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The pediatric preclinical testing program: Description of models and early testing results
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Modeling and targeting of erythroleukemia by hematopoietic genome editing
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PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia
Dang, Jinjun, Wei, Lei, de Ridder, Jeroen, Su, Xiaoping, Rust, Alistair G., Roberts, Kathryn G., Payne-Turner, Debbie, Cheng, Jinjun, Ma, Jing, Qu, Chunxu, Wu, Gang, Song, Guangchun, Huether, Robert G., Schulman, Brenda, Janke, Laura, Zhang, Jinghui, Downing, James R., van der Weyden, Louise, Adams, David J., Mullighan, Charles G.
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Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia
Waanders, Esmé, Gu, Zhaohui, Dobson, Stephanie M, Antić, Željko, Crawford, Jeremy Chase, Ma, Xiaotu, Edmonson, Michael N, Payne-Turner, Debbie, van de Vorst, Maartje, Jongmans, Marjolijn C J, McGuire, Irina, Zhou, Xin, Wang, Jian, Shi, Lei, Pounds, Stanley, Pei, Deqing, Cheng, Cheng, Song, Guangchun, Fan, Yiping, Shao, Ying, Rusch, Michael, McCastlain, Kelly, Yu, Jiangyan, van Boxtel, Ruben, Blokzijl, Francis, Iacobucci, Ilaria, Roberts, Kathryn G, Wen, Ji, Wu, Gang, Ma, Jing, Easton, John, Neale, Geoffrey, Olsen, Scott R, Nichols, Kim E, Pui, Ching-Hon, Zhang, Jinghui, Evans, William E, Relling, Mary V, Yang, Jun J, Thomas, Paul G, Dick, John E, Kuiper, Roland P, Mullighan, Charles G
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Payton, Antony, Payne, Debbie, Mankhambo, Limangeni A, Banda, Daniel L, Hart, C Anthony, Ollier, William Er, Carrol, Enitan D
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Andersson, Anna K, Ma, Jing, Wang, Jianmin, Chen, Xiang, Gedman, Amanda Larson, Dang, Jinjun, Nakitandwe, Joy, Holmfeldt, Linda, Parker, Matthew, Easton, John, Huether, Robert, Kriwacki, Richard, Rusch, Michael, Wu, Gang, Li, Yongjin, Mulder, Heather, Raimondi, Susana, Pounds, Stanley, Kang, Guolian, Shi, Lei, Becksfort, Jared, Gupta, Pankaj, Payne-Turner, Debbie, Vadodaria, Bhavin, Boggs, Kristy, Yergeau, Donald, Manne, Jayanthi, Song, Guangchun, Edmonson, Michael, Nagahawatte, Panduka, Wei, Lei, Cheng, Cheng, Pei, Deqing, Sutton, Rosemary, Venn, Nicola C, Chetcuti, Albert, Rush, Amanda, Catchpoole, Daniel, Heldrup, Jesper, Fioretos, Thoas, Lu, Charles, Ding, Li, Pui, Ching-Hon, Shurtleff, Sheila, Mullighan, Charles G, Mardis, Elaine R, Wilson, Richard K, Gruber, Tanja A, Zhang, Jinghui, Downing, James R
Published in Nature genetics (01.04.2015)
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Deregulation of DUX4 and ERG in acute lymphoblastic leukemia
Zhang, Jinghui, McCastlain, Kelly, Yoshihara, Hiroki, Xu, Beisi, Chang, Yunchao, Churchman, Michelle L, Wu, Gang, Li, Yongjin, Wei, Lei, Iacobucci, Ilaria, Liu, Yu, Qu, Chunxu, Wen, Ji, Edmonson, Michael, Payne-Turner, Debbie, Kaufmann, Kerstin B, Takayanagi, Shin-ichiro, Wienholds, Erno, Waanders, Esmé, Ntziachristos, Panagiotis, Bakogianni, Sofia, Wang, Jingjing, Aifantis, Iannis, Roberts, Kathryn G, Ma, Jing, Song, Guangchun, Easton, John, Mulder, Heather L, Chen, Xiang, Newman, Scott, Ma, Xiaotu, Rusch, Michael, Gupta, Pankaj, Boggs, Kristy, Vadodaria, Bhavin, Dalton, James, Liu, Yanling, Valentine, Marcus L, Ding, Li, Lu, Charles, Fulton, Robert