Functional Amyloids: The Biomaterials of Tomorrow?
Peña‐Díaz, Samuel, Olsen, William Pallisgaard, Wang, Huabing, Otzen, Daniel E.
Published in Advanced materials (Weinheim) (01.05.2024)
Published in Advanced materials (Weinheim) (01.05.2024)
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Journal Article
CsgA gatekeeper residues control nucleation but not stability of functional amyloid
Olsen, William P., Courtade, Gaston, Peña‐Díaz, Samuel, Nagaraj, Madhu, Sønderby, Thorbjørn V., Mulder, Frans A. A., Malle, Mette G., Otzen, Daniel E.
Published in Protein science (01.10.2024)
Published in Protein science (01.10.2024)
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Journal Article
Functional Amyloids: The Biomaterials of Tomorrow? (Adv. Mater. 18/2024)
Peña‐Díaz, Samuel, Olsen, William Pallisgaard, Wang, Huabing, Otzen, Daniel E.
Published in Advanced materials (Weinheim) (01.05.2024)
Published in Advanced materials (Weinheim) (01.05.2024)
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Journal Article
α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity
Santos, Jaime, Gracia, Pablo, Navarro, Susanna, Peña-Díaz, Samuel, Pujols, Jordi, Cremades, Nunilo, Pallarès, Irantzu, Ventura, Salvador
Published in Nature communications (18.06.2021)
Published in Nature communications (18.06.2021)
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Journal Article
High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors
Pujols, Jordi, Peña-Díaz, Samuel, Conde-Giménez, María, Pinheiro, Francisca, Navarro, Susanna, Sancho, Javier, Ventura, Salvador
Published in International journal of molecular sciences (02.03.2017)
Published in International journal of molecular sciences (02.03.2017)
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Journal Article
Discovery of Neuroprotective Agents Based on a 5‑(4-Pyridinyl)-1,2,4-triazole Scaffold
Gitto, Rosaria, Vittorio, Serena, Bucolo, Federica, Peña-Díaz, Samuel, Siracusa, Rosalba, Cuzzocrea, Salvatore, Ventura, Salvador, Di Paola, Rosanna, De Luca, Laura
Published in ACS chemical neuroscience (02.03.2022)
Published in ACS chemical neuroscience (02.03.2022)
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Journal Article
Ligand-Based Discovery of a Small Molecule as Inhibitor of α-Synuclein Amyloid Formation
De Luca, Laura, Vittorio, Serena, Peña-Díaz, Samuel, Pitasi, Giovanna, Fornt-Suñé, Marc, Bucolo, Federica, Ventura, Salvador, Gitto, Rosaria
Published in International journal of molecular sciences (27.11.2022)
Published in International journal of molecular sciences (27.11.2022)
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Journal Article
Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson's disease
Vittorio, Serena, Adornato, Ilenia, Gitto, Rosaria, Peña-Díaz, Samuel, Ventura, Salvador, De Luca, Laura
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
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Journal Article
Mining and engineering activity in catalytic amyloids
Peña-Díaz, Samuel, Ferreira, Pedro, Ramos, Maria João, Otzen, Daniel E
Published in Methods in enzymology (2024)
Published in Methods in enzymology (2024)
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Journal Article
Small molecules to target tau amyloid aggregation
Manglano-Artuñedo, Zoe, Peña-Díaz, Samuel, Ventura, Salvador
Published in Neural regeneration research (01.03.2024)
Published in Neural regeneration research (01.03.2024)
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Journal Article
ZPD-2, a Small Compound That Inhibits α-Synuclein Amyloid Aggregation and Its Seeded Polymerization
Peña-Díaz, Samuel, Pujols, Jordi, Conde-Giménez, María, Čarija, Anita, Dalfo, Esther, García, Jesús, Navarro, Susanna, Pinheiro, Francisca, Santos, Jaime, Salvatella, Xavier, Sancho, Javier, Ventura, Salvador
Published in Frontiers in molecular neuroscience (17.12.2019)
Published in Frontiers in molecular neuroscience (17.12.2019)
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Journal Article
Small molecules to prevent the neurodegeneration caused by α-synuclein aggregation
Pena-Diaz, Samuel, Pujols, Jordi, Ventura, Salvador
Published in Neural regeneration research (01.12.2020)
Published in Neural regeneration research (01.12.2020)
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Journal Article
Inhibition of α-Synuclein Aggregation and Mature Fibril Disassembling With a Minimalistic Compound, ZPDm
Peña-Díaz, Samuel, Pujols, Jordi, Pinheiro, Francisca, Santos, Jaime, Pallarés, Irantzu, Navarro, Susanna, Conde-Gimenez, María, García, Jesús, Salvatella, Xavier, Dalfó, Esther, Sancho, Javier, Ventura, Salvador
Published in Frontiers in bioengineering and biotechnology (16.10.2020)
Published in Frontiers in bioengineering and biotechnology (16.10.2020)
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Journal Article
Chemical Chaperones as Novel Drugs for Parkinson’s Disease
Pujols, Jordi, Peña-Díaz, Samuel, Pallarès, Irantzu, Ventura, Salvador
Published in Trends in molecular medicine (01.04.2020)
Published in Trends in molecular medicine (01.04.2020)
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Journal Article
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons
Pujols, Jordi, Peña-Díaz, Samuel, Lázaro, Diana F., Peccati, Francesca, Pinheiro, Francisca, González, Danilo, Carija, Anita, Navarro, Susanna, Conde-Giménez, María, García, Jesús, Guardiola, Salvador, Giralt, Ernest, Salvatella, Xavier, Sancho, Javier, Sodupe, Mariona, Outeiro, Tiago Fleming, Dalfó, Esther, Ventura, Salvador
Published in Proceedings of the National Academy of Sciences - PNAS (09.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (09.10.2018)
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Journal Article
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains
Peña-Díaz, Samuel, Pujols, Jordi, Vasili, Eftychia, Pinheiro, Francisca, Santos, Jaime, Manglano-Artuñedo, Zoe, Outeiro, Tiago F., Ventura, Salvador
Published in The Journal of biological chemistry (01.05.2022)
Published in The Journal of biological chemistry (01.05.2022)
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Journal Article