Glucuronidation of Statins in Animals and Humans: A Novel Mechanism of Statin Lactonization
PRUEKSARITANONT, Thomayant, SUBRAMANIAN, Raju, XIAOJUN FANG, MA, Bennett, YUE QIU, LIN, Jiunn H, PEARSON, Paul G, BAILLIE, Thomas A
Published in Drug metabolism and disposition (01.05.2002)
Published in Drug metabolism and disposition (01.05.2002)
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Mechanistic Studies on Metabolic Interactions between Gemfibrozil and Statins
Prueksaritanont, Thomayant, Zhao, Jamie J, Ma, Bennett, Roadcap, Brad A, Tang, Cuyue, Qiu, Yue, Liu, Lida, Lin, Jiunn H, Pearson, Paul G, Baillie, Thomas A
Published in The Journal of pharmacology and experimental therapeutics (01.06.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2002)
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Studies on the Metabolism of Troglitazone to Reactive Intermediates in Vitro and in Vivo. Evidence for Novel Biotransformation Pathways Involving Quinone Methide Formation and Thiazolidinedione Ring Scission
Kassahun, Kelem, Pearson, Paul G, Tang, Wei, McIntosh, Ian, Leung, Kwan, Elmore, Charles, Dean, Dennis, Wang, Regina, Doss, George, Baillie, Thomas A
Published in Chemical research in toxicology (01.01.2001)
Published in Chemical research in toxicology (01.01.2001)
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Disposition of Caspofungin: Role of Distribution in Determining Pharmacokinetics in Plasma
STONE, Julie A, XIN XU, SINGH, Romi, DELUNA, Florencia, DILZER, Stacy C, LASSETER, Kenneth C, WINCHELL, Gregory A, DEUTSCH, Paul J, PEARSON, Paul G, MIGOYA, Elizabeth M, MISTRY, Goutam C, LIWEN XI, MILLER, Alisha, SANDHU, Punam
Published in Antimicrobial Agents and Chemotherapy (01.03.2004)
Published in Antimicrobial Agents and Chemotherapy (01.03.2004)
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EVALUATION OF MICRODOSING STRATEGIES FOR STUDIES IN PRECLINICAL DRUG DEVELOPMENT: DEMONSTRATION OF LINEAR PHARMACOKINETICS IN DOGS OF A NUCLEOSIDE ANALOG OVER A 50-FOLD DOSE RANGE
SANDHU, Punam, VOGEL, John S, BAILLIE, Thomas A, ROSE, Mark J, UBICK, Esther A, BRUNNER, Janice E, WALLACE, Michael A, ADELSBERGER, Jennifer K, BAKER, Maribeth P, HENDERSON, Paul T, PEARSON, Paul G
Published in Drug metabolism and disposition (01.11.2004)
Published in Drug metabolism and disposition (01.11.2004)
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Copy number variations in three children with sudden infant death
Toruner, GA, Kurvathi, R, Sugalski, R, Shulman, L, Twersky, S, Pearson, PG, Tozzi, R, Schwalb, MN, Wallerstein, R
Published in Clinical genetics (01.07.2009)
Published in Clinical genetics (01.07.2009)
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Disposition of Caspofungin, a Novel Antifungal Agent, in Mice, Rats, Rabbits, and Monkeys
SANDHU, Punam, XIN XU, BONDISKEY, Peter J, BALANI, Suresh K, MORRIS, Michael L, TANG, Yui S, MILLER, Alisha R, PEARSON, Paul G
Published in Antimicrobial Agents and Chemotherapy (01.04.2004)
Published in Antimicrobial Agents and Chemotherapy (01.04.2004)
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Metabolites of Caspofungin Acetate, a Potent Antifungal Agent, in Human Plasma and Urine
Balani, S K, Xu, X, Arison, B H, Silva, M V, Gries, A, DeLuna, F A, Cui, D, Kari, P H, Ly, T, Hop, C E, Singh, R, Wallace, M A, Dean, D C, Lin, J H, Pearson, P G, Baillie, T A
Published in Drug metabolism and disposition (01.11.2000)
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Published in Drug metabolism and disposition (01.11.2000)
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HEPATIC UPTAKE OF THE NOVEL ANTIFUNGAL AGENT CASPOFUNGIN
SANDHU, Punam, LEE, Wooin, XIN XU, LEAKE, Brenda F, YAMAZAKI, Masayo, STONE, Julie A, LIN, Jiunn H, PEARSON, Paul G, KIM, Richard B
Published in Drug metabolism and disposition (01.05.2005)
Published in Drug metabolism and disposition (01.05.2005)
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Metabolic Activation of a Pyrazinone-Containing Thrombin Inhibitor. Evidence for Novel Biotransformation Involving Pyrazinone Ring Oxidation, Rearrangement, and Covalent Binding to Proteins
