Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models
Sardi, S. Pablo, Viel, Catherine, Clarke, Jennifer, Treleaven, Christopher M., Richards, Amy M., Park, Hyejung, Olszewski, Maureen A., Dodge, James C., Marshall, John, Makino, Elina, Wang, Bing, Sidman, Richard L., Cheng, Seng H., Shihabuddin, Lamya S.
Published in Proceedings of the National Academy of Sciences - PNAS (07.03.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (07.03.2017)
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CNS-accessible Inhibitor of Glucosylceramide Synthase for Substrate Reduction Therapy of Neuronopathic Gaucher Disease
Marshall, John, Sun, Ying, Bangari, Dinesh S, Budman, Eva, Park, Hyejung, Nietupski, Jennifer B, Allaire, Amy, Cromwell, Mary A, Wang, Bing, Grabowski, Gregory A, Leonard, John P, Cheng, Seng H
Published in Molecular therapy (01.06.2016)
Published in Molecular therapy (01.06.2016)
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Substrate reduction therapy using Genz‐667161 reduces levels of pathogenic components in a mouse model of neuronopathic forms of Gaucher disease
Blumenreich, Shani, Yaacobi, Chen, Vardi, Ayelet, Barav, Or B., Vitner, Einat B., Park, Hyejung, Wang, Bing, Cheng, Seng H., Sardi, Sergio P., Futerman, Anthony H.
Published in Journal of neurochemistry (01.03.2021)
Published in Journal of neurochemistry (01.03.2021)
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Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers[S]
Shaner, Rebecca L., Allegood, Jeremy C., Park, Hyejung, Wang, Elaine, Kelly, Samuel, Haynes, Christopher A., Sullards, M. Cameron, Merrill, Alfred H.
Published in Journal of lipid research (01.08.2009)
Published in Journal of lipid research (01.08.2009)
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Sphingolipidomics: Methods for the comprehensive analysis of sphingolipids
Haynes, Christopher A., Allegood, Jeremy C., Park, Hyejung, Sullards, M. Cameron
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.09.2009)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.09.2009)
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Glucosylceramide synthase inhibition protects against cardiac hypertrophy in chronic kidney disease
Baccam, Gabriel C., Xie, Jian, Jin, Xin, Park, Hyejung, Wang, Bing, Husson, Hervé, Ibraghimov-Beskrovnaya, Oxana, Huang, Chou-Long
Published in Scientific reports (04.06.2022)
Published in Scientific reports (04.06.2022)
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Preclinical pharmacology of glucosylceramide synthase inhibitor venglustat in a GBA-related synucleinopathy model
Viel, Catherine, Clarke, Jennifer, Kayatekin, Can, Richards, Amy M., Chiang, Ming Sum R., Park, Hyejung, Wang, Bing, Shihabuddin, Lamya S., Sardi, S. Pablo
Published in Scientific reports (22.10.2021)
Published in Scientific reports (22.10.2021)
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Human iPSC-derived astrocytes generated from donors with globoid cell leukodystrophy display phenotypes associated with disease
Lieberman, Richard, Cortes, Leslie K, Gao, Grace, Park, Hyejung, Wang, Bing, Jones, Patrick L, Hunter, R. Bridge, Leonard, John P, Barker, Robert H
Published in PloS one (03.08.2022)
Published in PloS one (03.08.2022)
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A novel brain-penetrant oral UGT8 inhibitor decreases in vivo galactosphingolipid biosynthesis in murine Krabbe disease
Zaccariotto, Eva, Cachón-González, María Begoña, Wang, Bing, Lim, Sungtaek, Hirth, Bradford, Park, Hyejung, Fezoui, Malika, Sardi, S.Pablo, Mason, Paul, Barker, Robert H., Cox, Timothy M.
Published in Biomedicine & pharmacotherapy (01.05.2022)
Published in Biomedicine & pharmacotherapy (01.05.2022)
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Lipid Sorting by Ceramide Structure from Plasma Membrane to ER for the Cholera Toxin Receptor Ganglioside GM1
Chinnapen, Daniel J.-F., Hsieh, Wan-Ting, te Welscher, Yvonne M., Saslowsky, David E., Kaoutzani, Lydia, Brandsma, Eelke, D'Auria, Ludovic, Park, Hyejung, Wagner, Jessica S., Drake, Kimberly R., Kang, Minchul, Benjamin, Thomas, Ullman, M. David, Costello, Catherine E., Kenworthy, Anne K., Baumgart, Tobias, Massol, Ramiro H., Lencer, Wayne I.
