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tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers
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A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer
Lucki, Natasha C., Villa, Genaro R., Vergani, Naja, Bollong, Michael J., Beyer, Brittney A., Lee, Jae Wook, Anglin, Justin L., Spangenberg, Stephan H., Chin, Emily N., Sharma, Amandeep, Johnson, Kevin, Sander, Philipp N., Gordon, Perry, Skirboll, Stephen L., Wurdak, Heiko, Schultz, Peter G., Mischel, Paul S., Lairson, Luke L.
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Musashi1 Cooperates in Abnormal Cell Lineage Protein 28 (Lin28)-mediated Let-7 Family MicroRNA Biogenesis in Early Neural Differentiation
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Neurosphere Formation Is an Independent Predictor of Clinical Outcome in Malignant Glioma
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EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy
Guo, Deliang, Prins, Robert M, Dang, Julie, Kuga, Daisuke, Iwanami, Akio, Soto, Horacio, Lin, Kelly Y, Huang, Tiffany T, Akhavan, David, Hock, M Benjamin, Zhu, Shaojun, Kofman, Ava A, Bensinger, Steve J, Yong, William H, Vinters, Harry V, Horvath, Steve, Watson, Andrew D, Kuhn, John G, Robins, H Ian, Mehta, Minesh P, Wen, Patrick Y, DeAngelis, Lisa M, Prados, Michael D, Mellinghoff, Ingo K, Cloughesy, Timothy F, Mischel, Paul S
Published in Science signaling (15.12.2009)
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On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment
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Published in Experimental cell research (15.07.2013)
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PTEN-Mediated Resistance to Epidermal Growth Factor Receptor Kinase Inhibitors
MELLINGHOFF, Ingo K, CLOUGHESY, Tim F, MISCHEL, Paul S
Published in Clinical cancer research (15.01.2007)
Published in Clinical cancer research (15.01.2007)
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DNA hypomethylator phenotype reprograms glutamatergic network in receptor tyrosine kinase gene-mutated glioblastoma
Harachi, Mio, Masui, Kenta, Shimizu, Erika, Murakami, Kumiko, Onizuka, Hiromi, Muragaki, Yoshihiro, Kawamata, Takakazu, Nakayama, Hisako, Miyata, Mariko, Komori, Takashi, Cavenee, Webster K, Mischel, Paul S, Kurata, Atsushi, Shibata, Noriyuki
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Protein Acetylation at the Interface of Genetics, Epigenetics and Environment in Cancer
Harachi, Mio, Masui, Kenta, Cavenee, Webster K, Mischel, Paul S, Shibata, Noriyuki
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Wykosky, Jill, Hu, Jingjing, Gomez, German G, Taylor, Tiffany, Villa, Genaro R, Pizzo, Donald, VandenBerg, Scott R, Thorne, Amy Haseley, Chen, Clark C, Mischel, Paul S, Gonias, Steven L, Cavenee, Webster K, Furnari, Frank B
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Dendritic Cell Vaccination in Glioblastoma Patients Induces Systemic and Intracranial T-cell Responses Modulated by the Local Central Nervous System Tumor Microenvironment
Liau, Linda M, Prins, Robert M, Kiertscher, Sylvia M, Odesa, Sylvia K, Kremen, Thomas J, Giovannone, Adrian J, Lin, Jia-Wei, Chute, Dennis J, Mischel, Paul S, Cloughesy, Timothy F, Roth, Michael D
Published in Clinical cancer research (01.08.2005)
Published in Clinical cancer research (01.08.2005)
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Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240
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Published in Proceedings of the National Academy of Sciences - PNAS (28.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (28.08.2012)
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Hypoxia induces a phase transition within a kinase signaling network in cancer cells
Wei, Wei, Shi, Qihui, Remacle, Francoise, Qin, Lidong, Shackelford, David B, Shin, Young Shik, Mischel, Paul S, Levine, R D, Heath, James R
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
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mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma
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Published in Science translational medicine (20.06.2012)
Published in Science translational medicine (20.06.2012)
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