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Published in Scientific reports (10.06.2019)
Published in Scientific reports (10.06.2019)
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Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions
Wang, Feng, Chau, Bryant, West, Sean M, Kimberlin, Christopher R, Cao, Fei, Schwarz, Flavio, Aguilar, Barbara, Han, Minhua, Morishige, Winse, Bee, Christine, Dollinger, Gavin, Rajpal, Arvind, Strop, Pavel
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Published in Nature communications (02.03.2021)
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Transglutaminase 2 undergoes a large conformational change upon activation
Pinkas, Daniel M, Strop, Pavel, Brunger, Axel T, Khosla, Chaitan
Published in PLoS biology (01.12.2007)
Published in PLoS biology (01.12.2007)
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Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design
Dorywalska, Magdalena, Dushin, Russell, Moine, Ludivine, Farias, Santiago E, Zhou, Dahui, Navaratnam, Thayalan, Lui, Victor, Hasa-Moreno, Adela, Casas, Meritxell Galindo, Tran, Thomas-Toan, Delaria, Kathy, Liu, Shu-Hui, Foletti, Davide, O'Donnell, Christopher J, Pons, Jaume, Shelton, David L, Rajpal, Arvind, Strop, Pavel
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The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels
Bavi, Navid, Cortes, D Marien, Cox, Charles D, Rohde, Paul R, Liu, Weihong, Deitmer, Joachim W, Bavi, Omid, Strop, Pavel, Hill, Adam P, Rees, Douglas, Corry, Ben, Perozo, Eduardo, Martinac, Boris
Published in Nature communications (22.06.2016)
Published in Nature communications (22.06.2016)
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Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model
Zorn, Julie A, Wheeler, Matthew L, Barnes, Ralston M, Kaberna, Jim, Morishige, Winse, Harris, Marek, Huang, Richard Y-C, Lohre, Jack, Chang, Yu Ching, Chau, Bryant, Powers, Kathleen, Schindler, Ian, Neradugomma, Naveen, Thomas, Winston, Liao, Xiaoyun, Zhou, Yinhan, West, Sean M, Wang, Feng, Kotapati, Srikanth, Chen, Guodong, Yamazoe, Sayumi, Kosenko, Anastasia, Dollinger, Gavin, Sproul, Tim, Rajpal, Arvind, Strop, Pavel
Published in Scientific reports (03.03.2022)
Published in Scientific reports (03.03.2022)
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Antibodies Targeting Closely Adjacent or Minimally Overlapping Epitopes Can Displace One Another
Abdiche, Yasmina Noubia, Yeung, Andy Yik, Ni, Irene, Stone, Donna, Miles, Adam, Morishige, Winse, Rossi, Andrea, Strop, Pavel
Published in PloS one (06.01.2017)
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Tim-3 mediates T cell trogocytosis to limit antitumor immunity
Pagliano, Ornella, Morrison, Robert M, Chauvin, Joe-Marc, Banerjee, Hridesh, Davar, Diwakar, Ding, Quanquan, Tanegashima, Tokiyoshi, Gao, Wentao, Chakka, Saranya R, DeBlasio, Richelle, Lowin, Ava, Kara, Kevin, Ka, Mignane, Zidi, Bochra, Amin, Rada, Raphael, Itay, Zhang, Shuowen, Watkins, Simon C, Sander, Cindy, Kirkwood, John M, Bosenberg, Marcus, Anderson, Ana C, Kuchroo, Vijay K, Kane, Lawrence P, Korman, Alan J, Rajpal, Arvind, West, Sean M, Han, Minhua, Bee, Christine, Deng, Xiaodi, Schebye, Xiao Min, Strop, Pavel, Zarour, Hassane M
Published in The Journal of clinical investigation (01.05.2022)
Published in The Journal of clinical investigation (01.05.2022)
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Universal Affinity Capture Liquid Chromatography-Mass Spectrometry Assay for Evaluation of Biotransformation of Site-Specific Antibody Drug Conjugates in Preclinical Studies
Kotapati, Srikanth, Passmore, David, Yamazoe, Sayumi, Sanku, Rajesh Kishore Kumar, Cong, Qiang, Poudel, Yam B, Chowdari, Naidu S, Gangwar, Sanjeev, Rao, Chetana, Rangan, Vangipuram S, Cardarelli, Pina M, Deshpande, Shrikant, Strop, Pavel, Dollinger, Gavin, Rajpal, Arvind
Published in Analytical chemistry (Washington) (21.01.2020)
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Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT
Diong, SJ J., Jashnani, Aarti, Drake, Andrew W., Bee, Christine, Findeisen, Felix, Dollinger, Gavin, Wang, Feng, Rajpal, Arvind, Strop, Pavel, Lee, Peter S.
