Acute myeloid leukemia and myelodysplastic syndromes in older adults
Klepin, Heidi D, Rao, Arati V, Pardee, Timothy S
Published in Journal of clinical oncology (20.08.2014)
Published in Journal of clinical oncology (20.08.2014)
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Geriatric assessment predicts survival for older adults receiving induction chemotherapy for acute myelogenous leukemia
Klepin, Heidi D., Geiger, Ann M., Tooze, Janet A., Kritchevsky, Stephen B., Williamson, Jeff D., Pardee, Timothy S., Ellis, Leslie R., Powell, Bayard L.
Published in Blood (23.05.2013)
Published in Blood (23.05.2013)
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Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label, dose-escalation, phase 1 trial
Alistar, Angela, Dr, Morris, Bonny B, MSPH, Desnoyer, Rodwige, MD, Klepin, Heidi D, MD, Hosseinzadeh, Keyanoosh, MD, Clark, Clancy, MD, Cameron, Amy, PA, Leyendecker, John, Prof, D'Agostino, Ralph, Prof, Topaloglu, Umit, PhD, Boteju, Lakmal W, PhD, Boteju, Asela R, ASc, Shorr, Rob, PhD, Zachar, Zuzana, PhD, Bingham, Paul M, PhD, Ahmed, Tamjeed, MD, Crane, Sandrine, MD, Shah, Riddhishkumar, MD, Migliano, John J, MD, Pardee, Timothy S, MD, Miller, Lance, PhD, Hawkins, Gregory, PhD, Jin, Guangxu, PhD, Zhang, Wei, Prof, Pasche, Boris, Prof
Published in The lancet oncology (01.06.2017)
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Mitochondria in cancer metabolism, an organelle whose time has come?
Anderson, Rebecca G., Ghiraldeli, Lais P., Pardee, Timothy S.
Published in Biochimica et biophysica acta. Reviews on cancer (01.08.2018)
Published in Biochimica et biophysica acta. Reviews on cancer (01.08.2018)
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A Phase II Clinical Trial of CPI-613 in Patients with Relapsed or Refractory Small Cell Lung Carcinoma
Lycan, Thomas W, Pardee, Timothy S, Petty, William J, Bonomi, Marcelo, Alistar, Angela, Lamar, Zanetta S, Isom, Scott, Chan, Michael D, Miller, Antonius A, Ruiz, Jimmy
Published in PloS one (12.10.2016)
Published in PloS one (12.10.2016)
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A Phase I Study of CPI-613 in Combination with High-Dose Cytarabine and Mitoxantrone for Relapsed or Refractory Acute Myeloid Leukemia
Pardee, Timothy S, Anderson, Rebecca G, Pladna, Kristin M, Isom, Scott, Ghiraldeli, Lais P, Miller, Lance D, Chou, Jeff W, Jin, Guangxu, Zhang, Wei, Ellis, Leslie R, Berenzon, Dmitriy, Howard, Dianna S, Hurd, David D, Manuel, Megan, Dralle, Sarah, Lyerly, Susan, Powell, Bayard L
Published in Clinical cancer research (01.05.2018)
Published in Clinical cancer research (01.05.2018)
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Geriatric assessment and survival among older adults receiving postremission therapy for acute myeloid leukemia
Saad, Mohammed, Loh, Kah Poh, Tooze, Janet A., Pardee, Timothy S., Ellis, Leslie R., Powell, Bayard L., Bhave, Rupali Roy, Geiger, Ann M., Williamson, Jeff D., Kritchevsky, Stephen, Klepin, Heidi D.
Published in Blood (03.12.2020)
Published in Blood (03.12.2020)
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Devimistat in combination with high dose cytarabine and mitoxantrone compared with high dose cytarabine and mitoxantrone in older patients with relapsed/refractory acute myeloid leukemia: ARMADA 2000 Phase III study
Pardee, Timothy S, Luther, Sanjeev, Buyse, Marc, Powell, Bayard L, Cortes, Jorge
Published in Future oncology (London, England) (01.10.2019)
Published in Future oncology (London, England) (01.10.2019)
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Phase II trial of cytarabine and mitoxantrone with devimistat in acute myeloid leukemia
Anderson, Rebecca, Miller, Lance D., Isom, Scott, Chou, Jeff W., Pladna, Kristin M., Schramm, Nathaniel J., Ellis, Leslie R., Howard, Dianna S., Bhave, Rupali R., Manuel, Megan, Dralle, Sarah, Lyerly, Susan, Powell, Bayard L., Pardee, Timothy S.
