Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy
Hoogenboezem, Ella N., Patel, Shrusti S., Lo, Justin H., Cavnar, Ashley B., Babb, Lauren M., Francini, Nora, Gbur, Eva F., Patil, Prarthana, Colazo, Juan M., Michell, Danielle L., Sanchez, Violeta M., McCune, Joshua T., Ma, Jinqi, DeJulius, Carlisle R., Lee, Linus H., Rosch, Jonah C., Allen, Ryan M., Stokes, Larry D., Hill, Jordan L., Vickers, Kasey C., Cook, Rebecca S., Duvall, Craig L.
Published in Nature communications (21.02.2024)
Published in Nature communications (21.02.2024)
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Journal Article
Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing
Patel, Shrusti S., Hoogenboezem, Ella N., Yu, Fang, DeJulius, Carlisle R., Fletcher, R. Brock, Sorets, Alex G., Cherry, Fiona K., Lo, Justin H., Bezold, Mariah G., Francini, Nora, d’Arcy, Richard, Brasuell, Jordan E., Cook, Rebecca S., Duvall, Craig L.
Published in Biomaterials (01.06.2023)
Published in Biomaterials (01.06.2023)
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Journal Article
Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes
Jackson, Meredith A., Bedingfield, Sean K., Yu, Fang, Stokan, Mitchell E., Miles, Rachel E., Curvino, Elizabeth J., Hoogenboezem, Ella N., Bonami, Rachel H., Patel, Shrusti S., Kendall, Peggy L., Giorgio, Todd D., Duvall, Craig L.
Published in Biomaterials (01.02.2019)
Published in Biomaterials (01.02.2019)
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Journal Article
Nonviral In Vivo Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles
Fletcher, R. Brock, Stokes, Larry D., Kelly, Isom B., Henderson, Katelyn M., Vallecillo-Viejo, Isabel C., Colazo, Juan M., Wong, Benjamin V., Yu, Fang, d’Arcy, Richard, Struthers, Morgan N., Evans, Brian C., Ayers, Jacob, Castanon, Matthew, Weirich, Michael J., Reilly, Sarah K., Patel, Shrusti S., Ivanova, Yoanna I., Silvera Batista, Carlos A., Weiss, Sharon M., Gersbach, Charles A., Brunger, Jonathan M., Duvall, Craig L.
Published in ACS nano (12.09.2023)
Published in ACS nano (12.09.2023)
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Journal Article
Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers
Jackson, Meredith A., Patel, Shrusti S., Yu, Fang, Cottam, Matthew A., Glass, Evan B., Hoogenboezem, Ella N., Fletcher, R. Brock, Dollinger, Bryan R., Patil, Prarthana, Liu, Danielle D., Kelly, Isom B., Bedingfield, Sean K., King, Allyson R., Miles, Rachel E., Hasty, Alyssa M., Giorgio, Todd D., Duvall, Craig L.
Published in Biomaterials (01.01.2021)
Published in Biomaterials (01.01.2021)
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Journal Article
Left–right analysis of mammary gland development in retinoid X receptor-α+/− mice
Robichaux, Jacqulyne P., Fuseler, John W., Patel, Shrusti S., Kubalak, Steven W., Hartstone-Rose, Adam, Ramsdell, Ann F.
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19.12.2016)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19.12.2016)
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Journal Article
Structural Optimization of siRNA Conjugates for Albumin Binding Achieves Effective MCL1-Targeted Cancer Therapy
Hoogenboezem, Ella N, Patel, Shrusti S, Cavnar, Ashley B, Lo, Justin H, Babb, Lauren M, Francini, Nora, Patil, Prarthana, Colazo, Juan M, Michell, Danielle L, Sanchez, Violeta M, McCune, Joshua T, Ma, Jinqi, DeJulius, Carlisle R, Lee, Linus H, Rosch, Jonah C, Allen, Ryan M, Stokes, Larry D, Hill, Jordan L, Vickers, Kasey C, Cook, Rebecca S, Duvall, Craig L
Published in bioRxiv (15.02.2023)
Published in bioRxiv (15.02.2023)
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Left–right analysis of mammary gland development in retinoid X receptor-α+/−mice
Robichaux, Jacqulyne P., Fuseler, John W., Patel, Shrusti S., Kubalak, Steven W., Hartstone-Rose, Adam, Ramsdell, Ann F.
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19.12.2016)
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Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19.12.2016)
Journal Article
Abstract 2706: Therapeutic silencing of Rictor using siRNA nanoparticles to selectively block mTORC2 signaling in triple negative breast cancer
Patel, Shrusti S., Hoogenboezem, Ella N., Yu, Fang, Sorets, Alex G., Cherry, Fiona K., Lo, Justin H., Francini, Nora, d'Arcy, Richard A., Cook, Rebecca S., Duvall, Craig L.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Kupffer Cell Release of Platelet Activating Factor Drives Dose Limiting Toxicities of Nucleic Acid Nanocarriers
Jackson, Meredith A, Patel, Shrusti S, Yu, Fang, Cottam, Matthew A, Glass, Evan B, Dollinger, Bryan R, Hoogenboezem, Ella N, Patil, Prarthana, Liu, Danielle D, Kelly, Isom B, Bedingfield, Sean K, King, Allyson R, Miles, Rachel E, Hasty, Alyssa M, Giorgio, Todd D, Duvall, Craig L
Published in bioRxiv (12.02.2020)
Published in bioRxiv (12.02.2020)
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