Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease
di Domenico, Angelique, Carola, Giulia, Calatayud, Carles, Pons-Espinal, Meritxell, Muñoz, Juan Pablo, Richaud-Patin, Yvonne, Fernandez-Carasa, Irene, Gut, Marta, Faella, Armida, Parameswaran, Janani, Soriano, Jordi, Ferrer, Isidro, Tolosa, Eduardo, Zorzano, Antonio, Cuervo, Ana Maria, Raya, Angel, Consiglio, Antonella
Published in Stem cell reports (12.02.2019)
Published in Stem cell reports (12.02.2019)
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Journal Article
RNA-mediated toxicity in C9orf72 ALS and FTD
McEachin, Zachary T., Parameswaran, Janani, Raj, Nisha, Bassell, Gary J., Jiang, Jie
Published in Neurobiology of disease (01.11.2020)
Published in Neurobiology of disease (01.11.2020)
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Journal Article
Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent ISR in C9ORF72 FTD/ALS
Parameswaran, Janani, Zhang, Nancy, Braems, Elke, Tilahun, Kedamawit, Pant, Devesh C, Yin, Keena, Asress, Seneshaw, Heeren, Kara, Banerjee, Anwesha, Davis, Emma, Schwartz, Samantha L, Conn, Graeme L, Bassell, Gary J, Van Den Bosch, Ludo, Jiang, Jie
Published in eLife (19.04.2023)
Published in eLife (19.04.2023)
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Journal Article
Activating cannabinoid receptor 2 preserves axonal health through GSK-3[beta]/NRF2 axis in adrenoleukodystrophy
Parameswaran, Janani, Goicoechea, Leire, Planas-Serra, Laura, Pastor, Antoni, Ruiz, Montserrat, Calingasan, Noel Y, Guilera, Cristina
Published in Acta neuropathologica (01.08.2022)
Published in Acta neuropathologica (01.08.2022)
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Journal Article
Imbalanced mitochondrial dynamics contributes to the pathogenesis of X-linked adrenoleukodystrophy
Launay, Nathalie, Lopez-Erauskin, Jone, Bianchi, Patrizia, Guha, Sanjib, Parameswaran, Janani, Coppa, Andrea, Torreni, Lorenzo, Schlüter, Agatha, Fourcade, Stéphane, Paredes-Fuentes, Abraham J, Artuch, Rafael, Casasnovas, Carlos, Ruiz, Montserrat, Pujol, Aurora
Published in Brain (London, England : 1878) (03.06.2024)
Published in Brain (London, England : 1878) (03.06.2024)
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Journal Article
ALS‐linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain‐of‐function
Pant, Devesh C, Parameswaran, Janani, Rao, Lu, Loss, Isabel, Chilukuri, Ganesh, Parlato, Rosanna, Shi, Liang, Glass, Jonathan D, Bassell, Gary J, Koch, Philipp, Yilmaz, Rüstem, Weishaupt, Jochen H, Gennerich, Arne, Jiang, Jie
Published in EMBO reports (03.08.2022)
Published in EMBO reports (03.08.2022)
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Journal Article
The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance: A worm model for adrenoleukodystrophy
Coppa, Andrea, Guha, Sanjib, Fourcade, Stéphane, Parameswaran, Janani, Ruiz, Montserrat, Moser, Ann B., Schlüter, Agatha, Murphy, Michael P., Lizcano, Jose Miguel, Miranda-Vizuete, Antonio, Dalfó, Esther, Pujol, Aurora
Published in Free radical biology & medicine (20.05.2020)
Published in Free radical biology & medicine (20.05.2020)
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Journal Article
Activating cannabinoid receptor 2 preserves axonal health through GSK-3β/NRF2 axis in adrenoleukodystrophy
