A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury
Chouchani, Edward T., Pell, Victoria R., James, Andrew M., Work, Lorraine M., Saeb-Parsy, Kourosh, Frezza, Christian, Krieg, Thomas, Murphy, Michael P.
Published in Cell metabolism (09.02.2016)
Published in Cell metabolism (09.02.2016)
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Journal Article
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Chouchani, Edward T., Pell, Victoria R., Gaude, Edoardo, Aksentijević, Dunja, Sundier, Stephanie Y., Robb, Ellen L., Logan, Angela, Nadtochiy, Sergiy M., Ord, Emily N. J., Smith, Anthony C., Eyassu, Filmon, Shirley, Rachel, Hu, Chou-Hui, Dare, Anna J., James, Andrew M., Rogatti, Sebastian, Hartley, Richard C., Eaton, Simon, Costa, Ana S. H., Brookes, Paul S., Davidson, Sean M., Duchen, Michael R., Saeb-Parsy, Kourosh, Shattock, Michael J., Robinson, Alan J., Work, Lorraine M., Frezza, Christian, Krieg, Thomas, Murphy, Michael P.
Published in Nature (London) (20.11.2014)
Published in Nature (London) (20.11.2014)
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Journal Article
MitoNeoD: A Mitochondria-Targeted Superoxide Probe
Shchepinova, Maria M., Cairns, Andrew G., Prime, Tracy A., Logan, Angela, James, Andrew M., Hall, Andrew R., Vidoni, Sara, Arndt, Sabine, Caldwell, Stuart T., Prag, Hiran A., Pell, Victoria R., Krieg, Thomas, Mulvey, John F., Yadav, Pooja, Cobley, James N., Bright, Thomas P., Senn, Hans M., Anderson, Robert F., Murphy, Michael P., Hartley, Richard C.
Published in Cell chemical biology (19.10.2017)
Published in Cell chemical biology (19.10.2017)
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Journal Article
Ischemic preconditioning protects against cardiac ischemia reperfusion injury without affecting succinate accumulation or oxidation
Pell, Victoria R., Spiroski, Ana-Mishel, Mulvey, John, Burger, Nils, Costa, Ana S.H., Logan, Angela, Gruszczyk, Anja V., Rosa, Tiziana, James, Andrew M., Frezza, Christian, Murphy, Michael P., Krieg, Thomas
Published in Journal of molecular and cellular cardiology (01.10.2018)
Published in Journal of molecular and cellular cardiology (01.10.2018)
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Journal Article
Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry
Logan, Angela, Pell, Victoria R., Shaffer, Karl J., Evans, Cameron, Stanley, Nathan J., Robb, Ellen L., Prime, Tracy A., Chouchani, Edward T., Cochemé, Helena M., Fearnley, Ian M., Vidoni, Sara, James, Andrew M., Porteous, Carolyn M., Partridge, Linda, Krieg, Thomas, Smith, Robin A.J., Murphy, Michael P.
Published in Cell metabolism (09.02.2016)
Published in Cell metabolism (09.02.2016)
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Journal Article
Metabolomic Profiling in Acute ST‐Segment–Elevation Myocardial Infarction Identifies Succinate as an Early Marker of Human Ischemia–Reperfusion Injury
Kohlhauer, Matthias, Dawkins, Sam, Costa, Ana S. H., Lee, Regent, Young, Timothy, Pell, Victoria R., Choudhury, Robin P., Banning, Adrian P., Kharbanda, Rajesh K., Saeb‐Parsy, Kourosh, Murphy, Michael P., Frezza, Christian, Krieg, Thomas, Channon, Keith M.
