Pharmacophore Identification and Structure–Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of Trypanosoma brucei
Ferrins, Lori, Diaz, Rosario, Cordon-Obras, Carlos, Rojas-Barros, Domingo, Quotadamo, Antonio, Oehme, Daniel P., Ceballos-Pérez, Gloria, Swaminathan, Uma, Pérez-Moreno, Guiomar, Bosch-Navarrete, Cristina, García-Hernández, Raquel, Gomez-Liñan, Claudia, Saura, Andreu, Ruiz-Perez, Luis Miguel, Gamarro, Francisco, Martinez-Martinez, Maria Santos, Manzano, Pilar, González-Pacanowska, Dolores, Navarro, Miguel, Pollastri, Michael P.
Published in Journal of medicinal chemistry (22.08.2024)
Published in Journal of medicinal chemistry (22.08.2024)
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Journal Article
Strasseriolides A–D, A Family of Antiplasmodial Macrolides Isolated from the Fungus Strasseria geniculata CF-247251
Annang, Frederick, Pérez-Moreno, Guiomar, González-Menéndez, Víctor, Lacret, Rodney, Pérez-Victoria, Ignacio, Martín, Jesús, Cantizani, Juan, de Pedro, Nuria, Choquesillo-Lazarte, Duane, Ruiz-Pérez, Luis M, González-Pacanowska, Dolores, Genilloud, Olga, Vicente, Francisca, Reyes, Fernando
Published in Organic letters (04.09.2020)
Published in Organic letters (04.09.2020)
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Journal Article
MDN-0104, an Antiplasmodial Betaine Lipid from Heterospora chenopodii
Martín, Jesús, Crespo, Gloria, González-Menéndez, Víctor, Pérez-Moreno, Guiomar, Sánchez-Carrasco, Paula, Pérez-Victoria, Ignacio, Ruiz-Pérez, Luis M, González-Pacanowska, Dolores, Vicente, Francisca, Genilloud, Olga, Bills, Gerald F, Reyes, Fernando
Published in Journal of natural products (Washington, D.C.) (26.09.2014)
Published in Journal of natural products (Washington, D.C.) (26.09.2014)
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Journal Article
Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi
Bosch-Navarrete, Cristina, Pérez-Moreno, Guiomar, Annang, Frederick, Diaz-Gonzalez, Rosario, García-Hernández, Raquel, Rocha, Hedy, Gamarro, Francisco, Cordón-Obras, Carlos, Navarro, Miguel, Rodriguez, Ana, Genilloud, Olga, Reyes, Fernando, Vicente, Francisca, Ruiz-Pérez, Luis M, González-Pacanowska, Dolores
Published in PLoS neglected tropical diseases (01.09.2023)
Published in PLoS neglected tropical diseases (01.09.2023)
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Journal Article
Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5‑b]pyridazines for the Treatment of Human African Trypanosomiasis
Tear, Westley F, Bag, Seema, Diaz-Gonzalez, Rosario, Ceballos-Pérez, Gloria, Rojas-Barros, Domingo I, Cordon-Obras, Carlos, Pérez-Moreno, Guiomar, García-Hernández, Raquel, Martinez-Martinez, Maria Santos, Ruiz-Perez, Luis Miguel, Gamarro, Francisco, Gonzalez Pacanowska, Dolores, Caffrey, Conor R, Ferrins, Lori, Manzano, Pilar, Navarro, Miguel, Pollastri, Michael P
Published in Journal of medicinal chemistry (23.01.2020)
Published in Journal of medicinal chemistry (23.01.2020)
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Journal Article
Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis
Klug, Dana M, Mavrogiannaki, Eftychia M, Forbes, Katherine C, Silva, Lisseth, Diaz-Gonzalez, Rosario, Pérez-Moreno, Guiomar, Ceballos-Pérez, Gloria, Garcia-Hernández, Raquel, Bosch-Navarrete, Cristina, Cordón-Obras, Carlos, Gómez-Liñán, Claudia, Saura, Andreu, Momper, Jeremiah D, Martinez-Martinez, Maria Santos, Manzano, Pilar, Syed, Ali, El-Sakkary, Nelly, Caffrey, Conor R, Gamarro, Francisco, Ruiz-Perez, Luis Miguel, Gonzalez Pacanowska, Dolores, Ferrins, Lori, Navarro, Miguel, Pollastri, Michael P
Published in Journal of medicinal chemistry (08.07.2021)
Published in Journal of medicinal chemistry (08.07.2021)
