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Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors
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Molecular Structures of Human Factor Xa Complexed with Ketopiperazine Inhibitors: Preference for a Neutral Group in the S1 Pocket
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Discovery of Pyrazolo[1,5‑a]pyrimidine TTK Inhibitors: CFI-402257 is a Potent, Selective, Bioavailable Anticancer Agent
Liu, Yong, Laufer, Radoslaw, Patel, Narendra Kumar, Ng, Grace, Sampson, Peter B, Li, Sze-Wan, Lang, Yunhui, Feher, Miklos, Brokx, Richard, Beletskaya, Irina, Hodgson, Richard, Plotnikova, Olga, Awrey, Donald E, Qiu, Wei, Chirgadze, Nickolay Y, Mason, Jacqueline M, Wei, Xin, Lin, Dan Chi-Chia, Che, Yi, Kiarash, Reza, Fletcher, Graham C, Mak, Tak W, Bray, Mark R, Pauls, Henry W
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Design and optimization of (3-aryl-1H-indazol-6-yl)spiro[cyclopropane-1,3′-indolin]-2′-ones as potent PLK4 inhibitors with oral antitumor efficacy
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Published in Bioorganic & medicinal chemistry letters (01.10.2016)
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Discovery of 4-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)benzamides as novel, highly potent and selective, orally bioavailable inhibitors of Tyrosine Threonine Kinase, TTK
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Published in Bioorganic & medicinal chemistry letters (01.08.2016)
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In vitro activity (MICs and rate of kill) of AFN-1252, a novel FabI inhibitor, in the presence of serum and in combination with other antibiotics
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Design and Structure−Activity Relationships of Potent and Selective Inhibitors of Blood Coagulation Factor Xa
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Published in Journal of medicinal chemistry (09.09.1999)
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Lagrangian singularities of steady two-dimensional flow
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Published in Geophysical and astrophysical fluid dynamics (01.02.2005)
Published in Geophysical and astrophysical fluid dynamics (01.02.2005)
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In Vitro Characterization of a Novel Factor Xa Inhibitor, RPR 130737
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Published in Thrombosis research (01.07.2000)
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The discovery of Polo-like kinase 4 inhibitors: design and optimization of spiro[cyclopropane-1,3'[3H]indol]-2'(1'H).ones as orally bioavailable antitumor agents
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Published in Journal of medicinal chemistry (08.01.2015)
Published in Journal of medicinal chemistry (08.01.2015)
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