Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression
Boussadia, B, Ghosh, C, Plaud, C, Pascussi, J.M, de Bock, F, Rousset, M.C, Janigro, D, Marchi, N
Published in Neuroscience (05.12.2014)
Published in Neuroscience (05.12.2014)
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Journal Article
The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors
Pascussi, J.M., Gerbal-Chaloin, S., Drocourt, L., Maurel, P., Vilarem, M.J.
Published in BBA - General Subjects (17.02.2003)
Published in BBA - General Subjects (17.02.2003)
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Book Review
Journal Article
Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites
Sérée, E, Villard, P-H, Pascussi, J-M, Pineau, T, Maurel, P, Nguyen, Q B, Fallone, F, Martin, P-M, Champion, S, Lacarelle, B, Savouret, J-F, Barra, Y
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2004)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2004)
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Journal Article
Induction of CYP2C Genes in Human Hepatocytes in Primary Culture
Gerbal-Chaloin, S, Pascussi, J M, Pichard-Garcia, L, Daujat, M, Waechter, F, Fabre, J M, Carrère, N, Maurel, P
Published in Drug metabolism and disposition (01.03.2001)
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Published in Drug metabolism and disposition (01.03.2001)
Journal Article
Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor
Pascussi, J M, Drocourt, L, Gerbal-Chaloin, S, Fabre, J M, Maurel, P, Vilarem, M J
Published in European journal of biochemistry (01.12.2001)
Published in European journal of biochemistry (01.12.2001)
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Journal Article
Tyrosine 319 in the Interdomain B of ZAP-70 Is a Binding Site for the Src Homology 2 Domain of Lck
Pelosi, Michele, Di Bartolo, Vincenzo, Mounier, Virginie, Mège, Dominique, Pascussi, Jean-Marc, Dufour, Evelyne, Blondel, Arnaud, Acuto, Oreste
Published in The Journal of biological chemistry (14.05.1999)
Published in The Journal of biological chemistry (14.05.1999)
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Journal Article
The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor
Calleja, C, Pascussi, J M, Mani, J C, Maurel, P, Vilarem, M J
Published in Nature medicine (01.01.1998)
Published in Nature medicine (01.01.1998)
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Journal Article
Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators
Pascussi, J M, Drocourt, L, Fabre, J M, Maurel, P, Vilarem, M J
Published in Molecular pharmacology (01.08.2000)
Published in Molecular pharmacology (01.08.2000)
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Journal Article
Interleukin-6 Negatively Regulates the Expression of Pregnane X Receptor and Constitutively Activated Receptor in Primary Human Hepatocytes
Pascussi, Jean-Marc, Gerbal-Chaloin, Sabine, Pichard-Garcia, Lydiane, Daujat, Martine, Fabre, Jean-Michel, Maurel, Patrick, Vilarem, Marie-José
Published in Biochemical and biophysical research communications (11.08.2000)
Published in Biochemical and biophysical research communications (11.08.2000)
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Journal Article
The Small Heterodimer Partner Interacts with the Pregnane X Receptor and Represses Its Transcriptional Activity
Ourlin, Jean Claude, Lasserre, Fredéric, Pineau, Thierry, Fabre, Jean Michel, Sa-Cunha, Antonio, Maurel, Patrick, Vilarem, Marie-José, Pascussi, Jean Marc
Published in Molecular endocrinology (Baltimore, Md.) (01.09.2003)
Published in Molecular endocrinology (Baltimore, Md.) (01.09.2003)
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Journal Article
Calcium Channel Modulators of the Dihydropyridine Family Are Human Pregnane X Receptor Activators and Inducers of CYP3A, CYP2B, and CYP2C in Human Hepatocytes
DROCOURT, Lionel, PASCUSSI, Jean-Marc, ASSENAT, Eric, FABRE, Jean-Michel, MAUREL, Patrick, VILAREM, Marie-Jose
Published in Drug metabolism and disposition (01.10.2001)
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Published in Drug metabolism and disposition (01.10.2001)
Journal Article
Evidence for the Presence of a Functional Pregnane X Receptor Response Element in the CYP3A7 Promoter Gene
Pascussi, Jean-Marc, Jounaidi, Youssef, Drocourt, Lionel, Domergue, Jacques, Balabaud, Charles, Maurel, Patrick, Vilarem, Marie-Josée
Published in Biochemical and biophysical research communications (05.07.1999)
Published in Biochemical and biophysical research communications (05.07.1999)
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Journal Article
Estrogens and antiestrogens activate hPXR
Mnif, Wissem, Pascussi, Jean-Marc, Pillon, Arnaud, Escande, Aurélie, Bartegi, Aghleb, Nicolas, Jean-Claude, Cavaillès, Vincent, Duchesne, Marie-Josèphe, Balaguer, Patrick
Published in Toxicology letters (05.04.2007)
Published in Toxicology letters (05.04.2007)
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Journal Article
Regulation of Xenobiotic Detoxification by Nuclear Receptors
Pascussi, JM, Gerbal-Chaloin, S, Drocourt, L, Pichard-Garcia, L, Vilarem, MJ, Maurel, P
Published in Medicinal chemistry research (01.01.2004)
Published in Medicinal chemistry research (01.01.2004)
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Journal Article
Transcriptional regulation of the human CYP46A1 brain-specific expression by Sp transcription factors
Milagre, Inês, Nunes, Maria João, Gama, Maria João, Silva, Rui Fernando, Pascussi, Jean Marc, Lechner, Maria C, Rodrigues, Elsa
Published in Journal of neurochemistry (01.07.2008)
Published in Journal of neurochemistry (01.07.2008)
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Journal Article
Effects of the mycotoxins aflatoxin B1, zearalenone and ochratoxine A on nuclear receptors PXR, CAR and AhR expression and corresponding CYP 450 in primary cultured human hepatocytes
Hassen, Wafa, Ayed-Boussema, Imen, Pascussi, Jean-Marc, Maurel, Patrick, Bacha, Hassen, Wafa, Hassen
Published in Toxicology letters (13.09.2009)
Published in Toxicology letters (13.09.2009)
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Journal Article
Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia
Pascussi, Jean Marc, Robert, Agnes, Nguyen, Minh, Walrant-Debray, Odile, Garabedian, Michèle, Martin, Pascal, Pineau, Thierry, Saric, Jean, Navarro, Fréderic, Maurel, Patrick, Vilarem, Marie Josè
Published in The Journal of clinical investigation (01.01.2005)
Published in The Journal of clinical investigation (01.01.2005)
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Journal Article
Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes
Drocourt, Lionel, Ourlin, Jean-Claude, Pascussi, Jean-Marc, Maurel, Patrick, Vilarem, Marie-José
Published in The Journal of biological chemistry (12.07.2002)
Published in The Journal of biological chemistry (12.07.2002)
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Journal Article