High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor
Groot-Kormelink, Paul J, Ferrand, Sandrine, Kelley, Nicholas, Bill, Anke, Freuler, Felix, Imbert, Pierre-Eloi, Marelli, Anthony, Gerwin, Nicole, Sivilotti, Lucia G, Miraglia, Loren, Orth, Anthony P, Oakeley, Edward J, Schopfer, Ulrich, Siehler, Sandra
Published in PloS one (20.09.2016)
Published in PloS one (20.09.2016)
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Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease
Miller, Andrew T, Dahlberg, Carol, Sandberg, Mark L, Wen, Ben G, Beisner, Daniel R, Hoerter, John A H, Parker, Albert, Schmedt, Christian, Stinson, Monique, Avis, Jacqueline, Cienfuegos, Cynthia, McPate, Mark, Tranter, Pamela, Gosling, Martin, Groot-Kormelink, Paul J, Dawson, Janet, Pan, Shifeng, Tian, Shin-Shay, Seidel, H Martin, Cooke, Michael P
Published in PloS one (29.06.2015)
Published in PloS one (29.06.2015)
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Human α3β4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells
Krashia, Paraskevi, Moroni, Mirko, Broadbent, Steven, Hofmann, Giovanna, Kracun, Sebastian, Beato, Marco, Groot-Kormelink, Paul J, Sivilotti, Lucia G
Published in PloS one (26.10.2010)
Published in PloS one (26.10.2010)
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High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function
Bill, Anke, Rosethorne, Elizabeth M, Kent, Toby C, Fawcett, Lindsay, Burchell, Lynn, van Diepen, Michiel T, Marelli, Anthony, Batalov, Sergey, Miraglia, Loren, Orth, Anthony P, Renaud, Nicole A, Charlton, Steven J, Gosling, Martin, Gaither, L Alex, Groot-Kormelink, Paul J
Published in PloS one (02.06.2014)
Published in PloS one (02.06.2014)
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Constraining the Expression of Nicotinic Acetylcholine Receptors by Using Pentameric Constructs
Groot-Kormelink, Paul J, Broadbent, Steven, Beato, Marco, Sivilotti, Lucia G
Published in Molecular pharmacology (01.02.2006)
Published in Molecular pharmacology (01.02.2006)
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Cholinergic drugs potentiate human nicotinic α4β2 acetylcholine receptors by a competitive mechanism
Smulders, Chantal J.G.M., Zwart, Ruud, Bermudez, Isabel, van Kleef, Regina G.D.M., Groot-Kormelink, Paul J., Vijverberg, Henk P.M.
Published in European journal of pharmacology (01.02.2005)
Published in European journal of pharmacology (01.02.2005)
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Human alpha 3 beta 4 Neuronal Nicotinic Receptors Show Different Stoichiometry if They Are Expressed in Xenopus Oocytes or Mammalian HEK293 Cells
Krashia, Paraskevi, Moroni, Mirko, Broadbent, Steven, Hofmann, Giovanna, Kracun, Sebastian, Beato, Marco, Groot-Kormelink, Paul J, Sivilotti, Lucia G
Published in PloS one (26.10.2010)
Published in PloS one (26.10.2010)
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Single-Channel Behavior of Heteromeric α1β Glycine Receptors: An Attempt to Detect a Conformational Change before the Channel Opens
Burzomato, Valeria, Beato, Marco, Groot-Kormelink, Paul J., Colquhoun, David, Sivilotti, Lucia G.
Published in The Journal of neuroscience (01.12.2004)
Published in The Journal of neuroscience (01.12.2004)
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Variomics Screen Identifies the Re-entrant Loop of the Calcium-activated Chloride Channel ANO1 That Facilitates Channel Activation
Bill, Anke, Popa, M. Oana, van Diepen, Michiel T., Gutierrez, Abraham, Lilley, Sarah, Velkova, Maria, Acheson, Kathryn, Choudhury, Hedaythul, Renaud, Nicole A., Auld, Douglas S., Gosling, Martin, Groot-Kormelink, Paul J., Gaither, L. Alex
Published in The Journal of biological chemistry (09.01.2015)
Published in The Journal of biological chemistry (09.01.2015)
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Incorporation of the beta 3 Subunit Has a Dominant-Negative Effect on the Function of Recombinant Central-Type Neuronal Nicotinic Receptors
Broadbent, Steven, Groot-Kormelink, Paul J, Krashia, Paraskevi A, Harkness, Patricia C, Millar, Neil S, Beato, Marco, Sivilotti, Lucia G
Published in Molecular pharmacology (01.10.2006)
Published in Molecular pharmacology (01.10.2006)
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Journal Article
Incorporation of the β3 Subunit Has a Dominant-Negative Effect on the Function of Recombinant Central-Type Neuronal Nicotinic Receptors
Broadbent, Steven, Groot-Kormelink, Paul J., Krashia, Paraskevi A., Harkness, Patricia C., Millar, Neil S., Beato, Marco, Sivilotti, Lucia G.
Published in Molecular pharmacology (01.10.2006)
Published in Molecular pharmacology (01.10.2006)
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The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7
McPate, Mark, Bhalay, Gurdip, Beckett, Martin, Fairbrother, Sian, Gosling, Martin, Groot-Kormelink, Paul J, Lane, Rebecca, Kent, Toby, Van Diepen, Michiel T, Tranter, Pamela, Verkuyl, J Martin
Published in Assay and drug development technologies (01.06.2014)
Published in Assay and drug development technologies (01.06.2014)
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Achieving optimal expression for single channel recording: a plasmid ratio approach to the expression of α1 glycine receptors in HEK293 cells
Groot-Kormelink, Paul J, Beato, Marco, Finotti, Chiara, Harvey, Robert J, Sivilotti, Lucia G
Published in Journal of neuroscience methods (2002)
Published in Journal of neuroscience methods (2002)
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