Microvasculopathy in spinal muscular atrophy is driven by a reversible autonomous endothelial cell defect
Zhou, Haiyan, Hong, Ying, Scoto, Mariacristina, Thomson, Alison, Pead, Emma, MacGillivray, Tom, Hernandez-Gerez, Elena, Catapano, Francesco, Meng, Jinhong, Zhang, Qiang, Hunter, Gillian, Shorrock, Hannah K, Ng, Thomas K, Hamida, Abedallah, Sanson, Mathilde, Baranello, Giovanni, Howell, Kevin, Gillingwater, Thomas H, Brogan, Paul, Thompson, Dorothy A, Parson, Simon H, Muntoni, Francesco
Published in The Journal of clinical investigation (01.11.2022)
Published in The Journal of clinical investigation (01.11.2022)
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Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment
Sintusek, Palittiya, Catapano, Francesco, Angkathunkayul, Napat, Marrosu, Elena, Parson, Simon H, Morgan, Jennifer E, Muntoni, Francesco, Zhou, Haiyan
Published in PloS one (10.05.2016)
Published in PloS one (10.05.2016)
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Abnormal fatty acid metabolism is a core component of spinal muscular atrophy
Deguise, Marc‐Olivier, Baranello, Giovanni, Mastella, Chiara, Beauvais, Ariane, Michaud, Jean, Leone, Alessandro, De Amicis, Ramona, Battezzati, Alberto, Dunham, Christopher, Selby, Kathryn, Warman Chardon, Jodi, McMillan, Hugh J., Huang, Yu‐Ting, Courtney, Natalie L., Mole, Alannah J., Kubinski, Sabrina, Claus, Peter, Murray, Lyndsay M., Bowerman, Melissa, Gillingwater, Thomas H., Bertoli, Simona, Parson, Simon H., Kothary, Rashmi
Published in Annals of clinical and translational neurology (01.08.2019)
Published in Annals of clinical and translational neurology (01.08.2019)
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The Relationship between Body Composition, Fatty Acid Metabolism and Diet in Spinal Muscular Atrophy
Watson, Katherine S, Boukhloufi, Imane, Bowerman, Melissa, Parson, Simon H
Published in Brain sciences (20.01.2021)
Published in Brain sciences (20.01.2021)
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SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy
Wishart, Thomas M., Huang, Jack P.-W., Murray, Lyndsay M., Lamont, Douglas J., Mutsaers, Chantal A., Ross, Jenny, Geldsetzer, Pascal, Ansorge, Olaf, Talbot, Kevin, Parson, Simon H., Gillingwater, Thomas H.
Published in Human molecular genetics (01.11.2010)
Published in Human molecular genetics (01.11.2010)
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Morphological characteristics of motor neurons do not determine their relative susceptibility to degeneration in a mouse model of severe spinal muscular atrophy
Thomson, Sophie R, Nahon, Joya E, Mutsaers, Chantal A, Thomson, Derek, Hamilton, Gillian, Parson, Simon H, Gillingwater, Thomas H
Published in PloS one (20.12.2012)
Published in PloS one (20.12.2012)
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Induction of cell stress in neurons from transgenic mice expressing yellow fluorescent protein: implications for neurodegeneration research
Comley, Laura H, Wishart, Thomas M, Baxter, Becki, Murray, Lyndsay M, Nimmo, Ailish, Thomson, Derek, Parson, Simon H, Gillingwater, Thomas H
Published in PloS one (08.03.2011)
Published in PloS one (08.03.2011)
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Tissue quality assessment using a novel direct elasticity assessment device (the E-finger): a cadaveric study of prostatectomy dissection
Good, Daniel W, Khan, Ashfaq, Hammer, Steven, Scanlan, Paul, Shu, Wenmiao, Phipps, Simon, Parson, Simon H, Stewart, Grant D, Reuben, Robert, McNeill, S Alan
Published in PloS one (10.11.2014)
Published in PloS one (10.11.2014)
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COVID‐19 and anatomy: Stimulus and initial response
Brassett, Cecilia, Cosker, Thomas, Davies, D. Ceri, Dockery, Peter, Gillingwater, Thomas H., Lee, T. Clive, Milz, Stefan, Parson, Simon H., Quondamatteo, Fabio, Wilkinson, Tracey
Published in Journal of anatomy (01.09.2020)
Published in Journal of anatomy (01.09.2020)
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A role for spinal cord hypoxia in neurodegeneration
Hernandez-Gerez, Elena, Fleming, Ian N., Parson, Simon H.
