Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells
Lucas, Beth, White, Andrea J, Cosway, Emilie J, Parnell, Sonia M, James, Kieran D, Jones, Nick D, Ohigashi, Izumi, Takahama, Yousuke, Jenkinson, William E, Anderson, Graham
Published in Nature communications (04.05.2020)
Published in Nature communications (04.05.2020)
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Failures in thymus medulla regeneration during immune recovery cause tolerance loss and prime recipients for auto-GVHD
Alawam, Abdullah S, Cosway, Emilie J, James, Kieran D, Lucas, Beth, Bacon, Andrea, Parnell, Sonia M, White, Andrea J, Jenkinson, William E, Anderson, Graham
Published in The Journal of experimental medicine (07.02.2022)
Published in The Journal of experimental medicine (07.02.2022)
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Redefining thymus medulla specialization for central tolerance
Cosway, Emilie J, Lucas, Beth, James, Kieran D, Parnell, Sonia M, Carvalho-Gaspar, Manuela, White, Andrea J, Tumanov, Alexei V, Jenkinson, William E, Anderson, Graham
Published in The Journal of experimental medicine (06.11.2017)
Published in The Journal of experimental medicine (06.11.2017)
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An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells
White, Andrea J, Jenkinson, William E, Cowan, Jennifer E, Parnell, Sonia M, Bacon, Andrea, Jones, Nick D, Jenkinson, Eric J, Anderson, Graham
Published in The Journal of immunology (1950) (15.03.2014)
Published in The Journal of immunology (1950) (15.03.2014)
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Assembling the thymus medulla: Development and function of epithelial cell heterogeneity
James, Kieran D., Cosway, Emilie J., Parnell, Sonia M., White, Andrea J., Jenkinson, William E., Anderson, Graham
Published in BioEssays (01.03.2024)
Published in BioEssays (01.03.2024)
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Journal Article
The alarmin IL33 orchestrates type 2 immune-mediated control of thymus regeneration
Cosway, Emilie J, James, Kieran D, White, Andrea J, Parnell, Sonia M, Bacon, Andrea, McKenzie, Andrew N J, Jenkinson, W E, Anderson, Graham
Published in Nature communications (08.11.2023)
Published in Nature communications (08.11.2023)
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The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development
Cowan, Jennifer E, Parnell, Sonia M, Nakamura, Kyoko, Caamano, Jorge H, Lane, Peter J L, Jenkinson, Eric J, Jenkinson, William E, Anderson, Graham
Published in The Journal of experimental medicine (08.04.2013)
Published in The Journal of experimental medicine (08.04.2013)
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Embryonic keratin19 + progenitors generate multiple functionally distinct progeny to maintain epithelial diversity in the adult thymus medulla
Lucas, Beth, White, Andrea J, Klein, Fabian, Veiga-Villauriz, Clara, Handel, Adam, Bacon, Andrea, Cosway, Emilie J, James, Kieran D, Parnell, Sonia M, Ohigashi, Izumi, Takahama, Yousuke, Jenkinson, William E, Hollander, Georg A, Lu, Wei-Yu, Anderson, Graham
Published in Nature communications (12.04.2023)
Published in Nature communications (12.04.2023)
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Journal Article
A type 2 cytokine axis for thymus emigration
White, Andrea J, Baik, Song, Parnell, Sonia M, Holland, Amanda M, Brombacher, Frank, Jenkinson, William E, Anderson, Graham
Published in The Journal of experimental medicine (07.08.2017)
Published in The Journal of experimental medicine (07.08.2017)
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RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla
Rossi, Simona W, Kim, Mi-Yeon, Leibbrandt, Andreas, Parnell, Sonia M, Jenkinson, William E, Glanville, Stephanie H, McConnell, Fiona M, Scott, Hamish S, Penninger, Josef M, Jenkinson, Eric J, Lane, Peter J L, Anderson, Graham
Published in The Journal of experimental medicine (11.06.2007)
Published in The Journal of experimental medicine (11.06.2007)