Published in Developmental cell (11.09.2012)
Published in Developmental cell (11.09.2012)
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Association between the presence of delirium during intensive care unit admission and cognitive impairment or psychiatric problems: the Korean ICU National Data Study
Ko, Ryoung-Eun, Kang, Danbee, Park, Hyejung, Cho, Juhee, Suh, Gee Young, Chung, Chi Ryang
Published in Journal of intensive care (14.02.2022)
Published in Journal of intensive care (14.02.2022)
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Sphingosine 1-Phosphate (S1P) Lyase Deficiency Increases Sphingolipid Formation via Recycling at the Expense of de Novo Biosynthesis in Neurons
Hagen-Euteneuer, Nadine, Lütjohann, Dieter, Park, Hyejung, Merrill, Alfred H., van Echten-Deckert, Gerhild
Published in The Journal of biological chemistry (16.03.2012)
Published in The Journal of biological chemistry (16.03.2012)
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Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease
Merrill, Alfred H., Stokes, Todd H., Momin, Amin, Park, Hyejung, Portz, Brent J., Kelly, Samuel, Wang, Elaine, Sullards, M. Cameron, Wang, May Dongmei
Published in Journal of lipid research (01.04.2009)
Published in Journal of lipid research (01.04.2009)
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Subcellular Origin of Sphingosine 1-Phosphate Is Essential for Its Toxic Effect in Lyase-deficient Neurons
Hagen, Nadine, Van Veldhoven, Paul P., Proia, Richard L., Park, Hyejung, Merrill, Alfred H., van Echten-Deckert, Gerhild
Published in The Journal of biological chemistry (24.04.2009)
Published in The Journal of biological chemistry (24.04.2009)
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Forecasting the Walking Assistance Rehabilitation Level of Stroke Patients Using Artificial Intelligence
Seo, Kanghyeon, Chung, Bokjin, Panchaseelan, Hamsa Priya, Kim, Taewoo, Park, Hyejung, Oh, Byungmo, Chun, Minho, Won, Sunjae, Kim, Donkyu, Beom, Jaewon, Jeon, Doyoung, Yang, Jihoon
Published in Diagnostics (Basel) (15.06.2021)
Published in Diagnostics (Basel) (15.06.2021)
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Glucosylceramide in cerebrospinal fluid of patients with GBA-associated and idiopathic Parkinson’s disease enrolled in PPMI
Huh, Young Eun, Park, Hyejung, Chiang, Ming Sum Ruby, Tuncali, Idil, Liu, Ganqiang, Locascio, Joseph J., Shirvan, Julia, Hutten, Samantha J., Rotunno, Melissa S., Viel, Catherine, Shihabuddin, Lamya S., Wang, Bing, Sardi, Sergio Pablo, Scherzer, Clemens R.
Published in NPJ Parkinson's Disease (22.11.2021)
Published in NPJ Parkinson's Disease (22.11.2021)
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Relationship between Use of Rehabilitation Resources and ICU Readmission and ER Visits in ICU Survivors: the Korean ICU National Data Study 2008-2015
Park, Yun Hee, Ko, Ryoung Eun, Kang, Danbee, Park, Jinkyeong, Jeon, Kyeongman, Yang, Jeong Hoon, Park, Chi Min, Cho, Joongbum, Park, Young Sook, Park, Hyejung, Cho, Juhee, Guallar, Eliseo, Suh, Gee Young, Chung, Chi Ryang
Published in Journal of Korean medical science (20.04.2020)
Published in Journal of Korean medical science (20.04.2020)
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The galactocerebrosidase enzyme contributes to the maintenance of a functional hematopoietic stem cell niche
Visigalli, Ilaria, Ungari, Silvia, Martino, Sabata, Park, Hyejung, Cesani, Martina, Gentner, Bernhard, Sergi Sergi, Lucia, Orlacchio, Aldo, Naldini, Luigi, Biffi, Alessandra
Published in Blood (16.09.2010)
Published in Blood (16.09.2010)
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Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells
Morad, Samy A. F., Messner, Maria C., Levin, Jonathan C., Abdelmageed, Noha, Park, Hyejung, Merrill, Alfred H., Cabot, Myles C.
Published in Cancer chemotherapy and pharmacology (01.03.2013)
Published in Cancer chemotherapy and pharmacology (01.03.2013)
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