S, Fulton, Lucinda, Tabib, Yashodhan, Ochoa, Kerri, Devidas, Meenakshi, Pei, Deqing, Cheng, Cheng, Yang, Jun, Evans, William E, Relling, Mary V, Pui, Ching-Hon, Jeha, Sima, Harvey, Richard C, Chen, I-Ming L, Willman, Cheryl L, Marcucci, Guido, Bloomfield, Clara D, Kohlschmidt, Jessica, Mrózek, Krzysztof, Paietta, Elisabeth, Tallman, Martin S, Stock, Wendy, Foster, Matthew C, Racevskis, Janis, Rowe, Jacob M, Luger, Selina, Kornblau, Steven M, Shurtleff, Sheila A, Raimondi, Susana C, Mardis, Elaine R, Wilson, Richard K, Dick, John E, Hunger, Stephen P, Loh, Mignon L, Downing, James R, Mullighan, Charles G
Published in Nature genetics (01.12.2016)
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Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia
Gu, Zhaohui, Churchman, Michelle, Roberts, Kathryn, Li, Yongjin, Liu, Yu, Harvey, Richard C., McCastlain, Kelly, Reshmi, Shalini C., Payne-Turner, Debbie, Iacobucci, Ilaria, Shao, Ying, Chen, I-Ming, Valentine, Marcus, Pei, Deqing, Mungall, Karen L., Mungall, Andrew J., Ma, Yussanne, Moore, Richard, Marra, Marco, Stonerock, Eileen, Gastier-Foster, Julie M., Devidas, Meenakshi, Dai, Yunfeng, Wood, Brent, Borowitz, Michael, Larsen, Eric E., Maloney, Kelly, Mattano Jr, Leonard A., Angiolillo, Anne, Salzer, Wanda L., Burke, Michael J., Gianni, Francesca, Spinelli, Orietta, Radich, Jerald P., Minden, Mark D., Moorman, Anthony V., Patel, Bella, Fielding, Adele K., Rowe, Jacob M., Luger, Selina M., Bhatia, Ravi, Aldoss, Ibrahim, Forman, Stephen J., Kohlschmidt, Jessica, Mrózek, Krzysztof, Marcucci, Guido, Bloomfield, Clara D., Stock, Wendy, Kornblau, Steven, Kantarjian, Hagop M., Konopleva, Marina, Paietta, Elisabeth, Willman, Cheryl L., L. Loh, Mignon, P. Hunger, Stephen, Mullighan, Charles G.
Published in Nature communications (08.11.2016)
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Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation
Östling, Jörgen, Ax, Elisabeth, Calvén, Jenny, Thörn, Kristofer, Israelsson, Elisabeth, Öberg, Lisa, Wilson, Susan J., Ward, Jonathan A., Chauhan, Anoop, Sousa, Ana R., De Meulder, Bertrand, Baribaud, Frédéric, Sterk, Peter J., Guo, Yike, Dahlen, Barbro, Chanez, Pascal, Shaw, Dominick E., Krug, Norbert, Hohlfeld, Jens M., Sandström, Thomas, James, Anna, Hinks, Timothy S.C., Howarth, Peter H., Vaarala, Outi, van Geest, Marleen, Olsson, Henric, Ahmed, H., Auffray, C., Bakke, P., Bansal, A.T., Bates, S., Bel, E.H., Bigler, J., Boedigheimer, M.J., Bønnelykke, K., Brandsma, J., Bucchioni, E., Bush, A., Caruso, M., Chaiboonchoe, A., Chanez, P., Chung, F.K., Corfield, J., D'Amico, A., De Meulder, B., Djukanovic, R., Fichtner, K., Fleming, L.J., Formaggio, E., Frey, U., Goss, V., Guo, Y., Hashimoto, S., Haughney, J., Hekking, P.W., Higenbottam, T., Hohlfeld, J.M., Holweg, C., Horváth, I., James, A.J., Knowles, R., Loza, M.J., Manta, A., Matthews, J.G., Mazein, A., Meiser, A., Middelveld, R.J.M., Miralpeix, M., Montuschi, P., Murray, C.S., Myles, D., Pahus, L., Pandis, I., Pavlidis, S., Postle, A., Powel, P., Praticò, G., Riley, J., Roberts, G., Rowe, A., Sandström, T., Schofield, J.P.R., Selby, A., Shaw, D.E., Sigmund, R., Singer, F., Skipp, P.J., Sousa, A.R., Sterk, P.J., Sun, K., Thornton, B., van Aalderen, W.M., van Geest, M., Vestbo, J., Vissing, N.H., Wagener, A.H., Wagers, S.S., Weiszhart, Z., Wheelock, C.E., Wilson, S.J.