Published in Nature communications (30.03.2022)
Published in Nature communications (30.03.2022)
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Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
Lin, Kevin H., Xie, Abigail, Rutter, Justine C., Ahn, Yeong-ran, Lloyd-Cowden, Julia M., Nichols, Amanda G., Soderquist, Ryan S., Koves, Timothy R., Muoio, Deborah M., MacIver, Nancie J., Lamba, Jatinder K., Pardee, Timothy S., McCall, Chad M., Rizzieri, David A., Wood, Kris C.
Published in Cell metabolism (07.05.2019)
Published in Cell metabolism (07.05.2019)
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A Phase III open-label trial to evaluate efficacy and safety of CPI-613 plus modified FOLFIRINOX (mFFX) versus FOLFIRINOX (FFX) in patients with metastatic adenocarcinoma of the pancreas
Philip, Philip A, Buyse, Marc E, Alistar, Angela T, Rocha Lima, Caio MSPR, Luther, Sanjeev, Pardee, Timothy S, Van Cutsem, Eric
Published in Future oncology (London, England) (01.10.2019)
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A phase I study of the first-in-class antimitochondrial metabolism agent, CPI-613, in patients with advanced hematologic malignancies
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Published in Clinical cancer research (15.10.2014)
Published in Clinical cancer research (15.10.2014)
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Mouse models of human AML accurately predict chemotherapy response
Zuber, Johannes, Radtke, Ina, Pardee, Timothy S, Zhao, Zhen, Rappaport, Amy R, Luo, Weijun, McCurrach, Mila E, Yang, Miao-Miao, Dolan, M Eileen, Kogan, Scott C, Downing, James R, Lowe, Scott W
Published in Genes & development (01.04.2009)
Published in Genes & development (01.04.2009)
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Effect of Intensive Chemotherapy on Physical, Cognitive, and Emotional Health of Older Adults with Acute Myeloid Leukemia
Klepin, Heidi D., Tooze, Janet A., Pardee, Timothy S., Ellis, Leslie R., Berenzon, Dmitriy, Mihalko, Shannon L., Danhauer, Suzanne C., Rao, Arati V., Wildes, Tanya M., Williamson, Jeff D., Powell, Bayard L., Kritchevsky, Stephen B.
Published in Journal of the American Geriatrics Society (JAGS) (01.10.2016)
Published in Journal of the American Geriatrics Society (JAGS) (01.10.2016)
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Improving nucleoside analogs via lipid conjugation: Is fatter any better?
Alexander, Peter, Kucera, Gregory, Pardee, Timothy S
Published in Critical reviews in oncology/hematology (01.04.2016)
Published in Critical reviews in oncology/hematology (01.04.2016)
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Pyruvate Dehydrogenase Inhibition Leads to Decreased Glycolysis, Increased Reliance on Gluconeogenesis and Alternative Sources of Acetyl-CoA in Acute Myeloid Leukemia
Anderson, Rebecca, Pladna, Kristin M, Schramm, Nathaniel J, Wheeler, Frances B, Kridel, Steven, Pardee, Timothy S
Published in Cancers (12.01.2023)
Published in Cancers (12.01.2023)
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Safety and tolerability of AMG 330 in adults with relapsed/refractory AML: a phase 1a dose-escalation study
Ravandi, Farhad, Subklewe, Marion, Walter, Roland B, Vachhani, Pankit, Ossenkoppele, Gert, Buecklein, Veit, Döhner, Hartmut, Jongen-Lavrencic, Mojca, Baldus, Claudia D, Fransecky, Lars, Pardee, Timothy S, Kantarjian, Hagop, Yen, Priscilla K, Mukundan, Lata, Panwar, Bharat, Yago, Marc R, Agarwal, Suresh, Khaldoyanidi, Sophia K, Stein, Anthony
Published in Leukemia & lymphoma (01.09.2024)
Published in Leukemia & lymphoma (01.09.2024)
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