Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial
McInnes, Iain B, Prof, Mease, Philip J, Prof, Kirkham, Bruce, MD, Kavanaugh, Arthur, Prof, Ritchlin, Christopher T, Prof, Rahman, Proton, Prof, van der Heijde, Désirée, Prof, Landewé, Robert, Prof, Conaghan, Philip G, Prof, Gottlieb, Alice B, Prof, Richards, Hanno, MD, Pricop, Luminita, MD, Ligozio, Gregory, MSc, Patekar, Manmath, MD, Mpofu, Shephard, MD
Published in The Lancet (British edition) (19.09.2015)
Published in The Lancet (British edition) (19.09.2015)
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Secukinumab demonstrates high efficacy and a favorable safety profile over 52 weeks in Chinese patients with moderate to severe plaque psoriasis
Cai, Lin, Zhang, Jian-Zhong, Yao, Xu, Gu, Jun, Liu, Quan-Zhong, Zheng, Min, Zhang, Shi-Fa, Xu, Jin-Hua, Li, Cheng-Xin, Cheng, Hao, Guo, Qing, Pan, Wei-Li, Li, Shen-Qiu, Li, Ruo-Yu, Guo, Zai-Pei, Song, Zhi-Qi, Li, Shan-Shan, Dong, Xiu-Qin, Wang, Linda, Fu, Rong, Regnault, Pascaline, Charef, Pascal, Mazur, Rafal, Patekar, Manmath
Published in Chinese medical journal (20.11.2020)
Published in Chinese medical journal (20.11.2020)
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Secukinumab in Pediatric Patients with Plaque Psoriasis: Pooled Safety Analysis from Two Phase 3 Randomized Clinical Trials
Sticherling, Michael, Nikkels, Arjen F., Hamza, Ashraf M., Kwong, Pearl, Szepietowski, Jacek C., El Sayed, Mahira, Ghislain, Pierre-Dominique, Khotko, Alkes A., Patekar, Manmath, Ortmann, Christine-Elke, Forrer, Pascal, Papanastasiou, Philemon, Keefe, Deborah
Published in American journal of clinical dermatology (01.09.2023)
Published in American journal of clinical dermatology (01.09.2023)
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Secukinumab is Superior to Ustekinumab in Clearing Skin in Patients with Moderate to Severe Plaque Psoriasis (16-Week CLARITY Results)
Bagel, Jerry, Nia, John, Hashim, Peter W., Patekar, Manmath, de Vera, Ana, Hugot, Sophie, Sheng, Kuan, Xia, Summer, Gilloteau, Isabelle, Muscianisi, Elisa, Blauvelt, Andrew, Lebwohl, Mark
Published in Dermatology and therapy (01.12.2018)
Published in Dermatology and therapy (01.12.2018)
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Comprehensive Assessment of Pharmacokinetics, Pharmacodynamics, and Tolerability of Ligelizumab in Healthy Volunteers and Patients with Chronic Spontaneous Urticaria to Optimize Its Subcutaneous Delivery System
Ji, Yan, Calonder, Claudio, Kirsilä, Tiina, Burciu, Alis, Tisu, Matjaz, Joubert, Yolandi, Laurent, Nathalie, Hua, Eva, Patekar, Manmath, Drollmann, Anton, Woessner, Ralph
Published in Pharmaceutics (01.09.2023)
Published in Pharmaceutics (01.09.2023)
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Secukinumab dosing every 2 weeks demonstrated superior efficacy compared with dosing every 4 weeks in patients with psoriasis weighing 90 kg or more: results of a randomized controlled trial
Augustin, Matthias, Reich, Kristian, Yamauchi, Paul, Pinter, Andreas, Bagel, Jerry, Dahale, Swapnil, You, Ruquan, Bruin, Gerard, Djimopoulos, Jimena, Paguet, Bertrand, Charef, Pascal, Patekar, Manmath, Keefe, Deborah
Published in British journal of dermatology (1951) (01.06.2022)
Published in British journal of dermatology (1951) (01.06.2022)
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25754 Presence of psoriatic arthritis has no impact on the clinical efficacy and safety of secukinumab in patients with psoriasis: Pooled analysis of the phase 3 CLEAR and CLARITY trials
Bagel, Jerry, Blauvelt, Andrew, Tyring, Stephen, Patekar, Manmath, Meng, Xiangyi, Lebwohl, Mark
Published in Journal of the American Academy of Dermatology (01.09.2021)
Published in Journal of the American Academy of Dermatology (01.09.2021)
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A phase 3 open-label, randomized multicenter study to evaluate efficacy and safety of secukinumab in pediatric patients with moderate to severe plaque psoriasis: 24-week results
Magnolo, Nina, Kingo, Külli, Laquer, Vivian, Browning, John, Reich, Adam, Szepietowski, Jacek C., Keefe, Deborah, Mazur, Rafal, Ghelani, Prayashi, Forrer, Pascal, Wraith, LindaAnn, Patekar, Manmath
Published in Journal of the American Academy of Dermatology (01.01.2022)
Published in Journal of the American Academy of Dermatology (01.01.2022)
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14190 Treatment with secukinumab of severe plaque psoriasis in pediatric patients: Study design and baseline characteristics of a double-blind study
Kaszuba, Andrzej, Papanastasiou, Philemon, Keefe, Deborah, Patekar, Manmath, Zhang, Lixin, Wraith, Linda Ann, Tsianakas, Dr. A
Published in Journal of the American Academy of Dermatology (01.12.2020)
Published in Journal of the American Academy of Dermatology (01.12.2020)
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Association of Secukinumab Treatment With Tuberculosis Reactivation in Patients With Psoriasis, Psoriatic Arthritis, or Ankylosing Spondylitis
Elewski, Boni E, Baddley, John W, Deodhar, Atul A, Magrey, Marina, Rich, Phoebe A, Soriano, Enrique R, Soung, Jennifer, Bao, Weibin, Keininger, Dorothy, Marfo, Kwaku, Patekar, Manmath, Sharma, Abhishek, Shete, Abhijit, Lebwohl, Mark Gabriel
