Recurring and Emerging Ethical Issues in Pragmatic Clinical Trials
Propes, Caleigh, O'Rourke, P Pearl, Morain, Stephanie R
Published in Circulation Cardiovascular quality and outcomes (01.07.2024)
Published in Circulation Cardiovascular quality and outcomes (01.07.2024)
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Framework for development of physician competencies in genomic medicine: report of the Competencies Working Group of the Inter-Society Coordinating Committee for Physician Education in Genomics
Korf, Bruce R., Berry, Anna B., Limson, Melvin, Marian, Ali J., Murray, Michael F., O’Rourke, P. Pearl, Passamani, Eugene R., Relling, Mary V., Tooker, John, Tsongalis, Gregory J., Rodriguez, Laura L.
Published in Genetics in medicine (01.11.2014)
Published in Genetics in medicine (01.11.2014)
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Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood-testis barrier integrity in the seminiferous epithelium
Lie, Pearl P Y, Mruk, Dolores D, Lee, Will M, Cheng, C Yan
Published in The FASEB journal (01.08.2009)
Published in The FASEB journal (01.08.2009)
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Automated seizure detection systems and their effectiveness for each type of seizure
Ulate-Campos, A, Coughlin, F, Lein, M Gaínza, Fernández, I Sánchez, Pearl, P.L, Loddenkemper, T
Published in Seizure (London, England) (01.08.2016)
Published in Seizure (London, England) (01.08.2016)
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Global implementation of genomic medicine: We are not alone
Manolio, Teri A, Abramowicz, Marc, Al-Mulla, Fahd, Anderson, Warwick, Balling, Rudi, Berger, Adam C, Bleyl, Steven, Chakravarti, Aravinda, Chantratita, Wasun, Chisholm, Rex L, Dissanayake, Vajira H W, Dunn, Michael, Dzau, Victor J, Han, Bok-Ghee, Hubbard, Tim, Kolbe, Anne, Korf, Bruce, Kubo, Michiaki, Lasko, Paul, Leego, Erkki, Mahasirimongkol, Surakameth, Majumdar, Partha P, Matthijs, Gert, McLeod, Howard L, Metspalu, Andres, Meulien, Pierre, Miyano, Satoru, Naparstek, Yaakov, O'Rourke, P Pearl, Patrinos, George P, Rehm, Heidi L, Relling, Mary V, Rennert, Gad, Rodriguez, Laura Lyman, Roden, Dan M, Shuldiner, Alan R, Sinha, Sukdeb, Tan, Patrick, Ulfendahl, Mats, Ward, Robyn, Williams, Marc S, Wong, John E L, Green, Eric D, Ginsburg, Geoffrey S
Published in Science translational medicine (03.06.2015)
Published in Science translational medicine (03.06.2015)
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Succinic semialdehyde dehydrogenase deficiency (SSADHD): Pathophysiological complexity and multifactorial trait associations in a rare monogenic disorder of GABA metabolism
Malaspina, P., Roullet, J.-B., Pearl, P.L., Ainslie, G.R., Vogel, K.R., Gibson, K.M.
Published in Neurochemistry international (01.10.2016)
Published in Neurochemistry international (01.10.2016)
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Autophagy, a guardian against neurodegeneration
García-Arencibia, Moisés, Hochfeld, Warren E., Toh, Pearl P.C., Rubinsztein, David C.
Published in Seminars in cell & developmental biology (01.09.2010)
Published in Seminars in cell & developmental biology (01.09.2010)
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Journal Article
Bim Inhibits Autophagy by Recruiting Beclin 1 to Microtubules
Luo, Shouqing, Garcia-Arencibia, Moises, Zhao, Rui, Puri, Claudia, Toh, Pearl P.C., Sadiq, Oana, Rubinsztein, David C.
