32-Indolyl Ether Derivatives of Ascomycin: Three-Dimensional Structures of Complexes with FK506-Binding Protein
Becker, Joseph W, Rotonda, Jennifer, Cryan, John G, Martin, Mary, Parsons, William H, Sinclair, Peter J, Wiederrecht, Greg, Wong, Frederick
Published in Journal of medicinal chemistry (29.07.1999)
Published in Journal of medicinal chemistry (29.07.1999)
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A tacrolimus-related immunosuppressant with reduced toxicity
Dumont, F J, Koprak, S, Staruch, M J, Talento, A, Koo, G, DaSilva, C, Sinclair, P J, Wong, F, Woods, J, Barker, J, Pivnichny, J, Singer, I, Sigal, N H, Williamson, A R, Parsons, W H, Wyvratt, M
Published in Transplantation (15.01.1998)
Published in Transplantation (15.01.1998)
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A tacrolimus-related immunosuppressant with biochemical properties distinct from those of tacrolimus
Peterson, L B, Cryan, J G, Rosa, R, Martin, M M, Wilusz, M B, Sinclair, P J, Wong, F, Parsons, J N, O'Keefe, S J, Parsons, W H, Wyvratt, M, Sigal, N H, Williamson, A R, Wiederrecht, G J
Published in Transplantation (15.01.1998)
Published in Transplantation (15.01.1998)
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Journal Article
Phosphinic acid inhibitors of D-alanyl-D-alanine ligase
Parsons, William H, Patchett, Arthur A, Bull, Herbert G, Schoen, William R, Taub, David, Davidson, Jacqueline, Combs, Patricia L, Springer, James P, Gadebusch, Hans
Published in Journal of medicinal chemistry (01.09.1988)
Published in Journal of medicinal chemistry (01.09.1988)
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Journal Article
(3-Amino-2-oxoalkyl)phosphonic acids and their analogs as novel inhibitors of D-alanine:D-alanine ligase
Chakravarty, Prasun K, Greenlee, William J, Parsons, William H, Patchett, Arthur A, Combs, Patricia, Roth, Alan, Busch, Robert D, Mellin, Theodore N
Published in Journal of medicinal chemistry (01.08.1989)
Published in Journal of medicinal chemistry (01.08.1989)
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Journal Article
C32-O-imidazol-2-yl-methyl ether derivatives of the immunosuppressant ascomycin with improved therapeutic potential
Goulet, Mark T., McAlpine, Shelli R., Staruch, Mary Jo, Koprak, Samuel, Dumont, Francis J., Cryan, John G., Wiederrecht, Gregory J., Rosa, Raymond, Wilusz, Mary Beth, Peterson, Laurence B., Wyvratt, Matthew J., Parsons, William H.
Published in Bioorganic & medicinal chemistry letters (18.08.1998)
Published in Bioorganic & medicinal chemistry letters (18.08.1998)
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Development, synthesis, and biological evaluation of (-)-trans-(2S,5S)-2-[3-[(2-oxopropyl)sulfonyl]-4-n-propoxy-5-(3-hydroxypropoxy)-phenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, a potent orally active platelet-activating factor (PAF) antagonist and its water-soluble prodrug phosphate ester
Girotra, N. N, Biftu, T, Ponpipom, M. M, Acton, J. J, Alberts, A. W, Bach, T. N, Ball, R. G, Bugianesi, R. L, Chabala, J. C
Published in Journal of medicinal chemistry (01.09.1992)
Published in Journal of medicinal chemistry (01.09.1992)
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Journal Article
C32-O-phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study
Goulet, Mark T., Sinclair, Peter J., Wong, Frederick, Staruch, Mary Jo, Dumont, Francis J., Cryan, John G., Wiederrecht, Gregory J., Wyvratt, Matthew J., Parsons, William H.
Published in Bioorganic & medicinal chemistry letters (19.07.1999)
Published in Bioorganic & medicinal chemistry letters (19.07.1999)
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Journal Article
Design and synthesis of P2-P1'-linked macrocyclic human renin inhibitors
Weber, Ann E, Halgren, Thomas A, Doyle, John J, Lynch, Robert J, Siegl, Peter K. S, Parsons, William H, Greenlee, William J, Patchett, Arthur A
Published in Journal of medicinal chemistry (01.09.1991)
Published in Journal of medicinal chemistry (01.09.1991)
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Journal Article
Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity
Armstrong, Helen M., Wong, Frederick, Holmes, Mark A., Sinclair, Peter J., Goulet, Mark T., Dumont, Francis J., Staruch, MaryJo, Koprak, Samuel, Peterson, Laurence B., Rosa, Raymond, Wilusz, Mary Beth, Wiederrecht, Gregory J., Cryan, John G., Wyvratt, Matthew J., Parsons, William H.
