published in The Journal of clinical investigation (03.07.2023)
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Journal Article
Cytokine-Induced Memory-like NK Cells Have a Distinct Single Cell Transcriptional Profile and Persist for Months in Adult and Pediatric Leukemia Patients after Adoptive Transfer
Foltz, Jennifer A., Berrien-Elliott, Melissa M., Russler-Germain, David A., Neal, Carly C., Tran, Jennifer, Gang, Margery, Wong, Pamela, Mosior, Matthew, Bednarski, Jeffrey J., Zimmerman, Clare, Cubitt, Celia C., Marin, Nancy D., Zhou, Alice Y., Jacobs, Miriam T., Foster, Mark, Schappe, Timothy, McClain, Ethan, Desai, Sweta, Pence, Patrick, Becker-Hapak, Michelle, Marsala, Lynne, Griffith, Obi L., Griffith, Malachi, Khan, Saad M., Fisk, Bryan, Cashen, Amanda F., Petti, Allegra A., Fehniger, Todd A.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy
Becker-Hapak, Michelle K, Shrestha, Niraj, McClain, Ethan, Dee, Michael J, Chaturvedi, Pallavi, Leclerc, Gilles M, Marsala, Lynne I, Foster, Mark, Schappe, Timothy, Tran, Jennifer, Desai, Sweta, Neal, Carly C, Pence, Patrick, Wong, Pamela, Wagner, Julia A, Russler-Germain, David A, Zhu, Xiaoyun, Spanoudis, Catherine M, Gallo, Victor L, Echeverri, Christian A, Ramirez, Laritza L, You, Lijing, Egan, Jack O, Rhode, Peter R, Jiao, Jin-An, Muniz, Gabriela J, Jeng, Emily K, Prendes, Caitlin A, Sullivan, Ryan P, Berrien-Elliott, Melissa M, Wong, Hing C, Fehniger, Todd A
Published in Cancer immunology research (01.09.2021)
Published in Cancer immunology research (01.09.2021)
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33. Computational prediction of MHC anchor locations guide neoantigen identification and prioritization
Xia, Huiming, McMichael, Joshua, Becker-Hapak, Michelle, Onyeador, Onyinyechi C., Buchli, Rico, McClain, Ethan, Pence, Patrick, Supabphol, Suangson, Richters, Megan M., Basu, Anamika, Ramirez, Cody A., Puig-Saus, Cristina, Cotto, Kelsy C., Hundal, Jasreet, Kiwala, Susanna, Goedegebuure, S. Peter, Johanns, Tanner M., Dunn, Gavin P., Ribas, Antoni, Miller, Christopher A., Gillanders, William E., Fehniger, Todd A., Griffith, Obi L., Griffith, Malachi
Published in Cancer genetics (01.11.2022)
Published in Cancer genetics (01.11.2022)
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Journal Article
Donor-Derived Memory-like NK Cells for the Treatment of Children and Young Adults with Relapsed AML Following Allo-HCT
Pfeiffer, Thomas, Zimmerman, Clare, Berrien-Elliott, Melissa M, Foltz, Jennifer, Becker-Hapak, Michelle, Neal, Carly, Foster, Mark, Schappe, Timothy, McClain, Ethan, Pence, Patrick, Desai, Sweta, Wong, Pamela, Russler-Germain, David, Fisk, Bryan, Wen-Rong, Lie, Eisele, Jeremy, Hyde, Stephanie, Bhatt, Sima, Griffith, Obi, Griffith, Malachi, Rueve, Joseph, Pureti, Sushanth, Cashen, Amanda, Bednarski, Jeffrey J, Fehniger, Todd A
Published in Transplantation and cellular therapy (01.02.2024)
Published in Transplantation and cellular therapy (01.02.2024)
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Journal Article
Computational prediction of MHC anchor locations guides neoantigen identification and prioritization
Xia, Huiming, McMichael, Joshua, Becker-Hapak, Michelle, Onyeador, Onyinyechi C, Buchli, Rico, McClain, Ethan, Pence, Patrick, Supabphol, Suangson, Richters, Megan M, Basu, Anamika, Ramirez, Cody A, Puig-Saus, Cristina, Cotto, Kelsy C, Freshour, Sharon L, Hundal, Jasreet, Kiwala, Susanna, Goedegebuure, S Peter, Johanns, Tanner M, Dunn, Gavin P, Ribas, Antoni, Miller, Christopher A, Gillanders, William E, Fehniger, Todd A, Griffith, Obi L, Griffith, Malachi
Published in Science immunology (14.04.2023)
Published in Science immunology (14.04.2023)
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Cytokines drive the formation of memory-like NK cell subsets via epigenetic rewiring and transcriptional regulation
Foltz, Jennifer A, Tran, Jennifer, Wong, Pamela, Fan, Changxu, Schmidt, Evelyn, Fisk, Bryan, Becker-Hapak, Michelle, Russler-Germain, David A, Johnson, Jeanette, Marin, Nancy D, Cubitt, Celia C, Pence, Patrick, Rueve, Joseph, Pureti, Sushanth, Hwang, Kimberly, Gao, Feng, Zhou, Alice Y, Foster, Mark, Schappe, Timothy, Marsala, Lynne, Berrien-Elliott, Melissa M, Cashen, Amanda F, Bednarski, Jeffrey J, Fertig, Elana, Griffith, Obi L, Griffith, Malachi, Wang, Ting, Petti, Allegra A, Fehniger, Todd A
Published in Science immunology (28.06.2024)
Published in Science immunology (28.06.2024)
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Abstract 5639: Computational prediction of MHC anchor locations guide neoantigen prediction and prioritization
Xia, Huiming, McMichael, Joshua, Becker-Hapak, Michelle, Onyeador, Onyinyechi C., Buchli, Rico, McClain, Ethan, Pence, Patrick, Supabphol, Suangson, Richters, Megan M., Basu, Anamika, Ramirez, Cody A., Puig-Saus, Cristina, Cotto, Kelsy C., Hundal, Jasreet, Kiwala, Susanna, Goedegebuure, S. Peter, Johanns, Tanner M., Dunn, Gavin P., Ribas, Antoni, Miller, Christopher A., Gillanders, William, Fehniger, Todd A., Griffith, Obi L., Griffith, Malachi
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Computational prediction of MHC anchor locations guide neoantigen identification and prioritization
Xia, Huiming, Mcmichael, Joshua F, Becker-Hapak, Michelle, Onyeador, Onyinyechi C, Buchli, Rico, Mcclain, Ethan, Pence, Patrick, Supabphol, Suangson, Richters, Megan M, Basu, Anamika, Ramirez, Cody A, Puig-Saus, Cristina, Cotto, Kelsy C, Freshour, Sharon L, Hundal, Jasreet, Kiwala, Susanna, Goedegebuure, S Peter, Johanns, Tanner M, Dunn, Gavin P, Ribas, Antoni, Miller, Christopher A, Gillanders, William E, Fehniger, Todd A, Griffith, Obi L, Griffith, Malachi
Published in bioRxiv (31.01.2023)
Published in bioRxiv (31.01.2023)
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