Resistance to TRK inhibition mediated by convergent MAPK pathway activation
Cocco, Emiliano, Schram, Alison M., Kulick, Amanda, Misale, Sandra, Won, Helen H., Yaeger, Rona, Razavi, Pedram, Ptashkin, Ryan, Hechtman, Jaclyn F., Toska, Eneda, Cownie, James, Somwar, Romel, Shifman, Sophie, Mattar, Marissa, Selçuklu, S. Duygu, Samoila, Aliaksandra, Guzman, Sean, Tuch, Brian B., Ebata, Kevin, de Stanchina, Elisa, Nagy, Rebecca J., Lanman, Richard B., Houck-Loomis, Brian, Patel, Juber A., Berger, Michael F., Ladanyi, Marc, Hyman, David M., Drilon, Alexander, Scaltriti, Maurizio
Published in Nature medicine (01.09.2019)
Published in Nature medicine (01.09.2019)
Get full text
Journal Article
Gut microbiomes of wild great apes fluctuate seasonally in response to diet
Hicks, Allison L., Lee, Kerry Jo, Couto-Rodriguez, Mara, Patel, Juber, Sinha, Rohini, Guo, Cheng, Olson, Sarah H., Seimon, Anton, Seimon, Tracie A., Ondzie, Alain U., Karesh, William B., Reed, Patricia, Cameron, Kenneth N., Lipkin, W. Ian, Williams, Brent L.
Published in Nature communications (03.05.2018)
Published in Nature communications (03.05.2018)
Get full text
Journal Article
Tumor fraction-guided cell-free DNA profiling in metastatic solid tumor patients
Tsui, Dana W Y, Cheng, Michael L, Shady, Maha, Yang, Julie L, Stephens, Dennis, Won, Helen, Srinivasan, Preethi, Huberman, Kety, Meng, Fanli, Jing, Xiaohong, Patel, Juber, Hasan, Maysun, Johnson, Ian, Gedvilaite, Erika, Houck-Loomis, Brian, Socci, Nicholas D, Selcuklu, S Duygu, Seshan, Venkatraman E, Zhang, Hongxin, Chakravarty, Debyani, Zehir, Ahmet, Benayed, Ryma, Arcila, Maria, Ladanyi, Marc, Funt, Samuel A, Feldman, Darren R, Li, Bob T, Razavi, Pedram, Rosenberg, Jonathan, Bajorin, Dean, Iyer, Gopa, Abida, Wassim, Scher, Howard I, Rathkopf, Dana, Viale, Agnes, Berger, Michael F, Solit, David B
Published in Genome medicine (31.05.2021)
Published in Genome medicine (31.05.2021)
Get full text
Journal Article
Cell‐free DNA profiling in retinoblastoma patients with advanced intraocular disease: An MSKCC experience
Kothari, Prachi, Marass, Francesco, Yang, Julie L., Stewart, Caitlin M., Stephens, Dennis, Patel, Juber, Hasan, Maysun, Jing, Xiaohong, Meng, Fanli, Enriquez, Jeanette, Huberman, Kety, Viale, Agnes, Francis, Jasmine H., Berger, Michael F., Shukla, Neerav, Abramson, David H., Dunkel, Ira J., Tsui, Dana W.Y.
