Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals
Stanzick, Kira J., Li, Yong, Schlosser, Pascal, Gorski, Mathias, Wuttke, Matthias, Thomas, Laurent F., Rasheed, Humaira, Rowan, Bryce X., Graham, Sarah E., Vanderweff, Brett R., Patil, Snehal B., Robinson-Cohen, Cassiane, Gaziano, John M., O’Donnell, Christopher J., Willer, Cristen J., Hallan, Stein, Åsvold, Bjørn Olav, Gessner, Andre, Hung, Adriana M., Pattaro, Cristian, Köttgen, Anna, Stark, Klaus J., Heid, Iris M., Winkler, Thomas W.
Published in Nature communications (16.07.2021)
Published in Nature communications (16.07.2021)
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Journal Article
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans
Schlosser, Pascal, Li, Yong, Sekula, Peggy, Raffler, Johannes, Grundner-Culemann, Franziska, Pietzner, Maik, Cheng, Yurong, Wuttke, Matthias, Steinbrenner, Inga, Schultheiss, Ulla T., Kotsis, Fruzsina, Kacprowski, Tim, Forer, Lukas, Hausknecht, Birgit, Ekici, Arif B., Nauck, Matthias, Völker, Uwe, Walz, Gerd, Oefner, Peter J., Kronenberg, Florian, Mohney, Robert P., Köttgen, Michael, Suhre, Karsten, Eckardt, Kai-Uwe, Kastenmüller, Gabi, Köttgen, Anna
Published in Nature genetics (01.02.2020)
Published in Nature genetics (01.02.2020)
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Journal Article
Epigenome-wide association studies identify DNA methylation associated with kidney function
Chu, Audrey Y., Tin, Adrienne, Schlosser, Pascal, Ko, Yi-An, Qiu, Chengxiang, Yao, Chen, Joehanes, Roby, Grams, Morgan E., Liang, Liming, Gluck, Caroline A., Liu, Chunyu, Coresh, Josef, Hwang, Shih-Jen, Levy, Daniel, Boerwinkle, Eric, Pankow, James S., Yang, Qiong, Fornage, Myriam, Fox, Caroline S., Susztak, Katalin, Köttgen, Anna
Published in Nature communications (03.11.2017)
Published in Nature communications (03.11.2017)
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Journal Article
SLC17A1/3 transporters mediate renal excretion of Lac-Phe in mice and humans
Li, Veronica L., Xiao, Shuke, Schlosser, Pascal, Scherer, Nora, Wiggenhorn, Amanda L., Spaas, Jan, Tung, Alan Sheng-Hwa, Karoly, Edward D., Köttgen, Anna, Long, Jonathan Z.
Published in Nature communications (12.08.2024)
Published in Nature communications (12.08.2024)
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Journal Article
Transcriptome- and proteome-wide association studies nominate determinants of kidney function and damage
Schlosser, Pascal, Zhang, Jingning, Liu, Hongbo, Surapaneni, Aditya L, Rhee, Eugene P, Arking, Dan E, Yu, Bing, Boerwinkle, Eric, Welling, Paul A, Chatterjee, Nilanjan, Susztak, Katalin, Coresh, Josef, Grams, Morgan E
Published in Genome Biology (26.06.2023)
Published in Genome Biology (26.06.2023)
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Journal Article
Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism
Cheng, Yurong, Schlosser, Pascal, Hertel, Johannes, Sekula, Peggy, Oefner, Peter J., Spiekerkoetter, Ute, Mielke, Johanna, Freitag, Daniel F., Schmidts, Miriam, Kronenberg, Florian, Eckardt, Kai-Uwe, Thiele, Ines, Li, Yong, Köttgen, Anna
Published in Nature communications (11.02.2021)
Published in Nature communications (11.02.2021)
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Journal Article
Plasma proteomics of acute tubular injury
Schmidt, Insa M., Surapaneni, Aditya L., Zhao, Runqi, Upadhyay, Dhairya, Yeo, Wan-Jin, Schlosser, Pascal, Huynh, Courtney, Srivastava, Anand, Palsson, Ragnar, Kim, Taesoo, Stillman, Isaac E., Barwinska, Daria, Barasch, Jonathan, Eadon, Michael T., El-Achkar, Tarek M., Henderson, Joel, Moledina, Dennis G., Rosas, Sylvia E., Claudel, Sophie E., Verma, Ashish, Wen, Yumeng, Lindenmayer, Maja, Huber, Tobias B., Parikh, Samir V., Shapiro, John P., Rovin, Brad H., Stanaway, Ian B., Sathe, Neha A., Bhatraju, Pavan K., Coresh, Josef, Rhee, Eugene P., Grams, Morgan E., Waikar, Sushrut S.
