Utilization of treatment effect on a surrogate endpoint for planning a study to evaluate treatment effect on a final endpoint
Quan, Hui, Xu, Zhixing, Luo, Junxiang, Paux, Gautier, Cho, Meehyung, Chen, Xun
Published in Pharmaceutical statistics : the journal of the pharmaceutical industry (01.07.2023)
Published in Pharmaceutical statistics : the journal of the pharmaceutical industry (01.07.2023)
Get full text
Journal Article
AMEERA-1 phase 1/2 study of amcenestrant, SAR439859, in postmenopausal women with ER-positive/HER2-negative advanced breast cancer
Bardia, Aditya, Chandarlapaty, Sarat, Linden, Hannah M., Ulaner, Gary A., Gosselin, Alice, Cartot-Cotton, Sylvaine, Cohen, Patrick, Doroumian, Séverine, Paux, Gautier, Celanovic, Marina, Pelekanou, Vasiliki, Ming, Jeffrey E., Ternès, Nils, Bouaboula, Monsif, Lee, Joon Sang, Bauchet, Anne-Laure, Campone, Mario
Published in Nature communications (15.07.2022)
Published in Nature communications (15.07.2022)
Get full text
Journal Article
AMEERA-4: a randomized, preoperative window-of-opportunity study of amcenestrant versus letrozole in early breast cancer
Campone, Mario, Bidard, François-Clément, Neven, Patrick, Wang, Lei, Ling, Bin, Dong, Yvonne, Paux, Gautier, Herold, Christina, De Giorgi, Ugo
Published in Breast cancer research : BCR (10.11.2023)
Published in Breast cancer research : BCR (10.11.2023)
Get full text
Journal Article
Adjuvant endocrine therapy uptake, toxicity, quality of life, and prediction of early discontinuation
Balazard, Félix, Bertaut, Aurélie, Bordet, Élise, Mulard, Stéphane, Blanc, Julie, Briot, Nathalie, Paux, Gautier, Dhaini Merimeche, Asma, Rigal, Olivier, Coutant, Charles, Fournier, Marion, Jouannaud, Christelle, Soulie, Patrick, Lerebours, Florence, Cottu, Paul-Henri, Tredan, Olivier, Vanlemmens, Laurence, Levy, Christelle, Mouret-Reynier, Marie-Ange, Campone, Mario, Brady, Keri J S, Sasane, Medha, Rice, Megan, Coulouvrat, Catherine, Martin, Anne-Laure, Jacquet, Alexandra, Vaz-Luis, Ines, Herold, Christina, Pistilli, Barbara
Published in JNCI : Journal of the National Cancer Institute (07.09.2023)
Published in JNCI : Journal of the National Cancer Institute (07.09.2023)
Get full text
Journal Article
Applications of Bayesian analysis to proof‐of‐concept trial planning and decision making
Quan, Hui, Chen, Xun, Lan, Yu, Luo, Xiaodong, Kubiak, Rene, Bonnet, Nicolas, Paux, Gautier
Published in Pharmaceutical statistics : the journal of the pharmaceutical industry (01.07.2020)
Published in Pharmaceutical statistics : the journal of the pharmaceutical industry (01.07.2020)
Get full text
Journal Article
Use of Seamless Study Designs in Oncology Clinical Development– A Survey Conducted by IDSWG Oncology Sub-team
Dong, Yingwen, Paux, Gautier, Broglio, Kristine, Cooner, Freda, Gao, Guozhi, He, Wei, Gao, Lei, Xue, Xiaoqiang, He, Philip
Published in Therapeutic innovation & regulatory science (01.09.2024)
Published in Therapeutic innovation & regulatory science (01.09.2024)
Get full text
Journal Article
Development of gatekeeping strategies in confirmatory clinical trials
Dmitrienko, Alex, Millen, Brian A., Brechenmacher, Thomas, Paux, Gautier
Published in Biometrical journal (01.11.2011)
Published in Biometrical journal (01.11.2011)
Get full text
Journal Article
POWER CALCULATIONS IN CLINICAL TRIALS WITH COMPLEX CLINICAL OBJECTIVES
Dmitrienko, Alex, Paux, Gautier, Brechenmacher, Thomas
Published in Journal of the Japanese Society of Computational Statistics (01.01.2015)
Published in Journal of the Japanese Society of Computational Statistics (01.01.2015)
Get full text
Journal Article
Reply to Y. Yoshitomi et al
Tolaney, Sara M, De Kermadec, Elisabeth, Cohen, Patrick, Paux, Gautier, Wang, Lei, Im, Seock-Ah
Published in Journal of clinical oncology (10.01.2024)
Published in Journal of clinical oncology (10.01.2024)
Get full text
Journal Article
AMEERA-3: Randomized Phase II Study of Amcenestrant (Oral Selective Estrogen Receptor Degrader) Versus Standard Endocrine Monotherapy in Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer
