Transcriptional Amplification in Tumor Cells with Elevated c-Myc
Lin, Charles Y., Lovén, Jakob, Rahl, Peter B., Paranal, Ronald M., Burge, Christopher B., Bradner, James E., Lee, Tong Ihn, Young, Richard A.
Published in Cell (28.09.2012)
Published in Cell (28.09.2012)
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Journal Article
NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis
Brown, Jonathan D., Lin, Charles Y., Duan, Qiong, Griffin, Gabriel, Federation, Alexander J., Paranal, Ronald M., Bair, Steven, Newton, Gail, Lichtman, Andrew H., Kung, Andrew L., Yang, Tianlun, Wang, Hong, Luscinskas, Francis W., Croce, Kevin J., Bradner, James E., Plutzky, Jorge
Published in Molecular cell (23.10.2014)
Published in Molecular cell (23.10.2014)
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Journal Article
BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia
Ott, Christopher J., Kopp, Nadja, Bird, Liat, Paranal, Ronald M., Qi, Jun, Bowman, Teresa, Rodig, Scott J., Kung, Andrew L., Bradner, James E., Weinstock, David M.
Published in Blood (04.10.2012)
Published in Blood (04.10.2012)
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Journal Article
Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma
Hideshima, Teru, Qi, Jun, Paranal, Ronald M., Tang, Weiping, Greenberg, Edward, West, Nathan, Colling, Meaghan E., Estiu, Guillermina, Mazitschek, Ralph, Perry, Jennifer A., Ohguchi, Hiroto, Cottini, Francesca, Mimura, Naoya, Görgün, Güllü, Tai, Yu-Tzu, Richardson, Paul G., Carrasco, Ruben D., Wiest, Olaf, Schreiber, Stuart L., Anderson, Kenneth C., Bradner, James E.
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.2016)
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Journal Article
BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Delmore, Jake E., Issa, Ghayas C., Lemieux, Madeleine E., Rahl, Peter B., Shi, Junwei, Jacobs, Hannah M., Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M., Qi, Jun, Chesi, Marta, Schinzel, Anna C., McKeown, Michael R., Heffernan, Timothy P., Vakoc, Christopher R., Bergsagel, P. Leif, Ghobrial, Irene M., Richardson, Paul G., Young, Richard A., Hahn, William C., Anderson, Kenneth C., Kung, Andrew L., Bradner, James E., Mitsiades, Constantine S.
Published in Cell (16.09.2011)
Published in Cell (16.09.2011)
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Journal Article
Epigenomic analysis of formalin-fixed paraffin-embedded samples by CUT&Tag
Henikoff, Steven, Henikoff, Jorja G., Ahmad, Kami, Paranal, Ronald M., Janssens, Derek H., Russell, Zachary R., Szulzewsky, Frank, Kugel, Sita, Holland, Eric C.
Published in Nature communications (22.09.2023)
Published in Nature communications (22.09.2023)
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Journal Article
Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition
Weigert, Oliver, Lane, Andrew A, Bird, Liat, Kopp, Nadja, Chapuy, Bjoern, van Bodegom, Diederik, Toms, Angela V, Marubayashi, Sachie, Christie, Amanda L, McKeown, Michael, Paranal, Ronald M, Bradner, James E, Yoda, Akinori, Gaul, Christoph, Vangrevelinghe, Eric, Romanet, Vincent, Murakami, Masato, Tiedt, Ralph, Ebel, Nicolas, Evrot, Emeline, De Pover, Alain, Régnier, Catherine H, Erdmann, Dirk, Hofmann, Francesco, Eck, Michael J, Sallan, Stephen E, Levine, Ross L, Kung, Andrew L, Baffert, Fabienne, Radimerski, Thomas, Weinstock, David M
Published in The Journal of experimental medicine (13.02.2012)
Published in The Journal of experimental medicine (13.02.2012)
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Journal Article
The oral manifestations of syphilitic disease: a case report
Streight, Kaitlyn L, Paranal, Ronald M, Musher, Daniel M
Published in Journal of medical case reports (26.07.2019)
Published in Journal of medical case reports (26.07.2019)
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Journal Article
Impact of luteinizing hormone suppression on hematopoietic recovery after intensive chemotherapy in patients with leukemia
Dalle, Iman Abou, Paranal, Ronald, Zarka, Jabra, Paul, Shilpa, Sasaki, Koji, Li, Wen, Ning, Jing, Short, Nicholas J, Ohanian, Maro, Cortes, Jorge E, Jabbour, Elias J, Issa, Ghayas C
Published in Haematologica (Roma) (01.04.2021)
Published in Haematologica (Roma) (01.04.2021)
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Journal Article
Development of a Potent and Selective HDAC8 Inhibitor
