HER2-enriched subtype as a predictor of pathological complete response following trastuzumab and lapatinib without chemotherapy in early-stage HER2-positive breast cancer (PAMELA): an open-label, single-group, multicentre, phase 2 trial
Llombart-Cussac, Antonio, MD, Cortés, Javier, MD, Paré, Laia, PhD, Galván, Patricia, BS, Bermejo, Begoña, MD, Martínez, Noelia, MD, Vidal, Maria, MD, Pernas, Sònia, MD, López, Rafael, MD, Muñoz, Montserrat, MD, Nuciforo, Paolo, MD, Morales, Serafín, MD, Oliveira, Mafalda, MD, de la Peña, Lorena, PhD, Peláez, Alexandra, MD, Prat, Aleix, Dr
Published in The lancet oncology (01.04.2017)
Published in The lancet oncology (01.04.2017)
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Clinical, pathological, and PAM50 gene expression features of HER2-low breast cancer
Schettini, Francesco, Chic, Nuria, Brasó-Maristany, Fara, Paré, Laia, Pascual, Tomás, Conte, Benedetta, Martínez-Sáez, Olga, Adamo, Barbara, Vidal, Maria, Barnadas, Esther, Fernández-Martinez, Aranzazu, González-Farre, Blanca, Sanfeliu, Esther, Cejalvo, Juan Miguel, Perrone, Giuseppe, Sabarese, Giovanna, Zalfa, Francesca, Peg, Vicente, Fasani, Roberta, Villagrasa, Patricia, Gavilá, Joaquín, Barrios, Carlos H., Lluch, Ana, Martín, Miguel, Locci, Mariavittoria, De Placido, Sabino, Prat, Aleix
Published in NPJ breast cancer (04.01.2021)
Published in NPJ breast cancer (04.01.2021)
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Phase 2 study of buparlisib (BKM120), a pan-class I PI3K inhibitor, in patients with metastatic triple-negative breast cancer
Garrido-Castro, Ana C, Saura, Cristina, Barroso-Sousa, Romualdo, Guo, Hao, Ciruelos, Eva, Bermejo, Begoña, Gavilá, Joaquin, Serra, Violeta, Prat, Aleix, Paré, Laia, Céliz, Pamela, Villagrasa, Patricia, Li, Yisheng, Savoie, Jennifer, Xu, Zhan, Arteaga, Carlos L, Krop, Ian E, Solit, David B, Mills, Gordon B, Cantley, Lewis C, Winer, Eric P, Lin, Nancy U, Rodon, Jordi
Published in Breast cancer research : BCR (02.11.2020)
Published in Breast cancer research : BCR (02.11.2020)
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Phenotypic changes of HER2-positive breast cancer during and after dual HER2 blockade
Brasó-Maristany, Fara, Griguolo, Gaia, Pascual, Tomás, Paré, Laia, Nuciforo, Paolo, Llombart-Cussac, Antonio, Bermejo, Begoña, Oliveira, Mafalda, Morales, Serafín, Martínez, Noelia, Vidal, Maria, Adamo, Barbara, Martínez, Olga, Pernas, Sonia, López, Rafael, Muñoz, Montserrat, Chic, Núria, Galván, Patricia, Garau, Isabel, Manso, Luis, Alarcón, Jesús, Martínez, Eduardo, Gregorio, Sara, Gomis, Roger R., Villagrasa, Patricia, Cortés, Javier, Ciruelos, Eva, Prat, Aleix
Published in Nature communications (20.01.2020)
Published in Nature communications (20.01.2020)
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Ribociclib plus letrozole versus chemotherapy for postmenopausal women with hormone receptor-positive, HER2-negative, luminal B breast cancer (CORALLEEN): an open-label, multicentre, randomised, phase 2 trial
Prat, Aleix, Saura, Cristina, Pascual, Tomás, Hernando, Cristina, Muñoz, Montserrat, Paré, Laia, González Farré, Blanca, Fernández, Pedro L, Galván, Patricia, Chic, Núria, González Farré, Xavier, Oliveira, Mafalda, Gil-Gil, Miguel, Arumi, Miriam, Ferrer, Neus, Montaño, Alvaro, Izarzugaza, Yann, Llombart-Cussac, Antonio, Bratos, Raquel, González Santiago, Santiago, Martínez, Eduardo, Hoyos, Sergio, Rojas, Beatriz, Virizuela, Juan Antonio, Ortega, Vanesa, López, Rafael, Céliz, Pamela, Ciruelos, Eva, Villagrasa, Patricia, Gavilá, Joaquín
Published in The lancet oncology (01.01.2020)
Published in The lancet oncology (01.01.2020)