Parameswaran, Janani, Goicoechea, Leire, Planas-Serra, Laura, Pastor, Antoni, Ruiz, Montserrat, Calingasan, Noel Y., Guilera, Cristina, Aso, Ester, Boada, Jordi, Pamplona, Reinald, Portero-Otín, Manuel, de la Torre, Rafael, Ferrer, Isidre, Casasnovas, Carlos, Pujol, Aurora, Fourcade, Stéphane
Published in Acta neuropathologica (01.08.2022)
Published in Acta neuropathologica (01.08.2022)
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Journal Article
The peroxisomal fatty acid transporter pmp-4 is required in the C. elegans hypodermis for axonal maintenance
Coppa, Andrea, Guha, Sanjib, Fourcade, Stéphane, Parameswaran, Janani, Ruiz, Montserrat, Moser, Ann, Schlüter, Agatha, Murphy, Michael P., Lizcano, Jose Miguel, Miranda-Vizuete, Antonio, Dalfó, Esther, Pujol, Aurora
Published in Free radical biology & medicine (01.02.2020)
Published in Free radical biology & medicine (01.02.2020)
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Journal Article
Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2[alpha]-dependent ISR in C9ORF72 FTD/ALS
Parameswaran, Janani, Zhang, Nancy, Braems, Elke, Tilahun, Kedamawit, Pant, Devesh C, Yin, Keena, Asress, Seneshaw, Heeren, Kara, Banerjee, Anwesha, Davis, Emma, Schwartz, Samantha L, Conn, Graeme L, Bassell, Gary J, Van Den Bosch, Ludo, Jiang, Jie
Published in eLife (19.04.2023)
Published in eLife (19.04.2023)
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Journal Article
High‐dose biotin restores redox balance, energy and lipid homeostasis, and axonal health in a model of adrenoleukodystrophy
Fourcade, Stéphane, Goicoechea, Leire, Parameswaran, Janani, Schlüter, Agatha, Launay, Nathalie, Ruiz, Montserrat, Seyer, Alexandre, Colsch, Benoit, Calingasan, Noel Ylagan, Ferrer, Isidre, Beal, M. Flint, Sedel, Frédéric, Pujol, Aurora
Published in Brain pathology (Zurich, Switzerland) (01.09.2020)
Published in Brain pathology (Zurich, Switzerland) (01.09.2020)
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Journal Article
Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
Fourcade, Stéphane, Morató, Laia, Parameswaran, Janani, Ruiz, Montserrat, Ruiz‐Cortés, Tatiana, Jové, Mariona, Naudí, Alba, Martínez‐Redondo, Paloma, Dierssen, Mara, Ferrer, Isidre, Villarroya, Francesc, Pamplona, Reinald, Vaquero, Alejandro, Portero‐Otín, Manel, Pujol, Aurora
Published in Aging cell (01.12.2017)
Published in Aging cell (01.12.2017)
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Journal Article
Rare variants in MYH15 modify amyotrophic lateral sclerosis risk
Kim, Hyerim, Lim, Junghwa, Bao, Han, Jiao, Bin, Canon, Se Min, Epstein, Michael P, Xu, Keqin, Jiang, Jie, Parameswaran, Janani, Li, Yingjie, Moberg, Kenneth H, Landers, John E, Fournier, Christina, Allen, Emily G, Glass, Jonathan D, Wingo, Thomas S, Jin, Peng
Published in Human molecular genetics (15.07.2019)
Published in Human molecular genetics (15.07.2019)
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Journal Article
Loss of SIRT 2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
Fourcade, Stéphane, Morató, Laia, Parameswaran, Janani, Ruiz, Montserrat, Ruiz‐Cortés, Tatiana, Jové, Mariona, Naudí, Alba, Martínez‐Redondo, Paloma, Dierssen, Mara, Ferrer, Isidre, Villarroya, Francesc, Pamplona, Reinald, Vaquero, Alejandro, Portero‐Otín, Manel, Pujol, Aurora
Published in Aging cell (01.12.2017)
Published in Aging cell (01.12.2017)
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Journal Article
Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
