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Microsatellite instability-high colorectal cancer patient-derived xenograft models for cancer immunity research
Suto, Hirotaka, Funakoshi, Yohei, Nagatani, Yoshiaki, Imamura, Yoshinori, Toyoda, Masanori, Kiyota, Naomi, Matsumoto, Hisayuki, Tanaka, Shinwa, Takai, Ryo, Hasegawa, Hiroshi, Yamashita, Kimihiro, Matsuda, Takeru, Kakeji, Yoshihiro, Minami, Hironobu
Published in Journal of cancer research and therapeutics (01.10.2021)
Published in Journal of cancer research and therapeutics (01.10.2021)
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Journal Article
Cytotoxic T Lymphocytes Regenerated from iPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model
Kashima, Soki, Maeda, Takuya, Masuda, Kyoko, Nagano, Seiji, Inoue, Takamitsu, Takeda, Masashi, Kono, Yuka, Kobayashi, Takashi, Saito, Shigeyoshi, Higuchi, Takahiro, Ichise, Hiroshi, Kobayashi, Yuka, Iwaisako, Keiko, Terada, Koji, Agata, Yasutoshi, Numakura, Kazuyuki, Saito, Mitsuru, Narita, Shintaro, Yasukawa, Masaki, Ogawa, Osamu, Habuchi, Tomonori, Kawamoto, Hiroshi
Published in iScience (24.04.2020)
Published in iScience (24.04.2020)
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Journal Article
Molecular events in neuroendocrine prostate cancer development
Wang, Yong, Wang, Yu, Ci, Xinpei, Choi, Stephen Y. C., Crea, Francesco, Lin, Dong, Wang, Yuzhuo
Published in Nature reviews. Urology (01.10.2021)
Published in Nature reviews. Urology (01.10.2021)
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Journal Article
Immunotherapy of Acute Myeloid Leukemia Enabled By Targeting of Pan-Cancer Molecular Patterns with a Novel Trispecific T Cell Engager
Varkey, Ashley, Bariana, Manpreet, Cassella, Elena, Anuncio, Shaina, Batistick, Mark, Sequeira, Sonia, Ahmed, Mahiuddin, Zakrzewski, Johannes
Published in Blood (05.11.2024)
Published in Blood (05.11.2024)
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Journal Article
Abstract LB-080: Imprime PGG, a β-glucan PAMP (pathogen-associated molecular pattern) activates the direct killing functions of innate immune cells in concert with tumor targeting antibodies
Leonardo, Steven M., Fulton, Ross B., Gorden, Keith B., Fraser, Katy, Harrison, Ben, Kangas, Takashi, Jonas, Adria, Yokoyama, Yumi, Ottoson, Nadine, Bose, Nandita, Graff, Jeremy R.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase
Baltgalvis, Kristen A., Lamb, Kelsey N., Symons, Kent T., Wu, Chu-Chiao, Hoffman, Melissa A., Snead, Aaron N., Song, Xiaodan, Glaza, Thomas, Kikuchi, Shota, Green, Jason C., Rogness, Donald C., Lam, Betty, Rodriguez-Aguirre, Maria E., Woody, David R., Eissler, Christie L., Rodiles, Socorro, Negron, Seth M., Bernard, Steffen M., Tran, Eileen, Pollock, Jonathan, Tabatabaei, Ali, Contreras, Victor, Williams, Heather N., Pastuszka, Martha K., Sigler, John J., Pettazzoni, Piergiorgio, Rudolph, Markus G., Classen, Moritz, Brugger, Doris, Claiborne, Christopher, Plancher, Jean-Marc, Cuartas, Isabel, Seoane, Joan, Burgess, Laurence E., Abraham, Robert T., Weinstein, David S., Simon, Gabriel M., Patricelli, Matthew P., Kinsella, Todd M.
Published in Nature (London) (09.05.2024)
Published in Nature (London) (09.05.2024)
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Journal Article
Targeting Krasg12c‐mutant cancer with a mutation‐specific inhibitor
Christensen, J. G., Olson, P., Briere, T., Wiel, C., Bergo, M. O.
