The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain development in youth
Satterthwaite, Theodore D., Connolly, John J., Ruparel, Kosha, Calkins, Monica E., Jackson, Chad, Elliott, Mark A., Roalf, David R., Hopson, Ryan, Prabhakaran, Karthik, Behr, Meckenzie, Qiu, Haijun, Mentch, Frank D., Chiavacci, Rosetta, Sleiman, Patrick M.A., Gur, Ruben C., Hakonarson, Hakon, Gur, Raquel E.
Published in NeuroImage (Orlando, Fla.) (01.01.2016)
Published in NeuroImage (Orlando, Fla.) (01.01.2016)
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Application of deep learning algorithm on whole genome sequencing data uncovers structural variants associated with multiple mental disorders in African American patients
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Published in Molecular psychiatry (01.03.2022)
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Phenome-wide association studies across large population cohorts support drug target validation
Diogo, Dorothée, Tian, Chao, Franklin, Christopher S., Alanne-Kinnunen, Mervi, March, Michael, Spencer, Chris C. A., Vangjeli, Ciara, Weale, Michael E., Mattsson, Hannele, Kilpeläinen, Elina, Sleiman, Patrick M. A., Reilly, Dermot F., McElwee, Joshua, Maranville, Joseph C., Chatterjee, Arnaub K., Bhandari, Aman, Nguyen, Khanh-Dung H., Estrada, Karol, Reeve, Mary-Pat, Hutz, Janna, Bing, Nan, John, Sally, MacArthur, Daniel G., Salomaa, Veikko, Ripatti, Samuli, Hakonarson, Hakon, Daly, Mark J., Palotie, Aarno, Hinds, David A., Donnelly, Peter, Fox, Caroline S., Day-Williams, Aaron G., Plenge, Robert M., Runz, Heiko
Published in Nature communications (16.10.2018)
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Identification of Four Novel Loci in Asthma in European American and African American Populations
Almoguera, Berta, Vazquez, Lyam, Mentch, Frank, Connolly, John, Pacheco, Jennifer A, Sundaresan, Agnes S, Peissig, Peggy L, Linneman, James G, McCarty, Catherine A, Crosslin, David, Carrell, David S, Lingren, Todd, Namjou-Khales, Bahram, Harley, John B, Larson, Eric, Jarvik, Gail P, Brilliant, Murray, Williams, Marc S, Kullo, Iftikhar J, Hysinger, Erik B, Sleiman, Patrick M A, Hakonarson, Hakon
Published in American journal of respiratory and critical care medicine (15.02.2017)
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Considering spatial and temporal scale in landscape-genetic studies of gene flow
Anderson, Corey Devin, Epperson, Bryan K, Fortin, Marie-Josee, Holderegger, Rolf, James, Patrick M.A, Rosenberg, Michael S, Scribner, Kim T, Spear, Stephen
Published in Molecular ecology (01.09.2010)
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Identification of novel loci in obstructive sleep apnea in European American and African American children
Quinlan, Courtney M, Chang, Xiao, March, Michael, Mentch, Frank D, Qu, Hui-Qi, Liu, Yichuan, Glessner, Joseph, Sleiman, Patrick M A, Hakonarson, Hakon
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Published in Sleep (New York, N.Y.) (11.03.2024)
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ParseCNV2: efficient sequencing tool for copy number variation genome-wide association studies
Glessner, Joseph T, Li, Jin, Liu, Yichuan, Khan, Munir, Chang, Xiao, Sleiman, Patrick M A, Hakonarson, Hakon
Published in European journal of human genetics : EJHG (01.03.2023)
Published in European journal of human genetics : EJHG (01.03.2023)
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Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
