GBT021601 improves red blood cell health and the pathophysiology of sickle cell disease in a murine model
Dufu, Kobina, Alt, Carsten, Strutt, Steven, Partridge, James, Tang, Tzechiang, Siu, Vincent, Liao‐Zou, Hilary, Rademacher, Peter, Williams, Alexander T., Muller, Cynthia R., Geng, Xin, Pochron, Mira Patel, Dang, Annie Nguyen, Cabrales, Pedro, Li, Zhe, Oksenberg, Donna, Cathers, Brian E.
Published in British journal of haematology (01.07.2023)
Published in British journal of haematology (01.07.2023)
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Journal Article
Predictive Biomarker Analysis from the GBT021601 Survival Study in Townes Sickle Mice
Pochron, Mira Patel, Sun, Jiaxin, Potdar, Alka A, Alt, Carsten, DeGuzman, Francis, Connor, Michael W., Cathers, Brian, Dufu, Kobina, Archer, David R
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Evaluation of GBT021601 As a Therapeutic Agent to Restore Bone Marrow Health and Effective Erythropoiesis in a Sickle Mouse Model
Hernandez, Britney, Priyadarshini, Anupama, Kostamo, Zachary, Zhang, Yankai, Patel, Ashwin P, Pendergast, Michael A, Jupelli, Madhulika, Huang, Heli, Nguyen Dang, Annie, Pochron, Mira Patel, Dufu, Kobina, Sheehan, Vivien A
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Preliminary Results from a Multicenter Phase 2/3 Study of Next-Generation HbS Polymerization Inhibitor GBT021601 for the Treatment of Patients with Sickle Cell Disease
Saraf, Santosh L., Abdullahi, Shehu Umar, Akinsete, Adeseye Michael, Fasola, Foluke A, Idowu, Modupe, Pennington, Sharon, Ershler, William B, Stagg, Marshall Patrick, Chin, Wai, Zimmerman, Eric, Adenola, Adeyemi, Pochron, Mira Patel, Lisbon, Eleanor A
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Preliminary Pharmacodynamic Results from a Multicenter Phase 2/3 Study of Next-Generation HbS Polymerization Inhibitor GBT021601 for the Treatment of Patients with Sickle Cell Disease
Pochron, Mira Patel, Akinsete, Adeseye Michael, Abdullahi, Shehu Umar, Fasola, Foluke A, Idowu, Modupe, Pennington, Sharon, Ershler, William B, Stagg, Marshall Patrick, Fields, Earl, Sterling, Morgan, Chonat, Satheesh, Paliwal, Yuvika, Kong, Karena, Archer, David R, Adenola, Adeyemi, Lisbon, Eleanor A
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article