Search Results - "Parker, Michael H" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Macrocyclic BACE inhibitors: Optimization of a micromolar hit to nanomolar leads

Macrocyclic BACE inhibitors: Optimization of a micromolar hit to nanomolar leads

by Huang, Yifang, Strobel, Eric D., Ho, Chih Y., Reynolds, Charles H., Conway, Kelly A., Piesvaux, Jennifer A., Brenneman, Douglas E., Yohrling, George J., Moore Arnold, H., Rosenthal, Daniel, Alexander, Richard S., Tounge, Brett A., Mercken, Marc, Vandermeeren, Marc, Parker, Michael H., Reitz, Allen B., Baxter, Ellen W.
Published in Bioorganic & medicinal chemistry letters (15.05.2010)

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A novel technique using long segment patch angioplasty maturation to increase the maturation rate of arteriovenous fistulas

A novel technique using long segment patch angioplasty maturation to increase the maturation rate of arteriovenous fistulas

by Parker, Michael H., Hashemi, Homayoun, Grant, Courtney, Colpitts, Dayle K., Kfoury, Elias, Mukherjee, Dipankar, Neville, Richard
Published in Journal of vascular surgery (01.07.2021)

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Antimalarial, Antiproliferative, and Antitumor Activities of Artemisinin-Derived, Chemically Robust, Trioxane Dimers

Antimalarial, Antiproliferative, and Antitumor Activities of Artemisinin-Derived, Chemically Robust, Trioxane Dimers

by Posner, Gary H, Ploypradith, Poonsakdi, Parker, Michael H, O'Dowd, Hardwin, Woo, Soon-Hyung, Northrop, John, Krasavin, Mikhail, Dolan, Patrick, Kensler, Thomas W, Xie, Suji, Shapiro, Theresa A
Published in Journal of medicinal chemistry (21.10.1999)

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Chest Tube Management Practices by Trauma Surgeons

Chest Tube Management Practices by Trauma Surgeons

by Parker, Michael H., Newcomb, Anna B., Liu, Chang, Michetti, Christopher P.
Published in The Journal of surgical research (01.12.2019)

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Potency of a small molecule that targets the molluscum contagiosum virus processivity factor increases when conjugated to a tripeptide

Potency of a small molecule that targets the molluscum contagiosum virus processivity factor increases when conjugated to a tripeptide

by Guan, Hancheng, Nuth, Manunya, Scott, Richard W., Parker, Michael H., Strobel, Eric D., Reitz, Allen B., Kulp, John L., Ricciardi, Robert P.
Published in Antiviral research (01.06.2024)

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A small molecule that targets the processivity factor of molluscum contagiosum virus has therapeutic potential

A small molecule that targets the processivity factor of molluscum contagiosum virus has therapeutic potential

by Guan, Hancheng, Nuth, Manunya, Isaacs, Stuart N., Xiao, Yuhong, Scott, Richard W., Parker, Michael H., Strobel, Eric D., Kulp, John L., Bailey, Thomas R., Reitz, Allen B., Ricciardi, Robert P.
Published in Antiviral research (01.03.2023)

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Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy

Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy

by Lu, Tianbao, Schubert, Carsten, Cummings, Maxwell D., Bignan, Gilles, Connolly, Peter J., Smans, Karine, Ludovici, Donald, Parker, Michael H., Meyer, Christophe, Rocaboy, Christian, Alexander, Richard, Grasberger, Bruce, De Breucker, Sabine, Esser, Norbert, Fraiponts, Erwin, Gilissen, Ron, Janssens, Boudewijn, Peeters, Danielle, Van Nuffel, Luc, Vermeulen, Peter, Bischoff, James, Meerpoel, Lieven
Published in Bioorganic & medicinal chemistry letters (01.07.2018)

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Carotid-Axillary Bypass as an Alternative to Carotid-Subclavian Bypass Following Coverage of Left Subclavian Artery During TEVAR

Carotid-Axillary Bypass as an Alternative to Carotid-Subclavian Bypass Following Coverage of Left Subclavian Artery During TEVAR

by Parker, Michael H, Colpitts, Dayle K, Gilson, Genevieve F, Ryan, Liam, Mukherjee, Dipankar
Published in Vascular and endovascular surgery (01.04.2021)

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Mutation and structure guided discovery of an antiviral small molecule that mimics an essential C-Terminal tripeptide of the vaccinia D4 processivity factor

Mutation and structure guided discovery of an antiviral small molecule that mimics an essential C-Terminal tripeptide of the vaccinia D4 processivity factor

by Nuth, Manunya, Guan, Hancheng, Xiao, Yuhong, Kulp, John L., Parker, Michael H., Strobel, Eric D., Isaacs, Stuart N., Scott, Richard W., Reitz, Allen B., Ricciardi, Robert P.
Published in Antiviral research (01.02.2019)

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Herpes Simplex Virus-1 infection in human primary corneal epithelial cells is blocked by a stapled peptide that targets processive DNA synthesis

Herpes Simplex Virus-1 infection in human primary corneal epithelial cells is blocked by a stapled peptide that targets processive DNA synthesis

by Guan, Hancheng, Nuth, Manunya, Lee, Vivian, Lin, Chenyan, Mitchell, Claire H., Lu, Wennan, Scott, Richard W., Parker, Michael H., Kulp, John L., Reitz, Allen B., Ricciardi, Robert P.
Published in The ocular surface (01.01.2021)

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The role of sulfamide derivatives in medicinal chemistry: a patent review (2006-2008)