Published in Cancer medicine (Malden, MA) (01.09.2020)
Published in Cancer medicine (Malden, MA) (01.09.2020)
Get full text
Journal Article
Plasma DNA-based molecular diagnosis, prognostication, and monitoring of patients with EWSR1 fusion-positive sarcomas
Shukla, Neerav N, Patel, Juber A, Magnan, Heather, Zehir, Ahmet, You, Daoqi, Tang, Jiabin, Meng, Fanli, Samoila, Aliaksandra, Slotkin, Emily K, Ambati, Srikanth R, Chou, Alexander J, Wexler, Leonard H, Meyers, Paul A, Peerschke, Ellinor I, Viale, Agnes, Berger, Michael F, Ladanyi, Marc
Published in JCO precision oncology (01.01.2017)
Published in JCO precision oncology (01.01.2017)
Get more information
Journal Article
Utility of Serial cfDNA NGS for Prospective Genomic Analysis of Patients on a Phase I Basket Study
Smyth, Lillian M, Reichel, Jonathan B, Tang, Jiabin, Patel, Juber Ahamad A, Meng, Fanli, Selcuklu, Duygu S, Houck-Loomis, Brian, You, Daoqi, Samoila, Aliaksandra, Schiavon, Gaia, Li, Bob T, Razavi, Pedram, Piscuoglio, Salvatore, Reis-Filho, Jorge S, Taylor, Barry S, Baselga, José, Solit, David B, Hyman, David M, Berger, Michael F, Chandarlapaty, Sarat
Published in JCO precision oncology (08.01.2021)
Published in JCO precision oncology (08.01.2021)
Get more information
Journal Article
HER kinase inhibition in patients with HER2- and HER3-mutant cancers
Hyman, David M., Piha-Paul, Sarina A., Won, Helen, Rodon, Jordi, Saura, Cristina, Shapiro, Geoffrey I., Juric, Dejan, Quinn, David I., Moreno, Victor, Doger, Bernard, Mayer, Ingrid A., Boni, Valentina, Calvo, Emiliano, Loi, Sherene, Lockhart, Albert C., Erinjeri, Joseph P., Scaltriti, Maurizio, Ulaner, Gary A., Patel, Juber, Tang, Jiabin, Beer, Hannah, Selcuklu, S. Duygu, Hanrahan, Aphrothiti J., Bouvier, Nancy, Melcer, Myra, Murali, Rajmohan, Schram, Alison M., Smyth, Lillian M., Jhaveri, Komal, Li, Bob T., Drilon, Alexander, Harding, James J., Iyer, Gopa, Taylor, Barry S., Berger, Michael F., Cutler Jr, Richard E., Xu, Feng, Butturini, Anna, Eli, Lisa D., Mann, Grace, Farrell, Cynthia, Lalani, Alshad S., Bryce, Richard P., Arteaga, Carlos L., Meric-Bernstam, Funda, Baselga, José, Solit, David B.
Published in Nature (London) (08.02.2018)
Published in Nature (London) (08.02.2018)
Get full text
Journal Article
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS
Rose Brannon, A., Jayakumaran, Gowtham, Diosdado, Monica, Patel, Juber, Razumova, Anna, Hu, Yu, Meng, Fanli, Haque, Mohammad, Sadowska, Justyna, Murphy, Brian J., Baldi, Tessara, Johnson, Ian, Ptashkin, Ryan, Hasan, Maysun, Srinivasan, Preethi, Rema, Anoop Balakrishnan, Rijo, Ivelise, Agarunov, Aaron, Won, Helen, Perera, Dilmi, Brown, David N., Samoila, Aliaksandra, Jing, Xiaohong, Gedvilaite, Erika, Yang, Julie L., Stephens, Dennis P., Dix, Jenna-Marie, DeGroat, Nicole, Nafa, Khedoudja, Syed, Aijazuddin, Li, Alan, Lebow, Emily S., Bowman, Anita S., Ferguson, Donna C., Liu, Ying, Mata, Douglas A., Sharma, Rohit, Yang, Soo-Ryum, Bale, Tejus, Benhamida, Jamal K., Chang, Jason C., Dogan, Snjezana, Hameed, Meera R., Hechtman, Jaclyn F., Moung, Christine, Ross, Dara S., Vakiani, Efsevia, Vanderbilt, Chad M., Yao, JinJuan, Razavi, Pedram, Smyth, Lillian M., Chandarlapaty, Sarat, Iyer, Gopa, Abida, Wassim, Harding, James J., Krantz, Benjamin, O’Reilly, Eileen, Yu, Helena A., Li, Bob T., Rudin, Charles M., Diaz, Luis, Solit, David B., Arcila, Maria E., Ladanyi, Marc, Loomis, Brian, Tsui, Dana, Berger, Michael F., Zehir, Ahmet, Benayed, Ryma
Published in Nature communications (18.06.2021)
Published in Nature communications (18.06.2021)
Get full text
Journal Article