Fourcade, Stéphane, Morató, Laia, Parameswaran, Janani, Ruiz, Montserrat, Ruiz-Cortés, Tatiana, Jove, Mariona, Naudi, Alba, Martínez Redondo, Paloma, Dierssen, Mara, Ferrer, Isidro (Ferrer Abizanda), Villarroya i Gombau, Francesc, Pamplona, Reinald, Vaquero García, Alejandro, Portero Otin, Manuel, Pujol Onofre, Aurora
Published in Aging cell (01.12.2017)
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Published in Aging cell (01.12.2017)
Journal Article
Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
Fourcade, Stéphane, Morató, Laia, Parameswaran, Janani, Ruiz, Montserrat, Ruiz-Cortés, Tatiana, Jove, Mariona, Naudi, Alba, Martínez Redondo, Paloma, Dierssen, Mara, Ferrer, Isidro (Ferrer Abizanda), Villarroya i Gombau, Francesc, Pamplona, Reinald, Vaquero García, Alejandro, Portero Otin, Manuel, Pujol Onofre, Aurora
Published in Aging cell (01.12.2017)
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Published in Aging cell (01.12.2017)
Journal Article
Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
Fourcade, Stéphane, Morató, Laia, Parameswaran, Janani, Ruiz, Montserrat, Ruiz-Cortés, Tatiana, Jove, Mariona, Naudi, Alba, Martínez Redondo, Paloma, Dierssen, Mara, Ferrer, Isidro (Ferrer Abizanda), Villarroya i Gombau, Francesc, Pamplona, Reinald, Vaquero García, Alejandro, Portero Otin, Manuel, Pujol Onofre, Aurora
Published in Aging cell (01.12.2017)
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Published in Aging cell (01.12.2017)
Journal Article
Patient-specific iPSC-derived astrocytes contribute to non-cell-autonomous neurodegeneration in Parkinson's disease
Domenico, Angelique Di, Carola, Giulia, Calatayud Aristoy, Carles, Pons-Espinal, Meritxell, Muñoz, Juan Pablo, Richaud-Patin, Yvonne, Fernandez-Carasa, Irene, Gut, Marta, Faella, Armida, Parameswaran, Janani, Soriano i Fradera, Jordi, Ferrer, Isidro (Ferrer Abizanda), Tolosa, Eduardo, Zorzano Olarte, Antonio, Cuervo, Ana Maria, Raya Chamorro, Ángel, Consiglio, Antonella
Published in Stem cell reports (12.02.2019)
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Published in Stem cell reports (12.02.2019)
Journal Article
Patient-specific iPSC-derived astrocytes contribute to non-cell-autonomous neurodegeneration in Parkinson's disease
Domenico, Angelique Di, Carola, Giulia, Calatayud Aristoy, Carles, Pons-Espinal, Meritxell, Muñoz, Juan Pablo, Richaud-Patin, Yvonne, Fernandez-Carasa, Irene, Gut, Marta, Faella, Armida, Parameswaran, Janani, Soriano i Fradera, Jordi, Ferrer, Isidro (Ferrer Abizanda), Tolosa, Eduardo, Zorzano Olarte, Antonio, Cuervo, Ana Maria, Raya Chamorro, Ángel, Consiglio, Antonella
Published in Stem cell reports (12.02.2019)
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Published in Stem cell reports (12.02.2019)
Journal Article
Patient-specific iPSC-derived astrocytes contribute to non-cell-autonomous neurodegeneration in Parkinson's disease
Domenico, Angelique Di, Carola, Giulia, Calatayud Aristoy, Carles, Pons-Espinal, Meritxell, Muñoz, Juan Pablo, Richaud-Patin, Yvonne, Fernandez-Carasa, Irene, Gut, Marta, Faella, Armida, Parameswaran, Janani, Soriano i Fradera, Jordi, Ferrer, Isidro (Ferrer Abizanda), Tolosa, Eduardo, Zorzano Olarte, Antonio, Cuervo, Ana Maria, Raya Chamorro, Ángel, Consiglio, Antonella
Published in Stem cell reports (12.02.2019)
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Published in Stem cell reports (12.02.2019)
Journal Article