Discovery of 2‑Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods
Pelz, Nicholas F, Bian, Zhiguo, Zhao, Bin, Shaw, Subrata, Tarr, James C, Belmar, Johannes, Gregg, Claire, Camper, DeMarco V, Goodwin, Craig M, Arnold, Allison L, Sensintaffar, John L, Friberg, Anders, Rossanese, Olivia W, Lee, Taekyu, Olejniczak, Edward T, Fesik, Stephen W
Published in Journal of medicinal chemistry (10.03.2016)
Published in Journal of medicinal chemistry (10.03.2016)
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Journal Article
Discovery of a Potent Inhibitor of Replication Protein A Protein–Protein Interactions Using a Fragment-Linking Approach
Frank, Andreas O, Feldkamp, Michael D, Kennedy, J. Phillip, Waterson, Alex G, Pelz, Nicholas F, Patrone, James D, Vangamudi, Bhavatarini, Camper, DeMarco V, Rossanese, Olivia W, Chazin, Walter J, Fesik, Stephen W
Published in Journal of medicinal chemistry (27.11.2013)
Published in Journal of medicinal chemistry (27.11.2013)
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Journal Article
Indazoles: Regioselective Protection and Subsequent Amine Coupling Reactions
Slade, David J, Pelz, Nicholas F, Bodnar, Wanda, Lampe, John W, Watson, Paul S
Published in Journal of organic chemistry (21.08.2009)
Published in Journal of organic chemistry (21.08.2009)
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Journal Article
Palladium-Catalyzed Enantioselective Diboration of Prochiral Allenes
Pelz, Nicholas F, Woodward, Angela R, Burks, Heather E, Sieber, Joshua D, Morken, James P
Published in Journal of the American Chemical Society (22.12.2004)
Published in Journal of the American Chemical Society (22.12.2004)
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Journal Article
Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication ProteinA
Patrone, James D., Pelz, Nicholas F., Bates, Brittney S., Souza-Fagundes, Elaine M., Vangamudi, Bhavatarini, Camper, Demarco V., Kuznetsov, Alexey G., Browning, Carrie F., Feldkamp, Michael D., Frank, Andreas O., Gilston, Benjamin A., Olejniczak, Edward T., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Published in ChemMedChem (19.04.2016)
Published in ChemMedChem (19.04.2016)
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Journal Article
Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A
Patrone, James D., Pelz, Nicholas F., Bates, Brittney S., Souza-Fagundes, Elaine M., Vangamudi, Bhavatarini, Camper, Demarco V., Kuznetsov, Alexey G., Browning, Carrie F., Feldkamp, Michael D., Frank, Andreas O., Gilston, Benjamin A., Olejniczak, Edward T., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Published in ChemMedChem (19.04.2016)
Published in ChemMedChem (19.04.2016)
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Journal Article
Diphenylpyrazoles as Replication Protein A Inhibitors
Waterson, Alex G, Kennedy, J. Phillip, Patrone, James D, Pelz, Nicholas F, Feldkamp, Michael D, Frank, Andreas O, Vangamudi, Bhavatarini, Souza-Fagundes, Elaine M, Rossanese, Olivia W, Chazin, Walter J, Fesik, Stephen W
Published in ACS medicinal chemistry letters (12.02.2015)
Published in ACS medicinal chemistry letters (12.02.2015)
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Journal Article
Discovery of Protein–Protein Interaction Inhibitors of Replication Protein A
Patrone, James D, Kennedy, J. Phillip, Frank, Andreas O, Feldkamp, Michael D, Vangamudi, Bhavatarini, Pelz, Nicholas F, Rossanese, Olivia W, Waterson, Alex G, Chazin, Walter J, Fesik, Stephen W
Published in ACS medicinal chemistry letters (11.07.2013)
Published in ACS medicinal chemistry letters (11.07.2013)
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Journal Article
Abstract 3695: Discovery of probes to evaluate the disruption of the protein-protein interactions mediated by RPA70N
Waterson, Alex G., Kennedy, Phillip, Patrone, James D., Pelz, Nicholas F., Frank, Andreas O., Vangamudi, Bhavatarini, Camper, DeMarco V., Souza-Fagundes, Elaine M., Feldkamp, Michael D., Olejniczak, Edward T., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 2473: Fragment-based discovery of inhibitors of replication protein A protein-protein interactions
Waterson, Alex G., Patrone, James D., Kennedy, J. Phillip, Pelz, Nicholas F., Frank, Andreas O., Vandgamudi, Bhavatarini, Feldkamp, Michael D., Souza-Fagundes, Elaine M., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Diphenylpyrazoles as Replication Protein A Inhibitors
Waterson, Alex G., Kennedy, J. Phillip, Patrone, James D., Pelz, Nicholas F., Feldkamp, Michael D., Frank, Andreas O., Vangamudi, Bhavatarini, Souza-Fagundes, Elaine M., Rossanese, Olivia W., Chazin, Walter J., Fesik, Stephen W.