Published in Molecular cell (10.08.2012)
Published in Molecular cell (10.08.2012)
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Journal Article
Clarifying the Ethics and Oversight of Chimeric Research
Johnston, Josephine, Hyun, Insoo, Neuhaus, Carolyn P., Maschke, Karen J., Marshall, Patricia, Craig, Kaitlynn P., Matthews, Margaret M., Drolet, Kara, Greely, Henry T., Hill, Lori R., Hinterberger, Amy, Hurley, Elisa A., Kesterson, Robert, Kimmelman, Jonathan, King, Nancy M. P., Lopes, Melissa J., O'Rourke, P. Pearl, Parent, Brendan, Peckman, Steven, Piotrowska, Monika, Schwarz, May, Sebo, Jeff, Stodgell, Chris, Streiffer, Robert, Wilkerson, Amy
Published in The Hastings Center report (01.11.2022)
Published in The Hastings Center report (01.11.2022)
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Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons
Lie, Pearl P.Y., Yang, Dun-Sheng, Stavrides, Philip, Goulbourne, Chris N., Zheng, Ping, Mohan, Panaiyur S., Cataldo, Anne M., Nixon, Ralph A.
Published in Cell reports (Cambridge) (27.04.2021)
Published in Cell reports (Cambridge) (27.04.2021)
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Ethical and Practical Guidelines for Reporting Genetic Research Results to Study Participants: Updated Guidelines From a National Heart, Lung, and Blood Institute Working Group
Fabsitz, Richard R, McGuire, Amy, Sharp, Richard R, Puggal, Mona, Beskow, Laura M, Biesecker, Leslie G, Bookman, Ebony, Burke, Wylie, Burchard, Esteban Gonzalez, Church, George, Clayton, Ellen Wright, Eckfeldt, John H, Fernandez, Conrad V, Fisher, Rebecca, Fullerton, Stephanie M, Gabriel, Stacey, Gachupin, Francine, James, Cynthia, Jarvik, Gail P, Kittles, Rick, Leib, Jennifer R, OʼDonnell, Christopher, OʼRourke, P Pearl, Rodriguez, Laura Lyman, Schully, Sheri D, Shuldiner, Alan R, Sze, Rebecca K.F, Thakuria, Joseph V, Wolf, Susan M, Burke, Gregory L
Published in Circulation. Cardiovascular genetics (01.12.2010)
Published in Circulation. Cardiovascular genetics (01.12.2010)
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Journal Article
Return of Genetic Research Results to Participants and Families: IRB Perspectives and Roles
Beskow, Laura M., O'Rourke, P. Pearl
Published in The Journal of law, medicine & ethics (22.09.2015)
Published in The Journal of law, medicine & ethics (22.09.2015)
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Journal Article
Restricted Arp3 expression in the testis prevents blood—testis barrier disruption during junction restructuring at spermatogenesis
Lie, Pearl P. Y., Chan, Apple Y. N., Mruk, Dolores D., Lee, Will M., Cheng, C. Yan, Yanagimachi, Ryuzo
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2010)
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Returning Individual Research Results from Digital Phenotyping in Psychiatry
Shen, Francis X., Baum, Matthew L., Martinez-Martin, Nicole, Miner, Adam S., Abraham, Melissa, Brownstein, Catherine A., Cortez, Nathan, Evans, Barbara J., Germine, Laura T., Glahn, David C., Grady, Christine, Holm, Ingrid A., Hurley, Elisa A., Kimble, Sara, Lázaro-Muñoz, Gabriel, Leary, Kimberlyn, Marks, Mason, Monette, Patrick J., Onnela, Jukka-Pekka, O'Rourke, P. Pearl, Rauch, Scott L., Shachar, Carmel, Sen, Srijan, Vahia, Ipsit, Vassy, Jason L., Baker, Justin T., Bierer, Barbara E., Silverman, Benjamin C.
Published in American journal of bioethics (01.02.2024)
Published in American journal of bioethics (01.02.2024)
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Decreased GABA-A binding on FMZ-PET in succinic semialdehyde dehydrogenase deficiency
Pearl, P L, Gibson, K M, Quezado, Z, Dustin, I, Taylor, J, Trzcinski, S, Schreiber, J, Forester, K, Reeves-Tyer, P, Liew, C, Shamim, S, Herscovitch, P, Carson, R, Butman, J, Jakobs, C, Theodore, W
Published in Neurology (11.08.2009)
Published in Neurology (11.08.2009)
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