A comparative analysis of algorithms for somatic SNV detection in cancer
Roberts, Nicola D, Kortschak, R Daniel, Parker, Wendy T, Schreiber, Andreas W, Branford, Susan, Scott, Hamish S, Glonek, Garique, Adelson, David L
Published in Bioinformatics (15.09.2013)
Published in Bioinformatics (15.09.2013)
Get full text
Journal Article
Sensitive Detection of BCR-ABL1 Mutations in Patients With Chronic Myeloid Leukemia After Imatinib Resistance Is Predictive of Outcome During Subsequent Therapy
PARKER, Wendy T, LAWRENCE, Rebecca M, HO, Musei, IRWIN, Darryl L, SCOTT, Hamish S, HUGHES, Timothy P, BRANFORD, Susan
Published in Journal of clinical oncology (10.11.2011)
Published in Journal of clinical oncology (10.11.2011)
Get full text
Journal Article
Tyrosine kinase inhibitor resistance in chronic myeloid leukemia cell lines: investigating resistance pathways
Tang, Carine, Schafranek, Lisa, Watkins, Dale B., Parker, Wendy T., Moore, Sarah, Prime, Jodi A., White, Deborah L., Hughes, Timothy P.
Published in Leukemia & lymphoma (01.11.2011)
Published in Leukemia & lymphoma (01.11.2011)
Get full text
Journal Article
ASXL1 and BIM germ line variants predict response and identify CML patients with the greatest risk of imatinib failure
Marum, Justine E., Yeung, David T., Purins, Leanne, Reynolds, John, Parker, Wendy T., Stangl, Doris, Wang, Paul P.S., Price, David J., Tuke, Jonathan, Schreiber, Andreas W., Scott, Hamish S., Hughes, Timothy P., Branford, Susan
Published in Blood advances (08.08.2017)
Published in Blood advances (08.08.2017)
Get full text
Journal Article
Integrative genomic analysis reveals cancer-associated mutations at diagnosis of CML in patients with high-risk disease
Branford, Susan, Wang, Paul, Yeung, David T., Thomson, Daniel, Purins, Adrian, Wadham, Carol, Shahrin, Nur Hezrin, Marum, Justine E., Nataren, Nathalie, Parker, Wendy T., Geoghegan, Joel, Feng, Jinghua, Shanmuganathan, Naranie, Mueller, Martin C., Dietz, Christian, Stangl, Doris, Donaldson, Zoe, Altamura, Haley, Georgievski, Jasmina, Braley, Jodi, Brown, Anna, Hahn, Christopher, Walker, Ieuan, Kim, Soo-Hyun, Choi, Soo-Young, Park, Sa-Hee, Kim, Dong-Wook, White, Deborah L., Yong, Agnes S.M., Ross, David M., Scott, Hamish S., Schreiber, Andreas W., Hughes, Timothy P.
Published in Blood (30.08.2018)
Published in Blood (30.08.2018)
Get full text
Journal Article
Prognosis for patients with CML and >10% BCR-ABL1 after 3 months of imatinib depends on the rate of BCR-ABL1 decline
Branford, Susan, Yeung, David T., Parker, Wendy T., Roberts, Nicola D., Purins, Leanne, Braley, Jodi A., Altamura, Haley K., Yeoman, Alexandra L., Georgievski, Jasmina, Jamison, Bronte A., Phillis, Stuart, Donaldson, Zoe, Leong, Mary, Fletcher, Linda, Seymour, John F., Grigg, Andrew P., Ross, David M., Hughes, Timothy P.
Published in Blood (24.07.2014)
Published in Blood (24.07.2014)
Get full text
Journal Article
BAM-matcher: a tool for rapid NGS sample matching
Wang, Paul P S, Parker, Wendy T, Branford, Susan, Schreiber, Andreas W
Published in Bioinformatics (Oxford, England) (01.09.2016)
Published in Bioinformatics (Oxford, England) (01.09.2016)
Get full text
Journal Article
Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer
Singhal, Deepak, Hahn, Christopher N., Feurstein, Simone, Wee, Li Yan A., Moma, Luke, Kutyna, Monika M., Chhetri, Rakchha, Eshraghi, Leila, Schreiber, Andreas W., Feng, Jinghua, Wang, Paul P-S., Babic, Milena, Parker, Wendy T., Gao, Song, Moore, Sarah, Das, Soma, Thomas, David, Pattnaik, Swetansu, Brown, Anna L., D’Andrea, Richard J., Poplawski, Nicola K., Thomas, Daniel, Scott, Hamish S., Godley, Lucy A., Hiwase, Devendra K.
