Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C
Yaeger, Rona, Weiss, Jared, Pelster, Meredith S., Spira, Alexander I., Barve, Minal, Ou, Sai-Hong I., Leal, Ticiana A., Bekaii-Saab, Tanios S., Paweletz, Cloud P., Heavey, Grace A., Christensen, James G., Velastegui, Karen, Kheoh, Thian, Der-Torossian, Hirak, Klempner, Samuel J.
Published in The New England journal of medicine (05.01.2023)
Published in The New England journal of medicine (05.01.2023)
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Journal Article
Nivolumab and Ipilimumab in Metastatic Uveal Melanoma: Results From a Single-Arm Phase II Study
Pelster, Meredith S, Gruschkus, Stephen K, Bassett, Roland, Gombos, Dan S, Shephard, Michael, Posada, Liberty, Glover, Maura S, Simien, Rinata, Diab, Adi, Hwu, Patrick, Carter, Brett W, Patel, Sapna P
Published in Journal of clinical oncology (20.02.2021)
Published in Journal of clinical oncology (20.02.2021)
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Journal Article
Adagrasib in Advanced Solid Tumors Harboring a KRASG12C Mutation
Bekaii-Saab, Tanios S, Yaeger, Rona, Spira, Alexander I, Pelster, Meredith S, Sabari, Joshua K, Hafez, Navid, Barve, Minal, Velastegui, Karen, Yan, Xiaohong, Shetty, Aditya, Der-Torossian, Hirak, Pant, Shubham
Published in Journal of clinical oncology (01.09.2023)
Published in Journal of clinical oncology (01.09.2023)
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Journal Article
Neoadjuvant Immunotherapy for Locally Advanced Melanoma
Pelster, Meredith S., Amaria, Rodabe N.
Published in Current treatment options in oncology (05.02.2020)
Published in Current treatment options in oncology (05.02.2020)
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Journal Article
Adagrasib in Advanced Solid Tumors Harboring a KRAS G12C Mutation
Bekaii-Saab, Tanios S, Yaeger, Rona, Spira, Alexander I, Pelster, Meredith S, Sabari, Joshua K, Hafez, Navid, Barve, Minal, Velastegui, Karen, Yan, Xiaohong, Shetty, Aditya, Der-Torossian, Hirak, Pant, Shubham
Published in Journal of clinical oncology (01.09.2023)
Published in Journal of clinical oncology (01.09.2023)
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Journal Article
Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer
Yaeger, Rona, Uboha, Nataliya V, Pelster, Meredith S, Bekaii-Saab, Tanios S, Barve, Minal, Saltzman, Joel, Sabari, Joshua K, Peguero, Julio A, Paulson, Andrew Scott, Jänne, Pasi A, Cruz-Correa, Marcia, Anderes, Kenna, Velastegui, Karen, Yan, Xiaohong, Der-Torossian, Hirak, Klempner, Samuel J, Kopetz, Scott E
Published in Cancer discovery (03.06.2024)
Published in Cancer discovery (03.06.2024)
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Journal Article
Post-therapy emergence of an NBN reversion mutation in a patient with pancreatic acinar cell carcinoma
Pelster, Meredith S., Silverman, Ian M., Schonhoft, Joseph D., Johnson, Adrienne, Selenica, Pier, Ulanet, Danielle, Rimkunas, Victoria, Reis-Filho, Jorge S.