Tolaney, Sara M, Chan, Arlene, Petrakova, Katarina, Delaloge, Suzette, Campone, Mario, Iwata, Hiroji, Peddi, Parvin F, Kaufman, Peter A, De Kermadec, Elisabeth, Liu, Qianying, Cohen, Patrick, Paux, Gautier, Wang, Lei, Ternès, Nils, Boitier, Eric, Im, Seock-Ah
Published in Journal of clinical oncology (20.08.2023)
Published in Journal of clinical oncology (20.08.2023)
Get full text
Journal Article
Implementation of adaptive methods in early‐phase clinical trials
Petroni, Gina R., Wages, Nolan A., Paux, Gautier, Dubois, Frédéric
Published in Statistics in medicine (30.01.2017)
Published in Statistics in medicine (30.01.2017)
Get full text
Journal Article
Randomized Phase III Study of Amcenestrant Plus Palbociclib Versus Letrozole Plus Palbociclib in Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Primary Results From AMEERA-5
Cortés, Javier, Hurvitz, Sara A, O'Shaughnessy, Joyce, Delaloge, Suzette, Iwata, Hiroji, Rugo, Hope S, Neven, Patrick, Kanagavel, Dheepak, Cohen, Patrick, Paux, Gautier, Cartot-Cotton, Sylvaine, Stefanova-Urena, Maya, Deyme, Laure, Aouni, Jihane, Sebastien, Bernard, Bardia, Aditya
Published in Journal of clinical oncology (01.08.2024)
Published in Journal of clinical oncology (01.08.2024)
Get full text
Journal Article
Phase III (IMROZ) study design: Isatuximab plus bortezomib (V), lenalidomide (R), and dexamethasone (d) vs VRd in transplant-ineligible patients (pts) with newly diagnosed multiple myeloma (NDMM)
Orlowski, Robert Z., Goldschmidt, Hartmut, Cavo, Michele, Martin, Thomas G., Paux, Gautier, Oprea, Corina, Facon, Thierry
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
Get full text
Journal Article
Abstract P1-17-11: Updated data from AMEERA-1: Phase 1/2 study of amcenestrant (SAR439859), an oral selective estrogen receptor (ER) degrader (SERD), combined with palbociclib in postmenopausal women with ER+/HER2- advanced breast cancer
Chandarlapaty, Sarat, Linden, Hannah M, Neven, Patrick, Petrakova, Katarina, Bardia, Aditya, Kabos, Peter, Braga, Sofia, Boni, Valentina, Gosselin, Alice, Celanovic, Marina, Cohen, Patrick, Paux, Gautier, Pelekanou, Vasiliki, Ternès, Nils, Lee, Joon Sang, Campone, Mario
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Get full text
Journal Article
AMEERA-1: Phase 1/2 study of amcenestrant (SAR439859), an oral selective estrogen receptor (ER) degrader (SERD), with palbociclib (palbo) in postmenopausal women with ER+/ human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer (mBC)
Chandarlapaty, Sarat, Linden, Hannah M., Neven, Patrick, Petrakova, Katarina, Bardia, Aditya, Kabos, Peter, Braga, Sofia A. D. S., Boni, Valentina, Gosselin, Alice, Cartot-Cotton, Sylvaine, Doroumian, Séverine, Celanovic, Marina, Cohen, Patrick, Paux, Gautier, Campone, Mario
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article
Adjuvant study of amcenestrant (SAR439859) versus tamoxifen for patients with hormone receptor-positive (HR+) early breast cancer (EBC), who have discontinued adjuvant aromatase inhibitor therapy due to treatment-related toxicity (AMEERA-6)
Meyskens, Thomas, Metzger, Otto, Poncet, Coralie, Goulioti, Theodora, Xenophontos, Eleni, Carey, Lisa A., Wang, Lei, Rossi, Giovanna, Gilham, Leslie, De Swert, Heidi, Casas-Martin, Jose, Attieh, Elham, Arahmani, Amal, De Meulemeester, Laura, Partridge, Ann H., Herold, Christina Isabella, Paux, Gautier, Dueck, Amylou C., Brain, Etienne, Cameron, David A.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
Get full text
Journal Article
Abstract P1-13-08: Patterns of adjuvant endocrine therapy, discontinuations, toxicities and quality of life: Development of a model for early discontinuation using the CANTO cohort
Balazard, Felix, Bertaut, Aurélie, Bordet, Élise, Mulard, Stéphane, Blanc, Julie, Briot, Nathalie, Paux, Gautier, Merimeche, Asma Dhaini, Rigal, Olivier, Coutant, Charles, Fournier, Marion, Jouannaud, Christelle, Soulie, Patrick, Lerebours, Florence, Cottu, Paul-Henri, Tredan, Olivier, Vanlemmens, Laurence, Levy, Christelle, Mouret-Reynier, Marie-Ange, Campone, Mario, Brady, Keri J. S., Sasane, Medha, Rice, Megan, Coulouvrat, Catherine, Martin, Anne-Laure, Jacquet, Alexandra, Vaz-Luis, Ines, Herold, Christina, Pistilli, Barbara
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Get full text
Journal Article