Intratumoral expression of IL-12 from lentiviral or RNA vectors acts synergistically with TLR4 agonist (GLA) to generate anti-tumor immunological memory
Leleux, Jardin A, Albershardt, Tina C, Reeves, Rebecca, James, Reice, Krull, Jordan, Parsons, Andrea J, Ter Meulen, Jan, Berglund, Peter
Published in PloS one (02.12.2021)
Published in PloS one (02.12.2021)
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Targeting Antigen to the Surface of EVs Improves the In Vivo Immunogenicity of Human and Non-human Adenoviral Vaccines in Mice
Bliss, Carly M., Parsons, Andrea J., Nachbagauer, Raffael, Hamilton, Jennifer R., Cappuccini, Federica, Ulaszewska, Marta, Webber, Jason P., Clayton, Aled, Hill, Adrian V.S., Coughlan, Lynda
Published in Molecular therapy. Methods & clinical development (13.03.2020)
Published in Molecular therapy. Methods & clinical development (13.03.2020)
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Journal Article
Development of broadly neutralizing antibodies targeting the cytomegalovirus subdominant antigen gH
Parsons, Andrea J, Ophir, Sabrina I, Duty, J Andrew, Kraus, Thomas A, Stein, Kathryn R, Moran, Thomas M, Tortorella, Domenico
Published in Communications biology (25.04.2022)
Published in Communications biology (25.04.2022)
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A broadly neutralizing human monoclonal antibody generated from transgenic mice immunized with HCMV particles limits virus infection and proliferation
Atanasoff, Kristina E., Parsons, Andrea J., Ophir, Sabrina I., Lurain, Nell, Kraus, Thomas, Moran, Thomas, Duty, J. Andrew, Tortorella, Domenico
Published in Journal of virology (23.07.2024)
Published in Journal of virology (23.07.2024)
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Journal Article
ZVex™, a dendritic-cell-tropic lentivector, primes protective antitumor T cell responses that are significantly boosted using heterologous vaccine modalities
Leleux, Jardin A., Albershardt, Tina C., Parsons, Andrea J., ter Meulen, Jan, Berglund, Peter
Published in Vaccine (22.09.2020)
Published in Vaccine (22.09.2020)
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Journal Article
Valspodar limits human cytomegalovirus infection and dissemination
Parsons, Andrea J., Cohen, Tobias, Schwarz, Toni M., Stein, Kathryn R., Ophir, Sabrina I., Casado, Jailene Paredes, Tortorella, Domenico
Published in Antiviral research (01.09.2021)
Published in Antiviral research (01.09.2021)
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Journal Article
Investigating N-arylpyrimidinamine (NAPA) compounds as early-stage inhibitors against human cytomegalovirus
Parsons, Andrea J., Ophir, Sabrina I., Gardner, Thomas J., Paredes, Jailene Casado, Stein, Kathryn R., Kwasny, Steven M., Cardinale, Steven C., Torhan, Matthew, Prichard, Mark N., James, Scott H., Atanasoff, Kristina E., G-Dayanandan, Narendran, Bowlin, Terry L., Opperman, Timothy J., Tortorella, Domenico
Published in Antiviral research (01.01.2023)
Published in Antiviral research (01.01.2023)
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Abstract 4884: Intratumoral expression of IL-12 from a dendritic cell-targeting chimeric lentiviral vector from the ZVex platform cures established tumors in multiple models and induces systemic anti-tumor responses
Albershardt, Tina C., Bajaj, Anshika, Archer, Jacob F., Reeves, Rebecca S., Parsons, Andrea J., Ngo, Lisa Y., ter Meulen, Jan, Berglund, Peter
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Intratumoral expression of IL-12 from lentiviral or RNA vectors acts synergistically with TLR4 agonist
Leleux, Jardin A, Albershardt, Tina C, Reeves, Rebecca, James, Reice, Krull, Jordan, Parsons, Andrea J, ter Meulen, Jan, Berglund, Peter
Published in PloS one (02.12.2021)
Published in PloS one (02.12.2021)
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Journal Article
Abstract 5673: Large established B16 tumors in mice are eradicated by ZVex® (dendritic cell-targeting lentiviral vector) and G100 (TLR4 agonist) combination immunotherapy through increasing tumor-infiltrating effector T cells and inducing antigen spreading
Albershardt, Tina C., Parsons, Andrea J., Leleux, Jardin, Berglund, Peter, Meulen, Jan ter
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Intratumoral injections of G100
Berglund, Peter, Parsons, Andrea J, ter Meulen, Jan, Albershardt, Tina C
Published in Journal for immunotherapy of cancer (04.11.2015)
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Published in Journal for immunotherapy of cancer (04.11.2015)
Journal Article
Intratumoral injections of G100 (synthetic TLR4 agonist) increase trafficking of lentiviral vector-induced antigen-specific CD8 T cells to the tumor microenvironment
Albershardt, Tina C, Parsons, Andrea J, Berglund, Peter, ter Meulen, Jan
Published in Journal for immunotherapy of cancer (04.11.2015)
Published in Journal for immunotherapy of cancer (04.11.2015)
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Journal Article
Checkpoint inhibitors synergize with therapeutic platforms, ZVex™ and GLAAS™ by enhancing lentiviral vector-induced tumor-specific immunity and adjuvant-mediated anti-tumor efficacy
Albershardt, Tina C, Parsons, Andrea J, ter Meulen, Jan, Berglund, Peter
Published in Journal for immunotherapy of cancer (04.11.2015)
Published in Journal for immunotherapy of cancer (04.11.2015)
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Journal Article
A "prime-pull" immunotherapy approach using a lentiviral vector and intratumoral TLR4 agonist redirects cytotoxic T cells
Albershardt, Tina C, Parsons, Andrea J, Flynn, Patrick, Berglund, Peter, ter Meulen, Jan
Published in Journal for immunotherapy of cancer (06.11.2014)
Published in Journal for immunotherapy of cancer (06.11.2014)
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Journal Article