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HER2-Enriched Subtype and ERBB2 Expression in HER2-Positive Breast Cancer Treated with Dual HER2 Blockade
Prat, Aleix, Pascual, Tomás, De Angelis, Carmine, Gutierrez, Carolina, Llombart-Cussac, Antonio, Wang, Tao, Cortés, Javier, Rexer, Brent, Paré, Laia, Forero, Andres, Wolff, Antonio C, Morales, Serafín, Adamo, Barbara, Brasó-Maristany, Fara, Vidal, Maria, Veeraraghavan, Jamunarani, Krop, Ian, Galván, Patricia, Pavlick, Anne C, Bermejo, Begoña, Izquierdo, Miguel, Rodrik-Outmezguine, Vanessa, Reis-Filho, Jorge S, Hilsenbeck, Susan G, Oliveira, Mafalda, Dieci, Maria Vittoria, Griguolo, Gaia, Fasani, Roberta, Nuciforo, Paolo, Parker, Joel S, Conte, PierFranco, Schiff, Rachel, Guarneri, Valentina, Osborne, C Kent, Rimawi, Mothaffar F
Published in JNCI : Journal of the National Cancer Institute (01.01.2020)
Published in JNCI : Journal of the National Cancer Institute (01.01.2020)
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Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer: final 10-year analysis of the open-label, single-arm, phase 2 APT trial
Tolaney, Sara M, Tarantino, Paolo, Graham, Noah, Tayob, Nabihah, Parè, Laia, Villacampa, Guillermo, Dang, Chau T, Yardley, Denise A, Moy, Beverly, Marcom, P Kelly, Albain, Kathy S, Rugo, Hope S, Ellis, Matthew J, Shapira, Iuliana, Wolff, Antonio C, Carey, Lisa A, Barroso-Sousa, Romualdo, Villagrasa, Patricia, DeMeo, Michelle, DiLullo, Molly, Zanudo, Jorge Gomez Tejeda, Weiss, Jakob, Wagle, Nikhil, Partridge, Ann H, Waks, Adrienne G, Hudis, Clifford A, Krop, Ian E, Burstein, Harold J, Prat, Aleix, Winer, Eric P
Published in The lancet oncology (01.03.2023)
Published in The lancet oncology (01.03.2023)
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Development and validation of the new HER2DX assay for predicting pathological response and survival outcome in early-stage HER2-positive breast cancer
Prat, Aleix, Guarneri, Valentina, Pascual, Tomás, Brasó-Maristany, Fara, Sanfeliu, Esther, Paré, Laia, Schettini, Francesco, Martínez, Débora, Jares, Pedro, Griguolo, Gaia, Dieci, Maria Vittoria, Cortés, Javier, Llombart-Cussac, Antonio, Conte, Benedetta, Marín-Aguilera, Mercedes, Chic, Nuria, Puig-Butillé, Joan Anton, Martínez, Antonio, Galván, Patricia, Tsai, Yi-Hsuan, González-Farré, Blanca, Mira, Aurea, Vivancos, Ana, Villagrasa, Patricia, Parker, Joel S., Conte, Pierfranco, Perou, Charles M.
Published in EBioMedicine (01.01.2022)
Published in EBioMedicine (01.01.2022)
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GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma
Moreno, Marta, Pedrosa, Leire, Paré, Laia, Pineda, Estela, Bejarano, Leire, Martínez, Josefina, Balasubramaniyan, Veerakumar, Ezhilarasan, Ravesanker, Kallarackal, Naveen, Kim, Sung-Hak, Wang, Jia, Audia, Alessandra, Conroy, Siobhan, Marin, Mercedes, Ribalta, Teresa, Pujol, Teresa, Herreros, Antoni, Tortosa, Avelina, Mira, Helena, Alonso, Marta M., Gómez-Manzano, Candelaria, Graus, Francesc, Sulman, Erik P., Piao, Xianhua, Nakano, Ichiro, Prat, Aleix, Bhat, Krishna P., de la Iglesia, Núria
Published in Cell reports (Cambridge) (21.11.2017)
Published in Cell reports (Cambridge) (21.11.2017)
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A multivariable prognostic score to guide systemic therapy in early-stage HER2-positive breast cancer: a retrospective study with an external evaluation