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Rank Signaling Links the Development of Invariant γδ T Cell Progenitors and Aire+ Medullary Epithelium
Roberts, Natalie A., White, Andrea J., Jenkinson, William E., Turchinovich, Gleb, Nakamura, Kyoko, Withers, David R., McConnell, Fiona M., Desanti, Guillaume E., Benezech, Cecile, Parnell, Sonia M., Cunningham, Adam F., Paolino, Magdalena, Penninger, Josef M., Simon, Anna Katharina, Nitta, Takeshi, Ohigashi, Izumi, Takahama, Yousuke, Caamano, Jorge H., Hayday, Adrian C., Lane, Peter J.L., Jenkinson, Eric J., Anderson, Graham
Published in Immunity (Cambridge, Mass.) (23.03.2012)
Published in Immunity (Cambridge, Mass.) (23.03.2012)
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Aire controls the recirculation of murine Foxp3+ regulatory T‐cells back to the thymus
Cowan, Jennifer E., Baik, Song, McCarthy, Nicholas I., Parnell, Sonia M., White, Andrea J., Jenkinson, William E., Anderson, Graham
Published in European journal of immunology (01.05.2018)
Published in European journal of immunology (01.05.2018)
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Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7 + Progenitors to the Thymus
Cosway, Emilie J, Ohigashi, Izumi, Schauble, Karin, Parnell, Sonia M, Jenkinson, William E, Luther, Sanjiv, Takahama, Yousuke, Anderson, Graham
Published in The Journal of immunology (1950) (15.07.2018)
Published in The Journal of immunology (1950) (15.07.2018)
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Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk
White, Andrea J, Parnell, Sonia M, Handel, Adam, Maio, Stefano, Bacon, Andrea, Cosway, Emilie J, Lucas, Beth, James, Kieran D, Cowan, Jennifer E, Jenkinson, William E, Hollander, Georg A, Anderson, Graham
Published in The Journal of immunology (1950) (01.01.2023)
Published in The Journal of immunology (1950) (01.01.2023)
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Journal Article
Lymphotoxin β Receptor Controls T Cell Progenitor Entry to the Thymus
Lucas, Beth, James, Kieran D, Cosway, Emilie J, Parnell, Sonia M, Tumanov, Alexi V, Ware, Carl F, Jenkinson, William E, Anderson, Graham
Published in The Journal of immunology (1950) (01.10.2016)
Published in The Journal of immunology (1950) (01.10.2016)
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Endothelial cells act as gatekeepers for LTβR-dependent thymocyte emigration
James, Kieran D, Cosway, Emilie J, Lucas, Beth, White, Andrea J, Parnell, Sonia M, Carvalho-Gaspar, Manuela, Tumanov, Alexei V, Anderson, Graham, Jenkinson, William E
Published in The Journal of experimental medicine (03.12.2018)
Published in The Journal of experimental medicine (03.12.2018)
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Journal Article
Checkpoints in the Development of Thymic Cortical Epithelial Cells
Shakib, Saba, Desanti, Guillaume E, Jenkinson, William E, Parnell, Sonia M, Jenkinson, Eric J, Anderson, Graham
Published in The Journal of immunology (1950) (01.01.2009)
Published in The Journal of immunology (1950) (01.01.2009)
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Journal Article
Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive alpha beta T Cells in the Adult Thymus
Cowan, Jennifer E, McCarthy, Nicholas I, Parnell, Sonia M, White, Andrea J, Bacon, Andrea, Serge, Arnauld, Irla, Magali, Lane, Peter JL, Jenkinson, Eric J, Jenkinson, William E, Anderson, Graham
Published in The Journal of immunology (1950) (01.08.2014)
Published in The Journal of immunology (1950) (01.08.2014)
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Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla
Desanti, Guillaume E, Cowan, Jennifer E, Baik, Song, Parnell, Sonia M, White, Andrea J, Penninger, Josef M, Lane, Peter J L, Jenkinson, Eric J, Jenkinson, William E, Anderson, Graham
Published in The Journal of immunology (1950) (15.12.2012)
Published in The Journal of immunology (1950) (15.12.2012)
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