Role of the Exchange Protein Directly Activated by Cyclic Adenosine 5′-Monophosphate (Epac) Pathway in Regulating Proglucagon Gene Expression in Intestinal Endocrine L Cells
Lotfi, Shamim, Li, Zhihong, Sun, Jane, Zuo, Yang, Lam, Patrick P. L, Kang, Youhou, Rahimi, Mehdi, Islam, Diana, Wang, Peixiang, Gaisano, Herbert Y, Jin, Tianru
Published in Endocrinology (Philadelphia) (01.08.2006)
Published in Endocrinology (Philadelphia) (01.08.2006)
Get full text
Journal Article
Elevation in Intracellular Long-Chain Acyl-Coenzyme A Esters Lead to Reduced β-Cell Excitability via Activation of Adenosine 5′-Triphosphate-Sensitive Potassium Channels
Webster, Nicola J, Searle, Gavin J, Lam, Patrick P. L, Huang, Ya-Chi, Riedel, Michael J, Harb, George, Gaisano, Herbert Y, Holt, Andrew, Light, Peter E
Published in Endocrinology (Philadelphia) (01.07.2008)
Published in Endocrinology (Philadelphia) (01.07.2008)
Get full text
Journal Article
Transgenic Mouse Overexpressing Syntaxin-1A as a Diabetes Model
LAM, Patrick P. L, LEUNG, Yuk-Man, SHEU, Laura, ELLIS, James, TSUSHIMA, Robert G, OSBORNE, Lucy R, GAISANO, Herbert Y
Published in Diabetes (New York, N.Y.) (01.09.2005)
Published in Diabetes (New York, N.Y.) (01.09.2005)
Get full text
Journal Article
Dual Role of VAMP8 in Regulating Insulin Exocytosis and Islet β Cell Growth
Zhu, Dan, Zhang, Yi, Lam, Patrick P.L., Dolai, Subhankar, Liu, Yunfeng, Cai, Erica P., Choi, Diana, Schroer, Stephanie A., Kang, Youhou, Allister, Emma M., Qin, Tairan, Wheeler, Michael B., Wang, Cheng-Chun, Hong, Wan-Jin, Woo, Minna, Gaisano, Herbert Y.
Published in Cell metabolism (08.08.2012)
Published in Cell metabolism (08.08.2012)
Get full text
Journal Article
Alcohol/Cholecystokinin-evoked Pancreatic Acinar Basolateral Exocytosis Is Mediated by Protein Kinase Cα Phosphorylation of Munc18c
Cosen-Binker, Laura I., Lam, Patrick P.L., Binker, Marcelo G., Reeve, Joseph, Pandol, Stephen, Gaisano, Herbert Y.
Published in The Journal of biological chemistry (27.04.2007)
Published in The Journal of biological chemistry (27.04.2007)
Get full text
Journal Article
Deletion of Fas in the pancreatic beta-cells leads to enhanced insulin secretion
Choi, Diana, Radziszewska, Anna, Schroer, Stephanie A, Liadis, Nicole, Liu, Yunfeng, Zhang, Yi, Lam, Patrick P L, Sheu, Laura, Hao, Zhenyue, Gaisano, Herbert Y, Woo, Minna
Published in American journal of physiology: endocrinology and metabolism (01.12.2009)
Published in American journal of physiology: endocrinology and metabolism (01.12.2009)
Get full text
Journal Article
A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini
Lam, Patrick P L, Hyvärinen, Kati, Kauppi, Maria, Cosen-Binker, Laura, Laitinen, Saara, Keränen, Sirkka, Gaisano, Herbert Y, Olkkonen, Vesa M
Published in Molecular biology of the cell (01.07.2007)
Published in Molecular biology of the cell (01.07.2007)
Get full text
Journal Article
Munc18b Is a Major Mediator of Insulin Exocytosis in Rat Pancreatic β-Cells
LAM, Patrick P. L, OHNO, Mitsuyo, LI XIE, WAN, Wilson C. Y, BIN, Na-Rhum, SUGITA, Shuzo, OLKKONEN, Vesa M, TAKAHASHI, Noriko, KASAI, Haruo, GAISANO, Herbert Y, DOLAI, Subhankar, YU HE, TAIRAN QIN, TAO LIANG, DAN ZHU, YOUHOU KANG, YUNFENG LIU, KAUPPI, Maria
Published in Diabetes (New York, N.Y.) (01.07.2013)
