Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions
Fahed, Akl C, Wang, Minxian, Homburger, Julian R, Patel, Aniruddh P, Bick, Alexander G, Neben, Cynthia L, Lai, Carmen, Brockman, Deanna, Philippakis, Anthony, Ellinor, Patrick T, Cassa, Christopher A, Lebo, Matthew, Ng, Kenney, Lander, Eric S, Zhou, Alicia Y, Kathiresan, Sekar, Khera, Amit V
Published in Nature communications (20.08.2020)
Published in Nature communications (20.08.2020)
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Journal Article
Race, socioeconomic deprivation, and hospitalization for COVID-19 in English participants of a national biobank
Patel, Aniruddh P, Paranjpe, Manish D, Kathiresan, Nina P, Rivas, Manuel A, Khera, Amit V
Published in International journal for equity in health (06.07.2020)
Published in International journal for equity in health (06.07.2020)
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Journal Article
Association of premature menopause with incident pulmonary hypertension: A cohort study
Honigberg, Michael C, Patel, Aniruddh P, Lahm, Tim, Wood, Malissa J, Ho, Jennifer E, Kohli, Puja, Natarajan, Pradeep
Published in PloS one (10.03.2021)
Published in PloS one (10.03.2021)
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Journal Article
Prediction performance and fairness heterogeneity in cardiovascular risk models
Kartoun, Uri, Khurshid, Shaan, Kwon, Bum Chul, Patel, Aniruddh P, Batra, Puneet, Philippakis, Anthony, Khera, Amit V, Ellinor, Patrick T, Lubitz, Steven A, Ng, Kenney
Published in Scientific reports (22.07.2022)
Published in Scientific reports (22.07.2022)
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Journal Article
Lipoprotein(a) and Coronary Artery Disease Risk Without a Family History of Heart Disease
Finneran, Phoebe, Pampana, Akhil, Khetarpal, Sumeet A, Trinder, Mark, Patel, Aniruddh P, Paruchuri, Kaavya, Aragam, Krishna, Peloso, Gina M, Natarajan, Pradeep
Published in Journal of the American Heart Association (02.03.2021)
Published in Journal of the American Heart Association (02.03.2021)
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Journal Article
Polygenic Scores and Preclinical Cardiovascular Disease in Individuals With HIV: Insights From the REPRIEVE Trial
Zou, Roger S, Ruan, Yunfeng, Truong, Buu, Bhattacharya, Romit, Lu, Michael T, Karády, Júlia, Bernardo, Rachel, Finneran, Phoebe, Hornsby, Whitney, Fitch, Kathleen V, Ribaudo, Heather J, Zanni, Markella V, Douglas, Pamela S, Grinspoon, Steven K, Patel, Aniruddh P, Natarajan, Pradeep
Published in Journal of the American Heart Association (02.04.2024)
Published in Journal of the American Heart Association (02.04.2024)
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Journal Article
Quantifying and Understanding the Higher Risk of Atherosclerotic Cardiovascular Disease Among South Asian Individuals: Results From the UK Biobank Prospective Cohort Study
Patel, Aniruddh P, Wang, Minxian, Kartoun, Uri, Ng, Kenney, Khera, Amit V
Published in Circulation (New York, N.Y.) (10.08.2021)
Published in Circulation (New York, N.Y.) (10.08.2021)
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Journal Article
Lp(a) (Lipoprotein[a]) Concentrations and Incident Atherosclerotic Cardiovascular Disease: New Insights From a Large National Biobank
Patel, Aniruddh P, Wang, Minxian, Pirruccello, James P, Ellinor, Patrick T, Ng, Kenney, Kathiresan, Sekar, Khera, Amit V
