Cysteine specific targeting of the functionally distinct peroxiredoxin and glutaredoxin proteins by the investigational disulfide BNP7787
Parker, Aulma R, Petluru, Pavankumar N, Nienaber, Vicki L, Badger, John, Leverett, Betsy D, Jair, Kamwing, Sridhar, Vandana, Logan, Cheyenne, Ayala, Philippe Y, Kochat, Harry, Hausheer, Frederick H
Published in Molecules (Basel, Switzerland) (18.03.2015)
Published in Molecules (Basel, Switzerland) (18.03.2015)
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Journal Article
Analysis of BNP7787 thiol-disulfide exchange reactions in phosphate buffer and human plasma using microscale electrochemical high performance liquid chromatography
Shanmugarajah, Dakshine, Ding, Daoyuan, Huang, Quili, Chen, Xinghai, Kochat, Harry, Petluru, Pavankumar N., Ayala, Philippe Y., Parker, Aulma R., Hausheer, Frederick H.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.04.2009)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.04.2009)
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Journal Article
BNP7787-mediated modulation of paclitaxel- and cisplatin-induced aberrant microtubule protein polymerization in vitro
Parker, Aulma R, Petluru, Pavankumar N, Wu, Meizhen, Zhao, Min, Kochat, Harry, Hausheer, Frederick H
Published in Molecular cancer therapeutics (01.09.2010)
Published in Molecular cancer therapeutics (01.09.2010)
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Journal Article
Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of gamma-glutamyl transpeptidase
Hausheer, Frederick H, Shanmugarajah, Dakshine, Leverett, Betsy D, Chen, Xinghai, Huang, Quili, Kochat, Harry, Petluru, Pavankumar N, Parker, Aulma R
Published in Cancer chemotherapy and pharmacology (01.04.2010)
Published in Cancer chemotherapy and pharmacology (01.04.2010)
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Journal Article
Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787
Parker, Aulma R, Petluru, Pavankumar N, Nienaber, Vicki L, Zhao, Min, Ayala, Philippe Y, Badger, John, Chie-Leon, Barbara, Sridhar, Vandana, Logan, Cheyenne, Kochat, Harry, Hausheer, Frederick H
Published in OncoTargets and therapy (01.01.2015)
Published in OncoTargets and therapy (01.01.2015)
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Journal Article
New approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agent
HAUSHEER, Frederick H, KOCHAT, Harry, PARKER, Aulma R, DAOYUAN DING, SHIJE YAO, HAMILTON, Susan E, PETLURU, Pavankumar N, LEVERETT, Betsy D, BAIN, Stacey H, SAXE, Jeffrey D
Published in Cancer chemotherapy and pharmacology (01.07.2003)
Published in Cancer chemotherapy and pharmacology (01.07.2003)
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Conference Proceeding
Journal Article
Escherichia coli imidazoleglycerol phosphate dehydratase: spectroscopic characterization of the enzymic product and the steric course of the reaction
Parker, Aulma R, Moore, Jeffrey A, Schwab, John M, Davisson, V. Jo
Published in Journal of the American Chemical Society (01.11.1995)
Published in Journal of the American Chemical Society (01.11.1995)
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Journal Article