Published in Diabetes (New York, N.Y.) (01.07.2013)
Get full text
Journal Article
Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis
Xia, Fuzhen, Gao, Xiaodong, Kwan, Edwin, Lam, Patrick P L, Chan, Lillian, Sy, Keiyan, Sheu, Laura, Wheeler, Michael B, Gaisano, Herbert Y, Tsushima, Robert G
Published in The Journal of biological chemistry (04.06.2004)
Published in The Journal of biological chemistry (04.06.2004)
Get full text
Journal Article
Munc18b is a major mediator of insulin exocytosis in rat pancreatic [beta]-cells
Lain, Patrick P.L, Ohno, Mitsuyo, Dolai, Subhankar, He, Yu, Qin, Tairan, Liang, Tao, Zhu, Dan, Kang, Youhou, Liu, Yunfeng, Kauppi, Maria, Xie, Li, Wan, Wilson C.Y, Bin, Na-Rhum, Sugita, Shuzo, Olkkonen, Vesa M, Takahashi, Noriko, Kasai, Haruo, Gaisano, Herbert Y
Published in Diabetes (New York, N.Y.) (01.07.2013)
Published in Diabetes (New York, N.Y.) (01.07.2013)
Get full text
Journal Article
Cab45b, a Munc18b-interacting Partner, Regulates Exocytosis in Pancreatic β-Cells
Yi Zhang, You-hou Kang, Nathan Chang, Patrick P. L. Lam, Yunfeng Liu, Vesa M. Olkkonen, Herbert Y. Gaisano
Published in The Journal of biological chemistry (31.07.2009)
Published in The Journal of biological chemistry (31.07.2009)
Get full text
Journal Article
Alcohol-induced protein kinase Calpha phosphorylation of Munc18c in carbachol-stimulated acini causes basolateral exocytosis
Cosen-Binker, Laura I, Lam, Patrick P L, Binker, Marcelo G, Gaisano, Herbert Y
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2007)
Get more information
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2007)
Journal Article
Deletion of Fas in the pancreatic {beta}-cells leads to enhanced insulin secretion
Choi, Diana, Radziszewska, Anna, Schroer, Stephanie A, Liadis, Nicole, Liu, Yunfeng, Zhang, Yi, Lam, Patrick P. L, Sheu, Laura, Hao, Zhenyue, Gaisano, Herbert Y, Woo, Minna
Published in American journal of physiology: endocrinology and metabolism (01.12.2009)
Published in American journal of physiology: endocrinology and metabolism (01.12.2009)
Get full text
Journal Article
Alcohol/Cholecystokinin-evoked Pancreatic Acinar Basolateral Exocytosis Is Mediated by Protein Kinase Cα Phosphorylation of Munc18c
Laura I. Cosen-Binker, Patrick P. L. Lam, Marcelo G. Binker, Joseph Reeve, Stephen Pandol, Herbert Y. Gaisano
Published in The Journal of biological chemistry (27.04.2007)
Published in The Journal of biological chemistry (27.04.2007)
Get full text
Journal Article
VAMP8 Deletion Delays the Onset of Streptozotocin-Induced Hyperglycemia
Liu, Yunfeng, MD, Zhang, Yi, PhD, Zhu, Dan, PhD, Cai, Erica P., MSc, Choi, Diana, PhD, Schroer, Stephanie A., BSc, Lam, Patrick P.L., PhD, Kang, Youhou, PhD, Woo, Minna, MD, PhD, Gaisano, Herbert Y., MD
Published in Canadian journal of diabetes (01.10.2012)
Published in Canadian journal of diabetes (01.10.2012)
Get full text
Journal Article
Disruption of Pancreatic β-Cell Lipid Rafts Modifies Kv2.1 Channel Gating and Insulin Exocytosis
Fuzhen Xia, Xiaodong Gao, Edwin Kwan, Patrick P. L. Lam, Lillian Chan, Keiyan Sy, Laura Sheu, Michael B. Wheeler, Herbert Y. Gaisano, Robert G. Tsushima
Published in The Journal of biological chemistry (04.06.2004)
Published in The Journal of biological chemistry (04.06.2004)
Get full text
Journal Article