Müller, Ulrich, Schellenberg, Gerard D, Höglinger, Günter U, Melhem, Nadine M, Dickson, Dennis W, Sleiman, Patrick M A, Wang, Li-San, Klei, Lambertus, Rademakers, Rosa, de Silva, Rohan, Litvan, Irene, Riley, David E, van Swieten, John C, Heutink, Peter, Wszolek, Zbigniew K, Uitti, Ryan J, Vandrovcova, Jana, Hurtig, Howard I, Gross, Rachel G, Maetzler, Walter, Goldwurm, Stefano, Tolosa, Eduardo, Borroni, Barbara, Pastor, Pau, Cantwell, Laura B, Han, Mi Ryung, Dillman, Allissa, van der Brug, Marcel P, Gibbs, J Raphael, Cookson, Mark R, Hernandez, Dena G, Singleton, Andrew B, Farrer, Matthew J, Yu, Chang-En, Golbe, Lawrence I, Revesz, Tamas, Hardy, John, Lees, Andrew J, Devlin, Bernie, Hakonarson, Hakon
Published in Nature genetics (01.07.2011)
Published in Nature genetics (01.07.2011)
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Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder
Elia, Josephine, Glessner, Joseph T, Wang, Kai, Takahashi, Nagahide, Shtir, Corina J, Hadley, Dexter, Sleiman, Patrick M A, Zhang, Haitao, Kim, Cecilia E, Robison, Reid, Lyon, Gholson J, Flory, James H, Bradfield, Jonathan P, Imielinski, Marcin, Hou, Cuiping, Frackelton, Edward C, Chiavacci, Rosetta M, Sakurai, Takeshi, Rabin, Cara, Middleton, Frank A, Thomas, Kelly A, Garris, Maria, Mentch, Frank, Freitag, Christine M, Steinhausen, Hans-Christoph, Todorov, Alexandre A, Reif, Andreas, Rothenberger, Aribert, Franke, Barbara, Mick, Eric O, Roeyers, Herbert, Buitelaar, Jan, Lesch, Klaus-Peter, Banaschewski, Tobias, Ebstein, Richard P, Mulas, Fernando, Oades, Robert D, Sergeant, Joseph, Sonuga-Barke, Edmund, Renner, Tobias J, Romanos, Marcel, Romanos, Jasmin, Warnke, Andreas, Walitza, Susanne, Meyer, Jobst, Pálmason, Haukur, Seitz, Christiane, Loo, Sandra K, Smalley, Susan L, Biederman, Joseph, Kent, Lindsey, Asherson, Philip, Anney, Richard J L, Gaynor, J William, Shaw, Philip, Devoto, Marcella, White, Peter S, Grant, Struan F A, Buxbaum, Joseph D, Rapoport, Judith L, Williams, Nigel M, Nelson, Stanley F, Faraone, Stephen V, Hakonarson, Hakon
Published in Nature genetics (01.01.2012)
Published in Nature genetics (01.01.2012)
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Rare copy number variants in over 100,000 European ancestry subjects reveal multiple disease associations
Li, Yun Rose, Glessner, Joseph T., Coe, Bradley P., Li, Jin, Mohebnasab, Maede, Chang, Xiao, Connolly, John, Kao, Charlly, Wei, Zhi, Bradfield, Jonathan, Kim, Cecilia, Hou, Cuiping, Khan, Munir, Mentch, Frank, Qiu, Haijun, Bakay, Marina, Cardinale, Christopher, Lemma, Maria, Abrams, Debra, Bridglall-Jhingoor, Andrew, Behr, Meckenzie, Harrison, Shanell, Otieno, George, Thomas, Alexandria, Wang, Fengxiang, Chiavacci, Rosetta, Wu, Lawrence, Hadley, Dexter, Goldmuntz, Elizabeth, Elia, Josephine, Maris, John, Grundmeier, Robert, Devoto, Marcella, Keating, Brendan, March, Michael, Pellagrino, Renata, Grant, Struan F. A., Sleiman, Patrick M. A., Li, Mingyao, Eichler, Evan E., Hakonarson, Hakon
Published in Nature communications (14.01.2020)
Published in Nature communications (14.01.2020)
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MONTAGE: a new tool for high-throughput detection of mosaic copy number variation
Glessner, Joseph T, Chang, Xiao, Liu, Yichuan, Li, Jin, Khan, Munir, Wei, Zhi, Sleiman, Patrick M A, Hakonarson, Hakon
Published in BMC genomics (24.02.2021)
Published in BMC genomics (24.02.2021)
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GWAS identifies four novel eosinophilic esophagitis loci
Sleiman, Patrick M. A., Wang, Mei-Lun, Cianferoni, Antonella, Aceves, Seema, Gonsalves, Nirmala, Nadeau, Kari, Bredenoord, Albert J., Furuta, Glenn T., Spergel, Jonathan M., Hakonarson, Hakon
Published in Nature communications (19.11.2014)
Published in Nature communications (19.11.2014)
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Variants of DENND1B Associated with Asthma in Children