Published in mAbs (31.12.2023)
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Generating Bispecific Human IgG1 and IgG2 Antibodies from Any Antibody Pair
Strop, Pavel, Ho, Wei-Hsien, Boustany, Leila M., Abdiche, Yasmina N., Lindquist, Kevin C., Farias, Santiago E., Rickert, Mathias, Appah, Charles Takeshi, Pascua, Edward, Radcliffe, Teresa, Sutton, Janette, Chaparro-Riggers, Javier, Chen, Wei, Casas, Meritxell Galindo, Chin, Sherman Michael, Wong, Oi Kwan, Liu, Shu-Hui, Vergara, German, Shelton, Dave, Rajpal, Arvind, Pons, Jaume
Published in Journal of molecular biology (13.07.2012)
Published in Journal of molecular biology (13.07.2012)
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Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates
Liang, Hong, Chaparro-Riggers, Javier, Strop, Pavel, Geng, Tao, Sutton, Janette E, Tsai, Daniel, Bai, Lanfang, Abdiche, Yasmina, Dilley, Jeanette, Yu, Jessica, Wu, Si, Chin, S Michael, Lee, Nicole A, Rossi, Andrea, Lin, John C, Rajpal, Arvind, Pons, Jaume, Shelton, David L
Published in The Journal of pharmacology and experimental therapeutics (01.02.2012)
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Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire
Yeung, Yik Andy, Foletti, Davide, Deng, Xiaodi, Abdiche, Yasmina, Strop, Pavel, Glanville, Jacob, Pitts, Steven, Lindquist, Kevin, Sundar, Purnima D, Sirota, Marina, Hasa-Moreno, Adela, Pham, Amber, Melton Witt, Jody, Ni, Irene, Pons, Jaume, Shelton, David, Rajpal, Arvind, Chaparro-Riggers, Javier
Published in Nature communications (18.11.2016)
Published in Nature communications (18.11.2016)
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Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies
Shcherbatko, Anatoly, Foletti, Davide, Poulsen, Kris, Strop, Pavel, Zhu, Guoyun, Hasa-Moreno, Adela, Melton Witt, Jody, Loo, Carole, Krimm, Stellanie, Pios, Ariel, Yu, Jessica, Brown, Colleen, Lee, John K., Stroud, Robert, Rajpal, Arvind, Shelton, David
Published in The Journal of biological chemistry (03.06.2016)
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Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy
Dorywalska, Magdalena, Strop, Pavel, Melton-Witt, Jody A, Hasa-Moreno, Adela, Farias, Santiago E, Galindo Casas, Meritxell, Delaria, Kathy, Lui, Victor, Poulsen, Kris, Sutton, Janette, Bolton, Gary, Zhou, Dahui, Moine, Ludivine, Dushin, Russell, Tran, Thomas-Toan, Liu, Shu-Hui, Rickert, Mathias, Foletti, Davide, Shelton, David L, Pons, Jaume, Rajpal, Arvind
Published in PloS one (10.07.2015)
Published in PloS one (10.07.2015)
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A method for integrative structure determination of protein-protein complexes
SCHNEIDMAN-DUHOVNY, Dina, ROSSI, Andrea, SOBHANIFAR, Solmaz, DÖTSCH, Volker, RAJPAL, Arvind, PONS, Jaume, AGARD, David A, YIFAN CHENG, SALI, Andrej, AVILA-SAKAR, Agustin, SEUNG JOONG KIM, VELAZQUEZ-MURIEL, Javier, STROP, Pavel, HONG LIANG, KRUKENBERG, Kristin A, MAOFU LIAO, HO MIN KIM
Published in Bioinformatics (01.12.2012)
Published in Bioinformatics (01.12.2012)
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Improved therapeutic index of an acidic pH-selective antibody
Lee, Peter S, MacDonald, Katherine G, Massi, Evan, Chew, Pamela V, Bee, Christine, Perkins, Padma, Chau, Bryant, Thudium, Kent, Lohre, Jack, Nandi, Pradyot, Deyanova, Ekaterina G, Barman, Ishita, Gudmundsson, Olafur, Dollinger, Gavin, Sproul, Tim, Engelhardt, John J, Strop, Pavel, Rajpal, Arvind
Published in mAbs (2022)
Published in mAbs (2022)
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Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates
Costa, Maria José, Kudaravalli, Jyothirmayee, Ma, Jing-Tyan, Ho, Wei-Hsien, Delaria, Kathy, Holz, Charles, Stauffer, Angela, Chunyk, Allison Given, Zong, Qing, Blasi, Eileen, Buetow, Bernard, Tran, Thomas-Toan, Lindquist, Kevin, Dorywalska, Magdalena, Rajpal, Arvind, Shelton, David L, Strop, Pavel, Liu, Shu-Hui
Published in Scientific reports (21.02.2019)
Published in Scientific reports (21.02.2019)
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