TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
Pastor, William A., Aravind, L., Rao, Anjana
Published in Nature reviews. Molecular cell biology (01.06.2013)
Published in Nature reviews. Molecular cell biology (01.06.2013)
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Journal Article
Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory
Pastor, William A., Chen, Di, Liu, Wanlu, Kim, Rachel, Sahakyan, Anna, Lukianchikov, Anastasia, Plath, Kathrin, Jacobsen, Steven E., Clark, Amander T.
Published in Cell stem cell (03.03.2016)
Published in Cell stem cell (03.03.2016)
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Journal Article
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway
Freed-Pastor, William A., Mizuno, Hideaki, Zhao, Xi, Langerød, Anita, Moon, Sung-Hwan, Rodriguez-Barrueco, Ruth, Barsotti, Anthony, Chicas, Agustin, Li, Wencheng, Polotskaia, Alla, Bissell, Mina J., Osborne, Timothy F., Tian, Bin, Lowe, Scott W., Silva, Jose M., Børresen-Dale, Anne-Lise, Levine, Arnold J., Bargonetti, Jill, Prives, Carol
Published in Cell (20.01.2012)
Published in Cell (20.01.2012)
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Journal Article
TET proteins and 5-methylcytosine oxidation in hematological cancers
Ko, Myunggon, An, Jungeun, Pastor, William A., Koralov, Sergei B., Rajewsky, Klaus, Rao, Anjana
Published in Immunological reviews (01.01.2015)
Published in Immunological reviews (01.01.2015)
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Journal Article
The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing
Huang, Yun, Pastor, William A, Shen, Yinghua, Tahiliani, Mamta, Liu, David R, Rao, Anjana
Published in PloS one (26.01.2010)
Published in PloS one (26.01.2010)
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Journal Article
Control of Foxp3 stability through modulation of TET activity
Yue, Xiaojing, Trifari, Sara, Äijö, Tarmo, Tsagaratou, Ageliki, Pastor, William A, Zepeda-Martínez, Jorge A, Lio, Chan-Wang J, Li, Xiang, Huang, Yun, Vijayanand, Pandurangan, Lähdesmäki, Harri, Rao, Anjana
Published in The Journal of experimental medicine (07.03.2016)
Published in The Journal of experimental medicine (07.03.2016)
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Journal Article
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
Tahiliani, Mamta, Koh, Kian Peng, Shen, Yinghua, Pastor, William A, Bandukwala, Hozefa, Brudno, Yevgeny, Agarwal, Suneet, Iyer, Lakshminarayan M, Liu, David R, Aravind, L, Rao, Anjana
Published in Science (American Association for the Advancement of Science) (15.05.2009)
Published in Science (American Association for the Advancement of Science) (15.05.2009)
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Journal Article
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
Ko, Myunggon, An, Jungeun, Bandukwala, Hozefa S., Chavez, Lukas, Äijö, Tarmo, Pastor, William A., Segal, Matthew F., Li, Huiming, Koh, Kian Peng, Lähdesmäki, Harri, Hogan, Patrick G., Aravind, L., Rao, Anjana
Published in Nature (London) (02.05.2013)
Published in Nature (London) (02.05.2013)
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Journal Article
TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells
Tsagaratou, Ageliki, González-Avalos, Edahí, Rautio, Sini, Scott-Browne, James P, Togher, Susan, Pastor, William A, Rothenberg, Ellen V, Chavez, Lukas, Lähdesmäki, Harri, Rao, Anjana
Published in Nature immunology (01.01.2017)
Published in Nature immunology (01.01.2017)
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Journal Article
SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer
Xue, Yibo, Meehan, Brian, Fu, Zheng, Wang, Xue Qing D., Fiset, Pierre Olivier, Rieker, Ralf, Levins, Cameron, Kong, Tim, Zhu, Xianbing, Morin, Geneviève, Skerritt, Lashanda, Herpel, Esther, Venneti, Sriram, Martinez, Daniel, Judkins, Alexander R., Jung, Sungmi, Camilleri-Broet, Sophie, Gonzalez, Anne V., Guiot, Marie-Christine, Lockwood, William W., Spicer, Jonathan D., Agaimy, Abbas, Pastor, William A., Dostie, Josée, Rak, Janusz, Foulkes, William D., Huang, Sidong
Published in Nature communications (04.02.2019)
Published in Nature communications (04.02.2019)
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Journal Article
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells
Huang, Yun, Chavez, Lukas, Chang, Xing, Wang, Xue, Pastor, William A., Kang, Jinsuk, Zepeda-Martínez, Jorge A., Pape, Utz J., Jacobsen, Steven E., Peters, Bjoern, Rao, Anjana
Published in Proceedings of the National Academy of Sciences - PNAS (28.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (28.01.2014)
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Journal Article
Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling
Li, Xiang, Yue, Xiaojing, Pastor, William A., Lin, Lizhu, Georges, Romain, Chavez, Lukas, Evans, Sylvia M., Rao, Anjana
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2016)
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Journal Article
ZIC2 and ZIC3 promote SWI/SNF recruitment to safeguard progression towards human primed pluripotency
Hossain, Ishtiaque, Priam, Pierre, Reynoso, Sofia C., Sahni, Sahil, Zhang, Xiao X., Côté, Laurence, Doumat, Joelle, Chik, Candus, Fu, Tianxin, Lessard, Julie A., Pastor, William A.
Published in Nature communications (02.10.2024)
Published in Nature communications (02.10.2024)
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Journal Article
The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation
Chen, Di, Liu, Wanlu, Zimmerman, Jill, Pastor, William A., Kim, Rachel, Hosohama, Linzi, Ho, Jamie, Aslanyan, Marianna, Gell, Joanna J., Jacobsen, Steven E., Clark, Amander T.
Published in Cell reports (Cambridge) (26.12.2018)
Published in Cell reports (Cambridge) (26.12.2018)
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Journal Article
Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis
Kang, Jinsuk, Lienhard, Matthias, Pastor, William A., Chawla, Ashu, Novotny, Mark, Tsagaratou, Ageliki, Lasken, Roger S., Thompson, Elizabeth C., Surani, M. Azim, Koralov, Sergei B., Kalantry, Sundeep, Chavez, Lukas, Rao, Anjana
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2015)
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Journal Article
MORC1 represses transposable elements in the mouse male germline
Pastor, William A., Stroud, Hume, Nee, Kevin, Liu, Wanlu, Pezic, Dubravka, Manakov, Sergei, Lee, Serena A., Moissiard, Guillaume, Zamudio, Natasha, Bourc’his, Déborah, Aravin, Alexei A., Clark, Amander T., Jacobsen, Steven E.
Published in Nature communications (12.12.2014)
Published in Nature communications (12.12.2014)
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Journal Article
Deletion of RBMX RGG/RG motif in Shashi-XLID syndrome leads to aberrant p53 activation and neuronal differentiation defects
Cai, Ting, Cinkornpumin, Jessica K., Yu, Zhenbao, Villarreal, Oscar D., Pastor, William A., Richard, Stéphane
Published in Cell reports (Cambridge) (13.07.2021)
Published in Cell reports (Cambridge) (13.07.2021)
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Journal Article
In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse
Morselli, Marco, Pastor, William A, Montanini, Barbara, Nee, Kevin, Ferrari, Roberto, Fu, Kai, Bonora, Giancarlo, Rubbi, Liudmilla, Clark, Amander T, Ottonello, Simone, Jacobsen, Steven E, Pellegrini, Matteo
Published in eLife (07.04.2015)
Published in eLife (07.04.2015)
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