A transcriptional switch governs fibroblast activation in heart disease
Alexanian, Michael, Przytycki, Pawel F., Micheletti, Rudi, Padmanabhan, Arun, Ye, Lin, Travers, Joshua G., Gonzalez-Teran, Barbara, Silva, Ana Catarina, Duan, Qiming, Ranade, Sanjeev S., Felix, Franco, Linares-Saldana, Ricardo, Li, Li, Lee, Clara Youngna, Sadagopan, Nandhini, Pelonero, Angelo, Huang, Yu, Andreoletti, Gaia, Jain, Rajan, McKinsey, Timothy A., Rosenfeld, Michael G., Gifford, Casey A., Pollard, Katherine S., Haldar, Saptarsi M., Srivastava, Deepak
Published in Nature (London) (15.07.2021)
Published in Nature (London) (15.07.2021)
Get full text
Journal Article
An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish
Zou, Jun, Tran, Diana, Baalbaki, Mai, Tang, Ling Fung, Poon, Annie, Pelonero, Angelo, Titus, Erron W, Yuan, Christiana, Shi, Chenxu, Patchava, Shruthi, Halper, Elizabeth, Garg, Jasmine, Movsesyan, Irina, Yin, Chaoying, Wu, Roland, Wilsbacher, Lisa D, Liu, Jiandong, Hager, Ronald L, Coughlin, Shaun R, Jinek, Martin, Pullinger, Clive R, Kane, John P, Hart, Daniel O, Kwok, Pui-Yan, Deo, Rahul C
Published in eLife (16.10.2015)
Published in eLife (16.10.2015)
Get full text
Journal Article
Abstract 14797: Single Cell Multi-Modal Analyses Reveal Epigenomic and Transcriptomic Basis Underlying Cardiac Defects in Maternal Diabetes
Nishino, Tomohiro, Ranade, Sanjeev, Angelo, Pelonero, van Soldt, Benjamin J, Ye, Lin, Alexanian, Michael, Koback, Frances, Huang, Yu, Sadagopan, Nandhini, Padmanabhan, Arun, Thomas, Reuben, van Bemmel, Joke, Gifford, Casey, Costa, Mauro, Srivastava, Deepak
Published in Circulation (New York, N.Y.) (08.11.2022)
Published in Circulation (New York, N.Y.) (08.11.2022)
Get full text
Journal Article
Abstract 64: An Integrated Model for Titin Truncation Mutation Interpretation
Zou, Jun, Tran, Diana, Pelonero, Angelo, Deo, Rahul C
Published in Circulation research (22.07.2016)
Published in Circulation research (22.07.2016)
Get full text
Journal Article
Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors
Zhu, Lili, Choudhary, Krishna, Gonzalez-Teran, Barbara, Ang, Yen-Sin, Thomas, Reuben, Stone, Nicole R, Liu, Lei, Zhou, Ping, Zhu, Chenchen, Ruan, Hongmei, Huang, Yu, Jin, Shibo, Pelonero, Angelo, Koback, Frances, Padmanabhan, Arun, Sadagopan, Nandhini, Hsu, Austin, Costa, Mauro W, Gifford, Casey A, van Bemmel, Joke G, Hüttenhain, Ruth, Vedantham, Vasanth, Conklin, Bruce R, Black, Brian L, Bruneau, Benoit G, Steinmetz, Lars, Krogan, Nevan J, Pollard, Katherine S, Srivastava, Deepak
Published in Circulation (New York, N.Y.) (06.09.2022)
Published in Circulation (New York, N.Y.) (06.09.2022)
Get full text
Journal Article
Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor
Smith, Geoffrey A, Padmanabhan, Arun, Lau, Bryan H, Pampana, Akhil, Li, Li, Lee, Clara Y, Pelonero, Angelo, Nishino, Tomohiro, Sadagopan, Nandhini, Xia, Vivian Q, Jain, Rajan, Natarajan, Pradeep, Wu, Roland S, Black, Brian L, Srivastava, Deepak, Shokat, Kevan M, Chorba, John S
Published in Science translational medicine (14.09.2022)
Published in Science translational medicine (14.09.2022)
Get more information
Journal Article
Chromatin remodelling drives immune cell-fibroblast communication in heart failure
Alexanian, Michael, Padmanabhan, Arun, Nishino, Tomohiro, Travers, Joshua G, Ye, Lin, Pelonero, Angelo, Lee, Clara Youngna, Sadagopan, Nandhini, Huang, Yu, Auclair, Kirsten, Zhu, Ada, An, Yuqian, Ekstrand, Christina A, Martinez, Cassandra, Teran, Barbara Gonzalez, Flanigan, Will R, Kim, Charis Kee-Seon, Lumbao-Conradson, Koya, Gardner, Zachary, Li, Li, Costa, Mauro W, Jain, Rajan, Charo, Israel, Combes, Alexis J, Haldar, Saptarsi M, Pollard, Katherine S, Vagnozzi, Ronald J, McKinsey, Timothy A, Przytycki, Pawel F, Srivastava, Deepak
Published in Nature (London) (23.10.2024)
Published in Nature (London) (23.10.2024)
Get full text
Journal Article
The Transcription Factor GATA4 Regulates Cell Type-Specific Splicing through Direct Interaction with RNA in Human iPS-Derived Cardiac Progenitors
