Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses
Daher, Boutaina, Parks, Scott K, Durivault, Jerome, Cormerais, Yann, Baidarjad, Hanane, Tambutte, Eric, Pouysségur, Jacques, Vučetić, Milica
Published in Cancer research (Chicago, Ill.) (01.08.2019)
Published in Cancer research (Chicago, Ill.) (01.08.2019)
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Journal Article
Hypoxia and cellular metabolism in tumour pathophysiology
Parks, Scott K., Cormerais, Yann, Pouysségur, Jacques
Published in The Journal of physiology (15.04.2017)
Published in The Journal of physiology (15.04.2017)
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Journal Article
pH control mechanisms of tumor survival and growth
Parks, Scott K., Chiche, Johanna, Pouyssegur, Jacques
Published in Journal of cellular physiology (01.02.2011)
Published in Journal of cellular physiology (01.02.2011)
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Journal Article
The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5)
Cormerais, Yann, Massard, Pierre André, Vucetic, Milica, Giuliano, Sandy, Tambutté, Eric, Durivault, Jerome, Vial, Valérie, Endou, Hitoshi, Wempe, Michael F., Parks, Scott K., Pouyssegur, Jacques
Published in The Journal of biological chemistry (23.02.2018)
Published in The Journal of biological chemistry (23.02.2018)
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Journal Article
Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth
Cormerais, Yann, Giuliano, Sandy, LeFloch, Renaud, Front, Benoît, Durivault, Jerome, Tambutté, Eric, Massard, Pierre-André, de la Ballina, Laura Rodriguez, Endou, Hitoshi, Wempe, Michael F, Palacin, Manuel, Parks, Scott K, Pouyssegur, Jacques
Published in Cancer research (Chicago, Ill.) (01.08.2016)
Published in Cancer research (Chicago, Ill.) (01.08.2016)
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Journal Article
Hypoxia optimises tumour growth by controlling nutrient import and acidic metabolite export
Parks, Scott K., Cormerais, Yann, Marchiq, Ibtissam, Pouyssegur, Jacques
Published in Molecular aspects of medicine (01.02.2016)
Published in Molecular aspects of medicine (01.02.2016)
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Journal Article
Lactate and Acidity in the Cancer Microenvironment
Parks, Scott K, Mueller-Klieser, Wolfgang, Pouysségur, Jacques
Published in Annual review of cancer biology (09.03.2020)
Published in Annual review of cancer biology (09.03.2020)
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Journal Article
Disrupting proton dynamics and energy metabolism for cancer therapy
Parks, Scott K., Chiche, Johanna, Pouysségur, Jacques
Published in Nature reviews. Cancer (01.09.2013)
Published in Nature reviews. Cancer (01.09.2013)
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Journal Article
Disrupting the ‘Warburg effect’ re-routes cancer cells to OXPHOS offering a vulnerability point via ‘ferroptosis’-induced cell death
Ždralević, Maša, Vučetić, Milica, Daher, Boutaina, Marchiq, Ibtissam, Parks, Scott K., Pouysségur, Jacques
Published in Advances in biological regulation (01.05.2018)
Published in Advances in biological regulation (01.05.2018)
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Journal Article
Hypoxia promotes tumor cell survival in acidic conditions by preserving ATP levels
Parks, Scott K., Mazure, Nathalie M., Counillon, Laurent, Pouysségur, Jacques
Published in Journal of cellular physiology (01.09.2013)
Published in Journal of cellular physiology (01.09.2013)
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Journal Article
AKT1 restricts the invasive capacity of head and neck carcinoma cells harboring a constitutively active PI3 kinase activity
Brolih, Sanja, Parks, Scott K, Vial, Valérie, Durivault, Jérôme, Mostosi, Livio, Pouysségur, Jacques, Pagès, Gilles, Picco, Vincent
Published in BMC cancer (05.03.2018)
Published in BMC cancer (05.03.2018)
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Journal Article