Impaired Levels of Gangliosides in the Corpus Callosum of Huntington Disease Animal Models
Di Pardo, Alba, Amico, Enrico, Maglione, Vittorio
Published in Frontiers in neuroscience (06.10.2016)
Published in Frontiers in neuroscience (06.10.2016)
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De novo Synthesis of Sphingolipids Is Defective in Experimental Models of Huntington's Disease
Di Pardo, Alba, Basit, Abdul, Armirotti, Andrea, Amico, Enrico, Castaldo, Salvatore, Pepe, Giuseppe, Marracino, Federico, Buttari, Fabio, Digilio, Anna F, Maglione, Vittorio
Published in Frontiers in neuroscience (19.12.2017)
Published in Frontiers in neuroscience (19.12.2017)
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Liver specific inactivation of carboxylesterase 3/triacylglycerol hydrolase decreases blood lipids without causing severe steatosis in mice
Lian, Jihong, Wei, Enhui, Wang, Shu Pei, Quiroga, Ariel D., Li, Lena, Di Pardo, Alba, van der Veen, Jelske, Sipione, Simonetta, Mitchell, Grant A., Lehner, Richard
Published in Hepatology (Baltimore, Md.) (01.12.2012)
Published in Hepatology (Baltimore, Md.) (01.12.2012)
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Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model
Bichell, Terry Jo V., Wegrzynowicz, Michal, Tipps, K. Grace, Bradley, Emma M., Uhouse, Michael A., Bryan, Miles, Horning, Kyle, Fisher, Nicole, Dudek, Karrie, Halbesma, Timothy, Umashanker, Preethi, Stubbs, Andrew D., Holt, Hunter K., Kwakye, Gunnar F., Tidball, Andrew M., Colbran, Roger J., Aschner, Michael, Neely, M. Diana, Di Pardo, Alba, Maglione, Vittorio, Osmand, Alexander, Bowman, Aaron B.
Published in Biochimica et biophysica acta (01.06.2017)
Published in Biochimica et biophysica acta (01.06.2017)
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Cohort analysis of novel SPAST variants in SPG4 patients and implementation of in vitro and in vivo studies to identify the pathogenic mechanism caused by splicing mutations
Ferese, Rosangela, Scala, Simona, Suppa, Antonio, Campopiano, Rosa, Asci, Francesco, Zampogna, Alessandro, Chiaravalloti, Maria Antonietta, Griguoli, Annamaria, Storto, Marianna, Pardo, Alba Di, Giardina, Emiliano, Zampatti, Stefania, Fornai, Francesco, Novelli, Giuseppe, Fanelli, Mirco, Zecca, Chiara, Logroscino, Giancarlo, Centonze, Diego, Gambardella, Stefano
Published in Frontiers in neurology (07.12.2023)
Published in Frontiers in neurology (07.12.2023)
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DNA damage, homology-directed repair, and DNA methylation
Cuozzo, Concetta, Porcellini, Antonio, Angrisano, Tiziana, Morano, Annalisa, Lee, Bongyong, Di Pardo, Alba, Messina, Samantha, Iuliano, Rodolfo, Fusco, Alfredo, Santillo, Maria R, Muller, Mark T, Chiariotti, Lorenzo, Gottesman, Max E, Avvedimento, Enrico V
Published in PLoS genetics (01.07.2007)
Published in PLoS genetics (01.07.2007)
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Resistin Impairs Insulin-Evoked Vasodilation
GENTILE, Maria Teresa, VECCHIONE, Carmine, FRATI, Giacomo, LEMBOL, Giuseppe, MARINO, Gennaro, ARETINI, Alessandra, DI PARDO, Alba, ANTENUCCI, Giovanna, MAFFEI, Angelo, CIFELLI, Giuseppe, IORIO, Luca, LANDOLFI, Alessandro
Published in Diabetes (New York, N.Y.) (01.03.2008)
Published in Diabetes (New York, N.Y.) (01.03.2008)
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Pridopidine, a dopamine stabilizer, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model
Squitieri, Ferdinando, Di Pardo, Alba, Favellato, Mariagrazia, Amico, Enrico, Maglione, Vittorio, Frati, Luigi
Published in Journal of cellular and molecular medicine (01.11.2015)
Published in Journal of cellular and molecular medicine (01.11.2015)
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I08 Passive immunization, with the anti-huntingtin aggregate antibody EM48, is beneficial in R6/2 mouse model
Pepe, Giuseppe, Capocci, Luca, Marracino, Federico, Cicco, Clotilde Di, Scarselli, Pamela, Parlato, Rosanna, Pardo, Alba Di, Maglione, Vittorio
Published in Journal of neurology, neurosurgery and psychiatry (12.09.2022)
Published in Journal of neurology, neurosurgery and psychiatry (12.09.2022)
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I18 Treatment with THI, an inhibitor of sphingosine-1-phosphate lyase (SGPL1), modulates glycosphingolipid metabolism and results therapeutically effective in a mouse model of Huntington’s disease