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2021)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2021)
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Journal Article
Targeted exonic sequencing of GWAS loci in the high extremes of the plasma lipids distribution
Patel, Aniruddh P, Peloso, Gina M, Pirruccello, James P, Johansen, Christopher T, Dubé, Joseph B, Larach, Daniel B, Ban, Matthew R, Dallinge-Thie, Geesje M, Gupta, Namrata, Boehnke, Michael, Abecasis, Gonçalo R, Kastelein, John J.P, Hovingh, G. Kees, Hegele, Robert A, Rader, Daniel J, Kathiresan, Sekar
Published in Atherosclerosis (01.07.2016)
Published in Atherosclerosis (01.07.2016)
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Journal Article
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease
Patel, Aniruddh P, Wang, Minxian, Ruan, Yunfeng, Koyama, Satoshi, Clarke, Shoa L, Yang, Xiong, Tcheandjieu, Catherine, Agrawal, Saaket, Fahed, Akl C, Ellinor, Patrick T, Tsao, Philip S, Sun, Yan V, Cho, Kelly, Wilson, Peter W F, Assimes, Themistocles L, van Heel, David A, Butterworth, Adam S, Aragam, Krishna G, Natarajan, Pradeep, Khera, Amit V
Published in Nature medicine (01.07.2023)
Published in Nature medicine (01.07.2023)
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Journal Article
Genetic, sociodemographic, lifestyle, and clinical risk factors of recurrent coronary artery disease events: a population-based cohort study
Cho, So Mi Jemma, Koyama, Satoshi, Honigberg, Michael C, Surakka, Ida, Haidermota, Sara, Ganesh, Shriienidhie, Patel, Aniruddh P, Bhattacharya, Romit, Lee, Hokyou, Kim, Hyeon Chang, Natarajan, Pradeep
Published in European heart journal (21.09.2023)
Published in European heart journal (21.09.2023)
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Journal Article
Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians
Wang, Minxian, Menon, Ramesh, Mishra, Sanghamitra, Patel, Aniruddh P, Chaffin, Mark, Tanneeru, Deepak, Deshmukh, Manjari, Mathew, Oshin, Apte, Sanika, Devanboo, Christina S, Sundaram, Sumathi, Lakshmipathy, Praveena, Murugan, Sakthivel, Sharma, Krishna Kumar, Rajendran, Karthikeyan, Santhosh, Sam, Thachathodiyl, Rajesh, Ahamed, Hisham, Balegadde, Aniketh Vijay, Alexander, Thomas, Swaminathan, Krishnan, Gupta, Rajeev, Mullasari, Ajit S, Sigamani, Alben, Kanchi, Muralidhar, Peterson, Andrew S, Butterworth, Adam S, Danesh, John, Di Angelantonio, Emanuele, Naheed, Aliya, Inouye, Michael, Chowdhury, Rajiv, Vedam, Ramprasad L, Kathiresan, Sekar, Gupta, Ravi, Khera, Amit V
Published in Journal of the American College of Cardiology (11.08.2020)
Published in Journal of the American College of Cardiology (11.08.2020)
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Journal Article
Polygenic prediction of preeclampsia and gestational hypertension
Honigberg, Michael C, Truong, Buu, Khan, Raiyan R, Xiao, Brenda, Bhatta, Laxmi, Vy, Ha My T, Guerrero, Rafael F, Schuermans, Art, Selvaraj, Margaret Sunitha, Patel, Aniruddh P, Koyama, Satoshi, Cho, So Mi Jemma, Vellarikkal, Shamsudheen Karuthedath, Trinder, Mark, Urbut, Sarah M, Gray, Kathryn J, Brumpton, Ben M, Patil, Snehal, Zöllner, Sebastian, Antopia, Mariah C, Saxena, Richa, Nadkarni, Girish N, Do, Ron, Yan, Qi, Pe'er, Itsik, Verma, Shefali Setia, Gupta, Rajat M, Haas, David M, Martin, Hilary C, van Heel, David A, Laisk, Triin, Natarajan, Pradeep
Published in Nature medicine (01.06.2023)
Published in Nature medicine (01.06.2023)
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Journal Article