Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation
Pasch, Cheri A, Favreau, Peter F, Yueh, Alexander E, Babiarz, Christopher P, Gillette, Amani A, Sharick, Joe T, Karim, Mohammad Rezaul, Nickel, Kwangok P, DeZeeuw, Alyssa K, Sprackling, Carley M, Emmerich, Philip B, DeStefanis, Rebecca A, Pitera, Rosabella T, Payne, Susan N, Korkos, Demetra P, Clipson, Linda, Walsh, Christine M, Miller, Devon, Carchman, Evie H, Burkard, Mark E, Lemmon, Kayla K, Matkowskyj, Kristina A, Newton, Michael A, Ong, Irene M, Bassetti, Michael F, Kimple, Randall J, Skala, Melissa C, Deming, Dustin A
Published in Clinical cancer research (01.09.2019)
Published in Clinical cancer research (01.09.2019)
Get full text
Journal Article
Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K
Yueh, Alexander E, Payne, Susan N, Leystra, Alyssa A, Van De Hey, Dana R, Foley, Tyler M, Pasch, Cheri A, Clipson, Linda, Matkowskyj, Kristina A, Deming, Dustin A
Published in PloS one (10.02.2016)
Published in PloS one (10.02.2016)
Get full text
Journal Article
Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations
Foley, Tyler M, Payne, Susan N, Pasch, Cheri A, Yueh, Alex E, Van De Hey, Dana R, Korkos, Demetra P, Clipson, Linda, Maher, Molly E, Matkowskyj, Kristina A, Newton, Michael A, Deming, Dustin A
Published in Molecular cancer research (09.02.2017)
Published in Molecular cancer research (09.02.2017)
Get full text
Journal Article
Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations
Foley, Tyler M, Payne, Susan N, Pasch, Cheri A, Yueh, Alex E, Van De Hey Dana R, Korkos, Demetra P, Clipson, Linda, Maher, Molly E, Matkowskyj, Kristina A, Newton, Michael A, Deming, Dustin A
Published in Molecular cancer research (01.03.2017)
Published in Molecular cancer research (01.03.2017)
Get full text
Journal Article
MTORC1/2 Inhibition as a Therapeutic Strategy for PIK3CA Mutant Cancers
Fricke, Stephanie L, Payne, Susan N, Favreau, Peter F, Kratz, Jeremy D, Pasch, Cheri A, Foley, Tyler M, Yueh, Alexander E, Van De Hey, Dana R, Depke, Mitchell G, Korkos, Demetra P, Sha, Gioia Chengcheng, DeStefanis, Rebecca A, Clipson, Linda, Burkard, Mark E, Lemmon, Kayla K, Parsons, Benjamin M, Kenny, Paraic A, Matkowskyj, Kristina A, Newton, Michael A, Skala, Melissa C, Deming, Dustin A
Published in Molecular cancer therapeutics (01.02.2019)
Published in Molecular cancer therapeutics (01.02.2019)
Get full text
Journal Article
Colon Tumors with the Simultaneous Induction of Driver Mutations in APC, KRAS, and PIK3CA Still Progress through the Adenoma-to-carcinoma Sequence
Hadac, Jamie N, Leystra, Alyssa A, Paul Olson, Terrah J, Maher, Molly E, Payne, Susan N, Yueh, Alexander E, Schwartz, Alexander R, Albrecht, Dawn M, Clipson, Linda, Pasch, Cheri A, Matkowskyj, Kristina A, Halberg, Richard B, Deming, Dustin A
Published in Cancer prevention research (Philadelphia, Pa.) (01.10.2015)
Published in Cancer prevention research (Philadelphia, Pa.) (01.10.2015)
Get full text
Journal Article
Abstract 75: BCL-xL inhibition enhances therapeutic response of MTORC1/2 inhibition and induction of apoptosis in PIK3CA mutant colorectal cancer
DeStefanis, Rebecca A., DeZeeuw, Alyssa, Sha, Gioia, Payne, Susan N., Babiarz, Christopher P., Miller, Devon, Korkos, Demetra K., Pasch, Cheri A., Clipson, Linda, Matkowskyj, Kristina, Deming, Dustin A.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Get full text
Journal Article
Abstract 304: Dual PI3K/BCL-2 family inhibition in colorectal cancers with Apc and Pik3ca mutations
Miller, Devon D., Babiarz, Christopher P., Payne, Susan N., Pasch, Cheri A., Clipson, Linda, Matkowskyj, Kristina A., Deming, Dustin A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article