Sleiman, Patrick M.A, Flory, James, Imielinski, Marcin, Bradfield, Jonathan P, Annaiah, Kiran, Willis-Owen, Saffron A.G, Wang, Kai, Rafaels, Nicholas M, Michel, Sven, Bonnelykke, Klaus, Zhang, Haitao, Kim, Cecilia E, Frackelton, Edward C, Glessner, Joseph T, Hou, Cuiping, Otieno, F. George, Santa, Erin, Thomas, Kelly, Smith, Ryan M, Glaberson, Wendy R, Garris, Maria, Chiavacci, Rosetta M, Beaty, Terri H, Ruczinski, Ingo, Orange, Jordan M, Allen, Julian, Spergel, Jonathan M, Grundmeier, Robert, Mathias, Rasika A, Christie, Jason D, von Mutius, Erika, Cookson, William O.C, Kabesch, Michael, Moffatt, Miriam F, Grunstein, Michael M, Barnes, Kathleen C, Devoto, Marcella, Magnusson, Mark, Li, Hongzhe, Grant, Struan F.A, Bisgaard, Hans, Hakonarson, Hakon
Published in The New England journal of medicine (07.01.2010)
Published in The New England journal of medicine (07.01.2010)
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Coding for Life: Designing a Platform for Projecting and Protecting Global Biodiversity
Urban, Mark C, Travis, Justin M J, Zurell, Damaris, Thompson, Patrick L, Synes, Nicholas W, Scarpa, Alice, Peres-Neto, Pedro R, Malchow, Anne-Kathleen, James, Patrick M A, Gravel, Dominique, De Meester, Luc, Brown, Calum, Bocedi, Greta, Albert, Cécile H, Gonzalez, Andrew, Hendry, Andrew P
Published in Bioscience (01.01.2022)
Published in Bioscience (01.01.2022)
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NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients
March, Michael E., Gutierrez-Uzquiza, Alvaro, Snorradottir, Asbjorg Osk, Matsuoka, Leticia S., Balvis, Noelia Fonseca, Gestsson, Thorgeir, Nguyen, Kenny, Sleiman, Patrick M. A., Kao, Charlly, Isaksson, Helgi J., Bragason, Birkir Thor, Olafsson, Elias, Palsdottir, Astridur, Hakonarson, Hakon
Published in Nature communications (23.03.2021)
Published in Nature communications (23.03.2021)
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Burden of rare coding variants reveals genetic heterogeneity between obese and non-obese asthma patients in the African American population
Liu, Yichuan, Qu, Hui-Qi, Qu, Jingchun, Chang, Xiao, Mentch, Frank D, Nguyen, Kenny, Tian, Lifeng, Glessner, Joseph, Sleiman, Patrick M A, Hakonarson, Hakon
Published in Respiratory research (06.05.2022)
Published in Respiratory research (06.05.2022)
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Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease
Wang, Kai, Zhang, Haitao, Kugathasan, Subra, Annese, Vito, Bradfield, Jonathan P., Russell, Richard K., Sleiman, Patrick M.A., Imielinski, Marcin, Glessner, Joseph, Hou, Cuiping, Wilson, David C., Walters, Thomas, Kim, Cecilia, Frackelton, Edward C., Lionetti, Paolo, Barabino, Arrigo, Van Limbergen, Johan, Guthery, Stephen, Denson, Lee, Piccoli, David, Li, Mingyao, Dubinsky, Marla, Silverberg, Mark, Griffiths, Anne, Grant, Struan F.A., Satsangi, Jack, Baldassano, Robert, Hakonarson, Hakon
Published in American journal of human genetics (13.03.2009)
Published in American journal of human genetics (13.03.2009)
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An electronic health record (EHR) phenotype algorithm to identify patients with attention deficit hyperactivity disorders (ADHD) and psychiatric comorbidities
Slaby, Isabella, Hain, Heather S, Abrams, Debra, Mentch, Frank D, Glessner, Joseph T, Sleiman, Patrick M A, Hakonarson, Hakon
Published in Journal of neurodevelopmental disorders (11.06.2022)
Published in Journal of neurodevelopmental disorders (11.06.2022)
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Temporal variation in spatial genetic structure during population outbreaks: Distinguishing among different potential drivers of spatial synchrony
Larroque, Jeremy, Legault, Simon, Johns, Rob, Lumley, Lisa, Cusson, Michel, Renaut, Sébastien, Levesque, Roger C., James, Patrick M. A.
Published in Evolutionary applications (01.12.2019)
Published in Evolutionary applications (01.12.2019)
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