Ingham, Oscar J, Paranal, Ronald M, Smith, William B, Escobar, Randolph A, Yueh, Han, Snyder, Tracy, Porco, John A, Bradner, James E, Beeler, Aaron B
Published in ACS medicinal chemistry letters (13.10.2016)
Published in ACS medicinal chemistry letters (13.10.2016)
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Journal Article
Synthesis and Biological Evaluation of JAHAs: Ferrocene-Based Histone Deacetylase Inhibitors
Spencer, John, Amin, Jahangir, Wang, Minghua, Packham, Graham, Alwi, Sharifah S. Syed, Tizzard, Graham J, Coles, Simon J, Paranal, Ronald M, Bradner, James E, Heightman, Tom D
Published in ACS medicinal chemistry letters (12.05.2011)
Published in ACS medicinal chemistry letters (12.05.2011)
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Journal Article
Synthesis of hybrid anticancer agents based on kinase and histone deacetylase inhibitors
Patel, Hiren, Chuckowree, Irina, Coxhead, Peter, Guille, Matthew, Wang, Minghua, Zuckermann, Alexandra, Williams, Robin S. B., Librizzi, Mariangela, Paranal, Ronald M., Bradner, James E., Spencer, John
Published in MedChemComm (01.12.2014)
Published in MedChemComm (01.12.2014)
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Journal Article
A cyclodextrin-capped histone deacetylase inhibitor
Amin, Jahangir, Puglisi, Antonino, Clarke, James, Milton, John, Wang, Minghua, Paranal, Ronald M., Bradner, James E., Spencer, John
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
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Journal Article
Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation
Frumm, Stacey M., Fan, Zi Peng, Ross, Kenneth N., Duvall, Jeremy R., Gupta, Supriya, VerPlank, Lynn, Suh, Byung-Chul, Holson, Edward, Wagner, Florence F., Smith, William B., Paranal, Ronald M., Bassil, Christopher F., Qi, Jun, Roti, Giovanni, Kung, Andrew L., Bradner, James E., Tolliday, Nicola, Stegmaier, Kimberly
Published in Chemistry & biology (23.05.2013)
Published in Chemistry & biology (23.05.2013)
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Journal Article
NF-kB directs dynamic super enhancer formation in inflammation and atherogenesis
Brown, Jonathan D., Lin, Charles Y., Duan, Qiong, Griffin, Gabriel, Federation, Alexander, Paranal, Ronald M., Bair, Steven, Newton, Gail, Lichtman, Andrew, Kung, Andrew, Yang, Tianlun, Wang, Hong, Luscinskas, Francis W., Croce, Kevin, Bradner, James E., Plutzky, Jorge
Published in Molecular cell (25.09.2014)
Published in Molecular cell (25.09.2014)
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Journal Article
Impact of luteinizing hormone suppression on hematopoietic recovery after intensive chemotherapy in patients with leukemia
Aboudalle, Iman, Paranal, Ronald, Paul, Shilpa, Li, Wen, Ning, Jing, Cortes, Jorge E., Jabbour, Elias, Kantarjian, Hagop M., Issa, Ghayas C.
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
Characterization of Changes in the T-Cell Receptor Repertoire in Patients with Acute Myeloid Leukemia with Durable Remission Following Allogeneic Stem Cell Transplant
Paranal, Ronald M., Kantarjian, Hagop M., Reuben, Alexandre, Kerros, Celine, Koppikar, Priya, Little, Latasha, Gumbs, Curtis, Short, Nicholas J., Cortes, Jorge E., Jabbour, Elias, Molldrem, Jeffrey J., Futreal, P. Andrew, Issa, Ghayas C.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
AML-405: T-Cell Dynamics Associated with Outcomes in Acute Myeloid Leukemia Before and After Allogeneic Stem Cell Transplant
Paranal, Ronald, Kantarjian, Hagop, Little, Latasha, Gumbs, Curtis, Short, Nicholas, Jabbour, Elias, Futreal, P. Andrew, Issa, Ghayas
Published in Clinical lymphoma, myeloma and leukemia (01.09.2020)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2020)
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Journal Article
Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs
Guerra-Bubb, Jennifer M., Bowers, Albert A., Smith, William B., Paranal, Ronald, Estiu, Guillermina, Wiest, Olaf, Bradner, James E., Williams, Robert M.
Published in Bioorganic & medicinal chemistry letters (01.11.2013)
Published in Bioorganic & medicinal chemistry letters (01.11.2013)
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Journal Article
Abstract 4610: Small molecule inhibitors of membrane-bound MCL-1 and BCL-2
Patel, Luv G., Paranal, Ronald M., Ryan, Jeremy, Sarosiek, Kristopher, Bradner, James E., Letai, Anthony
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article