Published in Nature communications (27.08.2024)
Published in Nature communications (27.08.2024)
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Journal Article
Epigenome-wide DNA methylation in obsessive-compulsive disorder
Schiele, Miriam A., Lipovsek, Jan, Schlosser, Pascal, Soutschek, Michael, Schratt, Gerhard, Zaudig, Michael, Berberich, Götz, Köttgen, Anna, Domschke, Katharina
Published in Translational psychiatry (01.06.2022)
Published in Translational psychiatry (01.06.2022)
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Journal Article
Author Correction: Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism
Cheng, Yurong, Schlosser, Pascal, Hertel, Johannes, Sekula, Peggy, Oefner, Peter J., Spiekerkoetter, Ute, Mielke, Johanna, Freitag, Daniel F., Schmidts, Miriam, Kronenberg, Florian, Eckardt, Kai-Uwe, Thiele, Ines, Li, Yong, Köttgen, Anna
Published in Nature communications (06.10.2021)
Published in Nature communications (06.10.2021)
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Journal Article
Integrated proteomic and metabolomic modules identified as biomarkers of mortality in the Atherosclerosis Risk in Communities study and the African American Study of Kidney Disease and Hypertension
Zhou, Linda, Surapaneni, Aditya, Rhee, Eugene P, Yu, Bing, Boerwinkle, Eric, Coresh, Josef, Grams, Morgan E, Schlosser, Pascal
Published in Human genomics (03.11.2022)
Published in Human genomics (03.11.2022)
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Journal Article
GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS
Hoppmann, Anselm S, Schlosser, Pascal, Backofen, Rolf, Lausch, Ekkehart, Köttgen, Anna
Published in PloS one (09.09.2016)
Published in PloS one (09.09.2016)
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Journal Article
A genome-wide association study identifies 41 loci associated with eicosanoid levels
Rhee, Eugene P., Surapaneni, Aditya L., Schlosser, Pascal, Alotaibi, Mona, Yang, Yueh-ning, Coresh, Josef, Jain, Mohit, Cheng, Susan, Yu, Bing, Grams, Morgan E.
Published in Communications biology (31.07.2023)
Published in Communications biology (31.07.2023)
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Journal Article
Circulating Proteins and Mortality in CKD: A Proteomics Study of the AASK and ARIC Cohorts
Srialluri, Nityasree, Surapaneni, Aditya, Schlosser, Pascal, Chen, Teresa K., Schmidt, Insa M., Rhee, Eugene P., Coresh, Josef, Grams, Morgan E.
Published in Kidney medicine (01.10.2023)
Published in Kidney medicine (01.10.2023)
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Journal Article
38 Plasma proteomic signature of motoric cognitive risk syndrome
Gomez, Gabriela T., Sathyan, Sanish, Chen, Jingsha, Fornage, Myriam, Schlosser, Pascal, Peng, Zhongsheng, Cordon, Jenifer, Palta, Priya, Sullivan, Kevin J., Tin, Adrienne, Windham, B. Gwen, Gottesman, Rebecca F., Coresh, Josef, Barzilai, Nir, Milman, Sofiya, Verghese, Joe, Walker, Keenan A.
Published in Journal of clinical and translational science (01.04.2023)
Published in Journal of clinical and translational science (01.04.2023)
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Journal Article
Multiancestry Genome-Wide Association Meta-Analyses of Kidney Function Traits: The CKDGen Consortium R5 Project: FR-PO648
Ghasemi, Sahar, König, Eva, Gorski, Mathias, Schlosser, Pascal, Wuttke, Matthias
Published in Journal of the American Society of Nephrology (01.10.2024)
Published in Journal of the American Society of Nephrology (01.10.2024)
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Journal Article
Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies
Zhang, Jingning, Dutta, Diptavo, Köttgen, Anna, Tin, Adrienne, Schlosser, Pascal, Grams, Morgan E., Harvey, Benjamin, Yu, Bing, Boerwinkle, Eric, Coresh, Josef, Chatterjee, Nilanjan
Published in Nature genetics (01.05.2022)
Published in Nature genetics (01.05.2022)
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Journal Article
Proteomics: Progress and Promise of High-Throughput Proteomics in Chronic Kidney Disease
Schlosser, Pascal, Grams, Morgan E., Rhee, Eugene P.
Published in Molecular & cellular proteomics (01.06.2023)
Published in Molecular & cellular proteomics (01.06.2023)
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Journal Article
Network Analysis of Paired Plasma-Urine Metabolomes Reveals Genetic Determinants of Metabolite Clusters: TH-OR20
Schlosser, Pascal, Hackenberg, Maren, Monteiro-Martins, Sara, Haug, Stefan, Kottgen, Anna
Published in Journal of the American Society of Nephrology (01.10.2024)
Published in Journal of the American Society of Nephrology (01.10.2024)
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Journal Article