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Journal Article
Bioactivities and Extract Dereplication of Actinomycetales Isolated From Marine Sponges
Santos, José D, Vitorino, Inês, De la Cruz, Mercedes, Díaz, Caridad, Cautain, Bastien, Annang, Frederick, Pérez-Moreno, Guiomar, Gonzalez Martinez, Ignacio, Tormo, Jose R, Martín, Jesús M, Urbatzka, Ralph, Vicente, Francisca M, Lage, Olga M
Published in Frontiers in microbiology (09.04.2019)
Published in Frontiers in microbiology (09.04.2019)
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Journal Article
MDN-0185, an Antiplasmodial Polycyclic Xanthone Isolated from Micromonospora sp. CA-256353
Annang, Frederick, Pérez-Victoria, Ignacio, Pérez-Moreno, Guiomar, Domingo, Elizabeth, González, Ignacio, Tormo, José Rubén, Martín, Jesús, Ruiz-Pérez, Luis M, Genilloud, Olga, González-Pacanowska, Dolores, Vicente, Francisca, Reyes, Fernando
Published in Journal of natural products (Washington, D.C.) (27.07.2018)
Published in Journal of natural products (Washington, D.C.) (27.07.2018)
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Journal Article
Preclinical evaluation of strasseriolides A–D, potent antiplasmodial macrolides isolated from Strasseria geniculata CF-247,251
Annang, Frederick, Pérez-Moreno, Guiomar, Díaz, Caridad, González-Menéndez, Victor, de Pedro Montejo, Nuria, del Palacio, José Pérez, Sánchez, Paula, Tanghe, Scott, Rodriguez, Ana, Pérez-Victoria, Ignacio, Cantizani, Juan, Ruiz-Pérez, Luis M, Genilloud, Olga, Reyes, Fernando, Vicente, Francisca, González-Pacanowska, Dolores
Published in Malaria journal (05.12.2021)
Published in Malaria journal (05.12.2021)
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Journal Article
Discovery of New Compounds Active against Plasmodium falciparum by High Throughput Screening of Microbial Natural Products
Pérez-Moreno, Guiomar, Cantizani, Juan, Sánchez-Carrasco, Paula, Ruiz-Pérez, Luis Miguel, Martín, Jesús, El Aouad, Noureddine, Pérez-Victoria, Ignacio, Tormo, José Rubén, González-Menendez, Víctor, González, Ignacio, de Pedro, Nuria, Reyes, Fernando, Genilloud, Olga, Vicente, Francisca, González-Pacanowska, Dolores
Published in PloS one (06.01.2016)
Published in PloS one (06.01.2016)
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Journal Article
Validation of Plasmodium falciparum dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity
Pérez-Moreno, Guiomar, Sánchez-Carrasco, Paula, Ruiz-Pérez, Luis Miguel, Johansson, Nils Gunnar, Müller, Sylke, Baragaña, Beatriz, Hampton, Shahienaz Emma, Gilbert, Ian Hugh, Kaiser, Marcel, Sarkar, Sandipan, Pandurangan, Thiyagamurthy, Kumar, Vijeesh, González-Pacanowska, Dolores
Published in Malaria journal (03.12.2019)
Published in Malaria journal (03.12.2019)
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Journal Article
Establishment of a screening platform based on human coronavirus OC43 for the identification of microbial natural products with antiviral activity
Martínez-Arribas, Blanca, Annang, Frederick, Díaz-González, Rosario, Pérez-Moreno, Guiomar, Martín, Jesús, Mackenzie, Thomas A, Castillo, Francisco, Reyes, Fernando, Genilloud, Olga, Ruiz-Pérez, Luis Miguel, Vicente, Francisca, Ramos, María C, González-Pacanowska, Dolores
Published in Microbiology spectrum (11.01.2024)
Published in Microbiology spectrum (11.01.2024)
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Journal Article
Antiparasitic Activities of Compounds Isolated from Aspergillus fumigatus Strain Discovered in Northcentral Nigeria
Diyaolu, Oluwatofunmilayo A, Preet, Gagan, Fagbemi, Adeshola A, Annang, Frederick, Pérez-Moreno, Guiomar, Bosch-Navarrete, Cristina, Adebisi, Olusoji O, Oluwabusola, Emmanuel T, Milne, Bruce F, Jaspars, Marcel, Ebel, Rainer
Published in Antibiotics (Basel) (06.01.2023)
