Biochemical and pharmacological characterization of the human lymphocyte antigen B-associated transcript 5 (BAT5/ABHD16A)
Savinainen, Juha R, Patel, Jayendra Z, Parkkari, Teija, Navia-Paldanius, Dina, Marjamaa, Joona J T, Laitinen, Tuomo, Nevalainen, Tapio, Laitinen, Jarmo T
Published in PloS one (07.10.2014)
Published in PloS one (07.10.2014)
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Repurposing the Sphingosine-1-Phosphate Receptor Modulator Etrasimod as an Antibacterial Agent Against Gram-Positive Bacteria
Zore, Matej, Gilbert-Girard, Shella, San-Martin-Galindo, Paola, Reigada, Inés, Hanski, Leena, Savijoki, Kirsi, Fallarero, Adyary, Yli-Kauhaluoma, Jari, Patel, Jayendra Z.
Published in Frontiers in microbiology (06.06.2022)
Published in Frontiers in microbiology (06.06.2022)
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Journal Article
Synthesis and Biological Evaluation of Fingolimod Derivatives as Antibacterial Agents
Zore, Matej, Gilbert-Girard, Shella, Reigada, Inés, Patel, Jayendra Z, Savijoki, Kirsi, Fallarero, Adyary, Yli-Kauhaluoma, Jari
Published in ACS omega (20.07.2021)
Published in ACS omega (20.07.2021)
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Journal Article
Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL)
Korhonen, Jani, Kuusisto, Anne, van Bruchem, John, Patel, Jayendra Z., Laitinen, Tuomo, Navia-Paldanius, Dina, Laitinen, Jarmo T., Savinainen, Juha R., Parkkari, Teija, Nevalainen, Tapio J.
Published in Bioorganic & medicinal chemistry (01.12.2014)
Published in Bioorganic & medicinal chemistry (01.12.2014)
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Journal Article
Food-Grade Bacteria Combat Pathogens by Blocking AHL-Mediated Quorum Sensing and Biofilm Formation
Savijoki, Kirsi, San-Martin-Galindo, Paola, Pitkänen, Katriina, Edelmann, Minnamari, Sillanpää, Annika, van der Velde, Cim, Miettinen, Ilkka, Patel, Jayendra Z, Yli-Kauhaluoma, Jari, Parikka, Mataleena, Fallarero, Adyary, Varmanen, Pekka
Published in Foods (24.12.2022)
Published in Foods (24.12.2022)
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Journal Article
Combined Effect of Naturally-Derived Biofilm Inhibitors and Differentiated HL-60 Cells in the Prevention of Staphylococcus aureus Biofilm Formation
Reigada, Inés, Guarch-Pérez, Clara, Patel, Jayendra Z, Riool, Martijn, Savijoki, Kirsi, Yli-Kauhaluoma, Jari, Zaat, Sebastian A J, Fallarero, Adyary
Published in Microorganisms (Basel) (09.11.2020)
Published in Microorganisms (Basel) (09.11.2020)
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Journal Article
Strategies to Prevent Biofilm Infections on Biomaterials: Effect of Novel Naturally-Derived Biofilm Inhibitors on a Competitive Colonization Model of Titanium by Staphylococcus aureus and SaOS-2 Cells
Reigada, Inés, Pérez-Tanoira, Ramón, Patel, Jayendra Z, Savijoki, Kirsi, Yli-Kauhaluoma, Jari, Kinnari, Teemu J, Fallarero, Adyary
Published in Microorganisms (Basel) (29.02.2020)
Published in Microorganisms (Basel) (29.02.2020)
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Journal Article
Design and synthesis of etrasimod derivatives as potent antibacterial agents against Gram-positive bacteria
Zore, Matej, San-Martin-Galindo, Paola, Reigada, Ines, Hanski, Leena, Fallarero, Adyary, Yli-Kauhaluoma, Jari, Patel, Jayendra Z.