Prat, Aleix, Guarneri, Valentina, Paré, Laia, Griguolo, Gaia, Pascual, Tomás, Dieci, Maria V, Chic, Núria, González-Farré, Blanca, Frassoldati, Antonio, Sanfeliu, Esther, Cejalvo, Juan M, Muñoz, Montserrat, Bisagni, Giancarlo, Brasó-Maristany, Fara, Urso, Loredana, Vidal, Maria, Brandes, Alba A, Adamo, Barbara, Musolino, Antonino, Miglietta, Federica, Conte, Benedetta, Oliveira, Mafalda, Saura, Cristina, Pernas, Sònia, Alarcón, Jesús, Llombart-Cussac, Antonio, Cortés, Javier, Manso, Luis, López, Rafael, Ciruelos, Eva, Schettini, Francesco, Villagrasa, Patricia, Carey, Lisa A, Perou, Charles M, Piacentini, Federico, D'Amico, Roberto, Tagliafico, Enrico, Parker, Joel S, Conte, Pierfranco
Published in The lancet oncology (01.11.2020)
Published in The lancet oncology (01.11.2020)
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Gene expression profiles of breast cancer metastasis according to organ site
Brasó‐Maristany, Fara, Paré, Laia, Chic, Nuria, Martínez‐Sáez, Olga, Pascual, Tomás, Mallafré‐Larrosa, Meritxell, Schettini, Francesco, González‐Farré, Blanca, Sanfeliu, Esther, Martínez, Débora, Galván, Patricia, Barnadas, Esther, Salinas, Belinda, Tolosa, Pablo, Ciruelos, Eva, Carcelero, Esther, Guillén, Cecilia, Adamo, Barbara, Moreno, Reinaldo, Vidal, Maria, Muñoz, Montserrat, Prat, Aleix
Published in Molecular oncology (01.01.2022)
Published in Molecular oncology (01.01.2022)
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Circulating tumor DNA reveals complex biological features with clinical relevance in metastatic breast cancer
Prat, Aleix, Brasó-Maristany, Fara, Martínez-Sáez, Olga, Sanfeliu, Esther, Xia, Youli, Bellet, Meritxell, Galván, Patricia, Martínez, Débora, Pascual, Tomás, Marín-Aguilera, Mercedes, Rodríguez, Anna, Chic, Nuria, Adamo, Barbara, Paré, Laia, Vidal, Maria, Margelí, Mireia, Ballana, Ester, Gómez-Rey, Marina, Oliveira, Mafalda, Felip, Eudald, Matito, Judit, Sánchez-Bayona, Rodrigo, Suñol, Anna, Saura, Cristina, Ciruelos, Eva, Tolosa, Pablo, Muñoz, Montserrat, González-Farré, Blanca, Villagrasa, Patricia, Parker, Joel S., Perou, Charles M., Vivancos, Ana
Published in Nature communications (01.03.2023)
Published in Nature communications (01.03.2023)
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Safety, activity, and molecular heterogeneity following neoadjuvant non-pegylated liposomal doxorubicin, paclitaxel, trastuzumab, and pertuzumab in HER2-positive breast cancer (Opti-HER HEART): an open-label, single-group, multicenter, phase 2 trial
Gavilá, Joaquín, Oliveira, Mafalda, Pascual, Tomás, Perez-Garcia, Jose, Gonzàlez, Xavier, Canes, Jordi, Paré, Laia, Calvo, Isabel, Ciruelos, Eva, Muñoz, Montserrat, Virizuela, Juan A, Ruiz, Isabel, Andrés, Raquel, Perelló, Antonia, Martínez, Jerónimo, Morales, Serafín, Marín-Aguilera, Mercedes, Martínez, Débora, Quero, Juan C, Llombart-Cussac, Antonio, Prat, Aleix
Published in BMC medicine (09.01.2019)
Published in BMC medicine (09.01.2019)
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SOLTI-1805 TOT-HER3 Study Concept: A Window-of-Opportunity Trial of Patritumab Deruxtecan, a HER3 Directed Antibody Drug Conjugate, in Patients With Early Breast Cancer
Pascual, Tomás, Oliveira, Mafalda, Ciruelos, Eva, Bellet Ezquerra, Meritxell, Saura, Cristina, Gavilá, Joaquin, Pernas, Sonia, Muñoz, Montserrat, Vidal, Maria J, Margelí Vila, Mireia, Cejalvo, Juan M, González-Farré, Blanca, Espinosa-Bravo, Martin, Cruz, Josefina, Salvador-Bofill, Francisco Javier, Guerra, Juan Antonio, Luna Barrera, Ana María, Arumi de Dios, Miriam, Esker, Stephen, Fan, Pang-Dian, Martínez-Sáez, Olga, Villacampa, Guillermo, Paré, Laia, Ferrero-Cafiero, Juan M, Villagrasa, Patricia, Prat, Aleix
Published in Frontiers in oncology (23.04.2021)
Published in Frontiers in oncology (23.04.2021)
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The BRCA1 Pseudogene Negatively Regulates Antitumor Responses through Inhibition of Innate Immune Defense Mechanisms