Published in Bioorganic & medicinal chemistry letters (19.07.1999)
Published in Bioorganic & medicinal chemistry letters (19.07.1999)
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Journal Article
Structure-Activity Relationships of C1 and C6 Side Chains of Zaragozic Acid A Derivatives
Ponpipom, Mitree M., Girotra, Narindar N., Bugianesi, Robert L., Roberts, Cathleen D., Berger, Gregory D., Burk, Robert M., Marquis, Robert W., Parsons, William H., Bartizal, Kenneth F.
Published in Journal of medicinal chemistry (01.11.1994)
Published in Journal of medicinal chemistry (01.11.1994)
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Journal Article
The synthesis of C3-methyl, C3-decarboxy-zaragozic acid A — A potent squalene synthase inhibitor
Kuo, C.H., Plevyak, S.P., Biftu, T., Parsons, W.H., Berger, G.D.
Published in Tetrahedron letters (22.10.1993)
Published in Tetrahedron letters (22.10.1993)
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Journal Article
Selective Protection and Relative Importance of the Carboxylic Acid Groups of Zaragozic Acid A for Squalene Synthase Inhibition
Biftu, Tesfaye, Acton, John J, Berger, Gregory D, Bergstrom, James D, Dufresne, Claude, Kurtz, Marc M, Marquis, Robert W, Parsons, William H, Rew, Deborah R, Wilson, Kenneth E
Published in Journal of medicinal chemistry (01.02.1994)
Published in Journal of medicinal chemistry (01.02.1994)
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Journal Article
Identification and Biochemical Characterization of a Novel Nortriterpene Inhibitor of the Human Lymphocyte Voltage-Gated Potassium Channel, Kv1.3
Felix, John P, Bugianesi, Randal M, Schmalhofer, William A, Borris, Robert, Goetz, Michael A, Hensens, Otto D, Bao, Jian-Ming, Kayser, Frank, Parsons, William H, Rupprecht, Kathleen, Garcia, Maria L, Kaczorowski, Gregory J, Slaughter, Robert S
Published in Biochemistry (Easton) (20.04.1999)
Published in Biochemistry (Easton) (20.04.1999)
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Block of Peripheral Nerve Sodium Channels Selectively Inhibits Features of Neuropathic Pain in Rats
Brochu, Richard M, Dick, Ivy E, Tarpley, Jason W, McGowan, Erin, Gunner, David, Herrington, James, Shao, Pengcheng P, Ok, Dong, Li, Chunshi, Parsons, William H, Stump, Gary L, Regan, Christopher P, Lynch, Jr, Joseph J, Lyons, Kathryn A, McManus, Owen B, Clark, Samantha, Ali, Zahid, Kaczorowski, Gregory J, Martin, William J, Priest, Birgit T
Published in Molecular pharmacology (01.03.2006)
Published in Molecular pharmacology (01.03.2006)
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Journal Article
Correolide and Derivatives Are Novel Immunosuppressants Blocking the Lymphocyte Kv1.3 Potassium Channels
Koo, Gloria C., Blake, Joseph T., Shah, Kashmira, Staruch, Mary Jo, Dumont, Francis, Wunderler, Denise, Sanchez, Manuel, McManus, Owen B., Sirotina-Meisher, Anna, Fischer, Paul, Boltz, Robert C., Goetz, Michael A., Baker, Robert, Bao, Jianming, Kayser, Frank, Rupprecht, Kathleen M., Parsons, William H., Tong, Xin-Chun, Ita, Ida E., Pivnichny, Jim, Vincent, Stella, Cunningham, Paul, Hora, Don, Feeney, William, Kaczorowski, Gregory, Springer, Martin S.
Published in Cellular immunology (01.11.1999)
Published in Cellular immunology (01.11.1999)
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Journal Article
A total synthesis of dl-pentalenolactone
Parsons, W. H, Schlessinger, R. H, Quesada, Martha L
Published in Journal of the American Chemical Society (01.01.1980)
Published in Journal of the American Chemical Society (01.01.1980)
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Journal Article
Benzolactams. A new class of converting enzyme inhibitors
Parsons, W.H., Davidson, J.L., Taub, D., Aster, S.D., Thorsett, E.D., Patchett, A.A., Ulm, E.H., Lamont, B.I.
Published in Biochemical and biophysical research communications (30.11.1983)
Published in Biochemical and biophysical research communications (30.11.1983)
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