Published in Cell death & disease (13.11.2019)
Published in Cell death & disease (13.11.2019)
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Vascular Defects and Spinal Cord Hypoxia in Spinal Muscular Atrophy
Somers, Eilidh, Lees, Robert D., Hoban, Katie, Sleigh, James N., Zhou, Haiyan, Muntoni, Francesco, Talbot, Kevin, Gillingwater, Thomas H., Parson, Simon H.
Published in Annals of neurology (01.02.2016)
Published in Annals of neurology (01.02.2016)
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Renal pathology in a mouse model of severe Spinal Muscular Atrophy is associated with downregulation of Glial Cell-Line Derived Neurotrophic Factor (GDNF)
Allardyce, Hazel, Kuhn, Daniela, Hernandez-Gerez, Elena, Hensel, Niko, Huang, Yu-Ting, Faller, Kiterie, Gillingwater, Thomas H, Quondamatteo, Fabio, Claus, Peter, Parson, Simon H
Published in Human molecular genetics (11.08.2020)
Published in Human molecular genetics (11.08.2020)
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Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy
Wishart, Thomas M, Mutsaers, Chantal A, Riessland, Markus, Reimer, Michell M, Hunter, Gillian, Hannam, Marie L, Eaton, Samantha L, Fuller, Heidi R, Roche, Sarah L, Somers, Eilidh, Morse, Robert, Young, Philip J, Lamont, Douglas J, Hammerschmidt, Matthias, Joshi, Anagha, Hohenstein, Peter, Morris, Glenn E, Parson, Simon H, Skehel, Paul A, Becker, Thomas, Robinson, Iain M, Becker, Catherina G, Wirth, Brunhilde, Gillingwater, Thomas H
Published in The Journal of clinical investigation (01.04.2014)
Published in The Journal of clinical investigation (01.04.2014)
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Exploring variation in surgical practice: does surgeon personality influence anastomotic decision-making?
Bisset, Carly N, Ferguson, Eamonn, MacDermid, Ewan, Stein, Sharon L, Yassin, Nuha, Dames, Nicola, Keller, Deborah S, Oliphant, Raymond, Parson, Simon H, Cleland, Jennifer, Moug, Susan J
Published in British journal of surgery (14.10.2022)
Published in British journal of surgery (14.10.2022)
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Survival of motor neurone protein is required for normal postnatal development of the spleen
Thomson, Alison K., Somers, Eilidh, Powis, Rachael A., Shorrock, Hannah K., Murphy, Kelley, Swoboda, Kathryn J., Gillingwater, Thomas H., Parson, Simon H.
Published in Journal of anatomy (01.02.2017)
Published in Journal of anatomy (01.02.2017)
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Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy
Leow, Damien Meng-Kiat, Ng, Yang Kai, Wang, Loo Chien, Koh, Hiromi Wl, Zhao, Tianyun, Khong, Zi Jian, Tabaglio, Tommaso, Narayanan, Gunaseelan, Giadone, Richard M, Sobota, Radoslaw M, Ng, Shi-Yan, Teo, Adrian Kk, Parson, Simon H, Rubin, Lee L, Ong, Wei-Yi, Darras, Basil T, Yeo, Crystal Jj
Published in The Journal of clinical investigation (15.06.2024)
Published in The Journal of clinical investigation (15.06.2024)
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