Published in Journal of the American Heart Association (17.04.2018)
Published in Journal of the American Heart Association (17.04.2018)
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Journal Article
Succinate metabolism: a new therapeutic target for myocardial reperfusion injury
Pell, Victoria R, Chouchani, Edward T, Frezza, Christian, Murphy, Michael P, Krieg, Thomas
Published in Cardiovascular research (15.07.2016)
Published in Cardiovascular research (15.07.2016)
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Journal Article
Moving Forwards by Blocking Back-Flow: The Yin and Yang of MI Therapy
Pell, Victoria R, Chouchani, Edward T, Murphy, Michael P, Brookes, Paul S, Krieg, Thomas
Published in Circulation research (04.03.2016)
Published in Circulation research (04.03.2016)
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Journal Article
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I
Chouchani, Edward T, Methner, Carmen, Nadtochiy, Sergiy M, Logan, Angela, Pell, Victoria R, Ding, Shujing, James, Andrew M, Cochemé, Helena M, Reinhold, Johannes, Lilley, Kathryn S, Partridge, Linda, Fearnley, Ian M, Robinson, Alan J, Hartley, Richard C, Smith, Robin A J, Krieg, Thomas, Brookes, Paul S, Murphy, Michael P
Published in Nature medicine (01.06.2013)
Published in Nature medicine (01.06.2013)
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Journal Article
A Reactivity-Based 18 F-Labeled Probe for PET Imaging of Oxidative Stress in Chemotherapy-Induced Cardiotoxicity
Mota, Filipa, Pell, Victoria R, Singh, Nisha, Baark, Friedrich, Waters, Edward, Sadasivam, Pragalath, Southworth, Richard, Yan, Ran
Published in Molecular pharmaceutics (03.01.2022)
Published in Molecular pharmaceutics (03.01.2022)
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Journal Article
A Reactivity-Based 18F‑Labeled Probe for PET Imaging of Oxidative Stress in Chemotherapy-Induced Cardiotoxicity
Mota, Filipa, Pell, Victoria R, Singh, Nisha, Baark, Friedrich, Waters, Edward, Sadasivam, Pragalath, Southworth, Richard, Yan, Ran
Published in Molecular pharmaceutics (03.01.2022)
Published in Molecular pharmaceutics (03.01.2022)
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Journal Article
Identification and quantification of protein S-nitrosation by nitrite in the mouse heart during ischemia
Chouchani, Edward T., James, Andrew M., Methner, Carmen, Pell, Victoria R., Prime, Tracy A., Erickson, Brian K., Forkink, Marleen, Lau, Gigi Y., Bright, Thomas P., Menger, Katja E., Fearnley, Ian M., Krieg, Thomas, Murphy, Michael P.
Published in The Journal of biological chemistry (01.09.2017)
Published in The Journal of biological chemistry (01.09.2017)
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Journal Article
Mitochondria selective S-nitrosation by mitochondria-targeted S-nitrosothiol protects against post-infarct heart failure in mouse hearts
Methner, Carmen, Chouchani, Edward T., Buonincontri, Guido, Pell, Victoria R., Sawiak, Stephen J., Murphy, Michael P., Krieg, Thomas
Published in European journal of heart failure (01.07.2014)
Published in European journal of heart failure (01.07.2014)
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Journal Article
Detection of anthracycline-induced cardiotoxicity using perfusion-corrected 99mTc sestamibi SPECT
Safee, Zaitulhusna M., Baark, Friedrich, Waters, Edward C. T., Veronese, Mattia, Pell, Victoria R., Clark, James E., Mota, Filipa, Livieratos, Lefteris, Eykyn, Thomas R., Blower, Philip J., Southworth, Richard
Published in Scientific reports (18.01.2019)
Published in Scientific reports (18.01.2019)
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Journal Article
Tissue acidosis does not mediate the hypoxia selectivity of [64Cu][Cu(ATSM)] in the isolated perfused rat heart
Baark, Friedrich, Shaughnessy, Fiona, Pell, Victoria R., Clark, James E., Eykyn, Thomas R., Blower, Philip, Southworth, Richard
Published in Scientific reports (24.01.2019)
Published in Scientific reports (24.01.2019)
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Journal Article
Using exomarkers to assess mitochondrial reactive species in vivo
Logan, Angela, Cochemé, Helena M., Li Pun, Pamela Boon, Apostolova, Nadezda, Smith, Robin A.J., Larsen, Lesley, Larsen, David S., James, Andrew M., Fearnley, Ian M., Rogatti, Sebastian, Prime, Tracy A., Finichiu, Peter G., Dare, Anna, Chouchani, Edward T., Pell, Victoria R., Methner, Carmen, Quin, Caroline, McQuaker, Stephen J., Krieg, Thomas, Hartley, Richard C., Murphy, Michael P.
Published in Biochimica et biophysica acta (01.02.2014)
Published in Biochimica et biophysica acta (01.02.2014)
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Journal Article
Comparison of human ETA and ETB receptor signalling via G-protein and β-arrestin pathways
Maguire, Janet J., Kuc, Rhoda E., Pell, Victoria R., Green, Andrew, Brown, Mike, Kumar, Sanj, Wehrman, Tom, Quinn, Elizabeth, Davenport, Anthony P.
Published in Life sciences (1973) (15.10.2012)
Published in Life sciences (1973) (15.10.2012)
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Journal Article
Detection of anthracycline-induced cardiotoxicity using perfusion-corrected 99m Tc sestamibi SPECT
Safee, Zaitulhusna M, Baark, Friedrich, Waters, Edward C T, Veronese, Mattia, Pell, Victoria R, Clark, James E, Mota, Filipa, Livieratos, Lefteris, Eykyn, Thomas R, Blower, Philip J, Southworth, Richard
Published in Scientific reports (18.01.2019)
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Published in Scientific reports (18.01.2019)
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