VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms
Zhang, Keman, Zakeri, Amin, Alban, Tyler, Dong, Juan, Ta, Hieu M., Zalavadia, Ajay H., Branicky, Andrelie, Zhao, Haoxin, Juric, Ivan, Husic, Hana, Parthasarathy, Prerana B., Rupani, Amit, Drazba, Judy A., Chakraborty, Abhishek A., Ching-Cheng Huang, Stanley, Chan, Timothy, Avril, Stefanie, Wang, Li Lily
Published in Cell reports (Cambridge) (23.01.2024)
Published in Cell reports (Cambridge) (23.01.2024)
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LRIG1 engages ligand VISTA and impairs tumor-specific CD8 + T cell responses
Ta, Hieu Minh, Roy, Dia, Zhang, Keman, Alban, Tyler, Juric, Ivan, Dong, Juan, Parthasarathy, Prerana B, Patnaik, Sachin, Delaney, Elizabeth, Gilmour, Cassandra, Zakeri, Amin, Shukla, Nidhi, Rupani, Amit, Phoon, Yee Peng, Liu, Caini, Avril, Stefanie, Gastman, Brian, Chan, Timothy, Wang, Li Lily
Published in Science immunology (17.05.2024)
Published in Science immunology (17.05.2024)
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Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity
Ma, Xiaoxiao, Riaz, Nadeem, Samstein, Robert M., Lee, Mark, Makarov, Vladimir, Valero, Cristina, Chowell, Diego, Kuo, Fengshen, Hoen, Douglas, Fitzgerald, Conall W. R., Jiang, Hui, Alektiar, Jonathan, Alban, Tyler J., Juric, Ivan, Parthasarathy, Prerana Bangalore, Zhao, Yu, Sabio, Erich Y., Verma, Richa, Srivastava, Raghvendra M., Vuong, Lynda, Yang, Wei, Zhang, Xiao, Wang, Jingming, Chu, Lawrence K., Wang, Stephen L., Kelly, Daniel W., Pei, Xin, Chen, Jiapeng, Yaeger, Rona, Zamarin, Dmitriy, Zehir, Ahmet, Gönen, Mithat, Morris, Luc G. T., Chan, Timothy A.
Published in Nature genetics (01.07.2022)
Published in Nature genetics (01.07.2022)
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Journal Article
935 VISTA regulates the differentiation of myeloid-derived suppressor cells by STAT3-dependent modulation of arginase-1 and iNOS expression and mitochondrial function
Zhang, Keman, Zakeri, Amin, Tyler, Alban, Dong, Juan, Ta, Hieu, Zalavadia, Ajay, Branicky, Andrelie, Zhao, Haoxin, Juric, Ivan, Husich, Hanna, Parthasarathy, Prerana, Rupani, Amit, Drazba, Judy, Chakraborty, Abhishek, Huang, Stanley, Chan, Timothy, Avril, Stefanie, Wang, Li
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Genomic landscape of superficial malignant peripheral nerve sheath tumor
McAfee, John L., Alban, Tyler J., Makarov, Vladimir, Rupani, Amit, Parthasarathy, Prerana B., Tu, Zheng, Ronen, Shira, Billings, Steven D., Diaz, C Marcela, Chan, Timothy A., Ko, Jennifer S.
Published in Laboratory investigation (01.11.2024)
Published in Laboratory investigation (01.11.2024)
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Topological heterogeneity of genomic and immunologic effects from combination immunotherapy treatment in the neoadjuvant setting for renal cell carcinoma (RCC)
Alban, Tyler, Singh, Salendra, Pavicic, Paul G., Rayman, Patricia A., Bangalore, Prerana Parthasarathy, Rupani, Amit, Makarov, Vladimir, Przybycin, Christopher, Ko, Jennifer S., Krishnamurthi, Venkatesh, Campbell, Steven, Chan, Timothy An-thy, Rini, Brian I., Diaz-Montero, C. Marcela, Ornstein, Moshe Chaim
Published in Journal of clinical oncology (01.02.2024)
Published in Journal of clinical oncology (01.02.2024)
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Leucine-rich repeats and immunoglobulin-like domains protein 1 is highly expressed on tumor-infiltrating T cells and may play a role in modulating T cell activation
Ta, Hieu M, Roy, Dia, Zhang, Keman, Dong, Juan, Gilmour, Cassandra, Yoo, Seong-Keun, Alban, Tyler, Makarov, Vladimir, Parthasarathy, Prerana Bangalore, Chan, Timothy, Wang, Li
Published in The Journal of immunology (1950) (01.05.2022)
Published in The Journal of immunology (1950) (01.05.2022)
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3043 – SEX-DEPENDENT NICHE RESPONSES MODULATE STEADY-STATE AND REGENERATIVE HEMATOPOIESIS
Chaudhary, Rahul, Smith, Julianne, Tiwari, Riya, Klein, Bailey, Cordova, Brittany, Petroze, Frederick, Richardson, Brian, Broncano, Alyssia, Lee, Juyeun, Parthasarathy, Prerana, De Carvalho, Karina, Cameron, Scott, Lathia, Justin, Goodman, Wendy, Cameron, Mark, Desai, Amar
Published in Experimental hematology (01.08.2024)
Published in Experimental hematology (01.08.2024)
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Genomic analysis from BLASST-1 (Bladder Cancer Signal Seeking Trial) of nivolumab, gemcitabine, and cisplatin in patients with MIBC undergoing cystectomy
Gupta, Shilpa, Makarov, Vladimir, Sonpavde, Guru P., Gibb, Ewan, Gupta, Sumati, Maughan, Benjamin L., Agarwal, Neeraj, Mossanen, Matthew, Thyagarajan, Bharat, Diaz-Montero, C. Marcela, Bangalore, Prerana Parthasarathy, Konety, Badrinath R.
