Altered mechanobiology of Schlemm’s canal endothelial cells in glaucoma
Overby, Darryl R., Zhou, Enhua H., Vargas-Pinto, Rocio, Pedrigi, Ryan M., Fuchshofer, Rudolf, Braakman, Sietse T., Gupta, Ritika, Perkumas, Kristin M., Sherwood, Joseph M., Vahabikashi, Amir, Dang, Quynh, Kim, Jae Hun, Ethier, C. Ross, Stamer, W. Daniel, Fredberg, Jeffrey J., Johnson, Mark
Published in Proceedings of the National Academy of Sciences - PNAS (23.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (23.09.2014)
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Journal Article
Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis
Liu, Martin, Samant, Saurabhi, Vasa, Charu Hasini, Pedrigi, Ryan M, Oguz, Usama M, Ryu, Sangjin, Wei, Timothy, Anderson, Daniel R, Agrawal, Devendra K, Chatzizisis, Yiannis S
Published in PloS one (20.01.2023)
Published in PloS one (20.01.2023)
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Journal Article
Mammalian synthetic biology: emerging medical applications
Kis, Zoltán, Pereira, Hugo Sant'Ana, Homma, Takayuki, Pedrigi, Ryan M., Krams, Rob
Published in Journal of the Royal Society interface (06.05.2015)
Published in Journal of the Royal Society interface (06.05.2015)
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Journal Article
Smooth muscle cells affect differential nanoparticle accumulation in disturbed blood flow-induced murine atherosclerosis
Miller, Hunter A, Schake, Morgan A, Bony, Badrul Alam, Curtis, Evan T, Gee, Connor C, McCue, Ian S, Ripperda, Jr, Thomas J, Chatzizisis, Yiannis S, Kievit, Forrest M, Pedrigi, Ryan M
Published in PloS one (09.12.2021)
Published in PloS one (09.12.2021)
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Journal Article
Restoration of normal blood flow in atherosclerotic arteries promotes plaque stabilization
Schake, Morgan A., McCue, Ian S., Curtis, Evan T., Ripperda, Thomas J., Harvey, Samuel, Hackfort, Bryan T., Fitzwater, Anna, Chatzizisis, Yiannis S., Kievit, Forrest M., Pedrigi, Ryan M.
Published in iScience (16.06.2023)
Published in iScience (16.06.2023)
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Journal Article
Influence of shear stress magnitude and direction on atherosclerotic plaque composition
Pedrigi, Ryan M., Mehta, Vikram V., Bovens, Sandra M., Mohri, Zahra, Poulsen, Christian Bo, Gsell, Willy, Tremoleda, Jordi L., Towhidi, Leila, de Silva, Ranil, Petretto, Enrico, Krams, Rob
Published in Royal Society open science (01.10.2016)
Published in Royal Society open science (01.10.2016)
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Journal Article
Quantification of plaque stiffness by Brillouin microscopy in experimental thin cap fibroatheroma
Antonacci, Giuseppe, Pedrigi, Ryan M., Kondiboyina, Avinash, Mehta, Vikram V., de Silva, Ranil, Paterson, Carl, Krams, Rob, Török, Peter
Published in Journal of the Royal Society interface (06.11.2015)
Published in Journal of the Royal Society interface (06.11.2015)
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Journal Article
Altered stress field of the human lens capsule after cataract surgery
Berggren, Caleb C., Ameku, Kurt A., Pedrigi, Ryan M.
Published in Journal of biomechanics (22.01.2021)
Published in Journal of biomechanics (22.01.2021)
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Journal Article
Ultrasound Induces Similar Temporal Endothelial Expression Patterns of eNOS and KLF2 as Normal Flow
Sahni, Jaideep, McCue, Ian S., Johnson, Adam R., Schake, Morgan A., Sotelo, Luz D., Turner, Joseph A., Pedrigi, Ryan M.