Standard-of-care systemic therapy with or without stereotactic body radiotherapy in patients with oligoprogressive breast cancer or non-small-cell lung cancer (Consolidative Use of Radiotherapy to Block [CURB] oligoprogression): an open-label, randomised, controlled, phase 2 study
Tsai, Chiaojung Jillian, Yang, Jonathan T, Shaverdian, Narek, Patel, Juber, Shepherd, Annemarie F, Eng, Juliana, Guttmann, David, Yeh, Randy, Gelblum, Daphna Y, Namakydoust, Azadeh, Preeshagul, Isabel, Modi, Shanu, Seidman, Andrew, Traina, Tiffany, Drullinsky, Pamela, Flynn, Jessica, Zhang, Zhigang, Rimner, Andreas, Gillespie, Erin F, Gomez, Daniel R, Lee, Nancy Y, Berger, Michael, Robson, Mark E, Reis-Filho, Jorge S, Riaz, Nadeem, Rudin, Charles M, Powell, Simon N, Berger, Michael, Bromberg, Jacqueline, Chen, Linda, Dang, Chau, Das, Jeeban P, Drullinsky, Pamela, Eng, Julianna, Flynn, Jessica, Gelblum, Daphna Y, Gillespie, Erin F, Girshman, Jeffrey, Gomez, Daniel R, Gucalp, Ayca, Guttmann, David, Hajj, Carla, Higginson, Daniel, Iqbal, Afsheen, Khan, Atif J, LaPlant, Quincey, Lee, Nancy Y, Mann, Justin M, Modi, Shanu, Namakydoust, Azadeh, Ng, Kenneth, Patel, Juber, Powell, Simon N, Preeshagul, Isabel, Reis-Filho, Jorge S, Reyngold, Marsha, Riaz, Nadeem, Rimner, Andreas, Robson, Mark E, Rudin, Charles M, Sanford, Rachel, Seidman, Andrew D, Shah, Ronak, Shaverdian, Narek, Shepherd, Annemarie F, Shin, Jacob Y, Sugarman, Steven, Traina, Tiffany A, Tsai, Chiaojung Jillian, Wu, Abraham J, Xu, Amy J, Yang, Jonathan T, Yeh, Randy, Zhang, Zhigang, Zhi, Wanqing
Published in The Lancet (British edition) (13.01.2024)
Published in The Lancet (British edition) (13.01.2024)
Get full text
Journal Article
Cell-free DNA analysis as a molecular tool to monitor response to immune checkpoint inhibition in endometrial cancer
Manning-Geist, Beryl, Patel, Juber Ahamad A, Marra, Antonio, Da Cruz Paula, Arnaud, Hanlon, Etta J, Abu-Rustum, Nadeem, Shah, Ronak H., Berger, Michael F., Hensley, Martee Leigh, Zamarin, Dmitriy, Weigelt, Britta, Friedman, Claire Frances
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
Get full text
Journal Article
Adenoid cystic carcinoma of the Bartholin's gland is underpinned by MYB- and MYBL1- rearrangements
Feinberg, Jacqueline, Da Cruz Paula, Arnaud, da Silva, Edaise M., Pareja, Fresia, Patel, Juber, Zhu, Yingjie, Selenica, Pier, Leitao, Mario M., Abu-Rustum, Nadeem R., Reis-Filho, Jorge S., Joehlin-Price, Amy, Weigelt, Britta
Published in Gynecologic oncology (01.06.2024)
Published in Gynecologic oncology (01.06.2024)
Get full text
Journal Article
High-Sensitivity Mutation Analysis of Cell-Free DNA for Disease Monitoring in Endometrial Cancer
Ashley, Charles W, Selenica, Pier, Patel, Juber, Wu, Michelle, Nincevic, Josip, Lakhman, Yulia, Zhou, Qin, Shah, Ronak H, Berger, Michael F, Da Cruz Paula, Arnaud, Brown, David N, Marra, Antonio, Iasonos, Alexia, Momeni-Boroujeni, Amir, Alektiar, Kaled M, Long Roche, Kara, Zivanovic, Oliver, Mueller, Jennifer J, Zamarin, Dmitriy, Broach, Vance A, Sonoda, Yukio, Leitao, Mario M, Friedman, Claire F, Jewell, Elizabeth, Reis-Filho, Jorge S, Ellenson, Lora H, Aghajanian, Carol, Abu-Rustum, Nadeem R, Cadoo, Karen, Weigelt, Britta
Published in Clinical cancer research (17.01.2023)
Published in Clinical cancer research (17.01.2023)
Get full text
Journal Article
Abstract PR07: MSI detection in plasma cfDNA: MSI as a marker of disease burden
Srinivasan, Preethi, Latham, Alicia, Patel, Zalak, Ziegler, John, Hasan, Maysun, Patel, Juber A., Johnson, Ian, Shah, Ronak, Meng, Fanli, Jing, Xiaohong, Tam, Grittney, Brannon, Rose, Cercek, Andrea, Zehir, Ahmet, Houck-Loomis, Brian, Tsui, Dana, Stadler, Zsofia, Berger, Michael F.