Zhu, Lili, Choudhary, Krishna, Gonzalez-Teran, Barbara, Ang, Yen-Sin, Thomas, Reuben, Stone, Nicole R., Liu, Lei, Zhou, Ping, Zhu, Chenchen, Ruan, Hongmei, Huang, Yu, Jin, Shibo, Pelonero, Angelo, Koback, Frances, Padmanabhan, Arun, Sadagopan, Nandhini, Hsu, Austin, Costa, Mauro W., Gifford, Casey A., van Bemmel, Joke, Hüttenhain, Ruth, Vedantham, Vasanth, Conklin, Bruce R., Black, Brian L., Bruneau, Benoit G., Steinmetz, Lars, Krogan, Nevan J., Pollard, Katherine S., Srivastava, Deepak
Published in Circulation (New York, N.Y.) (08.08.2022)
Published in Circulation (New York, N.Y.) (08.08.2022)
Get full text
Journal Article
The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5
Maven, Bonnie E.J., Gifford, Casey A., Weilert, Melanie, Gonzalez-Teran, Barbara, Hüttenhain, Ruth, Pelonero, Angelo, Ivey, Kathryn N., Samse-Knapp, Kaitlen, Kwong, Wesley, Gordon, David, McGregor, Michael, Nishino, Tomohiro, Okorie, Eyuche, Rossman, Sage, Costa, Mauro W., Krogan, Nevan J., Zeitlinger, Julia, Srivastava, Deepak
Published in Stem cell reports (14.11.2023)
Published in Stem cell reports (14.11.2023)
Get full text
Journal Article
Single Cell Multimodal Analyses Reveal Epigenomic and Transcriptomic Basis for Birth Defects in Maternal Diabetes
Nishino, Tomohiro, Ranade, Sanjeev S, Pelonero, Angelo, van Soldt, Benjamin J, Ye, Lin, Alexanian, Michael, Koback, Frances, Huang, Yu, Sadagopan, Nandhini, Lam, Adrienne, Zholudeva, Lyandysha V, Li, Feiya, Padmanabhan, Arun, Thomas, Reuben, van Bemmel, Joke G, Gifford, Casey A, Costa, Mauro W, Srivastava, Deepak
Published in Nature cardiovascular research (01.12.2023)
Published in Nature cardiovascular research (01.12.2023)
Get more information
Journal Article
A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation
Padmanabhan, Arun, de Soysa, T Yvanka, Pelonero, Angelo, Sapp, Valerie, Shah, Parisha P, Wang, Qiaohong, Li, Li, Lee, Clara Youngna, Sadagopan, Nandhini, Nishino, Tomohiro, Ye, Lin, Yang, Rachel, Karnay, Ashley, Poleshko, Andrey, Bolar, Nikhita, Linares-Saldana, Ricardo, Ranade, Sanjeev S, Alexanian, Michael, Morton, Sarah U, Jain, Mohit, Haldar, Saptarsi M, Srivastava, Deepak, Jain, Rajan
Published in Nature cardiovascular research (01.03.2024)
Published in Nature cardiovascular research (01.03.2024)
Get more information
Journal Article
Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis
Alexanian, Michael, Padmanabhan, Arun, Nishino, Tomohiro, Travers, Joshua G, Ye, Lin, Lee, Clara Youngna, Sadagopan, Nandhini, Huang, Yu, Pelonero, Angelo, Auclair, Kirsten, Zhu, Ada, Teran, Barbara Gonzalez, Flanigan, Will, Kim, Charis Kee-Seon, Lumbao-Conradson, Koya, Costa, Mauro, Jain, Rajan, Charo, Israel, Haldar, Saptarsi M, Pollard, Katherine S, Vagnozzi, Ronald J, McKinsey, Timothy A, Przytycki, Pawel F, Srivastava, Deepak
Published in bioRxiv : the preprint server for biology (07.01.2023)
Get more information
Published in bioRxiv : the preprint server for biology (07.01.2023)
Journal Article
CSDE1 is a Post-Transcriptional Regulator of the LDL Receptor
Smith, Geoffrey A, Padmanabhan, Arun, Lau, Bryan H, Pampana, Akhil, Li, Li, Lee, Youngna Clara, Pelonero, Angelo, Nishino, Tomohiro, Sadagopan, Nandhini, Jain, Rajan, Natarajan, Pradeep, Wu, Roland S, Black, Brian L, Srivastava, Deepak, Shokat, Kevan, Chorba, John S
Published in bioRxiv (27.06.2021)
Published in bioRxiv (27.06.2021)
Get full text
Paper
Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis
Alexanian, Michael, Padmanabhan, Arun, Nishino, Tomohiro, Travers, Joshua G, Lin, Ye, Lee, Clara Youngna, Sadagopan, Nandhini, Huang, Yu, Pelonero, Angelo, Auclair, Kirsten, Zhu, Ada, Barbara Gonzalez Teran, Flanigan, Will, Kim, Charis Kee-Seon, Lumbao-Conradson, Koya, Costa, Mauro, Jain, Rajan, Charo, Israel, Haldar, Saptarsi M, Pollard, Katherine S, Vagnozzi, Ronald J, Mckinsey, Timothy A, Przytycki, Pawel F, Srivastava, Deepak
Published in bioRxiv (07.01.2023)
Published in bioRxiv (07.01.2023)
Get full text
Paper