Published in Ultrasound in medicine & biology (01.12.2024)
Published in Ultrasound in medicine & biology (01.12.2024)
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Journal Article
Considerations for analysis of endothelial shear stress and strain in FSI models of atherosclerosis
Patel, Miten, Savvopoulos, Fotios, Berggren, Caleb C., Aslanidou, Lydia, Timmins, Lucas H., de Silva, Ranil, Pedrigi, Ryan M., Krams, Rob
Published in Journal of biomechanics (09.11.2021)
Published in Journal of biomechanics (09.11.2021)
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Journal Article
Integration of flow studies for robust selection of mechanoresponsive genes
Maimari, Nataly, Pedrigi, Ryan M, Russo, Alessandra, Broda, Krysia, Krams, Rob
Published in Thrombosis and haemostasis (01.03.2016)
Published in Thrombosis and haemostasis (01.03.2016)
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Journal Article
Considering the Influence of Coronary Motion on Artery-Specific Biomechanics Using Fluid–Structure Interaction Simulation
Fogell, Nicholas A. T., Patel, Miten, Yang, Pan, Ruis, Roosje M., Garcia, David B., Naser, Jarka, Savvopoulos, Fotios, Davies Taylor, Clint, Post, Anouk L., Pedrigi, Ryan M., de Silva, Ranil, Krams, Rob
Published in Annals of biomedical engineering (01.09.2023)
Published in Annals of biomedical engineering (01.09.2023)
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Journal Article
Characterizing nuclear morphology and expression of eNOS in vascular endothelial cells subjected to a continuous range of wall shear stress magnitudes and directionality
Sahni, Jaideep, Arshad, Mehwish, Schake, Morgan A., Brooks, Justin R., Yang, Ruiguo, Weinberg, Peter D., Pedrigi, Ryan M.
Published in Journal of the mechanical behavior of biomedical materials (01.01.2023)
Published in Journal of the mechanical behavior of biomedical materials (01.01.2023)
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Journal Article
Inducing Persistent Flow Disturbances Accelerates Atherogenesis and Promotes Thin Cap Fibroatheroma Development in D374Y-PCSK9 Hypercholesterolemic Minipigs
Pedrigi, Ryan M, Poulsen, Christian Bo, Mehta, Vikram V, Ramsing Holm, Niels, Pareek, Nilesh, Post, Anouk L, Kilic, Ismail Dogu, Banya, Winston A.S, Dall’Ara, Gianni, Mattesini, Alessio, Bjørklund, Martin M, Andersen, Niels P, Grøndal, Anna K, Petretto, Enrico, Foin, Nicolas, Davies, Justin E, Di Mario, Carlo, Fog Bentzon, Jacob, Erik Bøtker, Hans, Falk, Erling, Krams, Rob, de Silva, Ranil
Published in Circulation (New York, N.Y.) (15.09.2015)
Published in Circulation (New York, N.Y.) (15.09.2015)
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Journal Article
Systems biology of the functional and dysfunctional endothelium
Frueh, Jennifer, Maimari, Nataly, Homma, Takayuki, Bovens, Sandra M, Pedrigi, Ryan M, Towhidi, Leila, Krams, Rob
Published in Cardiovascular research (15.07.2013)
Published in Cardiovascular research (15.07.2013)
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Journal Article
Disturbed Cyclical Stretch of Endothelial Cells Promotes Nuclear Expression of the Pro-Atherogenic Transcription Factor NF-κB
Pedrigi, Ryan M., Papadimitriou, Konstantinos I., Kondiboyina, Avinash, Sidhu, Sukhjinder, Chau, James, Patel, Miten B., Baeriswyl, Daniel C., Drakakis, Emmanuel M., Krams, Rob
Published in Annals of biomedical engineering (01.04.2017)
Published in Annals of biomedical engineering (01.04.2017)
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Journal Article
Biomechanical strain as a trigger for pore formation in Schlemm's canal endothelial cells
Braakman, Sietse T., Pedrigi, Ryan M., Read, A. Thomas, Smith, James A.E., Stamer, W. Daniel, Ethier, C. Ross, Overby, Darryl R.
Published in Experimental eye research (01.10.2014)
Published in Experimental eye research (01.10.2014)
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Journal Article