Singh, Rominder, Silva Elipe, Maria V, Pearson, Paul G, Arison, Byron H, Wong, Bradley K, White, Rebecca, Yu, Xiao, Burgey, Christopher S, Lin, Jiunn H, Baillie, Thomas A
Published in Chemical research in toxicology (01.02.2003)
Published in Chemical research in toxicology (01.02.2003)
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Enzyme kinetics of cytochrome P450-mediated reactions
Shou, M, Lin, Y, Lu, P, Tang, C, Mei, Q, Cui, D, Tang, W, Ngui, J S, Lin, C C, Singh, R, Wong, B K, Yergey, J A, Lin, J H, Pearson, P G, Baillie, T A, Rodrigues, A D, Rushmore, T H
Published in Current drug metabolism (01.03.2001)
Published in Current drug metabolism (01.03.2001)
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Pharmacokinetics and Interactions of a Novel Antagonist of Chemokine Receptor 5 (CCR5) with Ritonavir in Rats and Monkeys: Role of CYP3A and P-Glycoprotein
Kumar, Sanjeev, Kwei, Gloria Y, Poon, Grace K, Iliff, Susan A, Wang, Yanfeng, Chen, Qing, Franklin, Ronald B, Didolkar, Varsha, Wang, Regina W, Yamazaki, Masayo, Chiu, Shuet-Hing Lee, Lin, Jiunn H, Pearson, Paul G, Baillie, Thomas A
Published in The Journal of pharmacology and experimental therapeutics (01.03.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2003)
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Study of the Fragmentation Mechanism of Protonated 6-Hydroxychlorzoxazone: Application in Simultaneous Analysis of CYP2E1 Activity with Major Human Cytochrome P450s
Anari, M. Reza, Bakhtiar, Ray, Franklin, Ronald B, Pearson, Paul G, Baillie, Thomas A
Published in Analytical chemistry (Washington) (01.02.2003)
Published in Analytical chemistry (Washington) (01.02.2003)
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Biotransformation of tirilazad in human: 1. Cytochrome P450 3A-mediated hydroxylation of tirilazad mesylate in human liver microsomes
Wienkers, L C, Steenwyk, R C, Sanders, P E, Pearson, P G
Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
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Biotransformation of methyl isocyanate in the rat. Evidence for glutathione conjugation as a major pathway of metabolism and implications for isocyanate-mediated toxicities
Slatter, J. Greg, Rashed, Mohamed S, Pearson, Paul G, Han, Deog Hwa, Baillie, Thomas A
Published in Chemical research in toxicology (01.03.1991)
Published in Chemical research in toxicology (01.03.1991)
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Biotransformation of tirilazad in human: 2. Effect of ketoconazole on tirilazad clearance and oral bioavailability
Fleishaker, J C, Pearson, P G, Wienkers, L C, Pearson, L K, Peters, G R
Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
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Hormonal effects on tirilazad clearance in women: assessment of the role of CYP3A
Fleishaker, J C, Pearson, L K, Pearson, P G, Wienkers, L C, Hopkins, N K, Peters, G R
Published in Journal of clinical pharmacology (01.03.1999)
Published in Journal of clinical pharmacology (01.03.1999)
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2-amino-3-(methylamino)-propanoic acid (BMAA) pharmacokinetics and blood-brain barrier permeability in the rat
DUNCAN, M. W, VILLAGRESES, N. E, PEARSON, P. G, WYATT, L, RAPOPORT, S. I, KOPIN, I. J, MARKEY, S. P, SMITH, Q. R
Published in The Journal of pharmacology and experimental therapeutics (01.07.1991)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.1991)
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Biotransformation of Tirilazad in Human: 4. Effect of Finasteride on Tirilazad Clearance and Reduced Metabolite Formation
Fleishaker, J C, Pearson, P G, Wienkers, L C, Pearson, L K, Moore, T A, Peters, G R
Published in The Journal of pharmacology and experimental therapeutics (01.11.1998)
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Published in The Journal of pharmacology and experimental therapeutics (01.11.1998)
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