Published in Antibiotics (Basel) (06.01.2023)
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Journal Article
Antiparasitic Meroterpenoids Isolated from Memnoniella dichroa CF-080171
Annang, Frederick Boye, Pérez-Moreno, Guiomar, Bosch-Navarrete, Cristina, González-Menéndez, Victor, Martín, Jesús, Mackenzie, Thomas A, Ramos, Maria C, Ruiz-Pérez, Luis M, Genilloud, Olga, González-Pacanowska, Dolores, Vicente, Francisca, Reyes, Fernando
Published in Pharmaceutics (02.02.2023)
Published in Pharmaceutics (02.02.2023)
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Journal Article
New Compounds with Bioisosteric Replacement of Classic Choline Kinase Inhibitors Show Potent Antiplasmodial Activity
Aguilar-Troyano, Francisco José, Torretta, Archimede, Rubbini, Gianluca, Fasiolo, Alberto, Luque-Navarro, Pilar María, Carrasco-Jimenez, María Paz, Pérez-Moreno, Guiomar, Bosch-Navarrete, Cristina, González-Pacanowska, Dolores, Parisini, Emilio, Lopez-Cara, Luisa Carlota
Published in Pharmaceutics (02.11.2021)
Published in Pharmaceutics (02.11.2021)
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Journal Article
Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents
Klug, Dana M, Diaz-Gonzalez, Rosario, Pérez-Moreno, Guiomar, Ceballos-Pérez, Gloria, García-Hernández, Raquel, Gomez-Pérez, Veronica, Ruiz-Pérez, Luis Miguel, Rojas-Barros, Domingo I, Gamarro, Francisco, González-Pacanowska, Dolores, Martínez-Martínez, María S, Manzano, Pilar, Ferrins, Lori, Caffrey, Conor R, Navarro, Miguel, Pollastri, Michael P
Published in PLoS neglected tropical diseases (01.02.2019)
Published in PLoS neglected tropical diseases (01.02.2019)
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Journal Article
Cytotoxycity and antiplasmodial activity of phenolic derivatives from Albizia zygia (DC.) J.F. Macbr. (Mimosaceae)
Koagne, Romeol Romain, Annang, Frederick, Cautain, Bastien, Martín, Jesús, Pérez-Moreno, Guiomar, Bitchagno, Gabin Thierry M, González-Pacanowska, Dolores, Vicente, Francisca, Simo, Ingrid Konga, Reyes, Fernando, Tane, Pierre
Published in BMC complementary and alternative medicine (15.01.2020)
Published in BMC complementary and alternative medicine (15.01.2020)
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Journal Article
Lasionectrin, a Naphthopyrone from a Lasionectria sp
El Aouad, Noureddine, Pérez-Moreno, Guiomar, Sánchez, Paula, Cantizani, Juan, Ortiz-López, Francisco Javier, Martín, Jesús, González-Menéndez, Víctor, Ruiz-Pérez, Luis M, González-Pacanowska, Dolores, Vicente, Francisca, Bills, Gerald, Reyes, Fernando
Published in Journal of natural products (Washington, D.C.) (22.06.2012)
Published in Journal of natural products (Washington, D.C.) (22.06.2012)
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Journal Article
Collective and Diverted Total Synthesis of the Strasseriolides: A Family of Macrolides Endowed with Potent Antiplasmodial and Antitrypanosomal Activity
Isak, Daniel, Schwartz, Leyah A., Schulthoff, Saskia, Pérez‐Moreno, Guiomar, Bosch‐Navarrete, Cristina, González‐Pacanowska, Dolores, Fürstner, Alois
Published in Angewandte Chemie International Edition (02.09.2024)
Published in Angewandte Chemie International Edition (02.09.2024)
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Journal Article
Antiparasitic Activity of Bromotyrosine Alkaloids and New Analogues Isolated from the Fijian Marine Sponge Aplysinella rhax
Oluwabusola, Emmanuel T., Tabudravu, Jioji N., Al Maqbali, Khalid S., Annang, Frederick, Pérez‐Moreno, Guiomar, Reyes, Fernando, Jaspars, Marcel
Published in Chemistry & biodiversity (01.10.2020)
Published in Chemistry & biodiversity (01.10.2020)
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Journal Article