Published in Leukemia (01.11.2021)
Published in Leukemia (01.11.2021)
Get full text
Journal Article
The impact of multiple low-level BCR-ABL1 mutations on response to ponatinib
Parker, Wendy T., Yeung, David T.O., Yeoman, Alexandra L., Altamura, Haley K., Jamison, Bronte A., Field, Chani R., Hodgson, J. Graeme, Lustgarten, Stephanie, Rivera, Victor M., Hughes, Timothy P., Branford, Susan
Published in Blood (14.04.2016)
Published in Blood (14.04.2016)
Get full text
Journal Article
Compound mutations in BCR-ABL1 are not major drivers of primary or secondary resistance to ponatinib in CP-CML patients
Deininger, Michael W., Hodgson, J. Graeme, Shah, Neil P., Cortes, Jorge E., Kim, Dong-Wook, Nicolini, Franck E., Talpaz, Moshe, Baccarani, Michele, Müller, Martin C., Li, Jin, Parker, Wendy T., Lustgarten, Stephanie, Clackson, Tim, Haluska, Frank G., Guilhot, Francois, Kantarjian, Hagop M., Soverini, Simona, Hochhaus, Andreas, Hughes, Timothy P., Rivera, Victor M., Branford, Susan
Published in Blood (11.02.2016)
Published in Blood (11.02.2016)
Get full text
Journal Article
The mutational burden of therapy-related myeloid neoplasms is similar to primary myelodysplastic syndrome but has a distinctive distribution
Singhal, Deepak, Wee, Li Yan A., Kutyna, Monika M., Chhetri, Rakchha, Geoghegan, Joel, Schreiber, Andreas W., Feng, Jinghua, Wang, Paul P.-S., Babic, Milena, Parker, Wendy T., Hiwase, Smita, Edwards, Suzanne, Moore, Sarah, Branford, Susan, Kuzmanovic, Teodora, Singhal, Nimit, Gowda, Raghu, Brown, Anna L., Arts, Peer, To, Luen B., Bardy, Peter G., Lewis, Ian D., D’Andrea, Richard J., Maciejewski, Jaroslaw P., Scott, Hamish S., Hahn, Christopher N., Hiwase, Devendra K.
Published in Leukemia (01.12.2019)
Published in Leukemia (01.12.2019)
Get full text
Journal Article
Germ line ERG haploinsufficiency defines a new syndrome with cytopenia and hematological malignancy predisposition
Zerella, Jiarna R., Homan, Claire C., Arts, Peer, Lin, Xuzhu, Spinelli, Sam J., Venugopal, Parvathy, Babic, Milena, Brautigan, Peter J., Truong, Lynda, Arriola-Martinez, Luis, Moore, Sarah, Hollins, Rachel, Parker, Wendy T., Nguyen, Hung, Kassahn, Karin S., Branford, Susan, Feurstein, Simone, Larcher, Lise, Sicre de Fontbrune, Flore, Demirdas, Serwet, de Munnik, Sonja, Antoine-Poirel, Hélène, Brichard, Benedicte, Mansour, Sahar, Gordon, Kristiana, Baliakas, Panagiotis, Blombery, Piers, Fox, Lucy C., Donadieu, Jean, Rio-Machin, Ana, Steinberg-Shemer, Orna, Morgan, Neil V., Ngeow, Joanne Y. Y., Skokowa, Julia, Pinese, Mark, Cowley, Mark J., Wlodarski, Marcin W., Koppayi, Ashwin, Dobbins, Sara, Mutsaers, Pim G. N. J., Nichols, Kim E., Oak, Ninad, DeMille, Desiree, Mao, Rong, Crawford, Ali, McCarrier, Julie, Basel, Donald, Flores-Daboub, Josue, Drazer, Michael W., Phillips, Kerry, Poplawski, Nicola K., Birdsey, Graeme M., Pirri, Daniela, Ostergaard, Pia, Simons, Annet, Godley, Lucy A., Ross, David M., Hiwase, Devendra K., Soulier, Jean, Brown, Anna L., Carmichael, Catherine L., Scott, Hamish S., Hahn, Christopher N.
