ZYBT1, a potent, irreversible Bruton’s Tyrosine Kinase (BTK) inhibitor that inhibits the C481S BTK with profound efficacy against arthritis and cancer
Ghoshdastidar, Krishnarup, Patel, Hoshang, Bhayani, Hitesh, Patel, Ankit, Thakkar, Kinjal, Patel, Dinesh, Sharma, Manoranjan, Singh, Jaideep, Mohapatra, Jogeswar, Chatterjee, Abhijit, Patel, Dipam, Bahekar, Rajesh, Sharma, Rajiv, Gupta, Lakshmikant, Patel, Nirmal, Giri, Poonam, Srinivas, Nuggehally R., Jain, Mukul, Bandyopadhyay, Debdutta, Patel, Pankaj R., Desai, Ranjit C.
Published in Pharmacology research & perspectives (01.08.2020)
Published in Pharmacology research & perspectives (01.08.2020)
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Journal Article
Optimisation of momelotinib with improved potency and efficacy as pan-JAK inhibitor
Desai, Jigar, Patel, Bhaumin, Gite, Archana, Panchal, Nandini, Gite, Sanjay, Argade, Anil, Kumar, Jeevan, Sachchidanand, S., Bandyopadhyay, Debdutta, Ghoshdastidar, Krishnarup, Patel, Hoshang, Chatterjee, Abhijit, Mahapatra, Jogeshwar, Sharma, Manoranjan, Giri, Poonam, Kumar, Sanjay, Jain, Mukul, Sharma, Rajiv, Desai, Ranjit
Published in Bioorganic & medicinal chemistry letters (15.06.2022)
Published in Bioorganic & medicinal chemistry letters (15.06.2022)
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Journal Article
Discovery of a potent G-protein-coupled receptor 119 agonist for the treatment of type 2 diabetes
Pola, Suresh, Shah, Shailesh R., Pingali, Harikishore, Zaware, Pandurang, Thube, Baban, Makadia, Pankaj, Patel, Hoshang, Bandyopadhyay, Debdutta, Rath, Akshyaya, Giri, Suresh, Patel, Jitendra H., Ranvir, R.K., Sundar, S.R., Patel, Harilal, Kumar, Jeevan, Jain, Mukul R.
Published in Bioorganic & medicinal chemistry (01.04.2021)
Published in Bioorganic & medicinal chemistry (01.04.2021)
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Journal Article
Design, synthesis and biological evaluation of novel pyrazolo-pyrimidin-amines as potent and selective BTK inhibitors
Joshi, Darshan, Bahekar, Rajesh, Soman, Shubhangi, Jadav, Pradip, Patel, Dipam, Goswami, Amitgiri, Pethani, Jignesh, Kumar, Jeevan, Patel, Jitendra, Sundar, Rajesh, Goswami, Poonamgiri, Goshdastidar, Krishnarup, Patel, Hoshang, Patel, Ankit, Bandyopadhyay, Debdutta, Chattarjee, Abhijit, Sharma, Manoranjan, Jain, Mukul, Desai, Ranjit
Published in Bioorganic chemistry (01.01.2023)
Published in Bioorganic chemistry (01.01.2023)
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Journal Article
Discovery of diaminopyrimidine-carboxamide derivatives as JAK3 inhibitors
Bahekar, Rajesh, Panchal, Nandini, Soman, Shubhangi, Desai, Jigar, Patel, Dipam, Argade, Anil, Gite, Archana, Gite, Sanjay, Patel, Bhaumin, Kumar, Jeevan, S, Sachchidanand, Patel, Harilal, Sundar, Rajesh, Chatterjee, Abhijit, Mahapatra, Jogeswar, Patel, Hoshang, Ghoshdastidar, Krishnarup, Bandyopadhyay, Debdutta, Desai, Ranjit C.
Published in Bioorganic chemistry (01.06.2020)
Published in Bioorganic chemistry (01.06.2020)
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Journal Article