Cholinergic Differentiation of Human Neuroblastoma SH-SY5Y Cell Line and Its Potential Use as an In vitro Model for Alzheimer’s Disease Studies
de Medeiros, Liana M., De Bastiani, Marco A., Rico, Eduardo P., Schonhofen, Patrícia, Pfaffenseller, Bianca, Wollenhaupt-Aguiar, Bianca, Grun, Lucas, Barbé-Tuana, Florência, Zimmer, Eduardo R., Castro, Mauro A. A., Parsons, Richard B., Klamt, Fábio
Published in Molecular neurobiology (01.11.2019)
Published in Molecular neurobiology (01.11.2019)
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Nicotinamide N-methyltransferase increases complex I activity in SH-SY5Y cells via sirtuin 3
Liu, Karolina Y., Mistry, Rakhee J., Aguirre, Carlos A., Fasouli, Eirini S., Thomas, Martin G., Klamt, Fábio, Ramsden, David B., Parsons, Richard B.
Published in Biochemical and biophysical research communications (20.11.2015)
Published in Biochemical and biophysical research communications (20.11.2015)
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The expression of nicotinamide N-methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of Complex I inhibitors
Parsons, Richard B, Aravindan, Shylesh, Kadampeswaran, Anusha, Evans, Emily A, Sandhu, Kanwaljeet K, Levy, Elizabeth R, Thomas, Martin G, Austen, Brian M, Ramsden, David B
Published in Biochemical journal (15.05.2011)
Published in Biochemical journal (15.05.2011)
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Cannabidiol Exposure During Neuronal Differentiation Sensitizes Cells Against Redox-Active Neurotoxins
Schönhofen, Patrícia, de Medeiros, Liana M., Bristot, Ivi Juliana, Lopes, Fernanda M., De Bastiani, Marco A., Kapczinski, Flávio, Crippa, José Alexandre S., Castro, Mauro Antônio A., Parsons, Richard B., Klamt, Fábio
Published in Molecular neurobiology (01.08.2015)
Published in Molecular neurobiology (01.08.2015)
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Potent Inhibition of Nicotinamide N‑Methyltransferase by Alkene-Linked Bisubstrate Mimics Bearing Electron Deficient Aromatics
Gao, Yongzhi, van Haren, Matthijs J, Buijs, Ned, Innocenti, Paolo, Zhang, Yurui, Sartini, Davide, Campagna, Roberto, Emanuelli, Monica, Parsons, Richard B, Jespers, Willem, Gutiérrez-de-Terán, Hugo, van Westen, Gerard J. P, Martin, Nathaniel I
Published in Journal of medicinal chemistry (09.09.2021)
Published in Journal of medicinal chemistry (09.09.2021)
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Metabolic rewiring in melanoma drug-resistant cells
Bristot, Ivi Juliana, Kehl Dias, Camila, Chapola, Henrique, Parsons, Richard B., Klamt, Fábio
Published in Critical reviews in oncology/hematology (01.09.2020)
Published in Critical reviews in oncology/hematology (01.09.2020)
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A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration
Solomon, Daniel A, Stepto, Alan, Au, Wing Hei, Adachi, Yoshitsugu, Diaper, Danielle C, Hall, Rachel, Rekhi, Anjeet, Boudi, Adel, Tziortzouda, Paraskevi, Lee, Youn-Bok, Smith, Bradley, Bridi, Jessika C, Spinelli, Greta, Dearlove, Jonah, Humphrey, Dickon M, Gallo, Jean-Marc, Troakes, Claire, Fanto, Manolis, Soller, Matthias, Rogelj, Boris, Parsons, Richard B, Shaw, Christopher E, Hortobágyi, Tibor, Hirth, Frank
Published in Brain (London, England : 1878) (01.10.2018)
Published in Brain (London, England : 1878) (01.10.2018)
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Alpha-synucleinopathy reduces NMNAT3 protein levels and neurite formation that can be rescued by targeting the NAD+ pathway
Parsons, Richard B, Kocinaj, Altin, Ruiz Pulido, Gustavo, Prendergast, Sarah A, Parsons, Anna E, Facey, Paul D, Hirth, Frank
Published in Human molecular genetics (25.08.2022)
Published in Human molecular genetics (25.08.2022)
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A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N‑Methyltransferase
van Haren, Matthijs J, Sastre Toraño, Javier, Sartini, Davide, Emanuelli, Monica, Parsons, Richard B, Martin, Nathaniel I
Published in Biochemistry (Easton) (20.09.2016)
Published in Biochemistry (Easton) (20.09.2016)
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Cannabinoid-Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System
Schonhofen, Patrícia, Bristot, Ivi Juliana, Crippa, José Alexandre, Hallak, Jaime Eduardo Cecílio, Zuardi, Antônio Waldo, Parsons, Richard B., Klamt, Fábio
Published in CNS drugs (01.08.2018)
Published in CNS drugs (01.08.2018)
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Plasma Therapy to Prevent Severe Covid-19 in Older Adults
Klamt, Fábio, Parsons, Richard B, Jones, Marcus H, Ragusa, Martin, Tortosa, Fernando, Izcovich, Ariel, Wappner, Diego, Bergel, Eduardo, Polack, Fernando P
Published in The New England journal of medicine (24.06.2021)
Published in The New England journal of medicine (24.06.2021)
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High Expression of Nicotinamide N-Methyltransferase in Patients with Sporadic Alzheimer’s Disease
Kocinaj, Altin, Chaudhury, Tabassum, Uddin, Mohammed S., Junaid, Rashad R., Ramsden, David B., Hondhamuni, Geshanthi, Klamt, Fábio, Parsons, Linda, Parsons, Richard B.
Published in Molecular neurobiology (01.04.2021)
Published in Molecular neurobiology (01.04.2021)
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Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state
van Haren, Matthijs J., Taig, Rebecca, Kuppens, Jilles, Torano, Javier Sastre, Moret, E. D. E., Parsons, Richard B., Sartini, Davide, Emanuellic, Monica, Martin, Nathaniel I.
Published in Organic & biomolecular chemistry (09.08.2017)
Published in Organic & biomolecular chemistry (09.08.2017)
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The effect of foetal bovine serum supplementation upon the lactate dehydrogenase cytotoxicity assay: Important considerations for in vitro toxicity analysis
Thomas, Martin G., Marwood, Roxanne M., Parsons, Anna E., Parsons, Richard B.
Published in Toxicology in vitro (25.12.2015)
Published in Toxicology in vitro (25.12.2015)
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Mimicking Parkinson’s Disease in a Dish: Merits and Pitfalls of the Most Commonly used Dopaminergic In Vitro Models
Lopes, Fernanda Martins, Bristot, Ivi Juliana, da Motta, Leonardo Lisbôa, Parsons, Richard B., Klamt, Fabio
Published in Neuromolecular medicine (01.09.2017)
Published in Neuromolecular medicine (01.09.2017)
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