Pleiotropic Effects of mTOR and Autophagy During Development and Aging
Schmeisser, Kathrin, Parker, J. Alex
Published in Frontiers in cell and developmental biology (11.09.2019)
Published in Frontiers in cell and developmental biology (11.09.2019)
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Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans
Therrien, Martine, Rouleau, Guy A, Dion, Patrick A, Parker, J Alex
Published in PloS one (12.12.2013)
Published in PloS one (12.12.2013)
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G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA
Aulas, Anaïs, Caron, Guillaume, Gkogkas, Christos G, Mohamed, Nguyen-Vi, Destroismaisons, Laurie, Sonenberg, Nahum, Leclerc, Nicole, Parker, J Alex, Vande Velde, Christine
Published in The Journal of cell biology (13.04.2015)
Published in The Journal of cell biology (13.04.2015)
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Phosphoglycolate phosphatase homologs act as glycerol-3-phosphate phosphatase to control stress and healthspan in C. elegans
Possik, Elite, Schmitt, Clémence, Al-Mass, Anfal, Bai, Ying, Côté, Laurence, Morin, Johanne, Erb, Heidi, Oppong, Abel, Kahloan, Wahab, Parker, J. Alex, Madiraju, S. R. Murthy, Prentki, Marc
Published in Nature communications (11.01.2022)
Published in Nature communications (11.01.2022)
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AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease
Vázquez-Manrique, Rafael P, Farina, Francesca, Cambon, Karine, Dolores Sequedo, María, Parker, Alex J, Millán, José María, Weiss, Andreas, Déglon, Nicole, Neri, Christian
Published in Human molecular genetics (15.03.2016)
Published in Human molecular genetics (15.03.2016)
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Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo
Vaccaro, Alexandra, Patten, Shunmoogum A, Aggad, Dina, Julien, Carl, Maios, Claudia, Kabashi, Edor, Drapeau, Pierre, Parker, J. Alex
Published in Neurobiology of disease (01.07.2013)
Published in Neurobiology of disease (01.07.2013)
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Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans
Vaccaro, Alexandra, Tauffenberger, Arnaud, Aggad, Dina, Rouleau, Guy, Drapeau, Pierre, Parker, J Alex
Published in PloS one (21.02.2012)
Published in PloS one (21.02.2012)
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The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis
Bose, Poulomee, Tremblay, Elsa, Maios, Claudia, Narasimhan, Vijay, Armstrong, Gary A. B., Liao, Meijiang, Parker, J. Alex, Robitaille, Richard, Wen, Xiao Yan, Barden, Christopher, Drapeau, Pierre
Published in Neurotherapeutics (01.10.2019)
Published in Neurotherapeutics (01.10.2019)
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Fatty acids derived from the probiotic Lacticaseibacillus rhamnosus HA-114 suppress age-dependent neurodegeneration
Labarre, Audrey, Guitard, Ericka, Tossing, Gilles, Forest, Anik, Bareke, Eric, Labrecque, Marjorie, Tétreault, Martine, Ruiz, Matthieu, Alex Parker, J.
Published in Communications biology (07.12.2022)
Published in Communications biology (07.12.2022)
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Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio
Vaccaro, Alexandra, Patten, Shunmoogum A, Ciura, Sorana, Maios, Claudia, Therrien, Martine, Drapeau, Pierre, Kabashi, Edor, Parker, J Alex
Published in PloS one (27.07.2012)
Published in PloS one (27.07.2012)
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The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease
Farina, Francesca, Lambert, Emmanuel, Commeau, Lucie, Lejeune, François-Xavier, Roudier, Nathalie, Fonte, Cosima, Parker, J. Alex, Boddaert, Jacques, Verny, Marc, Baulieu, Etienne-Emile, Neri, Christian
Published in Scientific reports (21.06.2017)
Published in Scientific reports (21.06.2017)
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Modulating the endoplasmic reticulum stress response attenuates neurodegeneration in a Caenorhabditis elegans model of spinal muscular atrophy
Doyle, James J, Vrancx, Celine, Maios, Claudia, Labarre, Audrey, Patten, Shunmoogum A, Parker, J Alex
Published in Disease models & mechanisms (22.12.2020)
Published in Disease models & mechanisms (22.12.2020)
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Tau hyperphosphorylation and deregulation of calcineurin in mouse models of Huntington's disease
Gratuze, Maud, Noël, Anastasia, Julien, Carl, Cisbani, Giulia, Milot-Rousseau, Philippe, Morin, Françoise, Dickler, Maya, Goupil, Claudia, Bezeau, François, Poitras, Isabelle, Bissonnette, Stéphanie, Whittington, Robert A, Hébert, Sébastien S, Cicchetti, Francesca, Parker, J Alex, Samadi, Pershia, Planel, Emmanuel
Published in Human molecular genetics (01.01.2015)
Published in Human molecular genetics (01.01.2015)
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Restless legs syndrome-associated MEIS1 risk variant influences iron homeostasis
Catoire, Hélène, Dion, Patrick A., Xiong, Lan, Amari, Mourabit, Gaudet, Rebecca, Girard, Simon L., Noreau, Anne, Gaspar, Claudia, Turecki, Gustavo, Montplaisir, Jacques Y., Parker, J. Alex, Rouleau, Guy A.
Published in Annals of neurology (01.07.2011)
Published in Annals of neurology (01.07.2011)
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