Structure-Activity Study of Tripeptide Thrombin Inhibitors Using .alpha.-Alkyl Amino Acids and Other Conformationally Constrained Amino Acid Substitutions
Shuman, Robert T, Rothenberger, Robert B, Campbell, Charles S, Smith, Gerald F, Gifford-Moore, Donetta S, Paschal, Jonathan W, Gesellchen, Paul D
Published in Journal of medicinal chemistry (01.10.1995)
Published in Journal of medicinal chemistry (01.10.1995)
Get full text
Journal Article
Synthesis of the Four Isomers of 4-Aminopyrrolidine-2,4-dicarboxylate: Identification of a Potent, Highly Selective, and Systemically-Active Agonist for Metabotropic Glutamate Receptors Negatively Coupled to Adenylate Cyclase
Monn, James A, Valli, Matthew J, Johnson, Bryan G, Salhoff, Craig R, Wright, Rebecca A, Howe, Trevor, Bond, Ann, Lodge, David, Spangle, Larry A, Paschal, Jonathan W, Campbell, Jack B, Griffey, Kelly, Tizzano, Joseph P, Schoepp, Darryle D
Published in Journal of medicinal chemistry (19.07.1996)
Published in Journal of medicinal chemistry (19.07.1996)
Get full text
Journal Article
An Efficient Synthesis of cis- and trans-Methyl-3-hydroxy-2-pyrrolidone- 5-carboxylates, Key Intermediates for the Synthesis of γ-Substituted Glutamic Acid Analogs
Heinz, Lawrence J, Lunn, W. H. W, Murff, R. E, Paschal, Jonathan W, Spangle, Larry A
Published in Journal of organic chemistry (12.07.1996)
Published in Journal of organic chemistry (12.07.1996)
Get full text
Journal Article
4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action
Ornstein, Paul L, Schoepp, Darryle D, Arnold, M. Brian, Leander, J. David, Lodge, David, Paschal, Jonathan W, Elzey, Tom
Published in Journal of medicinal chemistry (01.01.1991)
Published in Journal of medicinal chemistry (01.01.1991)
Get full text
Journal Article
An improved synthesis of homoproline and derivatives
Shuman, Robert T, Ornstein, Paul L, Paschal, Jonathan W, Gesellchen, Paul D
Published in Journal of organic chemistry (1990)
Published in Journal of organic chemistry (1990)
Get full text
Journal Article
Syntheses of 6-oxodecahydroisoquinoline-3-carboxylates. Useful intermediates for the preparation of conformationally defined excitatory amino acid antagonists
Ornstein, Paul L, Arnold, M. Brian, Augenstein, Nancy K, Paschal, Jonathan W
Published in Journal of organic chemistry (01.07.1991)
Published in Journal of organic chemistry (01.07.1991)
Get full text
Journal Article
6-Substituted decahydroisoquinoline-3-carboxylic acids as potent and selective conformationally constrained NMDA receptor antagonists
Ornstein, Paul L, Schoepp, Darryle D, Arnold, M. Brian, Augenstein, Nancy K, Lodge, David, Millar, John D, Chambers, John, Campbell, Jack, Paschal, Jonathan W
Published in Journal of medicinal chemistry (01.09.1992)
Published in Journal of medicinal chemistry (01.09.1992)
Get full text
Journal Article
Tripeptide LY301621 and Its Diastereomers as Methicillin Potentiators against Methicillin Resistant Staphylococcus aureus
BID, CLARK N., HALLIGAN, NOREEN G., NICAS, THALIA I., MULLEN, DEBORAH L., BUTLER, THOMAS F., LONCHARICH, RICHARD J., PASCHAL, JONATHAN W., SCHOFIELD, CHRISTOPHER J., WESTWOOD, NICHOLAS J., CHENG, LEIFENG
Published in Journal of antibiotics (01.03.1997)
Published in Journal of antibiotics (01.03.1997)
Get full text
Journal Article
Synthesis and pharmacology of a series of 3- and 4-(phosphonoalkyl)pyridine- and -piperidine-2-carboxylic acids. Potent N-methyl-D-aspartate receptor antagonists
Ornstein, Paul L, Schaus, John M, Chambers, John W, Huser, Diane L, Leander, J. David, Wong, David T, Paschal, Jonathan W, Jones, Noel D, Deeter, Jack B
Published in Journal of medicinal chemistry (01.04.1989)
Published in Journal of medicinal chemistry (01.04.1989)
Get full text
Journal Article
An enantioselective synthesis of D-(-)- and L-(+)-2-amino-3-phosphonopropanoic acid
Smith, Edward C. R, McQuaid, Loretta A, Paschal, Jonathan W, DeHoniesto, Juel
Published in Journal of organic chemistry (01.07.1990)
Published in Journal of organic chemistry (01.07.1990)
Get full text
Journal Article
Synthesis of ring-contracted derivatives of erythromycin
Kirst, Herbert A, Wind, Julie A, Paschal, Jonathan W
Published in Journal of organic chemistry (01.09.1987)
Published in Journal of organic chemistry (01.09.1987)
Get full text
Journal Article
The structures of A10255 B, -G and -J: new thiopeptide antibiotics produced by Streptomyces gardneri
Debono, Manuel, Molloy, R. Michael, Occolowitz, John L, Paschal, Jonathan W, Hunt, Ann H, Michel, Karl H, Martin, James W
Published in Journal of organic chemistry (01.09.1992)
Published in Journal of organic chemistry (01.09.1992)
Get full text
Journal Article
The structures of A10255 B, -G, and -J: new thiopeptide antibiotics produced by Streptomyces gardneri. [Erratum to document cited in CA117(15):146817c]
Debono, Manuel, Molloy, R. Michael, Occolowitz, John L, Paschal, Jonathan W, Hunt, Ann W, Michel, Karl H, Martin, James W
Published in Journal of organic chemistry (01.03.1993)
Published in Journal of organic chemistry (01.03.1993)
Get full text
Journal Article
Bicyclic and tricyclic ergoline partial structures. Rigid 3-(2-aminoethyl)pyrroles and 3- and 4-(2-aminoethyl)pyrazoles as dopamine agonists
Bach, Nicholas J, Kornfeld, Edmund C, Jones, Noel D, Chaney, Michael O, Dorman, Douglas E, Paschal, Jonathan W, Clemens, James A, Smalstig, E. Barry
Published in Journal of medicinal chemistry (01.05.1980)
Published in Journal of medicinal chemistry (01.05.1980)
Get full text
Journal Article