Adverse Events Following Cancer Immunotherapy: Obstacles and Opportunities
Pauken, Kristen E., Dougan, Michael, Rose, Noel R., Lichtman, Andrew H., Sharpe, Arlene H.
Published in Trends in immunology (01.06.2019)
Published in Trends in immunology (01.06.2019)
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Emerging concepts in PD-1 checkpoint biology
Pauken, Kristen E., Torchia, James A., Chaudhri, Apoorvi, Sharpe, Arlene H., Freeman, Gordon J.
Published in Seminars in immunology (01.02.2021)
Published in Seminars in immunology (01.02.2021)
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The role of the PD-1 pathway in autoimmunity and peripheral tolerance
Fife, Brian T., Pauken, Kristen E.
Published in Annals of the New York Academy of Sciences (01.01.2011)
Published in Annals of the New York Academy of Sciences (01.01.2011)
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CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
Gupta, Prakash K, Godec, Jernej, Wolski, David, Adland, Emily, Yates, Kathleen, Pauken, Kristen E, Cosgrove, Cormac, Ledderose, Carola, Junger, Wolfgang G, Robson, Simon C, Wherry, E John, Alter, Galit, Goulder, Philip J R, Klenerman, Paul, Sharpe, Arlene H, Lauer, Georg M, Haining, W Nicholas
Published in PLoS pathogens (01.10.2015)
Published in PLoS pathogens (01.10.2015)
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Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade
Benci, Joseph L., Xu, Bihui, Qiu, Yu, Wu, Tony J., Dada, Hannah, Twyman-Saint Victor, Christina, Cucolo, Lisa, Lee, David S.M., Pauken, Kristen E., Huang, Alexander C., Gangadhar, Tara C., Amaravadi, Ravi K., Schuchter, Lynn M., Feldman, Michael D., Ishwaran, Hemant, Vonderheide, Robert H., Maity, Amit, Wherry, E. John, Minn, Andy J.
Published in Cell (01.12.2016)
Published in Cell (01.12.2016)
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Resident memory CD8 T cells trigger protective innate and adaptive immune responses
Schenkel, Jason M., Fraser, Kathryn A., Beura, Lalit K., Pauken, Kristen E., Vezys, Vaiva, Masopust, David
Published in Science (American Association for the Advancement of Science) (03.10.2014)
Published in Science (American Association for the Advancement of Science) (03.10.2014)
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Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8+ T Cell Exhaustion
Bengsch, Bertram, Johnson, Andy L., Kurachi, Makoto, Odorizzi, Pamela M., Pauken, Kristen E., Attanasio, John, Stelekati, Erietta, McLane, Laura M., Paley, Michael A., Delgoffe, Greg M., Wherry, E. John
Published in Immunity (Cambridge, Mass.) (16.08.2016)
Published in Immunity (Cambridge, Mass.) (16.08.2016)
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Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
Twyman-Saint Victor, Christina, Rech, Andrew J., Maity, Amit, Rengan, Ramesh, Pauken, Kristen E., Stelekati, Erietta, Benci, Joseph L., Xu, Bihui, Dada, Hannah, Odorizzi, Pamela M., Herati, Ramin S., Mansfield, Kathleen D., Patsch, Dana, Amaravadi, Ravi K., Schuchter, Lynn M., Ishwaran, Hemant, Mick, Rosemarie, Pryma, Daniel A., Xu, Xiaowei, Feldman, Michael D., Gangadhar, Tara C., Hahn, Stephen M., Wherry, E. John, Vonderheide, Robert H., Minn, Andy J.
Published in Nature (London) (16.04.2015)
Published in Nature (London) (16.04.2015)
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Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
Pauken, Kristen E., Sammons, Morgan A., Odorizzi, Pamela M., Manne, Sasikanth, Godec, Jernej, Khan, Omar, Drake, Adam M., Chen, Zeyu, Sen, Debattama R., Kurachi, Makoto, Barnitz, R. Anthony, Bartman, Caroline, Bengsch, Bertram, Huang, Alexander C., Schenkel, Jason M., Vahedi, Golnaz, Haining, W. Nicholas, Berger, Shelley L., Wherry, E. John
Published in Science (American Association for the Advancement of Science) (02.12.2016)
Published in Science (American Association for the Advancement of Science) (02.12.2016)
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T-cell invigoration to tumour burden ratio associated with anti-PD-1 response
Huang, Alexander C., Postow, Michael A., Orlowski, Robert J., Mick, Rosemarie, Bengsch, Bertram, Manne, Sasikanth, Xu, Wei, Harmon, Shannon, Giles, Josephine R., Wenz, Brandon, Adamow, Matthew, Kuk, Deborah, Panageas, Katherine S., Carrera, Cristina, Wong, Phillip, Quagliarello, Felix, Wubbenhorst, Bradley, D’Andrea, Kurt, Pauken, Kristen E., Herati, Ramin S., Staupe, Ryan P., Schenkel, Jason M., McGettigan, Suzanne, Kothari, Shawn, George, Sangeeth M., Vonderheide, Robert H., Amaravadi, Ravi K., Karakousis, Giorgos C., Schuchter, Lynn M., Xu, Xiaowei, Nathanson, Katherine L., Wolchok, Jedd D., Gangadhar, Tara C., Wherry, E. John
Published in Nature (London) (04.05.2017)
Published in Nature (London) (04.05.2017)
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Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
Fife, Brian T, Pauken, Kristen E, Eagar, Todd N, Obu, Takashi, Wu, Jenny, Tang, Qizhi, Azuma, Miyuki, Krummel, Matthew F, Bluestone, Jeffrey A
Published in Nature immunology (01.11.2009)
Published in Nature immunology (01.11.2009)
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Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes
Schenkel, Jason M., Herbst, Rebecca H., Canner, David, Li, Amy, Hillman, Michelle, Shanahan, Sean-Luc, Gibbons, Grace, Smith, Olivia C., Kim, Jonathan Y., Westcott, Peter, Hwang, William L., Freed-Pastor, William A., Eng, George, Cuoco, Michael S., Rogers, Patricia, Park, Jin K., Burger, Megan L., Rozenblatt-Rosen, Orit, Cong, Le, Pauken, Kristen E., Regev, Aviv, Jacks, Tyler
Published in Immunity (Cambridge, Mass.) (12.10.2021)
Published in Immunity (Cambridge, Mass.) (12.10.2021)
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