Published in NPJ precision oncology (01.04.2024)
Published in NPJ precision oncology (01.04.2024)
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Journal Article
652 NT-I7 (efineptakin alfa), a long-acting IL-7, in combination with pembrolizumab improves T cell fitness in heavily pretreated subjects with gastrointestinal tumors
Naing, Aung, Mamdani, Hirva, Barve, Minal, Pelster, Meredith, Haymaker, Cara, Derbala, Mohamed, Goon, Jack, Darko, Samuel, Murphy, Julie, Gorelik, Lauren, Bierly, Allison, Ferrando-Martinez, Sara, Lee, Byung Ha, Yang, Se Hwan, Lee, Siyoung, Chaney, Marya, Kim, Richard D
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
692 COMMANDER-001: safety data from a phase I/II dose escalation/expansion study of SQZ-eAPC-HPV, a cell-based mRNA therapeutic cancer vaccine for HPV16+ solid tumors
Pelster, Meredith, Jimeno, Antonio, Wise-Draper, Trisha, Park, Jong Chul, Villaflor, Victoria, Rodabaugh, Kerry J, Iams, Wade T, Jennings, Julia, Morrison, Melinda, Miselis, Nathan, Loughhead, Scott, Bernstein, Howard, Warren, Marshelle S, Moser, Justin C, Gordon, Michael S
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
611 XTX202–01/02–001, Phase 1/2 first-in human study of XTX202, a masked, tumor-activated IL-2βγ, in patients with advanced solid tumors: results from phase 1
Hanna, Diana, Zakharia, Yousef, Goel, Sanjay, Hurley, Randy, Pelster, Meredith, El-Khoueiry, Anthony, Thomas, Jacob, Powderly, John, Miller, David, Wu, Richard, Chmielowski, Bartosz, Rapisuwon, Suthee, Gupta, Anurag, Duncan, Meghan, Siu, Aika, Patel, Ekta, Fantini, Damiano, Crowe, David, Paramasivan, Sattanathan, Lee, George, Luptakova, Katarina, McKean, Meredith
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Phase 1 study of ASP1002, a bispecific antibody targeting claudin 4 (CLDN4) and CD137, in patients with locally advanced (LA) or metastatic solid tumors that express CLDN4
Pelster, Meredith, Marron, Thomas Urban, Friend, Brian D, Fan, Alan, Yang, Jianning, Spira, Alexander I.
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Journal Article
A phase I study of EO-3021 in adult patients with solid tumors likely to express CLDN18.2
Pelster, Meredith, Perez, Cesar Augusto, Chandana, Sreenivasa R, Uboha, Nataliya Volodymyrivna, Swami, Ashwin, McDonald, Holly, Srivastava, Jaya, Barve, Minal A.
Published in Journal of clinical oncology (20.01.2024)
Published in Journal of clinical oncology (20.01.2024)
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Journal Article
ONCX-NAV-G201: A phase 2 basket study of navicixizumab monotherapy or in combination with chemotherapy in patients with select advanced solid tumors—Colorectal Cancer Cohort (trial in progress)
Oberstein, Paul Eliezer, Pelster, Meredith, Culm, Kerry, Chamberlain Santos, Valerie, Koustenis, Andrew, Mockbee, Colleen M., Youssoufian, Hagop, Krauss, John C.
Published in Journal of clinical oncology (01.02.2023)
Published in Journal of clinical oncology (01.02.2023)
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Journal Article
A multicenter, open-label, phase 1a/b study of HC-7366, a modulator of integrated stress response (ISR) kinase GCN2 in subjects with advanced solid tumors
Pelster, Meredith, Torre, Marcio, Kannan, Geoffrey Sumithran, Gargano, Michele Anne, Mattson, Paulette, Rathmann, Blaine, Bose, Nandita, Iglesias, Jose Luis
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Preliminary results of a phase 1/2, first-in-human, open-label, dose escalation study of ZL-1211 (anti-Claudin 18.2 mAb) in patients with unresectable or metastatic solid tumors
Sharma, Sunil, Starodub, Alexander, Xu, Nong, Chaudhry, Arvind, Sun, Meili, Pelster, Meredith, Fu, Yinjia, Zhang, Xinyu, Huang, Zhao, Liu, Wenyu, Hsu, Karl
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Tumor infiltrating lymphocyte (TIL) harvest and ex vivo expansion from primary and metastatic (met) uveal melanoma (UM) tumors
Patel, Sapna Pradyuman, Forget, Marie-Andree, Kreidieh, Firas Y., Pelster, Meredith, Davies, Michael A., Amaria, Rodabe Navroze, Gombos, Dan S., Bernatchez, Chantale
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
A phase 1/2, first-in-human trial of ZB131, a novel antibody targeting cancer-specific plectin (CSP) in advanced solid tumors
Sommerhalder, David, Piha-Paul, Sarina A., Pelster, Meredith, Borad, Mitesh J., Vandross, Andrae Lavon, Spira, Alexander I., Perez, Samantha, Brinton, Lindsey, Kelly, Kimberly, Ramanathan, Ramesh K., Reilley, Matthew
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
KRYSTAL-1: Activity and safety of adagrasib (MRTX849) in patients with advanced solid tumors harboring a KRAS G12C mutation
Pant, Shubham, Yaeger, Rona, Spira, Alexander I., Pelster, Meredith, Sabari, Joshua K., Hafez, Navid, Barve, Minal A., Velastegui, Karen, Yan, Xiaohong, Der-Torossian, Hirak, Bekaii-Saab, Tanios S.
Published in Journal of clinical oncology (20.04.2023)
Published in Journal of clinical oncology (20.04.2023)
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Journal Article