Vascular smooth muscle cells in response to cholesterol crystals modulates inflammatory cytokines release and promotes neutrophil extracellular trap formation
Thazhathveettil, Jishamol, Kumawat, Ashok Kumar, Demirel, Isak, Sirsjö, Allan, Paramel, Geena Varghese
Published in Molecular medicine (Cambridge, Mass.) (22.03.2024)
Published in Molecular medicine (Cambridge, Mass.) (22.03.2024)
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Journal Article
NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis
Paramel Varghese, Geena, Folkersen, Lasse, Strawbridge, Rona J., Halvorsen, Bente, Yndestad, Arne, Ranheim, Trine, Krohg‐Sørensen, Kirsten, Skjelland, Mona, Espevik, Terje, Aukrust, Pål, Lengquist, Mariette, Hedin, Ulf, Jansson, Jan‐Håkan, Fransén, Karin, Hansson, Göran K., Eriksson, Per, Sirsjö, Allan
Published in Journal of the American Heart Association (01.05.2016)
Published in Journal of the American Heart Association (01.05.2016)
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Journal Article
Human Renal Fibroblasts, but Not Renal Epithelial Cells, Induce IL-1β Release during a Uropathogenic Escherichia coli Infection In Vitro
Kumawat, Ashok Kumar, Paramel, Geena Varghese, Demirel, Kartheyaene Jayaprakash, Demirel, Isak
Published in Cells (Basel, Switzerland) (13.12.2021)
Published in Cells (Basel, Switzerland) (13.12.2021)
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Journal Article
Inhibition of IL17A Using an Affibody Molecule Attenuates Inflammation in ApoE-Deficient Mice
Kumawat, Ashok Kumar, Zegeye, Mulugeta M, Paramel, Geena Varghese, Baumgartner, Roland, Gisterå, Anton, Amegavie, Obed, Hellberg, Sanna, Jin, Hong, Caravaca, April S, Söderström, Leif Å, Gudmundsdotter, Lindvi, Frejd, Fredrik Y, Ljungberg, Liza U, Olofsson, Peder S, Ketelhuth, Daniel F J, Sirsjö, Allan
Published in Frontiers in cardiovascular medicine (2022)
Published in Frontiers in cardiovascular medicine (2022)
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Journal Article
CARD8 gene encoding a protein of innate immunity is expressed in human atherosclerosis and associated with markers of inflammation
Paramel, Geena Varghese, Folkersen, Lasse, Strawbridge, Rona J, Elmabsout, Ali Ateia, Särndahl, Eva, Lundman, Pia, Jansson, Jan-Håkan, Hansson, Göran K, Sirsjö, Allan, Fransén, Karin
Published in Clinical science (1979) (01.10.2013)
Published in Clinical science (1979) (01.10.2013)
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Activation of the JAK/STAT3 and PI3K/AKT pathways are crucial for IL-6 trans-signaling-mediated pro-inflammatory response in human vascular endothelial cells
Zegeye, Mulugeta M, Lindkvist, Madelene, Fälker, Knut, Kumawat, Ashok K, Paramel, Geena, Grenegård, Magnus, Sirsjö, Allan, Ljungberg, Liza U
Published in Cell communication and signaling (05.09.2018)
Published in Cell communication and signaling (05.09.2018)
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Journal Article
Novel purine analogues regulate IL-1β release via inhibition of JAK activity in human aortic smooth muscle cells
Paramel, Geena V., Lindkvist, Madelene, Idosa, Berhane A., Sebina, Laila Sharon, Kardeby, Caroline, Fotopoulou, Theano, Pournara, Dimitra, Kritsi, Eftichia, Ifanti, Eleni, Zervou, Maria, Koufaki, Maria, Grenegård, Magnus, Fransén, Karin
Published in European journal of pharmacology (15.08.2022)
Published in European journal of pharmacology (15.08.2022)
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Journal Article
A novel purine analogue bearing nitrate ester prevents platelet activation by ROCK activity inhibition
Kardeby, Caroline, Paramel, Geena V., Pournara, Dimitra, Fotopoulou, Theano, Sirsjö, Allan, Koufaki, Maria, Fransén, Karin, Grenegård, Magnus
Published in European journal of pharmacology (15.08.2019)
Published in European journal of pharmacology (15.08.2019)
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Journal Article
Expression of CARD8 in human atherosclerosis and its regulation of inflammatory proteins in human endothelial cells
Paramel, Geena V., Karadimou, Glykeria, Eremo, Anna Göthlin, Ljungberg, Liza U., Hedin, Ulf, Olofsson, Peder S., Folkersen, Lasse, Paulsson-Berne, Gabrielle, Sirsjö, Allan, Fransén, Karin
Published in Scientific reports (05.11.2020)
Published in Scientific reports (05.11.2020)
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Journal Article
Autotaxin-Lysophosphatidic Acid Signaling Contributed to Obesity-Induced Insulin Resistance in Muscle and Impairs Mitochondrial Metabolism
D'Souza, K., Nzirorera, C., Cowie, A.M., Paramel Varghese, Geena, Trivedi, P., Eichmann, T.O., Biswas, D., Touaibia, M., Morris, A.J., Aidinis, V., Kane, D.A., Pulinilkunnil, T., Kienesberger, P.C.
Published in Journal of lipid research (2018)
Published in Journal of lipid research (2018)
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Journal Article
Adverse Cardiometabolic Outcomes in Obese Patients Correlates Strongly with Defective Branched-chain Amino Acid Catabolism
Biswas, Dipsikha, Cowie, Andrew, Tozer, Kathleen, Perez, Lester J., Trivedi, Purvi, Bartlett, Jordan J., Duffley, Luke, Dao, Khoi Thien, Paramel, Geena V., Aguiar, Christie, Yip, Alexandra M., Shea, Jennifer, Brunt, Keith, Legare, Jean-Francois, Hassan, Ansar, Kienesberger, Petra, Pulinilkunnil, Thomas
Published in Journal of molecular and cellular cardiology (01.11.2018)
Published in Journal of molecular and cellular cardiology (01.11.2018)
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