Published in Clinical cancer research (01.06.2020)
Published in Clinical cancer research (01.06.2020)
Get full text
Journal Article
Abstract 2516: A bioinformatics framework for high-sensitivity detection and monitoring of oncogenic gene fusions in plasma cfDNA
Patel, Juber, Hasan, Maysun, Meng, Fanli, Jing, Xiaohong, Tam, Grittney, Johnson, Ian, Zheng, Youyun, Bandlamudi, Chaitanya, Stewart, Caitlin, Won, Helen, Hampton, Oliver, Schram, Alison, Rosen, Ezra, Drilon, Alexander, Varghese, Anna, Hyman, David, Tsui, Dana, Houck-Loomis, Brian, Berger, Michael
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
Abstract 6243: Rapid autopsy reveals the interplay of tumor heterogeneity at genomic, transcriptomic, and spatial dimensions
Yao, Ning, Vanguri, Rami, Patel, Juber, Lihm, Jayon, Fisher, Andrew, Jarchum, Irene, Umeda, Shigeaki, Li, Hao, Ely, Scott, Hollmann, Travis, Iacobuzio-Donahue, Christine, Greenbaum, Benjamin
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Non-invasive detection of acquired resistance to FGFR inhibition in patients with cholangiocarcinoma harboring FGFR2 alterations
Varghese, Anna M., Patel, Juber Ahamad A, Janjigian, Yelena Yuriy, Meng, Fanli, Selcuklu, S Duygu, Zimel, Catherine, Hyman, David Michael, Iyer, Gopa, Houck-Loomis, Brian, Abou-Alfa, Ghassan K., Berger, Michael F., Lowery, Maeve Aine
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
Get full text
Journal Article
Abstract PR08: Validation and clinical implementation of MSK-ACCESS, an ultra-deep sequencing assay for noninvasive somatic mutation profiling
Brannon, A. Rose, Jayakumaran, Gowtham, Diosdado, Monica, Hu, Yu, Razumova, Anna, Meng, Fanli, Lebow, Emily, Patel, Juber, Johnson, Ian, Srinivasan, Preethi, Hasan, Maysun, Dix, Jenna-marie, Syed, Aijazuddin, Houck-Loomis, Brian, Li, Bob T., Rudin, Charles, Solit, David, Ladanyi, Marc, Arcila, Maria, Tsui, Dana, Zehir, Ahmet, Berger, Michael, Benayed, Ryma
Published in Clinical cancer research (01.06.2020)
Published in Clinical cancer research (01.06.2020)
Get full text
Journal Article
Noninvasive Detection of Polyclonal Acquired Resistance to FGFR Inhibition in Patients With Cholangiocarcinoma Harboring FGFR2 Alterations
Varghese, Anna M, Patel, Juber, Janjigian, Yelena Y, Meng, Fanli, Selcuklu, S Duygu, Iyer, Gopakumar, Houck-Loomis, Brian, Harding, James J, O'Reilly, Eileen M, Abou-Alfa, Ghassan K, Lowery, Maeve A, Berger, Michael F
Published in JCO precision oncology (2021)
Published in JCO precision oncology (2021)
Get more information
Journal Article
Abstract 5598: Development and optimization of a comprehensive high-sensitivity NGS cancer assay and bioinformatics pipeline for plasma cfDNA profiling
Patel, Juber, Hasan, Maysun, Meng, Fanli, Jing, Xiaohong, Perera, Dilmi, Reichel, Jonathan, Gedvilaite, Erika, Yang, Julie, Shady, Maha, Raj, Sandeep, Srinivasan, Preethi, Johnson, Ian, Wang, Jiashi, Jarosz, Mirna, Samoila, Aliaksandra, Viale, Agnes, Li, Bob, Razavi, Pedram, Tsui, Dana, Berger, Michael
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article
Abstract 3656: Detecting MSI in plasma: Implications for early detection of lynch associated tumors
Srinivasan, Preethi, Tran, Christina, Reichel, Jonathan, Patel, Juber Ahamad, Hasan, Maysun, Meng, Fanli, Jing, Xiaohong, Middha, Sumit, Zehir, Ahmet, Yaeger, Rona D., Reidy, Diane, Tsui, Dana, Stadler, Zsofia, Berger, Michael F.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article