Pepe, Giuseppe, Capocci, Luca, Marracino, Federico, Realini, Natalia, Scarselli, Pamela, Cicco, Clotilde Di, Armirotti, Andrea, Parlato, Rosanna, Pardo, Alba Di, Maglione, Vittorio
Published in Journal of neurology, neurosurgery and psychiatry (12.09.2022)
Published in Journal of neurology, neurosurgery and psychiatry (12.09.2022)
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An activator of voltage-gated K + channels Kv1.1 as a therapeutic candidate for episodic ataxia type 1
Servettini, Ilenio, Talani, Giuseppe, Megaro, Alfredo, Setzu, Maria Dolores, Biggio, Francesca, Briffa, Michelle, Guglielmi, Luca, Savalli, Nicoletta, Binda, Francesca, Delicata, Francis, Bru-Mercier, Gilles, Vassallo, Neville, Maglione, Vittorio, Cauchi, Ruben J, Di Pardo, Alba, Collu, Maria, Imbrici, Paola, Catacuzzeno, Luigi, D'Adamo, Maria Cristina, Olcese, Riccardo, Pessia, Mauro
Published in Proceedings of the National Academy of Sciences - PNAS (01.08.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (01.08.2023)
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Journal Article
Mitochondrial Respiration Changes in R6/2 Huntington's Disease Model Mice during Aging in a Brain Region Specific Manner
Burtscher, Johannes, Di Pardo, Alba, Maglione, Vittorio, Schwarzer, Christoph, Squitieri, Ferdinando
Published in International journal of molecular sciences (30.07.2020)
Published in International journal of molecular sciences (30.07.2020)
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I19 The defective metabolism of polysialic acid (polysia) may represent an effective therapeutic target in hd pre-clinical models
Pepe, Giuseppe, Capocci, Luca, Marracino, Federico, Moons, Sam J, Sönmez, Aynur, Świtońska-Kurkowska, Karolina, Scarselli, Pamela, Cicco, Clotilde Di, Figiel, Maciej, Boltje, Thomas J, Parlato, Rosanna, Pardo, Alba Di, Maglione, Vittorio
Published in Journal of neurology, neurosurgery and psychiatry (12.09.2022)
Published in Journal of neurology, neurosurgery and psychiatry (12.09.2022)
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Journal Article
Impairment of blood-brain barrier is an early event in R6/2 mouse model of Huntington Disease
Di Pardo, Alba, Amico, Enrico, Scalabrì, Francesco, Pepe, Giuseppe, Castaldo, Salvatore, Elifani, Francesca, Capocci, Luca, De Sanctis, Claudia, Comerci, Laura, Pompeo, Francesco, D’Esposito, Maurizio, Filosa, Stefania, Crispi, Stefania, Maglione, Vittorio
Published in Scientific reports (24.01.2017)
Published in Scientific reports (24.01.2017)
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Curcumin-Loaded Nanoparticles Based on Amphiphilic Hyaluronan-Conjugate Explored as Targeting Delivery System for Neurodegenerative Disorders
Pepe, Giuseppe, Calce, Enrica, Verdoliva, Valentina, Saviano, Michele, Maglione, Vittorio, Di Pardo, Alba, De Luca, Stefania
Published in International journal of molecular sciences (23.11.2020)
Published in International journal of molecular sciences (23.11.2020)
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Journal Article
Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology
Ziller, Michael J., Ortega, Juan A., Quinlan, Katharina A., Santos, David P., Gu, Hongcang, Martin, Eric J., Galonska, Christina, Pop, Ramona, Maidl, Susanne, Di Pardo, Alba, Huang, Mei, Meltzer, Herbert Y., Gnirke, Andreas, Heckman, C.J., Meissner, Alexander, Kiskinis, Evangelos
Published in Cell stem cell (05.04.2018)
Published in Cell stem cell (05.04.2018)
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Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice
Di Pardo, Alba, Maglione, Vittorio, Alpaugh, Melanie, Horkey, Melanie, Atwal, Randy S, Sassone, Jenny, Ciammola, Andrea, Steffan, Joan S, Fouad, Karim, Truant, Ray, Sipione, Simonetta
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2012)
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Treatment with the Glycosphingolipid Modulator THI Rescues Myelin Integrity in the Striatum of R6/2 HD Mice
Pepe, Giuseppe, Lenzi, Paola, Capocci, Luca, Marracino, Federico, Pizzati, Ludovica, Scarselli, Pamela, Di Pardo, Alba, Fornai, Francesco, Maglione, Vittorio
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
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