Published in Journal of clinical oncology (20.02.2023)
Published in Journal of clinical oncology (20.02.2023)
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Neoantigen immunogenicity landscapes and evolution of tumor ecosystems during immunotherapy with nivolumab
Alban, Tyler J, Riaz, Nadeem, Parthasarathy, Prerana, Makarov, Vladimir, Kendall, Sviatoslav, Yoo, Seong-Keun, Shah, Rachna, Weinhold, Nils, Srivastava, Raghvendra, Ma, Xiaoxiao, Krishna, Chirag, Mok, Juk Yee, van Esch, Wim J E, Garon, Edward, Akerley, Wallace, Creelan, Benjamin, Aanur, Nivedita, Chowell, Diego, Geese, William J, Rizvi, Naiyer A, Chan, Timothy A
Published in Nature medicine (30.09.2024)
Published in Nature medicine (30.09.2024)
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Phase II Clinical Trial of Pembrolizumab and Chemotherapy Reveals Distinct Transcriptomic Profiles by Radiologic Response in Metastatic Triple-Negative Breast Cancer
Wilkerson, Avia D, Parthasarathy, Prerana Bangalore, Stabellini, Nickolas, Mitchell, Carley, Pavicic, Jr, Paul G, Fu, Pingfu, Rupani, Amit, Husic, Hana, Rayman, Patricia A, Swaidani, Shadi, Abraham, Jame, Budd, G Thomas, Moore, Halle, Al-Hilli, Zahraa, Ko, Jennifer S, Baar, Joseph, Chan, Timothy A, Alban, Tyler, Diaz-Montero, C Marcela, Montero, Alberto J
Published in Clinical cancer research (05.01.2024)
Published in Clinical cancer research (05.01.2024)
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Sex-dependent niche responses modulate steady-state and regenerative hematopoiesis
Chaudhary, Rahul, Smith, Julianne N.P., Tiwari, Riya, Klein, Bailey R., Cordova, Brittany A., Petroze, Frederick, Richardson, Brian, Broncano, Alyssia V., Lee, Juyeun, Parthasarathy, Prerana Bangalore, De Carvalho, Karina Inacio Ladislau, Cameron, Scott J., Lathia, Justin D., Goodman, Wendy A., Cameron, Mark J., Desai, Amar B.
Published in Experimental hematology (01.09.2024)
Published in Experimental hematology (01.09.2024)
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Unsupervised and supervised AI on molecular dynamics simulations reveals complex characteristics of HLA-A2-peptide immunogenicity
Weber, Jeffrey K, Morrone, Joseph A, Kang, Seung-Gu, Zhang, Leili, Lang, Lijun, Chowell, Diego, Krishna, Chirag, Huynh, Tien, Parthasarathy, Prerana, Luan, Binquan, Alban, Tyler J, Cornell, Wendy D, Chan, Timothy A
Published in Briefings in bioinformatics (01.01.2024)
Published in Briefings in bioinformatics (01.01.2024)
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Abstract 1358: Elucidating the contribution of T cell-intrinsic VISTA to the suppression of antitumor T cell immunity
Patnaik, Sachin, Delaney, Elizabeth, Gilmour, Cassandra, Zhang, Keman, Zakeri, Amin, Ta, Hieu M., Parthasarathy, Prerana B., Alban, Tyler, Chan, Timothy, Wang, Li Lily
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Sexually dimorphic computational histopathological signatures prognostic of overall survival in high-grade gliomas via deep learning
Verma, Ruchika, Alban, Tyler J, Parthasarathy, Prerana, Mokhtari, Mojgan, Toro Castano, Paula, Cohen, Mark L, Lathia, Justin D, Ahluwalia, Manmeet, Tiwari, Pallavi
Published in Science advances (23.08.2024)
Published in Science advances (23.08.2024)
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Abstract 1125: Neoantigen immunogenicity landscapes and evolution of tumor ecosystems during immunotherapy with nivolumab
Alban, Tyler Joseph, Riaz, Nadeem, Parthasarathy, Prerana, Makarov, Vlad, Kendall, Slav, Yoo, Seong-Keun, Shah, Rachna, Weinhold, Nils, Srivastava, Raghvendra, Ma, Xiaoxiao, Krishna, Chirag, Garon, Edward, Akerley, Wallace, Creelan, Ben, Aanuren, Nivedita, Chowell, Diego, Geese, William, Rizvi, Naiyer, Chan, Timothy
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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