Published in JAMA dermatology (Chicago, Ill.) (01.01.2021)
Published in JAMA dermatology (Chicago, Ill.) (01.01.2021)
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Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria: Results from the Phase-3 Pivotal Trials
Ensina, Luis Felipe, Bernstein, Jonathan, Sussman, Gordon, Maurer, Marcus, Giménez-Arnau, Ana Maria, Saini, Sarabjit, Varanasi, Vineeth, Barve, Avantika, Hua, Eva, Patekar, Manmath, Severin, Thomas
Published in Journal of allergy and clinical immunology (01.02.2023)
Published in Journal of allergy and clinical immunology (01.02.2023)
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25482 Secukinumab efficacy and safety profile in pediatric patients with severe chronic plaque psoriasis up to 1 year
Bodemer, Christine, Kaszuba, Andrzej, Kingo, Külli, Tsianakas, Athanasios, Morita, Akimichi, Rivas, Enrique, Papanastasiou, Philemon, Patekar, Manmath, Papavassilis, Charis, Bruin, Gerard, You, Ruquan
Published in Journal of the American Academy of Dermatology (01.09.2021)
Published in Journal of the American Academy of Dermatology (01.09.2021)
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27599 Secukinumab administration by a 2 mL autoinjector demonstrates high efficacy with comparable safety and tolerability in adult patients with plaque psoriasis: 16-week results from MATURE
Sigurgeirsson, Bardur, Browning, John, Tyring, Stephen, Szepietowski, Jacek C., Rivera-Díaz, Raquel, Effendy, Isaak, Bruin, Gerard, Paguet, Bertrand, Fu, Rong, Hampele, Isabelle, Patekar, Manmath
Published in Journal of the American Academy of Dermatology (01.09.2021)
Published in Journal of the American Academy of Dermatology (01.09.2021)
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26860 Secukinumab treatment demonstrated high efficacy and safety in pediatric patients with moderate-to-severe plaque psoriasis: 52-week results from a randomized trial
Magnolo, Nina, Kingo, Külli, Laquer, Vivian, Browning, John, Reich, Adam, Szepietowski, Jacek C., Keefe, Deborah, Mazur, Rafal, Ghelani, Prayashi, Forrer, Pascal, Patekar, Manmath
Published in Journal of the American Academy of Dermatology (01.09.2021)
Published in Journal of the American Academy of Dermatology (01.09.2021)
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27519 Efficacy, pharmacokinetics, and tolerability of subcutaneous secukinumab injections with 2 mL prefilled syringes (300 mg) in adult subjects with moderate to severe plaque psoriasis
Sigurgeirsson, Bardur, Schäkel, Knut, Hong, Chih-Ho, Effendy, Isaak, Placek, Waldemar, Rich, Phoebe, Bruin, Gerard, Charef, Pascal, Fu, Rong, Hampele, Isabelle, Patekar, Manmath
Published in Journal of the American Academy of Dermatology (01.09.2021)
Published in Journal of the American Academy of Dermatology (01.09.2021)
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15261 Lack of tuberculosis reactivation in 12,319 patients with psoriasis, psoriatic arthritis, or ankylosing spondylitis treated with secukinumab: An ad hoc analysis of pooled safety data from 28 clinical trials
Elewski, Boni, Baddley, John W., Deodhar, Atul, Magrey, Marina, Rich, Phoebe, Soriano, Enrique, Soung, Jennifer, Bao, Weibin, Patekar, Manmath, Lebwohl, Mark, Sharma, Abhishek
Published in Journal of the American Academy of Dermatology (01.12.2020)
Published in Journal of the American Academy of Dermatology (01.12.2020)
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Comparison of pharmacokinetics, safety and tolerability of secukinumab administered subcutaneously using different delivery systems in healthy volunteers and in psoriasis patients
Bruin, Gerard, Hockey, Hans‐Ulrich P., La Stella, Phillip, Sigurgeirsson, Bárdur, Fu, Rong, Patekar, Manmath, Charef, Pascal, Woessner, Ralph, Boutouyrie‐Dumont, Bruno
Published in British journal of clinical pharmacology (01.02.2020)
Published in British journal of clinical pharmacology (01.02.2020)
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Efficacy of Secukinumab Across Subgroups and Overall Safety in Pediatric Patients with Moderate to Severe Plaque Psoriasis: Week 52 Results from a Phase III Randomized Study
Magnolo, Nina, Kingo, Külli, Laquer, Vivian, Browning, John, Reich, Adam, Szepietowski, Jacek C., Keefe, Deborah, Papanastasiou, Philemon, Bao, Weibin, Forrer, Pascal, Patekar, Manmath
Published in Paediatric drugs (01.07.2022)
Published in Paediatric drugs (01.07.2022)
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Journal Article
Secukinumab demonstrates efficacy, safety, and tolerability upon administration by 2 ml autoinjector in adult patients with plaque psoriasis: 52‐week results from MATURE, a randomized, placebo‐controlled trial
Sigurgeirsson, Bardur, Browning, John, Tyring, Stephen, Szepietowski, Jacek C., Rivera‐Díaz, Raquel, Effendy, Isaak, Keefe, Deborah, Bruin, Gerard, Paguet, Bertrand, Fu, Rong, Hampele, Isabelle, Reinhardt, Maximilian, Patekar, Manmath
Published in Dermatologic therapy (01.03.2022)
Published in Dermatologic therapy (01.03.2022)
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