Abstract 5019: Everolimus in combination with ABT263 in patient-derived organotypic neuroendocrine tumor spheroids
Babiarz, Christopher P., Gillette, Amani, Depke, Mitchell G., Pasch, Cheri A., Payne, Susan N., Sprackling, Carley M., Clipson, Linda, Matkowskyj, Kristina A., Skala, Melissa C., Deming, Dustin A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article
Abstract 1904: Versican production is driven by both epithelial and stromal cells in pancreatic cancer
Rainiero, Hanna R., Emmerich, Philip B., Sievers, Chelsie K., Maloney, Connor J., Pitera, Rosabella T., Payne, Susan N., Depke, Mitchell G., Pasch, Cheri A., Clipson, Linda, Johnson, Jillian K., Matkowskyj, Kristina A., Asimakopoulos, Fotis, Deming, Dustin A.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Abstract 1128: MTORC1/2 and HDAC1/2 inhibition promote tumor response through inhibition of MYC
DeStefanis, Rebecca A., Olson, Autumn M., DeZeeuw, Alyssa K., Payne, Susan N., Pasch, Cheri A., Clipson, Linda, Deming, Dustin A.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
Abstract 3721: MTORC1/2 and HDAC1/2 inhibition as therapy for colorectal cancer with PIK3CA mutation
Olson, Autumn M., DeStefanis, Rebecca A., DeZeeuw, Alyssa K., Payne, Susan N., Pasch, Cheri A., Clipson, Linda, Deming, Dustin A.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
Abstract 2673: Combined inhibition of PI3K and HDAC1/2 as a novel treatment strategy for RAS/RAF wildtype colorectal cancer in a patient derived organoid model
DeZeeuw, Alyssa K., DeStefanis, Rebecca A., Payne, Susan N., Olson, Autumn M., Pasch, Cheri A., Clipson, Linda, Deming, Dustin A.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
Abstract B27: MTORC1/2 inhibition as a treatment strategy for PIK3CA mutant colorectal cancer
DeStefanis, Rebecca A., Payne, Susan N., Miller, Devon, Pasch, Cheri A., Babiarz, Christopher, DeZeeuw, Alyssa, Fricke, Stephanie L., Sprackling, Carley, Yueh, Alexander E., Korkos, Demetra P., Van De Hey, Dana R., Sha, Gioia, Greane, Aurora, Kratz, Jeremy D., Clipson, Linda, Matkowskyj, Kristina A., Newton, Michael A., Deming, Dustin A.
Published in Molecular cancer research (01.10.2020)
Published in Molecular cancer research (01.10.2020)
Get full text
Journal Article
Abstract 3146: Versican proteolysis: A novel immunostimulatory component of CD8+ T cell responses to colorectal cancer
Emmerich, Philip B., Payne, Susan N., Maloney, Connor J., Pitera, Rosabella T., Rainiero, Hanna, Sha, Gioia, Papadas, Athanasios T., Pagenkopf, Adam C., Bassetti, Michael F., Matkowskyj, Kristina A., Asimakopoulos, Fotis, Deming, Dustin A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article
Abstract 2936: MTORC1/2 inhibition in combination with BCL-2/BCL-xL inhibition in APC and PIK3CA mutant colorectal cancer
Fricke, Stephanie L., Payne, Susan N., Pasch, Cheri A., Korkos, Demetra P., Sha, Gioia, Yueh, Alex E., Babiarz, Christopher, Clipson, Linda, Matkowskyj, Kristina A., Newton, Michael A., Deming, Dustin A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article
Abstract 5011: Patient-derived organotypic cancer spheroids (PDOCS) as predictive models for the treatment of cancer in a clinically meaningful time frame
Pasch, Cheri A., Favreau, Peter F., Yueh, Alex E., Nickel, Kwang P., Babiarz, Christopher P., Emmerich, Philip B., Pitera, Rosabella T., Payne, Susan N., Korkos, Demetra P., Sharick, Joseph T., Sprackling, Carley M., Clipson, Linda, Matkowskyj, Kristina A., Newton, Michael A., Skala, Melissa C., Bassetti, Michael F., Kimple, Randall J., Deming, Dustin A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article