Published in Journal of allergy and clinical immunology (01.02.2019)
Published in Journal of allergy and clinical immunology (01.02.2019)
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The genomic landscape of hypodiploid acute lymphoblastic leukemia
Holmfeldt, Linda, Wei, Lei, Diaz-Flores, Ernesto, Walsh, Michael, Zhang, Jinghui, Ding, Li, Payne-Turner, Debbie, Churchman, Michelle, Andersson, Anna, Chen, Shann-Ching, McCastlain, Kelly, Becksfort, Jared, Ma, Jing, Wu, Gang, Patel, Samir N, Heatley, Susan L, Phillips, Letha A, Song, Guangchun, Easton, John, Parker, Matthew, Chen, Xiang, Rusch, Michael, Boggs, Kristy, Vadodaria, Bhavin, Hedlund, Erin, Drenberg, Christina, Baker, Sharyn, Pei, Deqing, Cheng, Cheng, Huether, Robert, Lu, Charles, Fulton, Robert S, Fulton, Lucinda L, Tabib, Yashodhan, Dooling, David J, Ochoa, Kerri, Minden, Mark, Lewis, Ian D, To, L Bik, Marlton, Paula, Roberts, Andrew W, Raca, Gordana, Stock, Wendy, Neale, Geoffrey, Drexler, Hans G, Dickins, Ross A, Ellison, David W, Shurtleff, Sheila A, Pui, Ching-Hon, Ribeiro, Raul C, Devidas, Meenakshi, Carroll, Andrew J, Heerema, Nyla A, Wood, Brent, Borowitz, Michael J, Gastier-Foster, Julie M, Raimondi, Susana C, Mardis, Elaine R, Wilson, Richard K, Downing, James R, Hunger, Stephen P, Loh, Mignon L, Mullighan, Charles G
Published in Nature genetics (01.03.2013)
Published in Nature genetics (01.03.2013)
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Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia
Roberts, Kathryn G., Morin, Ryan D., Zhang, Jinghui, Hirst, Martin, Zhao, Yongjun, Su, Xiaoping, Chen, Shann-Ching, Payne-Turner, Debbie, Churchman, Michelle L., Harvey, Richard C., Chen, Xiang, Kasap, Corynn, Yan, Chunhua, Becksfort, Jared, Finney, Richard P., Teachey, David T., Maude, Shannon L., Tse, Kane, Moore, Richard, Jones, Steven, Mungall, Karen, Birol, Inanc, Edmonson, Michael N., Hu, Ying, Buetow, Kenneth E., Chen, I-Ming, Carroll, William L., Wei, Lei, Ma, Jing, Kleppe, Maria, Levine, Ross L., Garcia-Manero, Guillermo, Larsen, Eric, Shah, Neil P., Devidas, Meenakshi, Reaman, Gregory, Smith, Malcolm, Paugh, Steven W., Evans, William E., Grupp, Stephan A., Jeha, Sima, Pui, Ching-Hon, Gerhard, Daniela S., Downing, James R., Willman, Cheryl L., Loh, Mignon, Hunger, Stephen P., Marra, Marco A., Mullighan, Charles G.
Published in Cancer cell (14.08.2012)
Published in Cancer cell (14.08.2012)
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Genomic subtyping and therapeutic targeting of acute erythroleukemia
Iacobucci, Ilaria, Wen, Ji, Meggendorfer, Manja, Choi, John K., Shi, Lei, Pounds, Stanley B., Carmichael, Catherine L., Masih, Katherine E., Morris, Sarah M., Lindsley, R. Coleman, Janke, Laura J., Alexander, Thomas B., Song, Guangchun, Qu, Chunxu, Li, Yongjin, Payne-Turner, Debbie, Tomizawa, Daisuke, Kiyokawa, Nobutaka, Valentine, Marcus, Valentine, Virginia, Basso, Giuseppe, Locatelli, Franco, Enemark, Eric J., Kham, Shirley K. Y., Yeoh, Allen E. J., Ma, Xiaotu, Zhou, Xin, Sioson, Edgar, Rusch, Michael, Ries, Rhonda E., Stieglitz, Elliot, Hunger, Stephen P., Wei, Andrew H., To, L Bik, Lewis, Ian D., D’Andrea, Richard J., Kile, Benjamin T., Brown, Anna L., Scott, Hamish S., Hahn, Christopher N., Marlton, Paula, Pei, Deqing, Cheng, Cheng, Loh, Mignon L., Ebert, Benjamin L., Meshinchi, Soheil, Haferlach, Torsten, Mullighan, Charles G.
Published in Nature genetics (01.04.2019)
Published in Nature genetics (01.04.2019)
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