Published in Blood (24.10.2024)
Published in Blood (24.10.2024)
Get full text
Journal Article
Poor response to second-line kinase inhibitors in chronic myeloid leukemia patients with multiple low-level mutations, irrespective of their resistance profile
Parker, Wendy T., Ho, Musei, Scott, Hamish S., Hughes, Timothy P., Branford, Susan
Published in Blood (08.03.2012)
Published in Blood (08.03.2012)
Get full text
Journal Article
Many BCR-ABL1 compound mutations reported in chronic myeloid leukemia patients may actually be artifacts due to PCR-mediated recombination
Parker, Wendy T., Phillis, Stuart R., Yeung, David T.O., Hughes, Timothy P., Scott, Hamish S., Branford, Susan
Published in Blood (03.07.2014)
Published in Blood (03.07.2014)
Get full text
Journal Article
Novel modes of MPL activation in triple-negative myeloproliferative neoplasms
Samaraweera, Saumya E., Geukens, Tatjana, Casolari, Debora A., Nguyen, Tran, Sun, Caitlyn, Bailey, Sheree, Moore, Sarah, Feng, Jinghua, Schreiber, Andreas W., Parker, Wendy T., Brown, Anna L., Butcher, Carolyn, Bardy, Peter G., Osborn, Michael, Scott, Hamish S., Talaulikar, Dipti, Grove, Carolyn S., Hahn, Christopher N., D'Andrea, Richard J., Ross, David M.
Published in Pathology (01.02.2023)
Published in Pathology (01.02.2023)
Get full text
Journal Article
An RNA-Based Next Generation Sequencing (NGS) Strategy Detects More Cancer Gene Mutations Than a DNA-Based Approach for the Prediction and Assessment of Resistance in CML
Branford, Susan, Wadham, Carol, Shanmuganathan, Naranie, Thomson, Daniel, Shahrin, NUR Hezrin, Feng, Jinghua, Saunders, Verity A, Parker, Wendy T, King, Rob, Wang, Paul, Scott, Hamish S, Schreiber, Andreas, Hughes, Timothy P.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
Get full text
Journal Article
Deleterious Germline Variants, Especially in the DNA Repair Pathway, Are Common in Patients with Non-Related Multiple Cancers, One of Them Being Hematological Malignancy
Singhal, Deepak, Hahn, Christopher N, Moma, Luke D, Wee, Li Yan A, Chhetri, Rakchha, Babic, Milena, Kutyna, Monika M, Hiwase, Smita, Parker, Wendy T, Feng, Jinghua, Schreiber, Andreas W, Geoghegan, Joel, Arts, Peer, Gowda, Raghu, Singhal, Nimit, Brown, Anna L, D'Andrea, Richard J, Lewis, Ian D, Scott, Hamish S, Godley, Lucy A, Hiwase, Devendra K
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
Get full text
Journal Article
The Adverse Effect of High Sokal Risk for First Line Imatinib Treated Patients Is Overcome By a Rapid Rate of BCR-ABL Decline Measured As Early As 1 Month of Treatment
Branford, Susan, Yeung, David T, Ross, David M, Parker, Wendy T, Braley, Jodi, Seymour, John F, Hughes, Timothy P.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
Get full text
Journal Article
Any BCR-ABL Reduction Below 10% At 6 Months Of Therapy Significantly Improves Outcome For CML Patients With a Poor Response At 3 Months
Branford, Susan, Roberts, Nicola, Yeung, David T, Altamura, Haley, Parker, Wendy T, Hughes, Timothy P.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
Get full text
Journal Article