Published in Journal of internal medicine (01.08.2020)
Published in Journal of internal medicine (01.08.2020)
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Journal Article
Found in Translation: Maximizing the Clinical Relevance of Nonclinical Oncology Studies
Spilker, Mary E., Chen, Xiaoying, Visswanathan, Ravi, Vage, Chandra, Yamazaki, Shinji, Li, Gang, Lucas, Judy, Bradshaw-Pierce, Erica L., Vicini, Paolo
Published in Clinical cancer research (15.02.2017)
Published in Clinical cancer research (15.02.2017)
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Journal Article
A Phase 1, Open-Label, Multicenter, Dose-Escalation Study of Sgr-1505 As Monotherapy in Subjects with Mature B-Cell Malignancies
Olszewski, Adam, Kahn, David, Yoo, Brian, Tan, Joanne BL, Gupta, Vipul K, Schuck, Edgar, Nie, Zhe, Krilov, Goran, Wright, D. Hamish, Weiss, Daniel, Lachowicz, Jean, Akinsanya, Karen, Yin, Wu
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
An investigator-initiated trial to evaluate safety and tolerability of YSCH-01 in patients with recurrent glioblastoma
Zhang, Kang-jian, Wu, Zanyi, Fang, Xian-long, Cao, Xue-ping, Jiang, Shan, Shi, Zhi-feng, Liu, Yanqiu, Li, Ruimei, Kang, De-zhi
Published in Journal of clinical oncology (10.08.2024)
Published in Journal of clinical oncology (10.08.2024)
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Journal Article
An open-label, multicenter phase 1 study to characterize safety, tolerability, preliminary antitumor activity, and pharmacokinetics of VIP236 monotherapy in patients with advanced cancer
Stein, Brian N., Coward, Jermaine, Sharma, Sunil, Johnson, Amy J., Birkett, Joseph, Huang, Xin, Frigault, Melanie M., Lerchen, Hans-georg, Stelte-Ludwig, Beatrix, Navarro, Tasheda, Peck, Jim, Gross, Wyatt, Izumi, Raquel, Hamdy, Ahmed M., Rodriguez Rivera, Ildefonso
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Journal Article
Abstract CT249: A study to evaluate the safety and tolerability of the covalent phosphoinositide-3-kinase (PI3K)-alpha Inhibitor, TOS-358, in adult subjects with select solid tumors
Fakih, Marwan, Sohal, Davendra P., Hafez, Navid, Berlin, Jordan D., Hari, Kimberly, Trifan, Ovid C.
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Journal Article
CTNI-01. A PHASE 1-2 CLINICAL TRIAL OF EO1001 (APL-122), A NOVEL IRREVERSIBLE PAN-ERBB INHIBITOR WITH PROMISING BRAIN PENETRATION
Frentzas, Sophia, Richardson, Gary, Bacha, Jeffrey, Kanekal, Sarath, Sankar, Neil, Shen, Wang, Redkar, Sanjeev, Lai, Chinglin, Yu, Peony, Nisbet, Ian, Skoff, Kathy, Wheeler, Helen, Pedersen, Harry, Zhong, Wang Zhen, Brown, Dennis
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
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Journal Article
Targeting Kras g12c ‐mutant cancer with a mutation‐specific inhibitor
Christensen, J. G., Olson, P., Briere, T., Wiel, C., Bergo, M. O.
Published in Journal of internal medicine (01.08.2020)
Published in Journal of internal medicine (01.08.2020)
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Journal Article
TRLS-06. A Phase 1–2 clinical trial of EO1001 (APL-122), a novel irreversible pan-ErbB inhibitor with promising brain penetration
Frentzas, Sophia, Richardson, Gary, Bacha, Jeffrey, Kanekal, Sarath, Sankar, Neil, Shen, Wang, Redkar, Sanjeev, Lai, Chinglin, Yu, Peony, Nisbet, Ian, Skoff, Kathy, Wheeler, Helen, Pedersen, Harry, Zhong, Wang Zhen, Brown, Dennis
Published in Neuro-oncology advances (09.08.2021)
Published in Neuro-oncology advances (09.08.2021)
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Journal Article
PEPN2312: A Pediatric Early Phase Clinical Trials Network (PEP-CTN) Phase 1 Trial of Imetelstat with Fludarabine/Cytarabine in Pediatric Patients with Relapsed/Refractory AML, MDS, or JMML
Stevens, Alexandra McLean, O'Brien, Maureen M., Liu, Xiaowei, Minard, Charles G, Militano, Olga, Reid, Joel M, Navada, Shyamala, Cooper, Todd M, Tasian, Sarah K., Fox, Elizabeth, Weigel, Brenda J.
Published in Blood (05.11.2024)
Published in Blood (05.11.2024)
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Journal Article
Abstract P1-18-17: Phase I study of cfi-402257, an oral ttk inhibitor, in patients with advanced solid tumors with breast cancer expansion cohorts
Hilton, John, Renouf, Daniel J, Cescon, David W, Hansen, Aaron R, Razak, Albiruni RA, Stayner, Lee-Anne, Denny, Trisha, Fletcher, Graham, Mak, Tak W, Bray, Mark, Bedard, Philippe L
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Journal Article