The role of sulfamide derivatives in medicinal chemistry: a patent review (2006-2008)

by Reitz, Allen B, Smith, Garry R, Parker, Michael H
Published in Expert opinion on therapeutic patents (01.10.2009)

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Designing a diverse high-quality library for crystallography-based FBDD screening

Designing a diverse high-quality library for crystallography-based FBDD screening

by Tounge, Brett A, Parker, Michael H
Published in Methods in enzymology (2011)

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2-Amino-3,4-dihydroquinazolines as Inhibitors of BACE-1 (β-Site APP Cleaving Enzyme): Use of Structure Based Design to Convert a Micromolar Hit into a Nanomolar Lead

2-Amino-3,4-dihydroquinazolines as Inhibitors of BACE-1 (β-Site APP Cleaving Enzyme): Use of Structure Based Design to Convert a Micromolar Hit into a Nanomolar Lead

by Baxter, Ellen W, Conway, Kelly A, Kennis, Ludo, Bischoff, François, Mercken, Marc H, De Winter, Hans L, Reynolds, Charles H, Tounge, Brett A, Luo, Chi, Scott, Malcolm K, Huang, Yifang, Braeken, Mirielle, Pieters, Serge M. A, Berthelot, Didier J. C, Masure, Stefan, Bruinzeel, Wouter D, Jordan, Alfonzo D, Parker, Michael H, Boyd, Robert E, Qu, Junya, Alexander, Richard S, Brenneman, Douglas E, Reitz, Allen B
Published in Journal of medicinal chemistry (06.09.2007)

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Novel, Broad-Spectrum Anticonvulsants Containing a Sulfamide Group: Pharmacological Properties of (S)‑N‑[(6-Chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112)

Novel, Broad-Spectrum Anticonvulsants Containing a Sulfamide Group: Pharmacological Properties of (S)‑N‑[(6-Chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112)

by McComsey, David F, Smith-Swintosky, Virginia L, Parker, Michael H, Brenneman, Douglas E, Malatynska, Ewa, White, H. Steve, Klein, Brian D, Wilcox, Karen S, Milewski, Michael E, Herb, Mark, Finley, Michael F. A, Liu, Yi, Lubin, Mary Lou, Qin, Ning, Reitz, Allen B, Maryanoff, Bruce E
Published in Journal of medicinal chemistry (27.11.2013)

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Novel, Broad-Spectrum Anticonvulsants Containing a Sulfamide Group: Advancement of N-((Benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into Human Clinical Studies

Novel, Broad-Spectrum Anticonvulsants Containing a Sulfamide Group: Advancement of N-((Benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into Human Clinical Studies

by Parker, Michael H, Smith-Swintosky, Virginia L, McComsey, David F, Huang, Yifang, Brenneman, Douglas, Klein, Brian, Malatynska, Ewa, White, H. Steve, Milewski, Michael E, Herb, Mark, Finley, Michael F. A, Liu, Yi, Lubin, Mary Lou, Qin, Ning, Iannucci, Robert, Leclercq, Laurent, Cuyckens, Filip, Reitz, Allen B, Maryanoff, Bruce E
Published in Journal of medicinal chemistry (10.12.2009)

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Antimalarial Simplified 3-Aryltrioxanes: Synthesis and Preclinical Efficacy/Toxicity Testing in Rodents

Antimalarial Simplified 3-Aryltrioxanes: Synthesis and Preclinical Efficacy/Toxicity Testing in Rodents

by Posner, Gary H, Jeon, Heung Bae, Parker, Michael H, Krasavin, Mikhail, Paik, Ik-Hyeon, Shapiro, Theresa A
Published in Journal of medicinal chemistry (13.09.2001)

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Orally Active, Hydrolytically Stable, Semisynthetic, Antimalarial Trioxanes in the Artemisinin Family

Orally Active, Hydrolytically Stable, Semisynthetic, Antimalarial Trioxanes in the Artemisinin Family

by Posner, Gary H, Parker, Michael H, Northrop, John, Elias, Jeffrey S, Ploypradith, Poonsakdi, Xie, Suji, Shapiro, Theresa A
Published in Journal of medicinal chemistry (28.01.1999)

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Synthesis of (-)-5,8-dihydroxy-3R-methyl-2R-(dipropylamino)-1,2,3,4-tetrahydronaphthalene: An inhibitor of β-Amyloid1-42 aggregation

Synthesis of (-)-5,8-dihydroxy-3R-methyl-2R-(dipropylamino)-1,2,3,4-tetrahydronaphthalene: An inhibitor of β-Amyloid1-42 aggregation

by PARKER, Michael H, CHEN, Robert, CONWAY, Kelly A, LEE, Daniel H. S, CHI LUO, BOYD, Robert E, NORTEY, Samuel O, ROSS, Tina M, SCOTT, Malcolm K, REITZ, Allen B
Published in Bioorganic & medicinal chemistry (01.11.2002)

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Long-term Outcomes of Patch Angioplasty Maturation for Arteriovenous Fistulas

Long-term Outcomes of Patch Angioplasty Maturation for Arteriovenous Fistulas

by Parker, Michael H., Hashemi, Homayoun, Bachmann, Caila, Ramsey, Lolita, Mukherjee, Dipankar, Neville, Richard
Published in Journal of vascular surgery (01.06.2023)

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Management of Large-Bore Access Complications in the Era of Transcatheter Aortic Valve Replacement

Management of Large-Bore Access Complications in the Era of Transcatheter Aortic Valve Replacement

by Parker, Michael H., Ryan, Liam P., Mukherjee, Dipankar
Published in Journal of vascular surgery (01.08.2019)

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