Han, Yoo Jane, Zhang, Jing, Lee, Jung-Hyun, Mason, Jennifer M, Karginova, Olga, Yoshimatsu, Toshio F, Hao, Qinyu, Hurley, Ian, Brunet, Laia Paré, Prat, Aleix, Prasanth, Kannanganattu V, Gack, Michaela U, Olopade, Olufunmilayo I
Published in Cancer research (Chicago, Ill.) (15.03.2021)
Published in Cancer research (Chicago, Ill.) (15.03.2021)
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Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population
Gómez-Miragaya, Jorge, Palafox, Marta, Paré, Laia, Yoldi, Guillermo, Ferrer, Irene, Vila, Sergi, Galván, Patricia, Pellegrini, Pasquale, Pérez-Montoyo, Hector, Igea, Ana, Muñoz, Purificación, Esteller, Manel, Nebreda, Angel R., Urruticoechea, Ander, Morilla, Idoia, Pernas, Sonia, Climent, Fina, Soler-Monso, María Teresa, Petit, Ana, Serra, Violeta, Prat, Aleix, González-Suárez, Eva
Published in Stem cell reports (09.05.2017)
Published in Stem cell reports (09.05.2017)
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First Nationwide Molecular Screening Program in Spain for Patients With Advanced Breast Cancer: Results From the AGATA SOLTI-1301 Study
Pernas, Sonia, Villagrasa, Patricia, Vivancos, Ana, Scaltriti, Maurizio, Rodón, Jordi, Burgués, Octavio, Nuciforo, Paolo, Canes, Jordi, Paré, Laia, Dueñas, Marta, Vidal, Maria, Cejalvo, Juan Miguel, Perelló, Antonia, Llommbard-Cussac, Antonio, Dorca, Joan, Montaño, Alvaro, Pascual, Tomás, Oliveira, Mafalda, Ribas, Gloria, Rapado, Inmaculada, Prat, Aleix, Ciruelos, Eva
Published in Frontiers in oncology (04.11.2021)
Published in Frontiers in oncology (04.11.2021)
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Neoadjuvant eribulin in HER2-negative early-stage breast cancer (SOLTI-1007-NeoEribulin): a multicenter, two-cohort, non-randomized phase II trial
Pascual, Tomás, Oliveira, Mafalda, Villagrasa, Patricia, Ortega, Vanesa, Paré, Laia, Bermejo, Begoña, Morales, Serafín, Amillano, Kepa, López, Rafael, Galván, Patricia, Canes, Jordi, Salvador, Fernando, Nuciforo, Paolo, Rubio, Isabel T., Llombart-Cussac, Antonio, Di Cosimo, Serena, Baselga, José, Harbeck, Nadia, Prat, Aleix, Cortés, Javier
Published in NPJ breast cancer (25.11.2021)
Published in NPJ breast cancer (25.11.2021)
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The temporal mutational and immune tumour microenvironment remodelling of HER2-negative primary breast cancers
De Mattos-Arruda, Leticia, Cortes, Javier, Blanco-Heredia, Juan, Tiezzi, Daniel G., Villacampa, Guillermo, Gonçalves-Ribeiro, Samuel, Paré, Laia, Souza, Carla Anjos, Ortega, Vanesa, Sammut, Stephen-John, Cusco, Pol, Fasani, Roberta, Chin, Suet-Feung, Perez-Garcia, Jose, Dienstmann, Rodrigo, Nuciforo, Paolo, Villagrasa, Patricia, Rubio, Isabel T., Prat, Aleix, Caldas, Carlos
Published in NPJ breast cancer (07.06.2021)
Published in NPJ breast cancer (07.06.2021)
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A PAM50-Based Chemoendocrine Score for Hormone Receptor-Positive Breast Cancer with an Intermediate Risk of Relapse
Prat, Aleix, Lluch, Ana, Turnbull, Arran K, Dunbier, Anita K, Calvo, Lourdes, Albanell, Joan, de la Haba-Rodríguez, Juan, Arcusa, Angels, Chacón, José Ignacio, Sánchez-Rovira, Pedro, Plazaola, Arrate, Muñoz, Montserrat, Paré, Laia, Parker, Joel S, Ribelles, Nuria, Jimenez, Begoña, Bin Aiderus, Abdul Aziz, Caballero, Rosalía, Adamo, Barbara, Dowsett, Mitch, Carrasco, Eva, Martín, Miguel, Dixon, J Michael, Perou, Charles M, Alba, Emilio
Published in Clinical cancer research (15.06.2017)
Published in Clinical cancer research (15.06.2017)
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