Published in ACS medicinal chemistry letters (02.12.2014)
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Published in ACS medicinal chemistry letters (02.12.2014)
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SUBSTITUTED INDOLE MCL-1 INHIBITORS
FESIK, STEPHEN W, BIAN, ZHIGUO, ZHAO, BIN, CHRISTOV, PLAMEN P, TARR, JAMES C, LEE, TAEKYU, BELMAR, JOHANNES, KIM, KWANGHO, PELZ, NICHOLAS F, OLEJNICZAK, EDWARD T, SHAW, SUBRATA
Year of Publication 04.04.2023
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Year of Publication 04.04.2023
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Kim, Kwangho, Bian, Zhiguo, Pelz, Nicholas F, Zhao, Bin, Belmar, Johannes, Olejniczak, Edward T, Christov, Plamen P, Shaw, Subrata
Year of Publication 09.02.2023
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Year of Publication 09.02.2023
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Substituted indole Mcl-1 inhibitors
Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Kim, Kwangho, Bian, Zhiguo, Pelz, Nicholas F, Zhao, Bin, Belmar, Johannes, Olejniczak, Edward T, Christov, Plamen P, Shaw, Subrata
Year of Publication 28.12.2021
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Year of Publication 28.12.2021
Patent
SUBSTITUTED INDOLE MCL-1 INHIBITORS
LEE, Taekyu, KIM, Kwangho, OLEJNICZAK, Edward T, TARR, James C, FESIK, Stephen W, SHAW, Subrata, BELMAR, Johannes, CHRISTOV, Plamen P, ZHAO, Bin, PELZ, Nicholas F, BIAN, Zhiguo
Year of Publication 28.10.2020
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Year of Publication 28.10.2020
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Substituted indole Mcl-1 inhibitors
Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Kim, Kwangho, Bian, Zhiguo, Pelz, Nicholas F, Zhao, Bin, Belmar, Johannes, Olejniczak, Edward T, Christov, Plamen P, Shaw, Subrata
Year of Publication 25.06.2020
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Year of Publication 25.06.2020
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SUBSTITUTED INDOLE MCL-1 INHIBITORS
Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Kim, Kwangho, Bian, Zhiguo, Pelz, Nicholas F, Zhao, Bin, Belmar, Johannes, Olejniczak, Edward T, Christov, Plamen P, Shaw, Subrata
Year of Publication 07.05.2020
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Year of Publication 07.05.2020
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Substituted indole Mcl-1 inhibitors
Tarr, James C, Fesik, Stephen W, Lee, Taekyu, Kim, Kwangho, Bian, Zhiguo, Pelz, Nicholas F, Zhao, Bin, Belmar, Johannes, Olejniczak, Edward T, Christov, Plamen P, Shaw, Subrata
Year of Publication 14.01.2020
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Year of Publication 14.01.2020
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SUBSTITUTED BENZOFURAN, BENZOTHIOPHENE AND INDOLE MCL-1 INHIBITORS
Fesik, Stephen W, Chauder, Brian A, Lee, Taekyu, Pelz, Nicholas F, Bian, Zhiguo, Belmar, Johannes, Olejniczak, Edward T
Year of Publication 01.11.2018
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Year of Publication 01.11.2018
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