Published in European journal of medicinal chemistry (05.01.2024)
Published in European journal of medicinal chemistry (05.01.2024)
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Journal Article
Chloroquine fumardiamides as novel quorum sensing inhibitors
Beus, Maja, Savijoki, Kirsi, Patel, Jayendra Z., Yli-Kauhaluoma, Jari, Fallarero, Adyary, Zorc, Branka
Published in Bioorganic & medicinal chemistry letters (15.08.2020)
Published in Bioorganic & medicinal chemistry letters (15.08.2020)
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Journal Article
Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid α/β‑Hydrolase Domain 6 (ABHD6)
Mardon, Karine, Patel, Jayendra Z., Savinainen, Juha R., Stimson, Damion H. R., Oyagawa, Caitlin R. M., Grimsey, Natasha L., Migotto, Mary-anne, Njiru, Grace F. M., Hamilton, Brett R., Cowin, Gary, Yli-Kauhaluoma, Jari, Vanduffel, Wim, Blakey, Idriss, Bhalla, Rajiv, Cawthorne, Christopher, Celen, Sofie, Bormans, Guy, Thurecht, Kristofer J, Ahamed, Muneer
Published in Journal of medicinal chemistry (12.01.2023)
Published in Journal of medicinal chemistry (12.01.2023)
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Journal Article
Chiral 1,3,4-Oxadiazol-2-ones as Highly Selective FAAH Inhibitors
Patel, Jayendra Z, Parkkari, Teija, Laitinen, Tuomo, Kaczor, Agnieszka A, Saario, Susanna M, Savinainen, Juha R, Navia-Paldanius, Dina, Cipriano, Mariateresa, Leppänen, Jukka, Koshevoy, Igor O, Poso, Antti, Fowler, Christopher J, Laitinen, Jarmo T, Nevalainen, Tapio
Published in Journal of medicinal chemistry (14.11.2013)
Published in Journal of medicinal chemistry (14.11.2013)
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Journal Article
Comparative molecular field analysis and molecular dynamics studies of α/β hydrolase domain containing 6 (ABHD6) inhibitors
Kaczor, Agnieszka A., Targowska-Duda, Katarzyna M., Patel, Jayendra Z., Laitinen, Tuomo, Parkkari, Teija, Adams, Yahaya, Nevalainen, Tapio J., Poso, Antti
Published in Journal of molecular modeling (01.10.2015)
Published in Journal of molecular modeling (01.10.2015)
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Journal Article
Loratadine analogues as MAGL inhibitors
Patel, Jayendra Z., Ahenkorah, Stephen, Vaara, Miia, Staszewski, Marek, Adams, Yahaya, Laitinen, Tuomo, Navia-Paldanius, Dina, Parkkari, Teija, Savinainen, Juha R., Walczyński, Krzysztof, Laitinen, Jarmo T., Nevalainen, Tapio J.
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
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Journal Article
Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors
Patel, Jayendra Z., van Bruchem, John, Laitinen, Tuomo, Kaczor, Agnieszka A., Navia-Paldanius, Dina, Parkkari, Teija, Savinainen, Juha R., Laitinen, Jarmo T., Nevalainen, Tapio J.
Published in Bioorganic & medicinal chemistry (01.10.2015)
Published in Bioorganic & medicinal chemistry (01.10.2015)
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Journal Article
Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human α/β-hydrolase domain containing 11 (ABHD11)
Navia-Paldanius, Dina, Patel, Jayendra Z., López Navarro, Miriam, Jakupović, Hermina, Goffart, Steffi, Pasonen-Seppänen, Sanna, Nevalainen, Tapio J., Jääskeläinen, Tiina, Laitinen, Tuomo, Laitinen, Jarmo T., Savinainen, Juha R.
Published in European journal of pharmaceutical sciences (10.10.2016)
Published in European journal of pharmaceutical sciences (10.10.2016)
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Journal Article
Optimization of 1,2,5-Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors
Patel, Jayendra Z., Nevalainen, Tapio J., Savinainen, Juha R., Adams, Yahaya, Laitinen, Tuomo, Runyon, Robert S., Vaara, Miia, Ahenkorah, Stephen, Kaczor, Agnieszka A., Navia-Paldanius, Dina, Gynther, Mikko, Aaltonen, Niina, Joharapurkar, Amit A., Jain, Mukul R., Haka, Abigail S., Maxfield, Frederick R., Laitinen, Jarmo T., Parkkari, Teija
Published in ChemMedChem (01.02.2015)
Published in ChemMedChem (01.02.2015)
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Journal Article
Diaryl Dihydropyrazole-3-carboxamides with Significant In Vivo Antiobesity Activity Related to CB1 Receptor Antagonism: Synthesis, Biological Evaluation, and Molecular Modeling in the Homology Model
Joharapurkar, Amit, Raval, Saurin, Patel, Jayendra Z, Soni, Rina, Raval, Preeti, Gite, Archana, Goswami, Amitgiri, Sadhwani, Nisha, Gandhi, Neha, Patel, Harilal, Mishra, Bhupendra, Solanki, Manish, Pandey, Bipin, Jain, Mukul R, Patel, Pankaj R
Published in Journal of medicinal chemistry (29.11.2007)
Published in Journal of medicinal chemistry (29.11.2007)
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Journal Article
1,3,4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity determinants by molecular modelling
Käsnänen, Heikki, Minkkilä, Anna, Taupila, Susanna, Patel, Jayendra Z., Parkkari, Teija, Lahtela-Kakkonen, Maija, Saario, Susanna M., Nevalainen, Tapio, Poso, Antti
Published in European journal of pharmaceutical sciences (14.06.2013)
Published in European journal of pharmaceutical sciences (14.06.2013)
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Journal Article
Hair growth stimulator property of thienyl substituted pyrazole carboxamide derivatives as a cb1 receptor antagonist with in vivo antiobesity effect
Srivastava, Brijesh Kumar, Soni, Rina, Patel, Jayendra Z., Joharapurkar, Amit, Sadhwani, Nisha, Kshirsagar, Samadhan, Mishra, Bhupendra, Takale, Vijay, Gupta, Sunil, Pandya, Purvi, Kapadnis, Prashant, Solanki, Manish, Patel, Harilal, Mitra, Prasenjit, Jain, Mukul R., Patel, Pankaj R.
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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